Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Asthma D001249 52 associated lipids
Kidney Diseases D007674 29 associated lipids
Femoral Fractures D005264 7 associated lipids
Weight Gain D015430 101 associated lipids
Hyperemia D006940 25 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Ulcer D014456 16 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Endometriosis D004715 29 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Myocardial Infarction D009203 21 associated lipids
Proteinuria D011507 30 associated lipids
Arteriosclerosis D001161 86 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Fibrosis D005355 23 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Fetal Diseases D005315 8 associated lipids
Glomerulonephritis D005921 35 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Sepsis D018805 11 associated lipids
Leukopenia D007970 9 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Stroke D020521 32 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Brain Ischemia D002545 89 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Seizures D012640 87 associated lipids
Peptic Ulcer D010437 19 associated lipids
Birth Weight D001724 23 associated lipids
Hypertension D006973 115 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Thromboembolism D013923 6 associated lipids
Nasal Polyps D009298 26 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Nørregaard R et al. Urinary tract obstruction induces transient accumulation of COX-2-derived prostanoids in kidney tissue. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20147610
Derhaschnig U et al. Effects of aspirin and NO-aspirin (NCX 4016) on platelet function and coagulation in human endotoxemia. 2010 Platelets pmid:20608787
Cheng Y and Li ZK [Changes of neurotransmitter endothelin, thromboxance B2 and 6-keto-prostaglandin F1 alpha in patients with chronic pulmonary heart disease]. 2010 Nan Fang Yi Ke Da Xue Xue Bao pmid:20584647
Boutaud O and Oates JA Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes. 2010 Methods Mol. Biol. pmid:20645166
Kawaguchi T et al. The human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor. 2010 Cell Biol. Int. pmid:20522022
Oldenhof J et al. Effect of maximum OTC doses of naproxen sodium or acetaminophen on low-dose aspirin inhibition of serum thromboxane B2. 2010 Curr Med Res Opin pmid:20429831
Parmar JH et al. Significant prostacyclin/thromboxane level imbalance after lower limb arterial angioplasty: a possible platelet function alteration. 2010 J Vasc Interv Radiol pmid:20800778
Warner JH et al. Adaptive regression modeling of biomarkers of potential harm in a population of U.S. adult cigarette smokers and nonsmokers. 2010 BMC Med Res Methodol pmid:20233412
Hepgül G et al. Preventive effect of pentoxifylline on acute radiation damage via antioxidant and anti-inflammatory pathways. 2010 Dig. Dis. Sci. pmid:19294507
Iwasaki W et al. Changes in the fatty acid composition of the liver with the administration of N-3 polyunsaturated fatty acids and the effects on warm ischemia/reperfusion injury in the rat liver. 2010 Shock pmid:19543146
Yen PL et al. Effects of deep-frying oil on blood pressure and oxidative stress in spontaneously hypertensive and normotensive rats. 2010 Nutrition pmid:19592221
Huntjens DR et al. Impact of chronic inflammation on the pharmacokinetic-pharmacodynamic relationship of naproxen. 2010 Eur J Pain pmid:19679500
Santilli F et al. Postprandial hyperglycemia is a determinant of platelet activation in early type 2 diabetes mellitus. 2010 J. Thromb. Haemost. pmid:20088941
Addad F et al. Response variability to aspirin and one-year prediction of vascular events in patients with stable coronary artery disease. 2010 J. Thromb. Thrombolysis pmid:19381450
Dołegowska B et al. Dynamics of thromboxane level changes during early phase of allograft reperfusion. 2009 Sep-Oct Clin Transplant pmid:19298388
Tantry US et al. Aspirin resistance. 2009 Sep-Oct Prog Cardiovasc Dis pmid:19732606
Thomson VS et al. Aspirin resistance in Indian patients with coronary artery disease and cardiovascular events. 2009 Oct-Dec J Postgrad Med pmid:20083870
Goodman L et al. Effects of firocoxib and tepoxalin on healing in a canine gastric mucosal injury model. 2009 Jan-Feb J. Vet. Intern. Med. pmid:19175721
Capodanno D and Angiolillo DJ Platelet monitoring for PCI: which test is the one to choose? 2009 Hamostaseologie pmid:19882078
Gao XR et al. Efficacy of different doses of aspirin in decreasing blood levels of inflammatory markers in patients with cardiovascular metabolic syndrome. 2009 J. Pharm. Pharmacol. pmid:19903376
Zuo Y et al. Gross-total hematoma removal of hypertensive basal ganglia hemorrhages: a long-term follow-up. 2009 J. Neurol. Sci. pmid:19801153
Frelinger AL et al. Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization. 2009 Circulation pmid:19996015
Guerrero MD et al. Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression. 2009 Eur. J. Pharmacol. pmid:19686718
Dietrich-Muszalska A and Olas B Isoprostenes as indicators of oxidative stress in schizophrenia. 2009 World J. Biol. Psychiatry pmid:19673085
Lowe FJ et al. Evaluation of biomarkers of exposure and potential harm in smokers, former smokers and never-smokers. 2009 Clin. Chem. Lab. Med. pmid:19676143
Stanke-Labesque F et al. Increased urinary leukotriene E4 excretion in obstructive sleep apnea: effects of obesity and hypoxia. 2009 J. Allergy Clin. Immunol. pmid:19596146
Huntjens DR et al. Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors. 2009 Eur J Pain pmid:18774319
Correa JA et al. Virgin olive oil polyphenol hydroxytyrosol acetate inhibits in vitro platelet aggregation in human whole blood: comparison with hydroxytyrosol and acetylsalicylic acid. 2009 Br. J. Nutr. pmid:18775097
Hynninen VV et al. Oral voriconazole and miconazole oral gel produce comparable effects on the pharmacokinetics and pharmacodynamics of etoricoxib. 2009 Eur. J. Clin. Pharmacol. pmid:18777173
Muir AR et al. Assessment of aspirin resistance varies on a temporal basis in patients with ischaemic heart disease. 2009 Heart pmid:18697805
Foudi N et al. Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation. 2009 Cardiovasc. Res. pmid:18952694
Rogers LK et al. Differential responses in the lungs of newborn mouse pups exposed to 85% or >95% oxygen. 2009 Pediatr. Res. pmid:18703992
Fernández-Arche A et al. Long-chain fatty alcohols from pomace olive oil modulate the release of proinflammatory mediators. 2009 J. Nutr. Biochem. pmid:18555679
Zeng HH et al. [Effect of safflower injection on pulmonary hypertension in rat during chronic hypoxia and hypercapnia]. 2009 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:21186611
Guagnano MT et al. Determinants of platelet activation in hypertensives with microalbuminuria. 2009 Free Radic. Biol. Med. pmid:19280705
Lo HM et al. 2'-Ethoxy-5'-methoxy-2-(5-methylthienyl)chalcone inhibits collagen-induced protein tyrosine phosphorylation and thromboxane formation during platelet aggregation and adhesion. 2009 Pharmacology pmid:19690443
Struthmann L et al. Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo. 2009 J. Thromb. Haemost. pmid:19691487
Omura Y et al. Severe asthma with markedly increased asbestos of 2 types & TXB2, and markedly reduced acetylcholine, DHEA & drug uptake in parts of upper lungs, & similar abnormalities at respiratory & cardiac center of medulla oblongata: complete elimination of this asthma within 15 days using one optimal dose of astragalus & application of strong red light & EMF neutralizer on respiratory centers of abnormal medulla oblongata. 2009 Acupunct Electrother Res pmid:19711774
Sobotková A et al. Antioxidants change platelet responses to various stimulating events. 2009 Free Radic. Biol. Med. pmid:19766712
Shen H et al. Aspirin Resistance in healthy drug-naive men versus women (from the Heredity and Phenotype Intervention Heart Study). 2009 Am. J. Cardiol. pmid:19660620
Leoncini G et al. In retinal vein occlusion platelet response to thrombin is increased. 2009 Thromb. Res. pmid:19660790
Canales A et al. Platelet aggregation, eicosanoid production and thrombogenic ratio in individuals at high cardiovascular risk consuming meat enriched in walnut paste. A crossover, placebo-controlled study. 2009 Br. J. Nutr. pmid:19068151
Duda MK et al. Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction. 2009 Cardiovasc. Res. pmid:19015135
Hynninen VV et al. Voriconazole increases while itraconazole decreases plasma meloxicam concentrations. 2009 Antimicrob. Agents Chemother. pmid:19015346
Kerola M et al. Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo. 2009 Basic Clin. Pharmacol. Toxicol. pmid:19152549
Lauring B et al. Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects. 2009 J Clin Pharmacol pmid:19833861
O'Donnell ME et al. The effects of cilostazol on exercise-induced ischaemia-reperfusion injury in patients with peripheral arterial disease. 2009 Eur J Vasc Endovasc Surg pmid:19112032
Bailey SR et al. Plasma concentrations of endotoxin and platelet activation in the developmental stage of oligofructose-induced laminitis. 2009 Vet. Immunol. Immunopathol. pmid:19091426
Li L et al. The anti-inflammatory effects of ZLJ-6, a novel dual cyclooxygenase/5-lipoxygenase inhibitor. 2009 Eur. J. Pharmacol. pmid:19243697
Li H et al. [Effect of an integrative medical regimen on levels of vascular endothelial function and hypersensitive C-reactive protein in elderly patients with isolated systolic hypertension]. 2009 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:19382469