Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Thromboxane b2?

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What functions are associated with Thromboxane b2?


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What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

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All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Simmons PM et al. The release of leukotriene B4 during experimental inflammation. 1983 Biochem. Pharmacol. pmid:6305369
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Hidaka T et al. Thromboxane formation from arachidonic acid and prostaglandin H2 in rabbit spleen. 1983 J. Biochem. pmid:6404897
Wilson L Effects of estradiol and progesterone on uterine prostaglandin levels in the pregnant rat. 1983 Prostaglandins pmid:6635211
Sanders TA and Hochland MC A comparison of the influence on plasma lipids and platelet function of supplements of omega 3 and omega 6 polyunsaturated fatty acids. 1983 Br. J. Nutr. pmid:6639916
Mehta JL Prostaglandins: regulatory role in cardiovascular system and implications in ischemic heart disease. 1983 Int. J. Cardiol. pmid:6642760
Mathieson MA et al. Ischemia of the limb stimulates thromboxane production and myocardial depression. 1983 Surg Gynecol Obstet pmid:6648769
Barrett PA and Butler KD Shortening of platelet survival by induced hypercholesterolaemia in rabbits and its prolongation by anagrelide. 1983 Thromb. Haemost. pmid:6648889
Robinson C and Hoult JR Thromboxane A2 analogues inhibit the metabolism of thromboxane B2 in perfused guinea-pig lung. 1983 Biochim. Biophys. Acta pmid:6652102
Socini A et al. Fish oil administration as a supplement to a corn oil containing diet affects arterial prostacyclin production more than platelet thromboxane formation in the rat. 1983 Prostaglandins pmid:6310702
Gethmann U et al. Effect of catecholestrogens on prostaglandin release by rat pituitaries superfused in vitro. 1983 Arch. Gynecol. pmid:6320749
Patel K and Bakhle YS Thromboxane B2 (TxB2) metabolism in rat isolated lung and its inhibition by drugs. 1983 Prostaglandins Leukot Med pmid:6573689
Davì G et al. Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients. 1983 Prostaglandins Leukot Med pmid:6573692
Lieb J et al. Elevated levels of prostaglandin E2 and thromboxane B2 in depression. 1983 Prostaglandins Leukot Med pmid:6574523
Okahara T et al. Zonal heterogeneity of prostaglandin and thromboxane release in the dog kidney. 1983 Prostaglandins pmid:6575405
Coceani F et al. Prostaglandin E2 and thromboxane B2 in cerebrospinal fluid of afebrile and febrile cat. 1983 Am. J. Physiol. pmid:6574712
Viinikka L et al. Effect of prolonged treatment with acetylsalicylic acid and dipyridamole on platelet thromboxane A2 production in atherosclerotic subjects. 1983 Prostaglandins Leukot Med pmid:6576385
Fukumoto S and Tanaka K Protective effects of thromboxane A2 synthetase inhibitors on endotoxin shock. 1983 Prostaglandins Leukot Med pmid:6576388
Roy L et al. Increased plasma concentrations of prostacyclin metabolite 6-keto-PGF1 alpha in essential hypertension. Influence of therapy with labetalol. 1983 Am. J. Cardiol. pmid:6823861
Butler RR et al. Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production. 1983 J. Pharmacol. Exp. Ther. pmid:6339712
Asbóth G et al. Conversion of arachidonic acid to prostanoids in the avian uterus. 1983 Biochim. Biophys. Acta pmid:6402032