Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
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Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Spagnuolo PJ et al. | Thromboxane A2 mediates augmented polymorphonuclear leukocyte adhesiveness. | 1980 | J. Clin. Invest. | pmid:6772674 |
| Best LC et al. | The interrelationship between thromboxane biosynthesis, aggregation and 5-hydroxytryptamine secretion in human platelets in vitro. | 1980 | Thromb. Haemost. | pmid:6773171 |
| Olund A et al. | Prostaglandins and thromboxanes in amniotic fluid during rivanol-induced abortion and labour. | 1980 | Prostaglandins | pmid:6775353 |
| Bisordi JE et al. | Interaction of vasopressin and prostaglandins in the toad urinary bladder. | 1980 | J. Clin. Invest. | pmid:6777397 |
| Stuart MJ et al. | The influence of albumin and calcium on human platelet arachidonic acid metabolism. | 1980 | Blood | pmid:6766753 |
| Challis JR and Patrick JE | The production of prostaglandins and thromboxanes in the feto-placental unit and their effects on the developing fetus. | 1980 | Semin. Perinatol. | pmid:6992278 |
| Ahnfelt-Rønne I et al. | Macrophages from adjuvent arthritic rats preferentially synthetize prostacyclin. | 1980 | Agents Actions | pmid:6992544 |
| Gullner HG et al. | Correction of increased prostacyclin synthesis in Bartter's syndrome by indomethacin treatment. | 1980 | Prostaglandins Med | pmid:6994153 |
| Brodie MJ et al. | Is prostacyclin in the major pro-inflammatory prostanoid in joint fluid? | 1980 | Life Sci. | pmid:6999274 |
| Heggers JP et al. | Evaluation of burn blister fluid. | 1980 | Plast. Reconstr. Surg. | pmid:6770396 |
| Mathé AA et al. | Increased content of immunoreactive prostaglandin E in cerebrospinal fluid of patients with schizophrenia. | 1980 | Lancet | pmid:6101355 |
| Mestel F et al. | Severe bleeding associated with defective thromboxane synthetase. | 1980 | Lancet | pmid:6101498 |
| Pareti FI et al. | Platelets and the vessel wall: how much aspirin? | 1980 | Lancet | pmid:6101829 |
| Sanger GJ and Bennett A | Trimethoquinol selectively antagonizes contractions of rat gastric fundus to TXB2 and epoxymethano analogs of PGH2. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6103666 |
| Zahavi J et al. | Enhanced in-vivo platelet release reaction, increased thromboxane synthesis, and decreased prostacyclin release after tourniquet ischaemia. | 1980 | Lancet | pmid:6106784 |
| Galli C et al. | Effects of 8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxy carboxyl methoxy coumarin (AD6) on aggregation, arachidonic acid metabolism and thromboxane B2 formation in human platelets. | 1980 | Pharmacol Res Commun | pmid:7393988 |
| Chiabrando C et al. | Quantitative determination of 6-keto-PGF1 alpha released by rat aorta: comparison of mass fragmentography and high resolution gas chromatography with electron capture detection. | 1980 | Prostaglandins | pmid:6894036 |
| Oka M and Manku MS | Spironolactone decreases the formation of prostaglandins and related substances from arachidonic acid in rat vascular rings and human platelets. | 1980 | Prostaglandins Med | pmid:7394062 |
| Karmali RA et al. | Intrarenal growth of the Walker 256 tumour and renal vein concentrations of PGE2, PGF 2 alpha, and TXB2: effects of diazepam. | 1980 | Prostaglandins Med | pmid:7394064 |
| Cooper JD et al. | Prostaglandin production associated with the pulmonary vascular response to complement activation. | 1980 | Surgery | pmid:7394704 |
| Lindgren JA et al. | Effects of platelet aggregation and adenosine 3':5'-monophosphate on the synthesis of thromboxane B2 in human platelets. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6247886 |
| Lagarde M et al. | Nicergoline, an anti-aggregating agent which inhibits release of arachidonic acid from human platelet phospholipids. | 1980 | Prostaglandins | pmid:7384555 |
| Patrono C et al. | Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386257 |
| Langs DA et al. | Thromboxane molecules are not hairpin conformers. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386281 |
| Bailey JM | Essential fatty acid requirements and metabolism of cells in tissue culture. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386288 |
| Maggi FM et al. | Prostaglandin synthetase activity in vascular tissue of male and female rats. | 1980 | Prostaglandins | pmid:6770422 |
| Feinstein MB et al. | Serine-esterase (protease) inhibitors block stimulus-induced mobilization of arachidonate in platelets. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6770602 |
| Cook JA et al. | Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency. | 1980 | J. Clin. Invest. | pmid:7350199 |
| Stuart MJ et al. | Effect of cholesterol on production of thromboxane b2 by platelets in vitro. | 1980 | N. Engl. J. Med. | pmid:7350406 |
| Maclouf J et al. | Interactions of prostaglandin H2 and thromboxane A2 with human serum albumin. | 1980 | Eur. J. Biochem. | pmid:7408901 |
| Wise WC et al. | Ibuprofen improves survival from endotoxic shock in the rat. | 1980 | J. Pharmacol. Exp. Ther. | pmid:7452480 |
| Vanderhoek JY et al. | 15-hydroxy-5,8,11,13-eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase. | 1980 | J. Biol. Chem. | pmid:6771259 |
| Ali M et al. | Inhibition of human platelet cyclooxygenase by alpha-tocopherol. | 1980 | Prostaglandins Med | pmid:6771778 |
| Kosaki G et al. | The mechanism of the inhibitory effect of protease inhibitors on platelet aggregation and cellular synthesis of prostaglandins. I. The effect on the release of arachidonic acid from phospholipids. | 1980 Dec 1-15 | Thromb. Res. | pmid:6785893 |
| Patrono C et al. | Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. | 1980 Feb 1-15 | Thromb. Res. | pmid:7368167 |
| Koh H et al. | A radioimmunoassay of thromboxane B2 with thromboxane B2-125I-tyramide and its application to the study on the thromboxane B2 formation during platelet aggregation. | 1980 Feb 1-15 | Thromb. Res. | pmid:7368170 |
| Boyd JA and Eling TE | Prostaglandin release and the interaction of platelets with the pulmonary vasculature of rat and guinea pig. | 1980 Jul 1-15 | Thromb. Res. | pmid:7003800 |
| Bockman RS | Prostaglandin production by human blood monocytes and mouse peritoneal macrophages: synthesis dependent on in vitro culture conditions. | 1981 | Prostaglandins | pmid:6782622 |
| Rittenhouse-Simmons S | Differential activation of platelet phospholipases by thrombin and ionophore A23187. | 1981 | J. Biol. Chem. | pmid:6783655 |
| Galli C et al. | Differential effects of dietary fatty acids on the accumulation of arachidonic acid and its metabolic conversion through the cyclooxygenase and lipoxygenase in platelets and vascular tissue. | 1981 | Lipids | pmid:6783805 |
| Rao GH et al. | Effect of Amrinone, a cardiotonic drug, on hemodynamics and platelet function. | 1981 | Prostaglandins Med | pmid:6784136 |
| Strand JC et al. | Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. | 1981 | Am. J. Physiol. | pmid:6787931 |
| Stuart MJ et al. | Abnormal platelet function and arachidonate metabolism in chronic idiopathic thrombocytopenic purpura. | 1981 | Blood | pmid:6788109 |
| Shaw JO et al. | Activation of rabbit platelet phospholipase and thromboxane synthesis by 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (platelet activating factor). | 1981 | Biochim. Biophys. Acta | pmid:7213765 |
| Kass MA et al. | Prostaglandin and thromboxane synthesis by microsomes of inflamed rabbit ciliary body--iris. | 1981 | Invest. Ophthalmol. Vis. Sci. | pmid:7216665 |
| Sakio H et al. | [Release of thromboxane A2 during hemorrhagic shock (author's transl)]. | 1981 | Masui | pmid:7218508 |
| Kawaguchi H et al. | Thromboxane B2 biosynthesis and phospholipids hydrolysis in platelets from hypercholesterolemic rabbits. | 1981 | Lipids | pmid:7219079 |
| Sirois P et al. | Comparative effects of leukotriene B4, prostaglandins I2 and E2, 6-keto-PGF1 alpha thromboxane B2 and histamine on selected smooth muscle preparations. | 1981 | J. Pharm. Pharmacol. | pmid:6115037 |
| Handin RI and Alexander RW | Humoral heartache -- do platelets have a role? | 1981 | N. Engl. J. Med. | pmid:7010170 |
| Robertson RM et al. | Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials. | 1981 | N. Engl. J. Med. | pmid:7010173 |
| Hladovec J | Prostaglandins and endothelial stability. | 1981 | Arzneimittelforschung | pmid:7011332 |
| Sananès N et al. | A role for prostaglandins in decidualization of the rat uterus. | 1981 | J. Endocrinol. | pmid:7012263 |
| Coker SJ et al. | Aspirin inhibits the early myocardial release of thromboxane B2 and ventricular ectopic activity following acute coronary artery occlusion in dogs. | 1981 | Br. J. Pharmacol. | pmid:7284679 |
| Tyler HM et al. | Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase. | 1981 | Lancet | pmid:6110861 |
| Vermylen J et al. | Thromboxane synthetase inhibition as antithrombotic strategy. | 1981 | Lancet | pmid:6112447 |
| Feuerstein N et al. | 3-deazaadenosine, a transmethylase inhibitor, suppresses the effect of lipopolysaccharide on release of prostacyclin and thromboxane. | 1981 | J. Pharm. Pharmacol. | pmid:6115021 |
| Fasce L et al. | [Effects of glucocorticoids on the gastrointestinal tract of normal rats and rats deficient in endogenous prostaglandins]. | 1981 | Boll. Soc. Ital. Biol. Sper. | pmid:7295403 |
| Tada M et al. | Elevation of thromboxane B2 levels in patients with classic and variant angina Pectoris. | 1981 | Circulation | pmid:7296786 |
| Foegh ML et al. | Urine i-TXB2 in renal allograft rejection. | 1981 | Lancet | pmid:6115199 |
| McManus LM et al. | Acetyl glyceryl ether phosphorylcholine. Intravascular alterations following intravenous infusion into the baboon. | 1981 | Lab. Invest. | pmid:7300244 |
| Utsunomiya T et al. | Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA). | 1981 | Ann. Surg. | pmid:6117260 |
| Uyama O et al. | Plasma concentrations of thromboxane B2 in patients with hypertension or cerebrovascular disease. | 1981 | Prostaglandins Med | pmid:7302001 |
| Mahoney DA et al. | Urinary thromboxane B2 on allograft rejection. | 1981 | Lancet | pmid:6118500 |
| Smith JB and Jubiz W | OKY-1581: a selective inhibitor of thromboxane synthesis in vivo and in vitro. | 1981 | Prostaglandins | pmid:7302264 |
| Rifkin BR and Tai HH | Elevated thromboxane B2 levels in periodontal disease. | 1981 | J. Periodont. Res. | pmid:6453981 |
| Mehta J and Mehta P | Significance of platelet function and thromboxane B2 levels across the human myocardial vascular bed. | 1981 | Acta Med. Scand. Suppl. | pmid:6948499 |
| Stenson WF et al. | Metabolism of exogenous arachidonic acid by murine macrophage-like tumor cell lines. | 1981 | Prostaglandins | pmid:6803301 |
| Rubenstein MD et al. | Platelet activation in clinical coronary artery disease and spasm. | 1981 | Am. Heart J. | pmid:6455912 |
| Walker ID et al. | A double blind study of prostacyclin in cardiopulmonary bypass surgery. | 1981 | Br. J. Haematol. | pmid:6457624 |
| Bray MA et al. | Prostaglandin generation by separated human blood mononuclear cell fractions. | 1981 | Int. J. Immunopharmacol. | pmid:6949878 |
| Capitanio A et al. | Platelet abnormalities in renal transplantation. | 1981 | Proc Eur Dial Transplant Assoc | pmid:6460244 |
| Kelly KL and Laychock SG | Prostaglandin synthesis and metabolism in isolated pancreatic islets of the rat. | 1981 | Prostaglandins | pmid:6803305 |
| Ylikorkala O and Viinikka L | Prostacyclin, thromboxane, and prostaglandin F2 alpha in maternal plasma during breast-feeding. | 1981 | Am. J. Obstet. Gynecol. | pmid:7011034 |
| Morrison AR and Benabe JE | Prostaglandins in vascular tone in experimental obstructive nephropathy. | 1981 | Kidney Int. | pmid:6894950 |
| Bombardieri S et al. | The synovial prostaglandin system in chronic inflammatory arthritis: differential effects of steroidal and nonsteroidal anti-inflammatory drugs. | 1981 | Br. J. Pharmacol. | pmid:6895043 |
| Harms BA et al. | Prostaglandin release and altered microvascular integrity after burn injury. | 1981 | J. Surg. Res. | pmid:6895238 |
| Ylikorkala O et al. | Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies. | 1981 | Am. J. Obstet. Gynecol. | pmid:6895277 |
| Ishihara Y et al. | [Effect of hypoxemia and pulmonary thromboembolism on plasma levels of 6-keto PGF 1 alpha, TxB, histamine and serotonin in anesthetized dogs (author's transl)]. | 1981 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:6895531 |
| Kinney EL and Demers LM | Plasma 6 keto PGE1 alpha concentration in Raynaud's phenomenon. | 1981 | Prostaglandins Med | pmid:6895673 |
| Defreyn G et al. | Familial bleeding tendency with partial platelet thromboxane synthetase deficiency: reorientation of cyclic endoperoxide metabolism. | 1981 | Br. J. Haematol. | pmid:6268139 |
| Barnett AH et al. | Circulating prostanoid levels, both basal and during the chlorpropamide alcohol flush, in non-insulin dependent diabetes. | 1981 | Clin. Endocrinol. (Oxf) | pmid:6895721 |
| Morrison AR et al. | Thromboxane A2 is the major arachidonic acid metabolite of human cortical hydronephrotic tissue. | 1981 | Prostaglandins | pmid:6894498 |
| She HS et al. | Metabolism of prostaglandin endoperoxide by microsomes from cat lung. | 1981 | Prostaglandins | pmid:6894797 |
| Agradi E et al. | In vitro effects of synthetic antioxidants and vitamin E on arachidonic acid metabolism and thromboxane formation in human platelets and on platelet aggregation. | 1981 | Prostaglandins | pmid:6794104 |
| Russell NH et al. | Platelet adenine nucleotides and arachidonic acid metabolism in the myeloproliferative disorders. | 1981 | Thromb. Res. | pmid:6794179 |
| Beck N and Shaw JO | Thromboxane B2 and prostaglandin E2 in the K+-depleted rat kidney. | 1981 | Am. J. Physiol. | pmid:7468800 |
| Laviolette M et al. | Human alveolar macrophages: a lesion in arachidonic acid metabolism in cigarette smokers. | 1981 | Am. Rev. Respir. Dis. | pmid:6794395 |
| Hwang DH et al. | In vitro and in vivo effects of ethanol on the formation of endoperoxide metabolites in rat platelets. | 1981 | Lipids | pmid:6792442 |
| Shaw JO | Effects of extracellular Ca2+ and the intracellular Ca2+ antagonist 8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate on rabbit platelet conversion of arachidonic acid into thromboxane. | 1981 | Prostaglandins | pmid:6789402 |
| Tulenko TN | The actions of prostaglandins and cyclo-oxygenase inhibition on the resistance vessels supplying the human fetal placenta. | 1981 | Prostaglandins | pmid:6794096 |
| Ingerman-Wojenski C et al. | Prostacyclin production in rabbit arteries in situ: inhibition by arachidonic acid-induced endothelial cell damage or by low-dose aspirin. | 1981 | Prostaglandins | pmid:6789404 |
| Williamson EM et al. | Studies on the mechanism of action of 12-deoxyphorbolphenylacetate, a potent platelet aggregating tigliane ester. | 1981 | Biochem. Pharmacol. | pmid:6794576 |
| Ylikorkala O et al. | Prostacyclin and thromboxane in diabetes. | 1981 | Br Med J (Clin Res Ed) | pmid:6794795 |
| Lee SH et al. | Prostacyclin and thromboxane A2 in thrombotic thrombocytopenic purpura. | 1981 | Br Med J (Clin Res Ed) | pmid:6797537 |
| Morris HG et al. | Variables associated with radioimmunoassay of prostaglandins in plasma. | 1981 | Prostaglandins | pmid:6803306 |
| Feuerstein N and Ramwell PW | OKY-1581, a potential selective thromboxane synthetase inhibitor. | 1981 | Eur. J. Pharmacol. | pmid:7195815 |
| Satoh H et al. | Influence of angiotensins (I, II & III) on prostaglandin production by minced rat renal medulla. | 1981 | Prostaglandins | pmid:7197382 |
| Steinhauer HB and Hertting G | Lowering of the convulsive threshold by non-steroidal anti-inflammatory drugs. | 1981 | Eur. J. Pharmacol. | pmid:7202518 |
| Robson MC and Heggers JP | Evaluation of hand frostbite blister fluid as a clue to pathogenesis. | 1981 | J Hand Surg Am | pmid:7204918 |
| Subbiah MT et al. | Effect of specific estrogens on prostaglandin synthesis in aorta and thrombocytes of female pigeons. | 1981 | Proc. Soc. Exp. Biol. Med. | pmid:7208490 |