Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Stomach Volvulus D013277 1 associated lipids
Streptococcal Infections D013290 4 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Tachycardia D013610 7 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Thrombasthenia D013915 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Dai CF et al. [Clinical and experimental study of treatment of nanmiqing capsule for chronic prostatitis]. 2002 Zhonghua Nan Ke Xue pmid:12479132
Khan I et al. Cyclooxygenase-2 inhibition and experimental colitis: beneficial effects of phosphorothioated antisense oligonucleotide and meloxicam. 2002 Scand. J. Gastroenterol. pmid:12523593
Ozaki N et al. Differential regulation of prostacyclin and thromboxane by dexamethasone and celecoxib during oxidative stress in newborn rabbits. 2002 Prostaglandins Other Lipid Mediat. pmid:12428679
Huang F et al. Anti-platelet and anti-thrombotic effects of triacetylshikimic acid in rats. 2002 J. Cardiovasc. Pharmacol. pmid:11791012
Bayorh MA et al. 1A-779 attenuates angiotensin-(1-7) depressor response in salt-induced hypertensive rats. 2002 Peptides pmid:11814618
Jeng JH et al. Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase. 2002 Free Radic. Biol. Med. pmid:11978487
Saareks V et al. Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man. 2002 Pharmacol. Toxicol. pmid:12403056
Sinzinger H Comments on "Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications". 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12445490
Burleigh ME et al. Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice. 2002 Circulation pmid:11956125
Jankov RP et al. Thromboxane A(2) receptors mediate pulmonary hypertension in 60% oxygen-exposed newborn rats by a cyclooxygenase-independent mechanism. 2002 Am. J. Respir. Crit. Care Med. pmid:12119234
Giardiello FM et al. Primary chemoprevention of familial adenomatous polyposis with sulindac. 2002 N. Engl. J. Med. pmid:11932472
Signorello MG et al. Effect of homocysteine on arachidonic acid release in human platelets. 2002 Eur. J. Clin. Invest. pmid:11952814
Yamasaki M et al. No involvement of interleukin-5 or eosinophils in experimental allergic rhinitis in guinea pigs. 2002 Eur. J. Pharmacol. pmid:11937106
Khan I et al. Altered expression of Na(+)/H(+) exchanger isoforms 1 and 3 in clipped and unclipped kidneys of a 2-kidney-1-clip Goldblatt model of hypertension. 2002 Nephron pmid:12218313
Yokoyama C et al. Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction. 2002 Circulation pmid:12403673
Evgenov OV et al. Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep. 2002 Eur. Respir. J. pmid:12412689
Bergh K et al. Production of prostaglandin e(2) by iridial melanocytes exposed to latanoprost acid, a prostaglandin F(2 alpha) analogue. 2002 J Ocul Pharmacol Ther pmid:12419090
Chen TL et al. [Effects of fast decompression on prostaglandins content in cerebral tissue of guinea pigs]. 2002 Space Med Med Eng (Beijing) pmid:12222577
Kim H et al. Effect of mannitol on Helicobacter pylori-induced cyclooxygenase-2 expression in gastric epithelial AGS cells. 2002 Pharmacology pmid:12393940
Shashikant MP et al. Physicochemical properties of perfluorochemical liquids influence ventilatory requirements, pulmonary mechanics, and microvascular permeability during partial liquid ventilation following intestinal ischemia/reperfusion injury. 2002 Crit. Care Med. pmid:12394959
Dionne RA et al. Analgesia and COX-2 inhibition. 2001 Nov-Dec Clin. Exp. Rheumatol. pmid:11695255
Resnick DK et al. Regional and temporal changes in prostaglandin E2 and thromboxane B2 concentrations after spinal cord injury. 2001 Nov-Dec Spine J pmid:14588301
Resnick DK et al. Selective cyclooxygenase 2 inhibition lowers spinal cord prostaglandin concentrations after injury. 2001 Nov-Dec Spine J pmid:14588302
Nakamura H et al. Difference in urinary 11-dehydro TXB2 and LTE4 excretion in patients with rheumatoid arthritis. 2001 Nov-Dec Prostaglandins Leukot. Essent. Fatty Acids pmid:11993724
Rebrov BA [Role of thromboxane A2 (B2) in the pathogenesis of stress proteinuria in healthy persons]. 2001 Mar-Apr Urologiia pmid:11490711
Minuz P et al. NCX4016 (NO-aspirin) inhibits thromboxane biosynthesis and tissue factor expression and activity in human monocytes. 2001 Jul-Aug Med. Sci. Monit. pmid:11433179
Clayton HA et al. A coculture model of intrahepatic islet transplantation: activation of Kupffer cells by islets and acinar tissue. 2001 Jan-Feb Cell Transplant pmid:11294466
Uchiyama M et al. Comparison between nonpulsatile and pulsatile machine perfusion preservation in liver transplantation from non-heart-beating donors. 2001 Feb-Mar Transplant. Proc. pmid:11267136
Oikawa K et al. Elimination of Kupffer cells suppresses activation of nuclear factor kappa B and production of cytokines and eicosanoids in non-heart-beating donors. 2001 Feb-Mar Transplant. Proc. pmid:11267090
Okita M et al. Effect of arachidonic acid-rich oil on lipids and arachidonate metabolites in ethanol- treated rats. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418023
Karamouzis M et al. The response of muscle interstitial prostaglandin E(2)(PGE(2)), prostacyclin I(2)(PGI(2)) and thromboxane A(2)(TXA(2)) levels during incremental dynamic exercise in humans determined by in vivo microdialysis. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418021
Bölke E et al. Changes of gut barrier function during anesthesia and cardiac surgery. 2001 Angiology pmid:11515987
Grace RF et al. Effects of diclofenac in the rat tail ischaemia--reperfusion injury model of acute hyperalgesia. 2001 Pain pmid:11166467
Watanabe T et al. Enhanced platelet sensitivity to prostacyclin in patients in an active stage of Takayasu arteritis. 2001 Thromb. Res. pmid:11672751
Ziegler BK et al. Incomplete thromboxane inhibition with 100 mg of intravenous acetylsalicylic acid in patients with acute ST elevation myocardial infarction: a placebo-controlled pilot trial. 2001 Thromb. Res. pmid:11672759
Nüsing RM et al. Pathogenetic role of cyclooxygenase-2 in hyperprostaglandin E syndrome/antenatal Bartter syndrome: therapeutic use of the cyclooxygenase-2 inhibitor nimesulide. 2001 Clin. Pharmacol. Ther. pmid:11673754
Llinás MT et al. Role of COX-2-derived metabolites in regulation of the renal hemodynamic response to norepinephrine. 2001 Am. J. Physiol. Renal Physiol. pmid:11592955
Kitamura R et al. Thiopental enhances human platelet aggregation by increasing arachidonic acid release. 2001 Can. J. Physiol. Pharmacol. pmid:11697744
Ferlito M et al. Effect of cross-tolerance between endotoxin and TNF-alpha or IL-1beta on cellular signaling and mediator production. 2001 J. Leukoc. Biol. pmid:11698503
Brideau C et al. In vitro effects of cyclooxygenase inhibitors in whole blood of horses, dogs, and cats. 2001 Am. J. Vet. Res. pmid:11703020
Bing RJ et al. Nitric oxide, prostanoids, cyclooxygenase, and angiogenesis in colon and breast cancer. 2001 Clin. Cancer Res. pmid:11705852
Jilma-Stohlawetz P et al. Impaired platelet function among platelet donors. 2001 Thromb. Haemost. pmid:11583322
Moreno JJ Antiflammin-2 prevents HL-60 adhesion to endothelial cells and prostanoid production induced by lipopolysaccharides. 2001 J. Pharmacol. Exp. Ther. pmid:11181920
Vagnoni KE et al. The influence of the phase of the estrous cycle on sheep endometrial tissue response to lipopolysaccharide. 2001 J. Anim. Sci. pmid:11219456
Blann AD et al. Changes in endothelial, leucocyte and platelet markers following contrast medium injection during angiography in patients with peripheral artery disease. 2001 Br J Radiol pmid:11560828
Martinuzzo ME et al. Increased lipid peroxidation correlates with platelet activation but not with markers of endothelial cell and blood coagulation activation in patients with antiphospholipid antibodies. 2001 Br. J. Haematol. pmid:11564073
Iuliano L et al. Angioplasty increases coronary sinus F2-isoprostane formation: evidence for in vivo oxidative stress during PTCA. 2001 J. Am. Coll. Cardiol. pmid:11153776
Van Solingen RM et al. Comparison of the effects of ketoprofen on platelet function in the presence and absence of aspirin. 2001 Am. J. Med. pmid:11566459
Chen CH et al. [Simultaneously analysis of 15 parameters in the patients with the liver-blood deficiency syndrome]. 2001 Hunan Yi Ke Da Xue Xue Bao pmid:12536728
Ploner F et al. Effects of combined selective iNOS inhibition and peroxynitrite blockade during endotoxemia in pigs. 2001 Shock pmid:11508865
Diebolt M et al. Wine polyphenols decrease blood pressure, improve NO vasodilatation, and induce gene expression. 2001 Hypertension pmid:11509469
Tomida T et al. Altered expression of prostacyclin synthase in a subset of the thick ascending limb cells and mesangial cells in 5/6-nephrectomized rats. 2001 Hypertens. Res. pmid:11510754
Valeri CR et al. Anemia-induced increase in the bleeding time: implications for treatment of nonsurgical blood loss. 2001 Transfusion pmid:11493727
Ogata K et al. Attenuation of ischemia and reperfusion injury of canine livers by inhibition of type II phospholipase A2 with LY329722. 2001 Transplantation pmid:11374398
Guyton K et al. Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation. 2001 J. Leukoc. Biol. pmid:11310850
Oketani K et al. In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production. 2001 Eur. J. Pharmacol. pmid:11430933
Urquhart P et al. Profile of eicosanoids produced by human saphenous vein endothelial cells and the effect of dietary fatty acids. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11487303
Zoja C et al. Mycophenolate mofetil combined with a cyclooxygenase-2 inhibitor ameliorates murine lupus nephritis. 2001 Kidney Int. pmid:11473648
Alcaraz A et al. Experimental kidney transplantation in pigs from non-heart-beating donors: evaluation of vasoactive substances and renal artery flow. 2001 Transplant. Proc. pmid:11543815
Feng TC et al. Effect of valsartan and captopril in rabbit carotid injury. Possible involvement of bradykinin in the antiproliferative action of the renin-angiotensin blockade. 2001 J Renin Angiotensin Aldosterone Syst pmid:11881060
Catella-Lawson F et al. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. 2001 N. Engl. J. Med. pmid:11752357
Kijima Y et al. Transcardiac 8-iso-prostaglandin F(2 alpha)generation from acute myocardial infarction heart: insight into abrupt reperfusion and oxidant stress. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11334551
Ochi T and Goto T Anti-inflammatory activity of a novel selective cyclooxygenase-2 inhibitor, FR140423, on type II collagen-induced arthritis in Lewis rats. 2001 Prostaglandins Other Lipid Mediat. pmid:11785783
Gao YJ and Lee RM Hydrogen peroxide induces a greater contraction in mesenteric arteries of spontaneously hypertensive rats through thromboxane A(2) production. 2001 Br. J. Pharmacol. pmid:11739239
Engström K et al. Effect of low-dose aspirin in combination with stable fish oil on whole blood production of eicosanoids. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11427037
Gloor B et al. Hydrocortisone treatment of early SIRS in acute experimental pancreatitis. 2001 Dig. Dis. Sci. pmid:11680590
Stichtenoth DO et al. Effects of intravenous oxygen on prostacyclin and thromboxane formation in patients with peripheral occlusive arterial disease. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728174
Sunose Y et al. Effect of a cyclooxygenase-2 inhibitor, FK3311, in a canine lung transplantation model. 2001 Ann. Thorac. Surg. pmid:11603431
Minuz P et al. NCX4016 (NO-Aspirin) has multiple inhibitory effects in LPS-stimulated human monocytes. 2001 Br. J. Pharmacol. pmid:11606332
Turull A et al. Acute effects of the anti-inflammatory cyclooxygenase-2 selective inhibitor, flosulide, on renal plasma flow and glomerular filtration rate in rats. 2001 Inflammation pmid:11321358
Skovronsky DM et al. Amyloid precursor protein and amyloid beta peptide in human platelets. Role of cyclooxygenase and protein kinase C. 2001 J. Biol. Chem. pmid:11278299
Lim JW et al. Nuclear factor-kappaB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells. 2001 Lab. Invest. pmid:11310828
Oketani K et al. Effect of E3040, an inhibitor of 5-lipoxygenase and thromboxane synthase, on rat bowel damage induced by lipopolysaccharide. 2001 Eur. J. Pharmacol. pmid:11557269
Karamouzis M et al. In situ microdialysis of intramuscular prostaglandin and thromboxane in contracting skeletal muscle in humans. 2001 Acta Physiol. Scand. pmid:11350265
Komers R et al. Immunohistochemical and functional correlations of renal cyclooxygenase-2 in experimental diabetes. 2001 J. Clin. Invest. pmid:11285308
Chen CY and Lin TH Effects of nickel chloride on human platelets: enhancement of lipid peroxidation, inhibition of aggregation and interaction with ascorbic acid. 2001 J. Toxicol. Environ. Health Part A pmid:11289317
Kawaguchi A et al. Preventive effect of platelet-activating factor antagonist, Y-24180, against cyclosporine-induced acute nephrotoxicity. 2001 Life Sci. pmid:11228102
Seno K et al. Pyrrolidine inhibitors of human cytosolic phospholipase A2. Part 2: synthesis of potent and crystallized 4-triphenylmethylthio derivative 'pyrrophenone'. 2001 Bioorg. Med. Chem. Lett. pmid:11229777
Wight NJ et al. Rofecoxib, a COX-2 inhibitor, does not inhibit human gastric mucosal prostaglandin production. 2001 Gastroenterology pmid:11231941
Praticò D et al. Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11248083
Hishinuma T et al. Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728171
Kaaja R et al. Increased thromboxane production in women with a history of venous thromboembolic event: effect of heparins. 2001 Br. J. Haematol. pmid:11552994
Gossmann J et al. Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide? 2001 Kidney Blood Press. Res. pmid:11435743
Cantaro S et al. Urinary excretion of vasoactive substances in chronic renal failure. 2001 Clin. Nephrol. pmid:11393385
Kurokawa K et al. Circadian characteristics of urinary leukotriene E(4) in healthy subjects and nocturnal asthmatic patients. 2001 Chest pmid:11742908
Feldman M et al. A comparison of every-third-day versus daily low-dose aspirin therapy on serum thromboxane concentrations in healthy men and women. 2001 Clin. Appl. Thromb. Hemost. pmid:11190906
Tuppo EE et al. Sign of lipid peroxidation as measured in the urine of patients with probable Alzheimer's disease. 2001 Brain Res. Bull. pmid:11397549
Norio K et al. Eicosanoids and delayed graft function in human renal transplantation. 2001 Transplant. Proc. pmid:11406239
Galipeau D et al. Chronic thromboxane synthase inhibition prevents fructose-induced hypertension. 2001 Hypertension pmid:11641301
Tubaro E et al. Anti-inflammatory and antiplatelet effects of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug. 2001 Arzneimittelforschung pmid:11642006
Spinarová L et al. [Physical training in patients with chornic heart failure: haemodynamics, effects]. 2001 Vnitr Lek pmid:15635849
Tran HS et al. Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock. 2001 Crit. Care Med. pmid:11445706
Sontag W Release of mediators by DMSO-differentiated HL-60 cells exposed to electric interferential current and the requirement of biochemical prestimulation. 2001 Int. J. Radiat. Biol. pmid:11403712
Machin KL et al. Pharmacodynamics of flunixin and ketoprofen in mallard ducks (Anas platyrhynchos). 2001 J. Zoo Wildl. Med. pmid:12790425
Shah AA et al. Selective inhibition of COX-2 in humans is associated with less gastrointestinal injury: a comparison of nimesulide and naproxen. 2001 Gut pmid:11171823
Yeh CH et al. Pharmacological characterization and antithrombotic effect of agkistin, a platelet glycoprotein Ib antagonist. 2001 Br. J. Pharmacol. pmid:11181425
Sunose Y et al. The effect of cyclooxygenase-2 inhibitor FK3311 on ischemia-reperfusion injury in a canine total hepatic vascular exclusion model. 2001 J. Am. Coll. Surg. pmid:11192923
Arifah AK et al. Pharmacodynamics and pharmacokinetics of ketoprofen enantiomers in sheep. 2001 Am. J. Vet. Res. pmid:11197566
Carvalho CR et al. Antigen-induced bronchial hyperreactivity and bronchopulmonary inflammation in rats: effect of TNF receptor binding protein. 2001 Exp. Lung Res. pmid:11258800
Suliman HB et al. Prevention of influenza-induced lung injury in mice overexpressing extracellular superoxide dismutase. 2001 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:11133496