Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Asthma D001249 52 associated lipids
Kidney Diseases D007674 29 associated lipids
Femoral Fractures D005264 7 associated lipids
Weight Gain D015430 101 associated lipids
Hyperemia D006940 25 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Ulcer D014456 16 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Endometriosis D004715 29 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Myocardial Infarction D009203 21 associated lipids
Proteinuria D011507 30 associated lipids
Arteriosclerosis D001161 86 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Fibrosis D005355 23 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Fetal Diseases D005315 8 associated lipids
Glomerulonephritis D005921 35 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Sepsis D018805 11 associated lipids
Leukopenia D007970 9 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Stroke D020521 32 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Brain Ischemia D002545 89 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Seizures D012640 87 associated lipids
Peptic Ulcer D010437 19 associated lipids
Birth Weight D001724 23 associated lipids
Hypertension D006973 115 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Thromboembolism D013923 6 associated lipids
Nasal Polyps D009298 26 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Olson MT et al. Effect of assay specificity on the association of urine 11-dehydro thromboxane B2 determination with cardiovascular risk. 2012 J. Thromb. Haemost. pmid:23072449
Alizzi AM et al. Reduction of post-surgical pericardial adhesions using a pig model. 2012 Heart Lung Circ pmid:22078313
Hui C et al. Changes in coagulation and hemodynamics during pregnancy: a prospective longitudinal study of 58 cases. 2012 Arch. Gynecol. Obstet. pmid:22083312
Hu YY et al. Six alkaloids inhibit secretion of IL-1α, TXB(2), ET-1 and E-selectin in LPS-induced endothelial cells. 2012 Immunol. Invest. pmid:22087636
Shoeb M and Ramana KV Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages. 2012 Free Radic. Biol. Med. pmid:22067901
Li C et al. Reversal of the anti-platelet effects of aspirin and clopidogrel. 2012 J. Thromb. Haemost. pmid:22268852
Rodríguez-Vilarrupla A et al. PPARα activation improves endothelial dysfunction and reduces fibrosis and portal pressure in cirrhotic rats. 2012 J. Hepatol. pmid:22245887
Mullins KB et al. Effects of carprofen, meloxicam and deracoxib on platelet function in dogs. 2012 Vet Anaesth Analg pmid:22248445
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Mo J et al. Expression of interleukin-18 in a rat model of deep vein thrombosis. 2012 J Cardiovasc Surg (Torino) pmid:22318348
Hartanto MD et al. Urinary 11-dehydro-thromboxane B₂ and 2,3-dinor-6-keto-prostaglandin-F₁α in healthy post-menopausal and pre-menopausal women receiving aspirin 100 mg. 2012 J. Thromb. Thrombolysis pmid:22311294
Ajamieh H et al. Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation. 2012 J. Gastroenterol. Hepatol. pmid:22432744
Shatoor AS et al. Effect of Hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino Wistar rats. 2012 Thromb. Res. pmid:22261477
Brentnall C et al. Potency and selectivity of carprofen enantiomers for inhibition of bovine cyclooxygenase in whole blood assays. 2012 Res. Vet. Sci. pmid:22703724
Peters SM et al. In vivo characterization of inflammatory biomarkers in swine and the impact of flunixin meglumine administration. 2012 Vet. Immunol. Immunopathol. pmid:22648045
Zhou MT et al. Continuous regional arterial infusion with fluorouracil and octreotide attenuates severe acute pancreatitis in a canine model. 2012 PLoS ONE pmid:22655040
Saadawi S et al. Inhibitory effects of acetylmelodorinol, chrysin and polycarpol from Mitrella kentii on prostaglandin Eâ‚‚ and Thromboxane Bâ‚‚ production and platelet activating factor receptor binding. 2012 Molecules pmid:22538486
Yokoyama H et al. Theoretical investigation of aspirin dosage regimen to exhibit optimal antiplatelet effects and decrease risk of upper gastrointestinal lesions. 2012 Biol. Pharm. Bull. pmid:23047244
Liou JT et al. Levobupivacaine differentially suppresses platelet aggregation by modulating calcium release in a dose-dependent manner. 2012 Acta Anaesthesiol Taiwan pmid:23026170