Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kowalska MA et al. | Stromal cell-derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets. | 2000 | Blood | pmid:10891429 |
Bailey SR et al. | Differential activation of platelets from normal and allergic ponies by PAF and ADP. | 2000 | Inflamm. Res. | pmid:10893045 |
Rao AR and Prabhakar MC | Screening methods for antiasthmatic agents. | 2000 | Methods Find Exp Clin Pharmacol | pmid:10893704 |
Cayatte AJ et al. | The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo E-deficient mice: evidence that eicosanoids other than thromboxane contribute to atherosclerosis. | 2000 | Arterioscler. Thromb. Vasc. Biol. | pmid:10894809 |
Sugimoto KI et al. | Delayed hypotensive effect of the thromboxane A2/prostaglandin H2 receptor antagonist S-1452 in spontaneously hypertensive rats. | 2000 | Clin. Exp. Pharmacol. Physiol. | pmid:10901388 |
Köfeler HC et al. | Effect of cytochrome P-450 inhibitors econazole, bifonazole and clotrimazole on prostanoid formation. | 2000 | Br. J. Pharmacol. | pmid:10903961 |
Toft G et al. | Intravenously and topically applied magnesium in the prevention of arterial thrombosis. | 2000 | Thromb. Res. | pmid:10904104 |
Giedrojć J et al. | [Investigation of prostaglandins in supernatant of cultured monocytes]. | 2000 | Prz. Lek. | pmid:10907365 |
Momi S et al. | Involvement of platelets in experimental mouse trypanosomiasis: evidence of mouse platelet cytotoxicity against Trypanosoma equiperdum. | 2000 | Exp. Parasitol. | pmid:10910715 |
Ogura Y et al. | Chemoprevention of biliary carcinogenesis in syrian hamsters by the novel carboxamide derivative IS-741 after initiation with N-nitrosobis(2-oxopropyl)amine (BOP). | 2000 | Carcinogenesis | pmid:10910946 |
MalatyalioÄŸlu E et al. | Levels of stable metabolites of prostacyclin and thromboxane A2 and their ratio in normotensive and preeclamptic pregnant women during the antepartum and postpartum periods. | 2000 May-Jun | J Matern Fetal Med | pmid:10914626 |
Patrignani P et al. | Effects of vitamin E supplementation on F(2)-isoprostane and thromboxane biosynthesis in healthy cigarette smokers. | 2000 | Circulation | pmid:10920066 |
Dschietzig T et al. | Stimulation of pulmonary big endothelin-1 and endothelin-1 by antithrombin III: a rationale for combined application of antithrombin III and endothelin antagonists in sepsis-related acute respiratory distress syndrome? | 2000 | Crit. Care Med. | pmid:10921577 |
Muscará MN et al. | Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10924050 |
Wang JS et al. | Effect of strenuous arm exercise on oxidized-LDL-potentiated platelet activation in individuals with spinal cord injury. | 2000 | Thromb. Haemost. | pmid:10928481 |
Kamata K et al. | Altered endothelium-dependent and -independent hyperpolarization and endothelium-dependent relaxation in carotid arteries isolated from streptozotocin-induced diabetic rats. | 2000 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10935533 |
Kim WG et al. | Vasoconstrictive eicosanoid responses to extracorporeal circulation with or without an oxygenator in fetal lambs. | 2000 | Int J Artif Organs | pmid:10941636 |
Tsikas D et al. | Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine. | 2000 | J Chromatogr A | pmid:10941682 |
Porta C et al. | Amifostine, a reactive oxigen species scavenger with radiation- and chemo-protective properties, inhibits in vitro platelet activation induced by ADP, collagen or PAF. | 2000 | Haematologica | pmid:10942928 |
Sane S et al. | Eicosapentaenoic acid reduces pulmonary edema in endotoxemic rats. | 2000 | J. Surg. Res. | pmid:10945939 |