Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Waring P et al. | The effects of leukaemia inhibitory factor on platelet function. | 1993 | Br. J. Haematol. | pmid:8435339 |
Adatia I et al. | Abnormalities in the biosynthesis of thromboxane A2 and prostacyclin in children with cyanotic congenital heart disease. | 1993 | Br Heart J | pmid:8435245 |
Cole DJ et al. | Brain eicosanoid levels during temporary focal cerebral ischemia in rats: a microdialysis study. | 1993 | J Neurosurg Anesthesiol | pmid:8431669 |
Huttemeier PC et al. | Microdialysis measurements of PGD2, TXB2 and 6-KETO-PGF1 alpha in rat CA1 hippocampus during transient cerebral ischemia. | 1993 | Prostaglandins | pmid:8430228 |
Hata Y et al. | Primary colonic epithelial cell culture of the rabbit producing prostaglandins. | 1993 | Prostaglandins | pmid:8430223 |
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Blair IA et al. | Dietary modification of omega 6 fatty acid intake and its effect on urinary eicosanoid excretion. | 1993 | Am. J. Clin. Nutr. | pmid:8424383 |
Morin CL et al. | Thromboxane production in copper-deficient and marginal platelets: influence of superoxide dismutase and lipid hydroperoxides. | 1993 | Proc. Soc. Exp. Biol. Med. | pmid:8424106 |
Koudstaal PJ et al. | Increased thromboxane biosynthesis in patients with acute cerebral ischemia. | 1993 | Stroke | pmid:8421822 |
Van Assche FA et al. | Increased thromboxane formation in diabetic pregnancy as a possible contributor to preeclampsia. | 1993 | Am. J. Obstet. Gynecol. | pmid:8420355 |
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Feinberg WM and Bruck DC | Effect of oral nimodipine on platelet function. | 1993 | Stroke | pmid:8418530 |
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Hashimoto K et al. | Perfusion pressure control by adenosine triphosphate given during cardiopulmonary bypass. | 1993 | Ann. Thorac. Surg. | pmid:8417658 |
Koizumi T et al. | Effects of continuous infusion of nitroglycerin on pulmonary hemodynamics, lung lymph balance, and prostanoid products in the response to endotoxin in awake sheep. | 1993 | Lung | pmid:8416417 |
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Kramer HJ et al. | Effects of thromboxane A2 receptor blockade on oliguric ischemic acute renal failure in conscious rats. | 1993 | J. Am. Soc. Nephrol. | pmid:8400069 |
Cenni E et al. | Numerical and functional modifications in platelets induced by polyester coated by a hydrophilic polymer. | 1993 | Biomaterials | pmid:8399951 |
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Tönshoff B et al. | In vivo prostanoid formation during acute renal allograft rejection. | 1993 | Nephrol. Dial. Transplant. | pmid:8396748 |
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Kruse-Elliott KT and Olson NC | CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs. | 1993 | Am. J. Physiol. | pmid:8386479 |
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Noronha-Blob L et al. | NPC 15669, an inhibitor of neutrophil recruitment, is efficacious in acetic acid-induced colitis in rats. | 1993 | Gastroenterology | pmid:8385041 |
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Jones SA et al. | Eicosanoids in third ventricular cerebrospinal fluid of fetal and newborn sheep. | 1993 | Am. J. Physiol. | pmid:8381613 |
Arora RR et al. | Laser-induced stimulation of thromboxane B2 synthesis in human blood platelets: role of superoxide radicals. | 1993 | Am. Heart J. | pmid:8381256 |
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Ko FN et al. | CIS-19, a novel platelet activating factor receptor antagonist: in vitro and in vivo studies. | 1993 | Biochim. Biophys. Acta | pmid:8380343 |
Klimm JL et al. | Effects of free and macromolecular-bound TXA2 receptor antagonist BM 13.505 on U46619-induced platelet aggregation. | 1993 | Prostaglandins | pmid:8378540 |
Sullivan MH et al. | Effects of a thromboxane synthetase inhibitor on platelet function; possible risks of use in pregnancy. | 1993 | Prostaglandins | pmid:8378539 |
Chen TY et al. | Protective effects of E5, an antiendotoxin monoclonal antibody, in the ovine pulmonary circulation. | 1993 | J. Appl. Physiol. | pmid:8376269 |
Semrad SD et al. | Effect of tirilazad mesylate (U74006F) on eicosanoid and tumor necrosis factor generation in healthy and endotoxemic neonatal calves. | 1993 | Circ. Shock | pmid:8375024 |