Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Heinonen PK and Metsä-Ketelä T | Prostaglandin and thromboxane production in ovarian cancer tissue. | 1984 | Gynecol. Obstet. Invest. | pmid:6396175 |
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Navran SS et al. | Human platelet activation by bacterial phospholipase C is mediated by phosphatidylinositol hydrolysis but not generation of phosphatidic acid: inhibition by a selective inhibitor of phospholipase C. | 1984 | Thromb. Res. | pmid:6372157 |
Furman BL et al. | Failure of drugs that selectively inhibit thromboxane synthesis to modify endotoxin shock in conscious rats. | 1984 | Br. J. Pharmacol. | pmid:6375795 |
Merola AJ et al. | Prostaglandin response in the exercise conditioned rat. | 1984 | Prostaglandins Leukot Med | pmid:6377328 |
Gross S and Worthington-White DA | The effects of PGF2 alpha, PGI2, and TxB2 on human CFU-C in healthy and leukemic patients. | 1984 | Am. J. Hematol. | pmid:6372442 |
Brown CG and Poyser NL | Studies on ovarian prostaglandin production in relation to ovulation in the rat. | 1984 | J. Reprod. Fertil. | pmid:6595406 |
Carter AJ et al. | A comparison of human pulmonary arterial and venous prostacyclin and thromboxane synthesis--effect of a thromboxane synthase inhibitor. | 1984 | Thromb. Haemost. | pmid:6377567 |
Mitrovic D et al. | Anti-inflammatory drugs, prostanoid and proteoglycan production by cultured bovine articular chondrocytes. | 1984 | Prostaglandins | pmid:6595718 |
Salvetti A et al. | The influence of indomethacin and sulindac on some pharmacological actions of atenolol in hypertensive patients. | 1984 | Br J Clin Pharmacol | pmid:6378233 |
Kirton OC et al. | The development of a model of subacute lung injury after intra-abdominal infection. | 1984 | Surgery | pmid:6379962 |
Roy AC et al. | Thromboxane A2 and prostacyclin levels in molar pregnancy. | 1984 | Br J Obstet Gynaecol | pmid:6383461 |
Walinsky P et al. | Thromboxane A2 in acute myocardial infarction. | 1984 | Am. Heart J. | pmid:6485997 |
Runkle B et al. | Cardiovascular changes in group B streptococcal sepsis in the piglet: response to indomethacin and relationship to prostacyclin and thromboxane A2. | 1984 | Pediatr. Res. | pmid:6384909 |
D'Angelo A et al. | Increased production of platelet thromboxane B2 in non-insulin-dependent diabetes. Relationship to vascular complications. | 1984 | Eur. J. Clin. Invest. | pmid:6428908 |
Schenkein HA and Rutherford RB | Effects of serum on C3b-stimulated release of prostaglandins and thromboxane B2 from human monocytes. | 1984 | Immunopharmacology | pmid:6511367 |
Fung WP et al. | Effect of ethanol on gastric secretion of thromboxane B2. | 1984 | Med. J. Malaysia | pmid:6513851 |
Watanabe J et al. | Effect of prostaglandin synthetase inhibitors on platelet aggregation and thromboxane production in diabetes mellitus. | 1984 | Tohoku J. Exp. Med. | pmid:6515648 |
Ditter H and Matthias FR | Changes in thromboxane formation by platelets during and after a continuous endotoxin infusion into rabbits. | 1984 | VASA | pmid:6516562 |
Fitscha P et al. | Follow-up of in-vivo platelet function (platelet half-life, thromboxane B2) in patients with coronary heart disease. | 1984 | VASA | pmid:6516563 |
Block HU et al. | Estimation of thromboxane B2 in the clotting human whole blood by gas chromatography. | 1984 | Biomed. Biochim. Acta | pmid:6517904 |
Beitz A et al. | Thromboxane B2 (TXB2) formation in clotting whole blood of healthy and diabetic humans in vitro. | 1984 | Biomed. Biochim. Acta | pmid:6517908 |
Keinänen-Kiukaanniemi S et al. | Decreased thromboxane production in migraine patients during headache-free period. | 1984 | Headache | pmid:6519984 |
Uotila P et al. | Prostanoids and hemodynamics in man before and during cardiopulmonary bypass. | 1984 | Prostaglandins | pmid:6335260 |
Hänsch GM et al. | Macrophages release arachidonic acid, prostaglandin E2, and thromboxane in response to late complement components. | 1984 | J. Immunol. | pmid:6432907 |
Robson MC et al. | A new explanation for the progressive tissue loss in electrical injuries. | 1984 | Plast. Reconstr. Surg. | pmid:6422484 |
Rachmilewitz D and Karmeli F | Effect of nufenoxole on human colonic prostanoid synthesis, Na-K-ATPase and adenylate cyclase activities. | 1984 | Eur. J. Pharmacol. | pmid:6152213 |
Stock JL and Coderre JA | Calcitonin enhances production of prostaglandins by stimulated human monocytes. | 1984 | Prostaglandins | pmid:6087420 |
Yui Y et al. | Intravenous infusion of a selective inhibitor of thromboxane A2 synthetase in man: influence on thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and platelet aggregation. | 1984 | Circulation | pmid:6434196 |
Koike K et al. | Platelet secretion defect in patients with the attention deficit disorder and easy bruising. | 1984 | Blood | pmid:6692042 |
Lee EC et al. | Functional responses of tumor cells to phorbol esters: role for prostaglandins. | 1984 | Oncology | pmid:6587276 |
Jackson CA et al. | Near-normal glycaemic control does not correct abnormal platelet reactivity in diabetes mellitus. | 1984 | Clin. Sci. | pmid:6434224 |
Vesterqvist O et al. | Development of a GC-MS method for quantitation of 2,3-dinor-TxB2 and determinations of the daily urinary excretion rates in healthy humans. | 1984 | Thromb. Res. | pmid:6695361 |
Davì G et al. | Platelet function changes in acute myocardial infarction. | 1984 | Adv. Exp. Med. Biol. | pmid:6695571 |
Mehta J et al. | Thromboxane release in coronary artery disease: spontaneous versus pacing-induced angina. | 1984 | Am. Heart J. | pmid:6695662 |
Klotz TA et al. | Urinary excretion of thromboxane B2 in patients with venous thromboembolic disease. | 1984 | Chest | pmid:6697787 |
Maddox Y et al. | A routine source of human peritoneal macrophages. | 1984 | Scand. J. Immunol. | pmid:6701470 |
Salmon JA et al. | Benoxaprofen does not inhibit formation of leukotriene B4 in a model of acute inflammation. | 1984 | Biochem. Pharmacol. | pmid:6089840 |
Dembinska-Kieć A et al. | Formation of leukotriene C4-like material by rat brain tissue. | 1984 | Eur. J. Pharmacol. | pmid:6426980 |
Stuart MJ et al. | Effects of hyperoxia and hypoxia on vascular prostacyclin formation in vitro. | 1984 | Pediatrics | pmid:6435087 |
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Vergani CG et al. | Bile lipid composition and haemostatic variables in a case of high density lipoprotein deficiency (Tangier disease). | 1984 | Eur. J. Clin. Invest. | pmid:6421598 |
Serhan CN et al. | Formation of leukotrienes and hydroxy acids by human neutrophils and platelets exposed to monosodium urate. | 1984 | Prostaglandins | pmid:6328582 |
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Simberg N | Maternal aspirin administration inhibits pulmonary arachidonic acid metabolism in fetal rabbits. | 1984 | Prostaglandins Leukot Med | pmid:6425868 |
Rao GH et al. | Enteric-coated aspirin, platelet cyclooxygenase activity and function. | 1984 | Prostaglandins Leukot Med | pmid:6425869 |
Burghuber O et al. | Lung edema due to hydrogen peroxide is independent of cyclooxygenase products. | 1984 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6427146 |
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Brandt R et al. | Effect of propranolol, practolol and atenolol on human platelet thromboxane formation and plasma levels of prostaglandins 6-keto-F1 alpha and E2. | 1984 | Prostaglandins Leukot Med | pmid:6597450 |
Chiba S et al. | Sex and age-related differences in the urinary excretion of TXB2 in normal human subjects: a possible pathophysiological role of TXA2 in the aged kidney. | 1984 | Prostaglandins Leukot Med | pmid:6597456 |
Mahmud I et al. | Thromboxane synthesizing system in rat liver. | 1984 | Prostaglandins Leukot Med | pmid:6597457 |
Morrison AR and Crowley JR | Identification of an unusual cyclooxygenase metabolite of arachidonic acid in rabbit renal medulla. | 1984 | Arch. Biochem. Biophys. | pmid:6437329 |
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Axelrod L and Cornelius P | Plasma prostaglandin levels and circulating fuel levels in rats with diabetic ketoacidosis: effects of cyclooxygenase inhibitors and of alpha and beta adrenergic blockade. | 1984 | Prostaglandins | pmid:6440213 |
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Higgins AJ and Lees P | Arachidonic acid metabolites in carrageenin-induced equine inflammatory exudate. | 1984 | J. Vet. Pharmacol. Ther. | pmid:6423835 |
Coker SJ | Further evidence that thromboxane exacerbates arrhythmias: effects of UK38485 during coronary artery occlusion and reperfusion in anaesthetized greyhounds. | 1984 | J. Mol. Cell. Cardiol. | pmid:6433026 |
Krell RD and Kusner EJ | Differential effect of cyclo-oxygenase inhibition on antigen- and ionophore-induced release of slow reacting substance from fragmented guinea-pig lung. | 1984 | Br. J. Pharmacol. | pmid:6434013 |
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Galli C et al. | Acute effects of ethanol, caffeine, or both on platelet aggregation, thromboxane formation, and plasma-free fatty acids in normal subjects. | 1984 | Drug Nutr Interact | pmid:6510241 |
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Lefer AM et al. | Pathophysiological mechanisms of sudden death induced by platelet activating factor. | 1984 | Br. J. Pharmacol. | pmid:6435705 |
Cremer KF et al. | Effects of diltiazem, dipyridamole, and their combination on hemostasis. | 1984 | Clin. Pharmacol. Ther. | pmid:6435926 |
Gal D et al. | Effect of radiation on prostaglandin production by human bowel in vitro. | 1984 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:6588048 |
Oglesby TD and Gorman RR | The inhibition of arachidonic acid metabolism in human platelets by RHC 80267, a diacylglycerol lipase inhibitor. | 1984 | Biochim. Biophys. Acta | pmid:6424715 |
Pedersen AK and FitzGerald GA | Dose-related kinetics of aspirin. Presystemic acetylation of platelet cyclooxygenase. | 1984 | N. Engl. J. Med. | pmid:6436696 |
Rehr RB et al. | Mechanism of nitroglycerin-induced coronary dilatation: lack of relation to intracoronary thromboxane concentrations. | 1984 | Am. J. Cardiol. | pmid:6437206 |