Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Foegh ML et al. | Eicosanoids, gamma-interferon and inflammatory cells in kidney transplant patients. | 1986 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2949550 |
FitzGerald GA et al. | Analysis of urinary metabolites of thromboxane and prostacyclin by negative-ion chemical-ionization gas chromatography/mass spectrometry. | 1985 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2936207 |
Kuzuya T et al. | Determination of plasma thromboxane B2 by radioimmunoassay: methodological problems and accuracy. | 1985 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2936210 |
Pedrinelli R et al. | The influence of selective and nonselective prostaglandin inhibition on renin. | 1985 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:3159197 |
Ezra D et al. | Effects of platelet-activating factor on coronary hemodynamics and coronary venous plasma levels of TXB2, 6-keto-PGF1 alpha, and leukotriene C4 immunoreactivity in the intact domestic pig heart. | 1985 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:3159202 |
Yamamoto S et al. | Enzyme immunoassay of thromboxane B2 and 6-keto-prostaglandin F1 alpha as a substitute for radioimmunoassay. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221523 |
Weerasekera DA et al. | Chemiluminescence immunoassay of thromboxane B2. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221524 |
Ito T et al. | Effects of a selective inhibitor of thromboxane synthetase (OKY-1581) in humans. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221531 |
FitzGerald GA et al. | Aspirin inhibits endogenous prostacyclin and thromboxane biosynthesis in man. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221534 |
van der Giessen WJ et al. | Acute effect of cigarette smoking on cardiac prostaglandin synthesis and platelet behavior in patients with coronary heart disease. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221546 |
Bach MK et al. | In vivo and in vitro actions of a new selective inhibitor of leukotriene C and D synthesis. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221551 |
Grose JH et al. | Imbalanced prostacyclin and thromboxane A2 production in essential hypertension. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221555 |
Hornych A et al. | Thromboxane B2 in borderline and essential hypertension. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221556 |
MacIntyre DE et al. | Role of endogenous arachidonate metabolites in phospholipid-induced human platelet activation. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221557 |
Patrignani P et al. | Characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. | 1995 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:7732817 |
Foegh ML et al. | Urinary thromboxane has diagnostic value in myocardial infarction. | 1995 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:7732879 |
Lesch ME et al. | The effects of (R)-N-(1-methyl-2-phenylethyl) adenosine (L-PIA), a standard A1-selective adenosine agonist on rat acute models of inflammation and neutrophil function. | 1991 | Agents Actions | pmid:1838897 |
Conti P et al. | Augmentation of thromboxane production in vitro by polymorphonuclears and macrophages exposed to IL1/LP. | 1986 | Agents Actions | pmid:3485895 |
Srivastava R et al. | Prostanoid mediated effects of centchroman, a non-steroidal oral contraceptive. | 1986 | Agents Actions | pmid:3532722 |
Hoult JR et al. | Failure of anti-inflammatory steroids to inhibit prostaglandin release from the hydronephrotic rabbit kidney. | 1986 | Agents Actions | pmid:3962772 |