Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Stomach Volvulus D013277 1 associated lipids
Streptococcal Infections D013290 4 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Tachycardia D013610 7 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Thrombasthenia D013915 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Buchanan MR et al. Aspirin inhibits platelet function independent of the acetylation of cyclo-oxygenase. 1982 Thromb. Res. pmid:7071811
Tremoli E et al. Metformin reduces platelet hypersensitivity in hypercholesterolemic rabbits. 1982 Atherosclerosis pmid:7073794
Tanabe M et al. Coronary circulatory failure and thromboxane A2 release during coronary occlusion and reperfusion in anaesthetised dogs. 1982 Cardiovasc. Res. pmid:7074670
Peterson MB et al. Thromboxane mediates acute pulmonary hypertension in sheep extracorporeal perfusion. 1982 Am. J. Physiol. pmid:7051860
Grundfest CC et al. Acrolein: a potent modulator of lung macrophage arachidonic acid metabolism. 1982 Biochim. Biophys. Acta pmid:6814492
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Tooke JE et al. Aspirin, prostacyclin and post-occlusive reactive hyperaemia in man. 1982 Prostaglandins Leukot Med pmid:6757966
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Hornych A et al. Radioimmunoassay measurement of thromboxane B2 in human plasma and urine. 1982 Prostaglandins Leukot Med pmid:6954551
Mest HJ et al. Influence of mental stress on plasma level of prostaglandins, thromboxane B2 and on circulating platelet aggregates in man. 1982 Prostaglandins Leukot Med pmid:6955811
Karmali RA et al. Macrophage production of prostaglandins: effects of fetal calf serum and diazepam. Use of an improved method for extracting 6-keto-PGF1 alpha. 1982 Prostaglandins Leukot Med pmid:6955812
Mehta J et al. Severe intracoronary thromboxane release preceding acute coronary artery occlusion. 1982 Prostaglandins Leukot Med pmid:6955814
Foegh ML et al. Aspirin inhibition of thromboxane release in thrombosis and renal transplant rejection. 1982 Lancet pmid:6119441
Graham RM et al. Effects of short-term beta blockade on blood pressure, plasma thromboxane B2, and plasma and urinary prostaglandins E2 and F2 alpha in normal subjects. 1982 Clin. Pharmacol. Ther. pmid:6120775
Reines HD et al. Plasma thromboxane concentrations are raised in patients dying with septic shock. 1982 Lancet pmid:6123885
White JG and Rao GH Effects of a microtubule stabilizing agent on the response of platelets to vincristine. 1982 Blood pmid:6124288
Chong BH et al. Heparin-induced thrombocytopenia: association of thrombotic complications with heparin-dependent IgG antibody that induces thromboxane synthesis in platelet aggregation. 1982 Lancet pmid:6128550
Havill AM et al. alpha-Naphthylthiourea produces dose-dependent lung vascular injury in sheep. 1982 Am. J. Physiol. pmid:6812437
Preston FE et al. Low-dose aspirin inhibits platelet and venous cyclo-oxygenase in man. 1982 Thromb. Res. pmid:6815823
Burch RM and Halushka PV Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells. 1982 Am. J. Physiol. pmid:6816073
Steel LK and Catravas GN Radiation-induced changes in production of prostaglandins F2 alpha, E, and thromboxane B2 in guinea pig parenchymal lung tissues. 1982 Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. pmid:6818175
Srivastava KC and Awasthi KK A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-14C) arachidonic acid. 1982 Prostaglandins Leukot Med pmid:6818563
Neri Serheri GG et al. Platelet aggregation and thromboxane A2 production after adrenergic stimulation in young healthy humans. 1982 Haemostasis pmid:6279476
Dore-Duffy P Differential effect of prostaglandins and other products of arachidonic acid metabolism on measles virus replication in Vero cells. 1982 Prostaglandins Leukot Med pmid:6281810
Miller OV et al. Acetyl glycerylphosphorylcholine inhibition of prostaglandin I2-stimulated adenosine 3',5'-cyclic monophosphate levels in human platelets. Evidence for thromboxane A2 dependence. 1982 Biochim. Biophys. Acta pmid:6285985
Jackson CA et al. Relationship between platelet aggregation, thromboxane synthesis and albumin concentration in nephrotic syndrome. 1982 Br. J. Haematol. pmid:6810912
Schafer AI et al. Platelet lipoxygenase-dependent oxygen burst. Evidence for differential activation of lipoxygenase in intact and disrupted human platelets. 1982 Biochim. Biophys. Acta pmid:6812645
Kelton JG et al. Sex-related differences in the efficacy of acetylsalicylic acid (ASA) : the absorption of ASA and its effect on collagen-induced thromboxane B2 generation. 1981 Oct 1-15 Thromb. Res. pmid:7330835
Randall MJ et al. UK-37, 248, a novel, selective thromboxane synthetase inhibitor with platelet anti-aggregatory and anti-thrombotic activity. 1981 Jul 1-15 Thromb. Res. pmid:6795753
Tsuboi T et al. Effect of gliclazide on prostaglandin and thromboxane synthesis in guinea-pig platelets. 1981 Jan 1-15 Thromb. Res. pmid:7233394
Bockman RS Prostaglandin production by human blood monocytes and mouse peritoneal macrophages: synthesis dependent on in vitro culture conditions. 1981 Prostaglandins pmid:6782622
Rittenhouse-Simmons S Differential activation of platelet phospholipases by thrombin and ionophore A23187. 1981 J. Biol. Chem. pmid:6783655
Galli C et al. Differential effects of dietary fatty acids on the accumulation of arachidonic acid and its metabolic conversion through the cyclooxygenase and lipoxygenase in platelets and vascular tissue. 1981 Lipids pmid:6783805
Sakio H et al. [Release of thromboxane A2 during hemorrhagic shock (author's transl)]. 1981 Masui pmid:7218508
Kawaguchi H et al. Thromboxane B2 biosynthesis and phospholipids hydrolysis in platelets from hypercholesterolemic rabbits. 1981 Lipids pmid:7219079
Sirois P et al. Comparative effects of leukotriene B4, prostaglandins I2 and E2, 6-keto-PGF1 alpha thromboxane B2 and histamine on selected smooth muscle preparations. 1981 J. Pharm. Pharmacol. pmid:6115037
Coker SJ et al. Aspirin inhibits the early myocardial release of thromboxane B2 and ventricular ectopic activity following acute coronary artery occlusion in dogs. 1981 Br. J. Pharmacol. pmid:7284679
Rifkin BR and Tai HH Elevated thromboxane B2 levels in periodontal disease. 1981 J. Periodont. Res. pmid:6453981
Rubenstein MD et al. Platelet activation in clinical coronary artery disease and spasm. 1981 Am. Heart J. pmid:6455912
Harms BA et al. Prostaglandin release and altered microvascular integrity after burn injury. 1981 J. Surg. Res. pmid:6895238
Ylikorkala O et al. Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies. 1981 Am. J. Obstet. Gynecol. pmid:6895277
Ishihara Y et al. [Effect of hypoxemia and pulmonary thromboembolism on plasma levels of 6-keto PGF 1 alpha, TxB, histamine and serotonin in anesthetized dogs (author's transl)]. 1981 Nihon Kyobu Shikkan Gakkai Zasshi pmid:6895531
Kinney EL and Demers LM Plasma 6 keto PGE1 alpha concentration in Raynaud's phenomenon. 1981 Prostaglandins Med pmid:6895673
Barnett AH et al. Circulating prostanoid levels, both basal and during the chlorpropamide alcohol flush, in non-insulin dependent diabetes. 1981 Clin. Endocrinol. (Oxf) pmid:6895721
Agradi E et al. In vitro effects of synthetic antioxidants and vitamin E on arachidonic acid metabolism and thromboxane formation in human platelets and on platelet aggregation. 1981 Prostaglandins pmid:6794104
Russell NH et al. Platelet adenine nucleotides and arachidonic acid metabolism in the myeloproliferative disorders. 1981 Thromb. Res. pmid:6794179
Beck N and Shaw JO Thromboxane B2 and prostaglandin E2 in the K+-depleted rat kidney. 1981 Am. J. Physiol. pmid:7468800
Hwang DH et al. In vitro and in vivo effects of ethanol on the formation of endoperoxide metabolites in rat platelets. 1981 Lipids pmid:6792442