Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Wang S and Zhu G | [Effects of Codonopsis pilosulae on the synthesis of thromboxane A2 and prostacyclin]. | 1990 | Zhong Xi Yi Jie He Za Zhi | pmid:2208415 |
Yu Z and Chen KJ | [Effect of chuan-xiong granules on platelet aggregation, plasma beta-thromboglobulin, platelet factor IV, thromboxane B2 and 6-keto-prostaglandin F1 alpha in coronary disease patients]. | 1987 | Zhong Xi Yi Jie He Za Zhi | pmid:2954711 |
Liu Z | [Effects of Ligusticum wallichii on the plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2 and 6-keto-PGF1 alpha in rabbits under acute experimental cerebral ischemia]. | 1990 | Zhong Xi Yi Jie He Za Zhi | pmid:2148509 |
Xu QY and Jia BS | [Relation between plasma thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and traditional Chinese medicine in different types of ischemic heart disease patients]. | 1987 | Zhong Xi Yi Jie He Za Zhi | pmid:3594705 |
Dong G | [Relation of pale tongue, purple tongue and TXA2-PGI2 regulation system]. | 1990 | Zhong Xi Yi Jie He Za Zhi | pmid:2401034 |
Wang CB and Chang AM | [Plasma thromboxane B2 changes in severe icteric hepatitis treated by traditional Chinese medicine--dispelling the pathogenic heat from blood, promoting blood circulation and administrating large doses of radix Paeoniae--a report of 6 cases]. | 1985 | Zhong Xi Yi Jie He Za Zhi | pmid:3161645 |
Xu XY and Wang Q | [The influence of sodium ferulate on hypotensive effect and urinary excretion of TXB2 after captopril in essential hypertensive patients]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:1667512 |
Liu Z | [Effects of Ligusticum wallichii on the plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2 and 6-keto-PGF1 alpha in patients with acute cerebral infarction]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:1840363 |
Lin ZX et al. | [Relation between malondialdehyde generation by platelets and plasma thromboxane B2 and diagnostic classification by syndrome differentiation of traditional Chinese medicine in stroke during acute stage]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:1821334 |
Zhang J et al. | [Isolation of resisting thrombus and arteriosclerosis compounds in leaves of Salix matsudana]. | 1999 | Zhong Yao Cai | pmid:12575095 |
Xu L et al. | [Effects of effective component from "qing kai ling" on endothelial cell of microvessel in MCAO rats]. | 2004 | Zhong Yao Cai | pmid:15376390 |
Wei X et al. | [Study of dahuangzhechong pills on anti-arterial thrombosis with the orthogonal design]. | 2012 | Zhong Yao Cai | pmid:22734422 |
Li JS et al. | [Change in intestinal free radical and prostaglandin metabolism in the aged rats with pneumococcus pneumonia]. | 2003 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:14552688 |
Yin M et al. | [Experimental study of effects of cyclooxygenase-2 inhibitor on apoptosis of hypoxic myocardial cells in vitro]. | 2006 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:16647015 |
Sha JP et al. | [Effect of the recombinant staphylokinase on pancreatic ischemia in severe acute pancreatitis of rats]. | 2007 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:17708840 |
Shen ZQ et al. | Inhibitory effects of copper-aspirin complex on platelet aggregation. | 1997 | Zhongguo Yao Li Xue Bao | pmid:10072923 |
Zeng S and Guo ZG | Mepyramine inhibits platelet activating factor-induced rabbit platelet aggregation: role of intracellular histamine. | 1997 | Zhongguo Yao Li Xue Bao | pmid:10072970 |
Sun XM et al. | [Effect of 2-naphthyl-3- (3,4-dimethoxy) phenyl-propenoic acid on the metabolism of arachidonic acid in rabbit platelets]. | 1990 | Zhongguo Yao Li Xue Bao | pmid:2403015 |
Chen XS et al. | Effects of CI-930, a novel phosphodiesterase III inhibitor, on platelet aggregation and arachidonic acid metabolism. | 1990 | Zhongguo Yao Li Xue Bao | pmid:1966575 |
Huang CG et al. | [Effects of berberine on synthesis of platelet TXA2 and plasma PGI2 in rabbits]. | 1991 | Zhongguo Yao Li Xue Bao | pmid:1824005 |