Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Streptococcal Infections D013290 4 associated lipids
Retinal Diseases D012164 4 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Intracranial Embolism and Thrombosis D002542 5 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Facial Pain D005157 5 associated lipids
Bartter Syndrome D001477 5 associated lipids
Abortion, Habitual D000026 5 associated lipids
Mastocytosis D008415 5 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Hypercapnia D006935 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Asthenia D001247 5 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Sclerosis D012598 5 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
beta-Thalassemia D017086 5 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Placenta Diseases D010922 5 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Coronary Stenosis D023921 6 associated lipids
Sneezing D012912 6 associated lipids
Thromboembolism D013923 6 associated lipids
Bronchitis D001991 6 associated lipids
Intermittent Claudication D007383 6 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Thrombophilia D019851 6 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Tachycardia D013610 7 associated lipids
Dyslipidemias D050171 7 associated lipids
Keratitis D007634 7 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Varicose Veins D014648 7 associated lipids
Behcet Syndrome D001528 7 associated lipids
Agranulocytosis D000380 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Femoral Fractures D005264 7 associated lipids
Raynaud Disease D011928 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Obesity, Morbid D009767 8 associated lipids
Fistula D005402 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Mäkilä UM et al. Regulation of prostacyclin and thromboxane production by human umbilical vessels: the effect of estradiol and progesterone in a superfusion model. 1982 Prostaglandins Leukot Med pmid:7043492
Krausz MM et al. Adverse effects of prostacyclin used to perfuse isolated lung lobes. 1982 Am. J. Physiol. pmid:7044149
Siess W et al. Plasma catecholamines, platelet aggregation and associated thromboxane formation after physical exercise, smoking or norepinephrine infusion. 1982 Circulation pmid:7044612
Chierchia S et al. Failure of thromboxane A2 blockade to prevent attacks of vasospastic angina. 1982 Circulation pmid:7116586
Sasagawa S et al. Effects of thromboxane A2 injection on the rabbit coronary artery. I. Physiologic effects in healthy animals. 1982 Exp. Mol. Pathol. pmid:7117494
Socini A et al. Effects of the coumarin derivative AD6 on platelet aggregation, platelet vessel wall interactions and 6 keto PGF1 alpha production in perfused aortas, in experimentally hypercholesterolaemic rabbits. 1982 Pharmacol Res Commun pmid:7048340
Fantone JC et al. Inhibition of vascular permeability changes in rats by captopril. 1982 J. Clin. Invest. pmid:6282931
Ylikorkala O and Viinikka L Effect of amnioscopy on concentrations of prostaglandin F2 alpha, prostacyclin and thromboxane in maternal plasma. 1982 Gynecol. Obstet. Invest. pmid:6954125
Simpson RM et al. Generation of thromboxane A2 and aorta-contracting activity from platelets stimulated with modified C-reactive protein. 1982 Immunology pmid:7118160
Leach CM and Thorburn GD A comparative study of collagen induced thromboxane release from platelets of different species: implications for human atherosclerosis models. 1982 Prostaglandins pmid:7122912
Bottoms GD et al. Thromboxane, prostaglandin I2 (epoprostenol), and the hemodynamic changes in equine endotoxin shock. 1982 Am. J. Vet. Res. pmid:7049018
Poubelle P et al. [Mononucleated phagocytes from rheumatoid synovial fluid. Synthesis of prostanoids and first pharmacological applications]. 1982 Rev Rhum Mal Osteoartic pmid:7123126
Homma T and Malik KU Effect of prostaglandins on pancreatic circulation in anesthetized dogs. 1982 J. Pharmacol. Exp. Ther. pmid:7050343
Bradlow BA and Chetty N Dosage frequency for suppression of platelet function by low dose aspirin therapy. 1982 Thromb. Res. pmid:7123514
Buchanan MR et al. Aspirin inhibits platelet function independent of the acetylation of cyclo-oxygenase. 1982 Thromb. Res. pmid:7071811
Tremoli E et al. Metformin reduces platelet hypersensitivity in hypercholesterolemic rabbits. 1982 Atherosclerosis pmid:7073794
Tanabe M et al. Coronary circulatory failure and thromboxane A2 release during coronary occlusion and reperfusion in anaesthetised dogs. 1982 Cardiovasc. Res. pmid:7074670
Fitzpatrick FA A radioimmunoassay for thromboxane B2. 1982 Meth. Enzymol. pmid:7132759
Maas RL et al. Quantitative assay of urinary 2,3-dinor thromboxane B2 by GC-MS. 1982 Meth. Enzymol. pmid:7132771
Pace-Asciak CR and Edwards NS Preparation of 2,3,4,5-tetranor-thromboxane B2, the major urinary catabolite of thromboxane B2 in the rat. 1982 Meth. Enzymol. pmid:7132772
Martin JF et al. Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique. 1982 Thromb. Res. pmid:6814004
Dorsch W et al. Mediator studies in skin blister fluid from patients with dual skin reactions after intradermal allergen injection. 1982 J. Allergy Clin. Immunol. pmid:6181112
Hadding U et al. Peritoneal macrophages release prostaglandin E and thromboxane B2 in response to C3b. 1982 Adv. Exp. Med. Biol. pmid:7158499
Shaw JO and Lyons RM Requirement for different Ca2+ pools in the activation of rabbit platelets II. Phospholipase activity. 1982 Biochim. Biophys. Acta pmid:6800410
Addonizio VP et al. Inhibition of human platelet function by verapamil. 1982 Thromb. Res. pmid:7164035
Strano A et al. Platelet sensitivity to prostacyclin and thromboxane production in hyperlipidemic patients. 1982 Thromb. Haemost. pmid:6753232
Vargaftig BB et al. Adrenaline and PAF-acether synergize to trigger cyclooxygenase-independent activation of plasma-free human platelets. 1982 Thromb. Res. pmid:7164036
Flynn JT and Demling RH Inhibition of endogenous thromboxane synthesis by exogenous prostacyclin during endotoxemia in conscious sheep. 1982 Adv Shock Res pmid:6753534
Smith MC et al. Prostacyclin substitution for heparin in long-term hemodialysis. 1982 Am. J. Med. pmid:6753575
Zipser RD and Martin K Urinary excretion of arterial blood prostaglandins and thromboxanes in man. 1982 Am. J. Physiol. pmid:6950668
Ylikorkala O et al. Prostacyclin and thromboxane in chronic uremia: effect of hemodialysis. 1982 Clin. Nephrol. pmid:6754193
Ylikorkala O et al. Production of prostacyclin and thromboxane during cesarean section. 1982 Obstet Gynecol pmid:6755324
Utsunomiya T et al. Modification of inflammatory response to aspiration with ibuprofen. 1982 Am. J. Physiol. pmid:6756172
Tooke JE et al. Aspirin, prostacyclin and post-occlusive reactive hyperaemia in man. 1982 Prostaglandins Leukot Med pmid:6757966
Herman CA et al. Prostaglandins of the one, two, and three series affect blood pressure in the american bullfrog, Rana catesbeiana. 1982 Gen. Comp. Endocrinol. pmid:6761235
Davì G et al. Thromboxane B2 formation and platelet sensitivity to prostacyclin in insulin-dependent and insulin-independent diabetics. 1982 Thromb. Res. pmid:6761893
Goldsmith JC and Needleman SW A comparative study of thromboxane and prostacyclin release from ex vivo and cultured bovine vascular endothelium. 1982 Prostaglandins pmid:6815717
Blackwell GJ et al. Prostacyclin prolongs viability of washed human platelets. 1982 Biochim. Biophys. Acta pmid:6291622
Panganamala RV and Cornwell DG The effects of vitamin E on arachidonic acid metabolism. 1982 Ann. N. Y. Acad. Sci. pmid:6816121
Karmali RA et al. Prostaglandin regulation of murine mammary tumor virus production: a basis for some of the glucocorticoid and prolactin actions on mammary tumor cell cultures. 1982 Prostaglandins Leukot Med pmid:6296884
Mitrovic D et al. The in vitro production of prostanoids by cultured bovine articular chondrocytes. 1982 Prostaglandins pmid:6801735
Hornych A et al. Radioimmunoassay measurement of thromboxane B2 in human plasma and urine. 1982 Prostaglandins Leukot Med pmid:6954551
Mest HJ et al. Influence of mental stress on plasma level of prostaglandins, thromboxane B2 and on circulating platelet aggregates in man. 1982 Prostaglandins Leukot Med pmid:6955811
Karmali RA et al. Macrophage production of prostaglandins: effects of fetal calf serum and diazepam. Use of an improved method for extracting 6-keto-PGF1 alpha. 1982 Prostaglandins Leukot Med pmid:6955812
Mehta J et al. Severe intracoronary thromboxane release preceding acute coronary artery occlusion. 1982 Prostaglandins Leukot Med pmid:6955814
Watanabe T et al. Characterization of the biosynthetic pathway of prostaglandin D2 in human platelet-rich plasma. 1982 J. Biol. Chem. pmid:6816798
Jaweed MM et al. Changes in thromboxane B2 and 6-keto-PGF1 alpha after direct electrical stimulation of the denervated rat gastrocnemius1,2. 1982 Prostaglandins Leukot Med pmid:6956927
Taube C et al. Enhanced thromboxane production in the aorta of spontaneously hypertensive rats in vitro. 1982 Prostaglandins Leukot Med pmid:6960370
Castaldi PA et al. Evidence for a platelet membrane defect in the myeloproliferative syndromes. 1982 Thromb. Res. pmid:6960545
Numano F et al. Changes in the plasma levels of thromboxane B2 and cyclic nucleotides in patients with Takayasu disease. 1982 Jpn. Circ. J. pmid:6119373
Foegh ML et al. Aspirin inhibition of thromboxane release in thrombosis and renal transplant rejection. 1982 Lancet pmid:6119441
Graham RM et al. Effects of short-term beta blockade on blood pressure, plasma thromboxane B2, and plasma and urinary prostaglandins E2 and F2 alpha in normal subjects. 1982 Clin. Pharmacol. Ther. pmid:6120775
Rachmilewitz D et al. Prostanoid synthesis by cultured peripheral blood mononuclear cells in inflammatory diseases of the bowel. 1982 Gastroenterology pmid:6949849
Reines HD et al. Plasma thromboxane concentrations are raised in patients dying with septic shock. 1982 Lancet pmid:6123885
Capitanio A et al. Detection of circulating released platelets after renal transplantation. 1982 Transplantation pmid:6461116
White JG and Rao GH Effects of a microtubule stabilizing agent on the response of platelets to vincristine. 1982 Blood pmid:6124288
Chong BH et al. Heparin-induced thrombocytopenia: association of thrombotic complications with heparin-dependent IgG antibody that induces thromboxane synthesis in platelet aggregation. 1982 Lancet pmid:6128550
Di Minno G et al. Arachidonic acid induces human platelet-fibrin retraction: the role of platelet cyclic endoperoxides. 1982 Thromb. Res. pmid:6803385
Suehiro A et al. The role of platelet hyperfunction in thrombus formation in hyperlipidemia. 1982 Thromb. Res. pmid:6803387
Ody C et al. 6-Ketoprostaglandin F1 alpha, prostaglandins E2, F2 alpha and thromboxane B2 production by endothelial cells, smooth muscle cells and fibroblasts cultured from piglet aorta. 1982 Biochim. Biophys. Acta pmid:6214281
Rock JA et al. Cul-de-sac fluid in women with endometriosis: fluid volume and prostanoid concentration during the proliferative phase of the cycle--days 8 to 12. 1982 Fertil. Steril. pmid:6953017
Casey LC et al. Prevention of endotoxin-induced pulmonary hypertension in primates by the use of a selective thromboxane synthetase inhibitor, OKY 1581. 1982 J. Pharmacol. Exp. Ther. pmid:6896528
Chen LS et al. Changes of plasma 6-keto-PGF1 alpha and thromboxane B2 levels and platelet aggregation after tourniquet ischemia on the upper limb in normal subjects and patients with ischemic heart disease. 1982 Jpn. Circ. J. pmid:6896534
Mehta P et al. Comparison of umbilical vein models for measurement of relative prostacyclin and thromboxane production. 1982 Prostaglandins pmid:6820165
Stuart MJ and Allen JB Arachidonic acid metabolism in the neonatal platelet. 1982 Pediatrics pmid:6804924
Evans CA et al. Gestational changes in prostanoid concentrations in intrauterine tissues and fetal fluids from pregnant sheep, and the relation to prostanoid output in vitro. 1982 Biol. Reprod. pmid:6896829
Nolan RD et al. The pericardium as a source of prostacyclin in the dog, ox and rat. 1982 Prostaglandins pmid:6820168
Koyama I et al. Release of 6-keto-prostaglandin F1 alpha and thromboxane B2 from mouse peritoneal macrophages during their adhesion and spreading on a glass surface. 1982 Prostaglandins pmid:6896924
Whinnery MA et al. Thromboxane B2 and prostaglandin E2 in the rat kidney with unilateral ureteral obstruction. 1982 Am. J. Physiol. pmid:6950670
Hwang DH and Donovan J In vitro and in vivo effects of vitamin E on arachidonic acid metabolism in rat platelets. 1982 J. Nutr. pmid:6806455
McNamara DB et al. Prostaglandin endoperoxide metabolism by microsomes of whole kidneys from normal, congenital unilateral hydronephrotic and unilateral ureteral obstructed rats. 1982 Prostaglandins pmid:6962465
Hornych A et al. [Urinary thromboxane B2 in hypertensive patients]. 1982 Arch Mal Coeur Vaiss pmid:6810812
Worthington RE and Nakeff A Aspirin inhibits rat megakaryocyte thromboxane synthesis. 1982 Prostaglandins pmid:6812167
Havill AM et al. alpha-Naphthylthiourea produces dose-dependent lung vascular injury in sheep. 1982 Am. J. Physiol. pmid:6812437
Lecompte T et al. Interference of transmethylation inhibitors with thromboxane synthesis in rat platelets. 1982 Biochem. Biophys. Res. Commun. pmid:6809005
Preston FE et al. Low-dose aspirin inhibits platelet and venous cyclo-oxygenase in man. 1982 Thromb. Res. pmid:6815823
Burch RM and Halushka PV Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells. 1982 Am. J. Physiol. pmid:6816073
Patrignani P et al. Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects. 1982 J. Clin. Invest. pmid:7045161
Bakhle YS and Zakrzewski JT Effects of the oestrous cycle on the metabolism of arachidonic acid in rat isolated lung. 1982 J. Physiol. (Lond.) pmid:6809935
Steel LK and Catravas GN Radiation-induced changes in production of prostaglandins F2 alpha, E, and thromboxane B2 in guinea pig parenchymal lung tissues. 1982 Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. pmid:6818175
Meydani SN and Dupont J Effect of zinc deficiency on prostaglandin synthesis in different organs of the rat. 1982 J. Nutr. pmid:7045297
Srivastava KC and Awasthi KK A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-14C) arachidonic acid. 1982 Prostaglandins Leukot Med pmid:6818563
Neri Serheri GG et al. Platelet aggregation and thromboxane A2 production after adrenergic stimulation in young healthy humans. 1982 Haemostasis pmid:6279476
Watkins WD et al. Thromboxane and pulmonary hypertension following E. coli endotoxin infusion in sheep: effect of an imidazole derivative. 1982 Prostaglandins pmid:7048422
Dore-Duffy P Differential effect of prostaglandins and other products of arachidonic acid metabolism on measles virus replication in Vero cells. 1982 Prostaglandins Leukot Med pmid:6281810
Kelley VE et al. Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus. 1982 Clin. Immunol. Immunopathol. pmid:6819912
Miller OV et al. Acetyl glycerylphosphorylcholine inhibition of prostaglandin I2-stimulated adenosine 3',5'-cyclic monophosphate levels in human platelets. Evidence for thromboxane A2 dependence. 1982 Biochim. Biophys. Acta pmid:6285985
Hüttemeier PC et al. Acute pulmonary hypertension and lung thromboxane release after endotoxin infusion in normal and leukopenic sheep. 1982 Circ. Res. pmid:7042108
Cerletti C et al. Non-steroidal anti-inflammatory drugs react with two sites on platelet cyclo-oxygenase. Evidence from "in vivo" drug interaction studies in rats. 1982 Biochim. Biophys. Acta pmid:6799004
Kunkel SL et al. Production of cyclooxygenase products and superoxide anion by macrophages in response to chemotactic factors. 1982 Prostaglandins pmid:6300969
Panossian A et al. On the mechanism of biosynthesis of leukotrienes and related compounds. 1982 FEBS Lett. pmid:6297982
Landgraf-Leurs MM et al. Aggregation and thromboxane formation by platelets and vascular prostacyclin production from BB rats. An animal model for type I diabetes. 1982 Prostaglandins pmid:6812171
Bodzenta A et al. Platelet malondialdehyde and plasma thromboxane B2 formation in patients with obliterative arteriosclerosis of the lower limbs. 1982 Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. pmid:6188668
Pawlowski NA et al. Uptake and metabolism of monohydroxy-eicosatetraenoic acids by macrophages. 1982 J. Exp. Med. pmid:6951919
Harada Y et al. Changes in the levels of prostaglandins and thromboxane and their roles in the accumulation of exudate in rat carrageenin-induced pleurisy--a profile analysis using gas chromatography-mass spectrometry. 1982 Prostaglandins pmid:6889754
Yoshimoto T and Yamamoto S Partial purification and assay of thromboxane A synthase from bovine platelets. 1982 Meth. Enzymol. pmid:6890138
Miller JL et al. Arachidonic acid metabolism in guinea pig megakaryocytes. 1982 Biochem. Biophys. Res. Commun. pmid:6812584
Scherhag R et al. Dietary administration of eicosapentaenoic and linolenic acid increases arterial blood pressure and suppresses vascular prostacyclin synthesis in the rat. 1982 Prostaglandins pmid:6285420
Rothberg KG and Hitchcock M In vitro biosynthesis of cyclooxygenase metabolites in ovalbumin-sensitized and control lungs of guinea pigs. 1982 Biochem. Pharmacol. pmid:6812589
Malemud CJ et al. Correlation of the biosynthesis of prostaglandin and cyclic AMP in monolayer cultures of rabbit articular chondrocytes. 1982 Biochim. Biophys. Acta pmid:6280776