| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension, Pulmonary | D006976 | 32 associated lipids |
| Stroke | D020521 | 32 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Ventricular Dysfunction, Left | D018487 | 33 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Spinal Cord Injuries | D013119 | 34 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Infarction, Middle Cerebral Artery | D020244 | 35 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zeng W and Zhang M | [Relationship between the alteration of 6-keto-PGF1 alpha and TXB2 in cervical mucus of patients with threatened preterm labor and the efficacy of magnesium sulfate treatment]. | 2000 | Hua Xi Yi Ke Da Xue Xue Bao | pmid:12501615 |
| Khan HH et al. | Plasma CPU-86017 concentrations regarding suppression of ouabain-induced cardiac arrhythmias and decrease of heart rate in guinea pigs. | 2000 | Acta Pharmacol. Sin. | pmid:11501061 |
| Wang W et al. | Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. | 2000 | Acta Pharmacol. Sin. | pmid:11501172 |
| Tanus-Santos JE et al. | The hemodynamic effects of endothelin receptor antagonism during a venous air infusion in dogs. | 2000 | Anesth. Analg. | pmid:10624986 |
| Praticò D et al. | Endogenous biosynthesis of thromboxane and prostacyclin in 2 distinct murine models of atherosclerosis. | 2000 | Blood | pmid:11090066 |
| Boatman RJ et al. | Covalent protein adducts of hydroquinone in tissues from rats: quantitation of sulfhydryl-bound forms following single gavage or intraperitoneal administration or repetitive gavage administration. | 2000 | Chem. Res. Toxicol. | pmid:10995259 |
| Belton O et al. | Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. | 2000 | Circulation | pmid:10952950 |
| Jacobi KE et al. | Determination of eicosanoid and cytokine production in salvaged blood, stored red blood cell concentrates, and whole blood. | 2000 | J Clin Anesth | pmid:10818321 |
| Tanus-Santos JE et al. | Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. | 2000 | Eur. J. Pharmacol. | pmid:10822051 |
| Turpeinen AM et al. | Similar responses in hemostatic factors after consumption of wholemeal rye bread and low-fiber wheat bread. | 2000 | Eur J Clin Nutr | pmid:10822290 |
| Romano M et al. | Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide. | 2000 | J. Investig. Med. | pmid:10822898 |
| Sheu JR et al. | Mechanisms involved in the antiplatelet activity of Staphylococcus aureus lipoteichoic acid in human platelets. | 2000 | Thromb. Haemost. | pmid:10823277 |
| Zhou L et al. | [The effect of plasma from women with preeclampsia on endothelial cells activators in vitro]. | 2000 | Zhonghua Fu Chan Ke Za Zhi | pmid:11776183 |
| Nosál' R et al. | Chloroquine: a multipotent inhibitor of human platelets in vitro. | 2000 | Thromb. Res. | pmid:10828481 |
| Homoncik M et al. | Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100. | 2000 | Thromb. Haemost. | pmid:10739392 |
| Schweizer A et al. | Aprotinin does not impair renal haemodynamics and function after cardiac surgery. | 2000 | Br J Anaesth | pmid:10740541 |
| Agnoli GC et al. | Renal synthesis of prostacyclin and thromboxane in healthy women: differential effects of a short-term saline loading. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780876 |
| Wakitani K et al. | JTE-522 selectively inhibits cyclooxygenase-2-derived prostaglandin production in inflammatory tissues. | 2000 | Inflamm. Res. | pmid:10807499 |
| Rilantono LI et al. | Dietary antioxidative potential in arteries. | 2000 | Clin. Hemorheol. Microcirc. | pmid:11321428 |
| Liao CH et al. | Antiplatelet effect of marchantinquinone, isolated from Reboulia hemisphaerica, in rabbit washed platelets. | 2000 | J. Pharm. Pharmacol. | pmid:10757426 |
| Prieto MA et al. | Influence of triflusal on platelet activation after coronary artery bypass graft. | 2000 | Blood Coagul. Fibrinolysis | pmid:10759013 |
| Heller A et al. | The complement regulators C1 inhibitor and soluble complement receptor 1 attenuate acute lung injury in rabbits. | 2000 | Shock | pmid:10774617 |
| Sane S et al. | Eicosapentaenoic acid reduces pulmonary edema in endotoxemic rats. | 2000 | J. Surg. Res. | pmid:10945939 |
| Patrignani P et al. | Effects of vitamin E supplementation on F(2)-isoprostane and thromboxane biosynthesis in healthy cigarette smokers. | 2000 | Circulation | pmid:10920066 |
| Cruz MA et al. | Vascular reactivity to angiotensin II and eicosanoid production in the human placenta from term and preterm pregnancy. | 2000 | Gynecol. Obstet. Invest. | pmid:11093047 |
| Kasahara M et al. | Effect of FK3311 on ischemia-reperfusion injury in canine pulmonary models. | 2000 | Transplant. Proc. | pmid:11120230 |
| De Jong A et al. | Antiphospholipid antibodies and platelets. | 2000 | Curr Rheumatol Rep | pmid:11123065 |
| Buccellati C et al. | Tramadol anti-inflammatory activity is not related to a direct inhibitory action on prostaglandin endoperoxide synthases. | 2000 | Eur J Pain | pmid:11124014 |
| Basu S et al. | Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity. | 2000 | Clin. Sci. | pmid:11099394 |
| Filipov NM et al. | Anti-inflammatory effects of ergotamine in steers. | 2000 | Proc. Soc. Exp. Biol. Med. | pmid:11044256 |
| Numminen H et al. | The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation. | 2000 | Stroke | pmid:10835443 |
| Kawasaki K et al. | Inhibition of 12(S)-hydroxyeicosatetraenoic acid (12-HETE) production suppressed the intimal hyperplasia caused by poor-runoff conditions in the rabbit autologous vein grafts. | 2000 | J. Cardiovasc. Pharmacol. | pmid:11065214 |
| Tsikas D et al. | Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine. | 2000 | J Chromatogr A | pmid:10941682 |
| Vazquez-Cruz B et al. | Increased renal vasoconstriction and gene expression of cyclooxygenase-1 in renovascular hypertension. | 2000 | J. Cardiovasc. Pharmacol. | pmid:11065217 |
| Greenberg HE et al. | A new cyclooxygenase-2 inhibitor, rofecoxib (VIOXX), did not alter the antiplatelet effects of low-dose aspirin in healthy volunteers. | 2000 | J Clin Pharmacol | pmid:11185674 |
| Siler-Khodr TM et al. | Effect of ethanol on thromboxane and prostacyclin production in the human placenta. | 2000 | Alcohol | pmid:10963940 |
| Laguna MS et al. | [Thromboxane B2 and platelet derived growth factor in essential thrombocythemia treated with anagrelide]. | 2000 | Medicina (B Aires) | pmid:11188949 |
| Matz RL et al. | Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids. | 2000 | Br. J. Pharmacol. | pmid:10991924 |
| Tanaka H et al. | Effects of milrinone on platelet aggregation in swine with pulmonary hypertension. | 2000 | J Crit Care | pmid:11011824 |
| Cracowski JL et al. | Human internal mammary artery contraction by isoprostaglandin f(2alpha) type-III [8-iso-prostaglandin F(2alpha)]. | 2000 | Eur. J. Pharmacol. | pmid:10844110 |
| Coppola A et al. | Homocysteine, coagulation, platelet function, and thrombosis. | 2000 | Semin. Thromb. Hemost. | pmid:11011842 |
| Kim WG et al. | Is avoidance of air contact necessary for the in vitro evaluation of thrombogenicity in mechanical circulatory assist devices? | 2000 | Artif Organs | pmid:11012543 |
| Kim WG et al. | Vasoconstrictive eicosanoid responses to extracorporeal circulation with or without an oxygenator in fetal lambs. | 2000 | Int J Artif Organs | pmid:10941636 |
| Porta C et al. | Amifostine, a reactive oxigen species scavenger with radiation- and chemo-protective properties, inhibits in vitro platelet activation induced by ADP, collagen or PAF. | 2000 | Haematologica | pmid:10942928 |
| Wang JS et al. | Effect of strenuous arm exercise on oxidized-LDL-potentiated platelet activation in individuals with spinal cord injury. | 2000 | Thromb. Haemost. | pmid:10928481 |
| Krysztopik RJ et al. | Lazaroid and pentoxifylline suppress sepsis-induced increases in renal vascular resistance via altered arachidonic acid metabolism. | 2000 | J. Surg. Res. | pmid:10945946 |
| Stanke-Labesque F et al. | Angiotensin II-induced contractions in human internal mammary artery: effects of cyclooxygenase and lipoxygenase inhibition. | 2000 | Cardiovasc. Res. | pmid:10946074 |
| Moosig F et al. | Opsonization of apoptotic neutrophils by anti-neutrophil cytoplasmic antibodies (ANCA) leads to enhanced uptake by macrophages and increased release of tumour necrosis factor-alpha (TNF-alpha). | 2000 | Clin. Exp. Immunol. | pmid:11122261 |
| Yu K et al. | [Clinical observation on treatment of pediatric intractable nephropathy with modified taohong siwu decoction]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938829 |
| Toft G et al. | Intravenously and topically applied magnesium in the prevention of arterial thrombosis. | 2000 | Thromb. Res. | pmid:10904104 |
| Shi X et al. | [Effects of Salvia miltiorrhiza compound injection on serum endothelin, prostaglandin I2/thromboxane A2 ratio alteration following myocardial ischemia-reperfusion in patients undergoing intracardiac surgery]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938858 |
| Giedrojć J et al. | [Investigation of prostaglandins in supernatant of cultured monocytes]. | 2000 | Prz. Lek. | pmid:10907365 |
| Miao X et al. | [Effect of yinchen dandao decoction on plasma fibronectin, biliary thromboxane A2 and prostaglandin I2 in human and animal suffering from acute cholangitis]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938860 |
| Momi S et al. | Involvement of platelets in experimental mouse trypanosomiasis: evidence of mouse platelet cytotoxicity against Trypanosoma equiperdum. | 2000 | Exp. Parasitol. | pmid:10910715 |
| Moon CH et al. | Mechanism for antiplatelet effect of onion: AA release inhibition, thromboxane A(2)synthase inhibition and TXA(2)/PGH(2)receptor blockade. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883058 |
| Lasserre B et al. | Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883059 |
| Arakida Y et al. | Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs. | 2000 | Eur. J. Pharmacol. | pmid:10969159 |
| Bereczki C et al. | The roles of platelet function, thromboxane, blood lipids and nitric oxide in hypertension of children and adolescents. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883060 |
| Carty E et al. | Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848666 |
| Dschietzig T et al. | Stimulation of pulmonary big endothelin-1 and endothelin-1 by antithrombin III: a rationale for combined application of antithrombin III and endothelin antagonists in sepsis-related acute respiratory distress syndrome? | 2000 | Crit. Care Med. | pmid:10921577 |
| Muscará MN et al. | Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10924050 |
| Mizugaki M | [Microdetermination of eicosanoids using mass spectrometry]. | 2000 | Nippon Yakurigaku Zasshi | pmid:10876809 |
| Depré M et al. | Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans. | 2000 | Eur. J. Clin. Pharmacol. | pmid:10877012 |
| Theriot JA et al. | Dietary chloride does not correlate with urinary thromboxane in deoxycorticosterone acetate-treated rats. | 2000 | J. Lab. Clin. Med. | pmid:10850649 |
| Kowalska MA et al. | Stromal cell-derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets. | 2000 | Blood | pmid:10891429 |
| Bailey SR et al. | Differential activation of platelets from normal and allergic ponies by PAF and ADP. | 2000 | Inflamm. Res. | pmid:10893045 |
| Rao AR and Prabhakar MC | Screening methods for antiasthmatic agents. | 2000 | Methods Find Exp Clin Pharmacol | pmid:10893704 |
| Cayatte AJ et al. | The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo E-deficient mice: evidence that eicosanoids other than thromboxane contribute to atherosclerosis. | 2000 | Arterioscler. Thromb. Vasc. Biol. | pmid:10894809 |
| Pärsson HN et al. | Maintaining carotid flow by shunting during carotid endarterectomy diminishes the inflammatory response mediating ischaemic brain injury. | 2000 | Eur J Vasc Endovasc Surg | pmid:10727360 |
| Tegeder I et al. | Effects of selective and unselective cyclooxygenase inhibitors on prostanoid release from various rat organs. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688636 |
| Rioja I et al. | An anti-inflammatory ditriazine inhibiting leukocyte functions and expression of inducible nitric oxide synthase and cyclo-oxygenase-2. | 2000 | Eur. J. Pharmacol. | pmid:10844115 |
| Tran HS et al. | The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock. | 2000 | Shock | pmid:10847636 |
| Maccarrone M et al. | Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833416 |
| Gardan B et al. | Vasoconstrictor effects of iso-prostaglandin F2alpha type-III (8-iso-prostaglandin F2alpha) on human saphenous veins. | 2000 | J. Cardiovasc. Pharmacol. | pmid:10813374 |
| Suntres ZE and Shek PN | Prophylaxis against lipopolysaccharide-induced lung injuries by liposome-entrapped dexamethasone in rats. | 2000 | Biochem. Pharmacol. | pmid:10704946 |
| Giedrojć J et al. | [Interaction of platelets with monocytes with regard to arachidonic acid metabolites]. | 2000 | Prz. Lek. | pmid:11199865 |
| Cryer B et al. | Effects of cutaneous aspirin on the human stomach and duodenum. | 1999 Sep-Oct | Proc. Assoc. Am. Physicians | pmid:10519166 |
| Stewart KG et al. | Estrogen decreases prostaglandin H synthase products from endothelial cells. | 1999 Nov-Dec | J. Soc. Gynecol. Investig. | pmid:10643586 |
| Tong H et al. | Prostaglandin endoperoxide synthase-2 abundance is increased in brain tissues of late-gestation fetal sheep in response to cerebral hypoperfusion. | 1999 May-Jun | J. Soc. Gynecol. Investig. | pmid:10376268 |
| Uriu K et al. | Effect of acute thromboxane A2 inhibition on the renal hemodynamics in a spontaneously non-insulin-dependent diabetic rat, Otsuka Long-Evans Tokushima Fatty rat. | 1999 Jul-Aug | J. Diabetes Complicat. | pmid:10616856 |
| Pestana M et al. | Kidney graft-infiltrating cells synthesize significantly higher amounts of prostaglandin E2 pre and during acute rejection. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083119 |
| van den Dorpel MA et al. | Beneficial effects of conversion from cyclosporine to azathioprine on fibrinolysis in renal transplant recipients. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083130 |
| Giese A et al. | Thromboxane synthase regulates the migratory phenotype of human glioma cells. | 1999 | Neuro-oncology | pmid:11550298 |
| Licker M et al. | Chronic angiotensin converting inhibition does not influence renal hemodynamic and function during cardiac surgery. | 1999 | Can J Anaesth | pmid:10442956 |
| Miura M and Kurimoto F | [Thromboxane B2 (TXB2)]. | 1999 | Nippon Rinsho | pmid:10635957 |
| Gajdos M et al. | [The effect of monotherapy with ciprofibrate and in combination with acetylsalicylic acid on the spectrum of lipids, thromboxane and fibrinogen in patients with atherosclerosis and hyperlipoproteinemia]. | 1999 | Bratisl Lek Listy | pmid:10645034 |
| Wang S et al. | [Effects of ligustrazine on plasma platelet aggregation rate, thromboxane B2, 6-keto-prostaglandin F1 alpha and von Willebrand's factor in patients with acute onset of cor pulmonale]. | 1999 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11783174 |
| Praticó D et al. | Iron-dependent human platelet activation and hydroxyl radical formation: involvement of protein kinase C. | 1999 | Circulation | pmid:10377074 |
| Carvalho C et al. | A rat model presenting eosinophilia in the airways, lung eosinophil activation, and pulmonary hyperreactivity. | 1999 | Exp. Lung Res. | pmid:10378102 |
| Walsh SW et al. | AA-2414, an antioxidant and thromboxane receptor blocker, completely inhibits peroxide-induced vasoconstriction in the human placenta. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10381779 |
| Sakamoto K et al. | An imbalance in plasma prostanoids in patients with Raynaud's phenomenon and pulmonary vasospasm. | 1999 | Eur. Respir. J. | pmid:10836338 |
| McAdam BF et al. | Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9874808 |
| Fujimoto Y et al. | Sphingomyelin inhibits platelet 12-lipoxygenase activity. | 1999 | Eur. J. Pharmacol. | pmid:10478636 |
| Yang SY and Gao ZX | Determination and clinical significance of plasma levels of prostaglandins in patients with acute brain injury. | 1999 | Surg Neurol | pmid:10511080 |
| Fuglsang J et al. | Intravenous acetylsalicylic acid, magnesium and their combination in experimental arterial thrombosis in rats. | 1999 | Blood Coagul. Fibrinolysis | pmid:10493216 |
| Davì G et al. | In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation. | 1999 | Circulation | pmid:9892587 |
| Nosál R and Jancinová V | Nonreceptor interactions in the pharmacology of blood platelets. | 1999 | Gen. Physiol. Biophys. | pmid:10703730 |
| Jiménez R et al. | Involvement of thromboxane A2 in the endothelium-dependent contractions induced by myricetin in rat isolated aorta. | 1999 | Br. J. Pharmacol. | pmid:10455307 |
| Hino Y et al. | Changes in endothelium-derived vascular regulatory factors during dobutamine-stress-induced silent myocardial ischemia in patients with Kawasaki disease. | 1999 | Jpn. Circ. J. | pmid:10462014 |
| Ogura S et al. | Protective effect of tyrphostin AG-556 on shock induced by endotoxin or gram positive bacteria. | 1999 | Shock | pmid:10446890 |