Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kitano T et al. | Unwashed shed blood infusion causes deterioration in right ventricular function after coronary artery surgery. | 2000 | Anaesth Intensive Care | pmid:11153289 |
| Ferry DR et al. | A phase II study of the 5-lipoxygenase inhibitor, CV6504, in advanced pancreatic cancer: correlation of clinical data with pharmacokinetic and pharmacodynamic endpoints. | 2000 | Ann. Oncol. | pmid:11061613 |
| Ciabattoni G et al. | In vivo lipid peroxidation and platelet activation in cystic fibrosis. | 2000 | Am. J. Respir. Crit. Care Med. | pmid:11029317 |
| Zeng W and Zhang M | [Relationship between the alteration of 6-keto-PGF1 alpha and TXB2 in cervical mucus of patients with threatened preterm labor and the efficacy of magnesium sulfate treatment]. | 2000 | Hua Xi Yi Ke Da Xue Xue Bao | pmid:12501615 |
| Khan HH et al. | Plasma CPU-86017 concentrations regarding suppression of ouabain-induced cardiac arrhythmias and decrease of heart rate in guinea pigs. | 2000 | Acta Pharmacol. Sin. | pmid:11501061 |
| Wang W et al. | Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. | 2000 | Acta Pharmacol. Sin. | pmid:11501172 |
| Praticò D et al. | Endogenous biosynthesis of thromboxane and prostacyclin in 2 distinct murine models of atherosclerosis. | 2000 | Blood | pmid:11090066 |
| Boatman RJ et al. | Covalent protein adducts of hydroquinone in tissues from rats: quantitation of sulfhydryl-bound forms following single gavage or intraperitoneal administration or repetitive gavage administration. | 2000 | Chem. Res. Toxicol. | pmid:10995259 |
| Chou TC et al. | Mechanism of inhibition of platelet aggregation by HCL-31D. | 2000 | Eur. J. Pharmacol. | pmid:10650152 |
| Han G et al. | [Inhibitory effect of panicoin on platelet activation and its mechanism]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11789213 |
| Belton O et al. | Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. | 2000 | Circulation | pmid:10952950 |
| Jacobi KE et al. | Determination of eicosanoid and cytokine production in salvaged blood, stored red blood cell concentrates, and whole blood. | 2000 | J Clin Anesth | pmid:10818321 |
| Tanus-Santos JE et al. | Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. | 2000 | Eur. J. Pharmacol. | pmid:10822051 |
| Turpeinen AM et al. | Similar responses in hemostatic factors after consumption of wholemeal rye bread and low-fiber wheat bread. | 2000 | Eur J Clin Nutr | pmid:10822290 |
| Romano M et al. | Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide. | 2000 | J. Investig. Med. | pmid:10822898 |
| Sheu JR et al. | Mechanisms involved in the antiplatelet activity of Staphylococcus aureus lipoteichoic acid in human platelets. | 2000 | Thromb. Haemost. | pmid:10823277 |
| Zhou L et al. | [The effect of plasma from women with preeclampsia on endothelial cells activators in vitro]. | 2000 | Zhonghua Fu Chan Ke Za Zhi | pmid:11776183 |
| Nosál' R et al. | Chloroquine: a multipotent inhibitor of human platelets in vitro. | 2000 | Thromb. Res. | pmid:10828481 |
| Homoncik M et al. | Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100. | 2000 | Thromb. Haemost. | pmid:10739392 |
| Schweizer A et al. | Aprotinin does not impair renal haemodynamics and function after cardiac surgery. | 2000 | Br J Anaesth | pmid:10740541 |
| Rilantono LI et al. | Dietary antioxidative potential in arteries. | 2000 | Clin. Hemorheol. Microcirc. | pmid:11321428 |
| Sane S et al. | Eicosapentaenoic acid reduces pulmonary edema in endotoxemic rats. | 2000 | J. Surg. Res. | pmid:10945939 |
| Patrignani P et al. | Effects of vitamin E supplementation on F(2)-isoprostane and thromboxane biosynthesis in healthy cigarette smokers. | 2000 | Circulation | pmid:10920066 |
| De Somer F et al. | Phosphorylcholine coating of extracorporeal circuits provides natural protection against blood activation by the material surface. | 2000 | Eur J Cardiothorac Surg | pmid:11053824 |
| Naito Y et al. | Increase in blood pressure with enhanced Na+, K+ -ATPase activity in stroke-prone spontaneously hypertensive rats after 4-weeks intake of rapeseed oil as the sole dietary fat. | 2000 | Pharmacol. Toxicol. | pmid:11068856 |
| Van Hecken A et al. | Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers. | 2000 | J Clin Pharmacol | pmid:11028250 |
| Boyle JR et al. | Endovascular AAA repair attenuates the inflammatory and renal responses associated with conventional surgery. | 2000 | J. Endovasc. Ther. | pmid:11032254 |
| De La Cruz JP et al. | Antithrombotic potential of olive oil administration in rabbits with elevated cholesterol. | 2000 | Thromb. Res. | pmid:11113274 |
| Darlametsos IE et al. | Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: roles of the thromboxane and endothelin systems. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090252 |
| Cruz MA et al. | Vascular reactivity to angiotensin II and eicosanoid production in the human placenta from term and preterm pregnancy. | 2000 | Gynecol. Obstet. Invest. | pmid:11093047 |
| Kasahara M et al. | Effect of FK3311 on ischemia-reperfusion injury in canine pulmonary models. | 2000 | Transplant. Proc. | pmid:11120230 |
| De Jong A et al. | Antiphospholipid antibodies and platelets. | 2000 | Curr Rheumatol Rep | pmid:11123065 |
| Buccellati C et al. | Tramadol anti-inflammatory activity is not related to a direct inhibitory action on prostaglandin endoperoxide synthases. | 2000 | Eur J Pain | pmid:11124014 |
| Basu S et al. | Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity. | 2000 | Clin. Sci. | pmid:11099394 |
| Filipov NM et al. | Anti-inflammatory effects of ergotamine in steers. | 2000 | Proc. Soc. Exp. Biol. Med. | pmid:11044256 |
| Numminen H et al. | The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation. | 2000 | Stroke | pmid:10835443 |
| Delemarre FM et al. | Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11049696 |
| Kawasaki K et al. | Inhibition of 12(S)-hydroxyeicosatetraenoic acid (12-HETE) production suppressed the intimal hyperplasia caused by poor-runoff conditions in the rabbit autologous vein grafts. | 2000 | J. Cardiovasc. Pharmacol. | pmid:11065214 |
| Tsikas D et al. | Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine. | 2000 | J Chromatogr A | pmid:10941682 |
| Vazquez-Cruz B et al. | Increased renal vasoconstriction and gene expression of cyclooxygenase-1 in renovascular hypertension. | 2000 | J. Cardiovasc. Pharmacol. | pmid:11065217 |
| Greenberg HE et al. | A new cyclooxygenase-2 inhibitor, rofecoxib (VIOXX), did not alter the antiplatelet effects of low-dose aspirin in healthy volunteers. | 2000 | J Clin Pharmacol | pmid:11185674 |
| Siler-Khodr TM et al. | Effect of ethanol on thromboxane and prostacyclin production in the human placenta. | 2000 | Alcohol | pmid:10963940 |
| Laguna MS et al. | [Thromboxane B2 and platelet derived growth factor in essential thrombocythemia treated with anagrelide]. | 2000 | Medicina (B Aires) | pmid:11188949 |
| Matz RL et al. | Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids. | 2000 | Br. J. Pharmacol. | pmid:10991924 |
| Tanaka H et al. | Effects of milrinone on platelet aggregation in swine with pulmonary hypertension. | 2000 | J Crit Care | pmid:11011824 |
| Cracowski JL et al. | Human internal mammary artery contraction by isoprostaglandin f(2alpha) type-III [8-iso-prostaglandin F(2alpha)]. | 2000 | Eur. J. Pharmacol. | pmid:10844110 |
| Wang JS et al. | Effect of strenuous arm exercise on oxidized-LDL-potentiated platelet activation in individuals with spinal cord injury. | 2000 | Thromb. Haemost. | pmid:10928481 |
| Moosig F et al. | Opsonization of apoptotic neutrophils by anti-neutrophil cytoplasmic antibodies (ANCA) leads to enhanced uptake by macrophages and increased release of tumour necrosis factor-alpha (TNF-alpha). | 2000 | Clin. Exp. Immunol. | pmid:11122261 |
| Jacoby RF et al. | The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. | 2000 | Cancer Res. | pmid:11016626 |
| Ogura Y et al. | Chemoprevention of biliary carcinogenesis in syrian hamsters by the novel carboxamide derivative IS-741 after initiation with N-nitrosobis(2-oxopropyl)amine (BOP). | 2000 | Carcinogenesis | pmid:10910946 |
| Sugimoto KI et al. | Delayed hypotensive effect of the thromboxane A2/prostaglandin H2 receptor antagonist S-1452 in spontaneously hypertensive rats. | 2000 | Clin. Exp. Pharmacol. Physiol. | pmid:10901388 |
| Wang Z et al. | [Clinical and experimental study on treatment of bronchial asthma with pingchuan oral liquid]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938808 |
| Köfeler HC et al. | Effect of cytochrome P-450 inhibitors econazole, bifonazole and clotrimazole on prostanoid formation. | 2000 | Br. J. Pharmacol. | pmid:10903961 |
| Yu K et al. | [Clinical observation on treatment of pediatric intractable nephropathy with modified taohong siwu decoction]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938829 |
| Toft G et al. | Intravenously and topically applied magnesium in the prevention of arterial thrombosis. | 2000 | Thromb. Res. | pmid:10904104 |
| Shi X et al. | [Effects of Salvia miltiorrhiza compound injection on serum endothelin, prostaglandin I2/thromboxane A2 ratio alteration following myocardial ischemia-reperfusion in patients undergoing intracardiac surgery]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938858 |
| Giedrojć J et al. | [Investigation of prostaglandins in supernatant of cultured monocytes]. | 2000 | Prz. Lek. | pmid:10907365 |
| Miao X et al. | [Effect of yinchen dandao decoction on plasma fibronectin, biliary thromboxane A2 and prostaglandin I2 in human and animal suffering from acute cholangitis]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938860 |
| Momi S et al. | Involvement of platelets in experimental mouse trypanosomiasis: evidence of mouse platelet cytotoxicity against Trypanosoma equiperdum. | 2000 | Exp. Parasitol. | pmid:10910715 |
| Moon CH et al. | Mechanism for antiplatelet effect of onion: AA release inhibition, thromboxane A(2)synthase inhibition and TXA(2)/PGH(2)receptor blockade. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883058 |
| Lasserre B et al. | Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883059 |
| Arakida Y et al. | Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs. | 2000 | Eur. J. Pharmacol. | pmid:10969159 |
| Bereczki C et al. | The roles of platelet function, thromboxane, blood lipids and nitric oxide in hypertension of children and adolescents. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883060 |
| Carty E et al. | Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848666 |
| Dschietzig T et al. | Stimulation of pulmonary big endothelin-1 and endothelin-1 by antithrombin III: a rationale for combined application of antithrombin III and endothelin antagonists in sepsis-related acute respiratory distress syndrome? | 2000 | Crit. Care Med. | pmid:10921577 |
| Muscará MN et al. | Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10924050 |
| Mizugaki M | [Microdetermination of eicosanoids using mass spectrometry]. | 2000 | Nippon Yakurigaku Zasshi | pmid:10876809 |
| Depré M et al. | Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans. | 2000 | Eur. J. Clin. Pharmacol. | pmid:10877012 |
| Theriot JA et al. | Dietary chloride does not correlate with urinary thromboxane in deoxycorticosterone acetate-treated rats. | 2000 | J. Lab. Clin. Med. | pmid:10850649 |
| Suzuki N et al. | Difference in urinary LTE4 and 11-dehydro-TXB2 excretion in asthmatic patients. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:11060902 |
| Jacobi K et al. | Plasma levels of eicosanoids after transfusion of intraoperatively salvaged blood. | 2000 | Vox Sang. | pmid:10729809 |
| Rioja I et al. | An anti-inflammatory ditriazine inhibiting leukocyte functions and expression of inducible nitric oxide synthase and cyclo-oxygenase-2. | 2000 | Eur. J. Pharmacol. | pmid:10844115 |
| Tran HS et al. | The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock. | 2000 | Shock | pmid:10847636 |
| Maccarrone M et al. | Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833416 |
| Gardan B et al. | Vasoconstrictor effects of iso-prostaglandin F2alpha type-III (8-iso-prostaglandin F2alpha) on human saphenous veins. | 2000 | J. Cardiovasc. Pharmacol. | pmid:10813374 |
| Suntres ZE and Shek PN | Prophylaxis against lipopolysaccharide-induced lung injuries by liposome-entrapped dexamethasone in rats. | 2000 | Biochem. Pharmacol. | pmid:10704946 |
| Cryer B et al. | Effects of cutaneous aspirin on the human stomach and duodenum. | 1999 Sep-Oct | Proc. Assoc. Am. Physicians | pmid:10519166 |
| Stewart KG et al. | Estrogen decreases prostaglandin H synthase products from endothelial cells. | 1999 Nov-Dec | J. Soc. Gynecol. Investig. | pmid:10643586 |
| Tong H et al. | Prostaglandin endoperoxide synthase-2 abundance is increased in brain tissues of late-gestation fetal sheep in response to cerebral hypoperfusion. | 1999 May-Jun | J. Soc. Gynecol. Investig. | pmid:10376268 |
| Uriu K et al. | Effect of acute thromboxane A2 inhibition on the renal hemodynamics in a spontaneously non-insulin-dependent diabetic rat, Otsuka Long-Evans Tokushima Fatty rat. | 1999 Jul-Aug | J. Diabetes Complicat. | pmid:10616856 |
| Pestana M et al. | Kidney graft-infiltrating cells synthesize significantly higher amounts of prostaglandin E2 pre and during acute rejection. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083119 |
| van den Dorpel MA et al. | Beneficial effects of conversion from cyclosporine to azathioprine on fibrinolysis in renal transplant recipients. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083130 |
| Tanaka H et al. | Leukotriene (LT)-receptor antagonist is more effective in asthmatic patients with a low baseline ratio of urinary LTE4 to 2,3-dinor-6-keto-prostaglandin (PG)F1alpha. | 1999 | Allergy | pmid:10380781 |
| Vijaya Kumar M et al. | The anhydrous milk fat, ghee, lowers serum prostaglandins and secretion of leukotrienes by rat peritoneal macrophages. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10574649 |
| De La Cruz JP et al. | Antiplatelet effect of the anaesthetic drug propofol: influence of red blood cells and leucocytes. | 1999 | Br. J. Pharmacol. | pmid:10602334 |
| Ferro D et al. | Determinants of enhanced thromboxane biosynthesis in patients with systemic lupus erythematosus. | 1999 | Arthritis Rheum. | pmid:10616019 |
| Lees P et al. | A pharmacodynamic and pharmacokinetic study with vedaprofen in an equine model of acute nonimmune inflammation. | 1999 | J. Vet. Pharmacol. Ther. | pmid:10372594 |
| Giuliano F and Warner TD | Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs. | 1999 | Br. J. Pharmacol. | pmid:10372826 |
| Morrow JD et al. | Increased formation of thromboxane in vivo in humans with mastocytosis. | 1999 | J. Invest. Dermatol. | pmid:10417625 |
| Mizugaki M et al. | Monitoring of the thromboxane A2/prostacyclin ratio in the urine of patients with retinal vascular occlusion through the low-dose-aspirin therapy using the gas chromatography/selected ion monitoring method. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10593167 |
| Hishinuma T et al. | Urinary thromboxane A2/prostacyclin balance reflects the pathological state of a diabetic. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10593168 |
| Hoch B and Bernhard M | Reduced prostacyclin to thromboxane A2 ratio is correlated with central apneas in preterm infants. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10593170 |
| Gonchar M et al. | Kinetics of prostanoid synthesis by macrophages is regulated by arachidonic acid sources. | 1999 | Eur. J. Biochem. | pmid:10504410 |
| van Genderen PJ et al. | Thromboxane-dependent platelet activation in vivo precedes arterial thrombosis in thrombocythaemia: a rationale for the use of low-dose aspirin as an antithrombotic agent. | 1999 | Br. J. Haematol. | pmid:10086775 |
| Andrieu S et al. | Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs. | 1999 | J. Cardiovasc. Pharmacol. | pmid:10028935 |
| Pirich C et al. | Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. | 1999 | Thromb. Res. | pmid:10588465 |
| Ricetti MM et al. | Effects of sodium selenite on in vitro interactions between platelets and endothelial cells. | 1999 | Int. J. Clin. Lab. Res. | pmid:10436266 |
| Tsugawa K et al. | A selective cyclo-oxygenase-2 inhibitor, NS-398, may improve portal hypertension without inducing gastric mucosal injury. | 1999 | J. Gastroenterol. Hepatol. | pmid:10440208 |
| Zhang S et al. | Effects of acupuncture on the levels of endothelin, TXB2, and 6-keto-PGF1 alpha in apoplexy patients. | 1999 | J Tradit Chin Med | pmid:10453582 |
| Arakida Y et al. | Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10454505 |