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Effects of d-003, a new substance purified from sugar cane wax, on platelet aggregation and plasma levels of arachidonic acid metabolites in healthy volunteers. |
2004 |
Int J Clin Pharmacol Res |
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Effect of red clover isoflavones on cox-2 activity in murine and human monocyte/macrophage cells. |
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Nutr Cancer |
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Circulation |
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Co-administration of nitric oxide-aspirin (NCX-4016) and aspirin prevents platelet and monocyte activation and protects against gastric damage induced by aspirin in humans. |
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Meloxicam does not affect the antiplatelet effect of aspirin in healthy male and female volunteers. |
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J Clin Pharmacol |
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Short-term prevention of thromboembolic complications in patients with atrial fibrillation with aspirin plus clopidogrel: the Clopidogrel-Aspirin Atrial Fibrillation (CLAAF) pilot study. |
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[Some mechanisms of the development of endothelial disfunction in aging]. |
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Acetaldehyde induces histamine release from human airway mast cells to cause bronchoconstriction. |
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Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs. |
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J. Pharm. Pharmacol. |
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The effect of general anesthesia and abdominal surgery upon plasma thromboxane B concentrations in horses. |
2004 |
Vet Anaesth Analg |
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Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators. |
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Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism. |
2004 |
J. Pharmacol. Exp. Ther. |
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Argan (Argania spinosa) oil lowers blood pressure and improves endothelial dysfunction in spontaneously hypertensive rats. |
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Br. J. Nutr. |
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[Dynamic changes of plasma levels of prostacycline and thromboxane A2 and their correlation with the severity of hepatic injury in rats with nonalcoholic fatty liver disease]. |
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Arthritis Rheum. |
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Regulation of Candida albicans morphogenesis by fatty acid metabolites. |
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Infect. Immun. |
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Modulation of the expression and activity of cyclooxygenases in normal and accelerated erythropoiesis. |
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Exp. Hematol. |
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Low concentration of oxidized low density lipoprotein suppresses platelet reactivity in vitro: an intracellular study. |
2004 |
Lipids |
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The effects of a selective cyclooxygenase-2 inhibitor on small bowel ischemia-reperfusion injury. |
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Hepatogastroenterology |
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Effects of cyclooxygenases inhibitors on vasoactive prostanoids and thrombin generation at the site of microvascular injury in healthy men. |
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The COX-2 selective inhibitor, valdecoxib, does not impair platelet function in the elderly: results of a randomized controlled trial. |
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J Clin Pharmacol |
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Heterogeneity of microvascular endothelial cells isolated from human term placenta and macrovascular umbilical vein endothelial cells. |
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Eur. J. Cell Biol. |
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Synergistic effect of D-003 and aspirin on experimental thrombosis models. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
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Prostacyclin/thromboxane early changes in pregnancies that are complicated by preeclampsia. |
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Am. J. Obstet. Gynecol. |
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Pharmacological evaluation of the novel thromboxane modulator BM-567 (I/II). Effects of BM-567 on platelet function. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12538090
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High dose of inhaled fluticasone reduces high levels of urinary leukotriene E4 in the early morning in mild and moderate nocturnal asthma. |
2003 |
Chest |
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Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate. |
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Biochem. Pharmacol. |
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Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats. |
2003 |
Naunyn Schmiedebergs Arch. Pharmacol. |
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Changes in cerebral microcirculation during and after abdominal aortic cross-clamping in rabbits: the role of thromboxane A2 receptor. |
2003 |
Anesth. Analg. |
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Thromboxane synthesis is increased by upregulation of cytosolic phospholipase A2 and cyclooxygenase-2 in peripheral polymorphonuclear leukocytes during bacterial infection in childhood. |
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Am. J. Hematol. |
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Influences of prostanoids and nitric oxide on post-suspension hypotension in female Sprague-Dawley rats. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
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Evidence for a role for Galphai1 in mediating weak agonist-induced platelet aggregation in human platelets: reduced Galphai1 expression and defective Gi signaling in the platelets of a patient with a chronic bleeding disorder. |
2003 |
Blood |
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Antenatal administration of celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, appears to improve placental perfusion in the pregnant rabbit. |
2003 |
Prostaglandins Other Lipid Mediat. |
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F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins. |
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Nat. Med. |
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Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study. |
2003 |
Gastroenterology |
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Chiral 3,3'-(1,2-ethanediyl)-bis[2-(3,4-dimethoxyphenyl)-4-thiazolidinones] with anti-inflammatory activity. Part 11: evaluation of COX-2 selectivity and modelling. |
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Bioorg. Med. Chem. |
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The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
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Comparison of nasal and oral inhalation during exhaled breath condensate collection. |
2003 |
Am. J. Respir. Crit. Care Med. |
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Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain. |
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J. Neurochem. |
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One-lung ventilation with high tidal volumes and zero positive end-expiratory pressure is injurious in the isolated rabbit lung model. |
2003 |
Anesth. Analg. |
pmid:12505956
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Complement activation during hemorrhagic shock and resuscitation in swine. |
2003 |
Shock |
pmid:14501949
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Effects of exercise on platelet and aortic functions in aged rats. |
2003 |
Acta Physiol. Scand. |
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Histone H1 modulates immune status in experimental breast cancer. |
2003 |
Chemotherapy |
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Tissue chamber model of acute inflammation in farm animal species. |
2003 |
Res. Vet. Sci. |
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Antioxidant therapy with Salvia miltiorrhiza decreases plasma endothelin-1 and thromboxane B2 after cardiopulmonary bypass in patients with congenital heart disease. |
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J. Thorac. Cardiovasc. Surg. |
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Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats. |
2003 |
Eur. J. Pharmacol. |
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Daily prickly pear consumption improves platelet function. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12878452
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Role of thromboxane in producing portal hypertension following trauma-hemorrhage. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Chronic hypoxia attenuates ischemia-reperfusion-induced increase in pulmonary vascular resistance. |
2003 |
Life Sci. |
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[Effect of aspirin combined with perindopril on prostacyclin, thromboxone A2, and norepinephrine in the blood of arteriosclerosis rabbit models and the cardiac function]. |
2003 |
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[Protective effect of selective cyclooxygenase-2 inhibitor on alcohol-induced liver injury in rats]. |
2003 |
Zhonghua Gan Zang Bing Za Zhi |
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Effects of phenacetin and its metabolite p-phenetidine on COX-1 and COX-2 activities and expression in vitro. |
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Thromb. Res. |
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Clusterin protects the lung from leukocyte-induced injury. |
2003 |
Shock |
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Inflammation is involved in the organ damage induced by sinoaortic denervation in rats. |
2003 |
J. Hypertens. |
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The role of inflammatory mediators in severe acute pancreatitis and regulation of glucocorticoids. |
2003 |
HBPD INT |
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Conjugated linoleic acids lower the release of eicosanoids and nitric oxide from human aortic endothelial cells. |
2003 |
J. Nutr. |
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Propofol does not induce pulmonary dysfunction in stressed endotoxic pigs receiving Intralipid. |
2003 |
Crit. Care Med. |
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Platelet aggregation, thromboxane production and thrombogenic ratio in postmenopausal women consuming high oleic acid-sunflower oil or palmolein. |
2003 |
Eur J Nutr |
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[Correlation between TXB2, 6-Keto-PGF1alpha and liver metastasis in rats model with blood stasis]. |
2003 |
Zhong Xi Yi Jie He Xue Bao |
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[Effect and mechanism of Tangshenning Recipe on micro-albuminuria in rats with early diabetic nephropathy]. |
2003 |
Zhong Xi Yi Jie He Xue Bao |
pmid:15339583
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Al-Waili NS and Boni NS |
Natural honey lowers plasma prostaglandin concentrations in normal individuals. |
2003 |
J Med Food |
pmid:12935324
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[Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale]. |
2003 |
Zhongguo Zhong Yao Za Zhi |
pmid:15224660
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Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12639842
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Lipid and protein oxidation contribute to a prothrombotic state in patients with type 2 diabetes mellitus. |
2003 |
J. Thromb. Haemost. |
pmid:12871497
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Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: role of interleukin-6 and disease duration. |
2003 |
Circulation |
pmid:12810609
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Inhibitory mechanisms of metallothionein on platelet aggregation in in vitro and platelet plug formation in in vivo experiments. |
2003 |
Exp. Biol. Med. (Maywood) |
pmid:14681547
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Effects of lipid-esterified conjugated linoleic acid isomers on platelet function: evidence for stimulation of platelet phospholipase activity. |
2003 |
Biochim. Biophys. Acta |
pmid:14729070
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Fujii S et al. |
L-arginine reverses p47phox and gp91phox expression induced by high salt in Dahl rats. |
2003 |
Hypertension |
pmid:14504257
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A new chloroquinolinyl chalcone derivative as inhibitor of inflammatory and immune response in mice and rats. |
2003 |
J. Pharm. Pharmacol. |
pmid:14604476
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Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats. |
2003 |
World J. Gastroenterol. |
pmid:14606091
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Differences in the effects of extended-release aspirin and plain-formulated aspirin on prostanoids and nitric oxide in healthy volunteers. |
2003 |
Fundam Clin Pharmacol |
pmid:12803576
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Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by gram-negative and gram-positive bacterial stimuli. |
2003 |
Shock |
pmid:12813370
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Exhaled leukotrienes and prostaglandins in COPD. |
2003 |
Thorax |
pmid:12832671
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Narghile (water pipe) smoking influences platelet function and (iso-)eicosanoids. |
2003 |
Life Sci. |
pmid:14575812
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Differential effects of 5,6-EET on segmental pulmonary vasoactivity in the rabbit. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
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Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2. |
2003 |
Prostaglandins Other Lipid Mediat. |
pmid:14518563
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Seebacher F and Franklin CE |
Prostaglandins are important in thermoregulation of a reptile (Pogona vitticeps). |
2003 |
Proc. Biol. Sci. |
pmid:12952634
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Cipollone F et al. |
Modulation of aspirin-insensitive eicosanoid biosynthesis by 6-methylprednisolone in unstable angina. |
2003 |
Circulation |
pmid:12515743
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Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
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Genetic variation in cyclooxygenase 1: effects on response to aspirin. |
2003 |
Clin. Pharmacol. Ther. |
pmid:12545150
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Role of thromboxane A2 in early BDL-induced portal hypertension. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:12431905
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Diet rich in saturated fat decreases the ratio of thromboxane/prostacyclin in healthy men. |
2003 |
Biomed. Environ. Sci. |
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[Effect of tetramethylpyrazine on endothelin, von Willebrand factor and thromboxane A2 during cardiopulmonary bypass in patients of congenital heart disease with pulmonary hypertension]. |
2003 |
Zhongguo Zhong Xi Yi Jie He Za Zhi |
pmid:12764908
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[Progress on study of experimental physico-chemical indexes related with ischemic stroke]. |
2003 |
Zhongguo Zhong Xi Yi Jie He Za Zhi |
pmid:12764922
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Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. |
2003 |
J. Nutr. Biochem. |
pmid:14629893
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Sartin JL et al. |
Estradiol plus progesterone treatment modulates select elements of the proinflammatory cytokine cascade in steers: attenuated nitric oxide and thromboxane B2 production in endotoxemia. |
2003 |
J. Anim. Sci. |
pmid:12817503
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Single dose of acetylsalicylic acid prevents thromboxane release after tourniquet ischemia. |
2003 |
J Trauma |
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Dexamethasone suppresses peripheral prostanoid levels without analgesia in a clinical model of acute inflammation. |
2003 |
J. Oral Maxillofac. Surg. |
pmid:12966473
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Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. |
2003 |
J. Nutr. Biochem. |
pmid:12948879
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Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes. |
2003 |
Clin Pharmacokinet |
pmid:12959636
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Effects of diltiazem on platelet activation and cytosolic calcium during percutaneous transluminal coronary angioplasty. |
2003 |
Postgrad Med J |
pmid:13679549
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Clinical implication of the changes of cAMP, TXA2 and PGI2 in CSF of asphyxiated newborns. |
2003 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:12973949
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Aspirin dosage and thromboxane synthesis in patients with vascular disease. |
2003 |
Pharmacotherapy |
pmid:12741431
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Pfeiffer S et al. |
Hyperacute lung rejection in the pig-to-human model. III. Platelet receptor inhibitors synergistically modulate complement activation and lung injury. |
2003 |
Transplantation |
pmid:12698079
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Arifah AK et al. |
Pharmacodynamics, chiral pharmacokinetics and PK-PD modelling of ketoprofen in the goat. |
2003 |
J. Vet. Pharmacol. Ther. |
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Thrombosis and its significance after experimental pulmonary thromboembolism. |
2003 |
Chin. Med. J. |
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