Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Thromboxane b2?

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Toyofuku T et al. Pulmonary vascular response to platelet-activating factor in conscious sheep. 1988 Am. J. Physiol. pmid:3414811
Utsunomiya T et al. Modification of inflammatory response to aspiration with ibuprofen. 1982 Am. J. Physiol. pmid:6756172
Stephenson AH et al. 5,6-Epoxyeicosatrienoic acid reduces increases in pulmonary vascular resistance in the dog. 1998 Am. J. Physiol. pmid:9688901
Greenberg S et al. Pulmonary vascular smooth muscle function in porcine splanchnic arterial occlusion shock. 1981 Am. J. Physiol. pmid:7246787
Stahl RA et al. Glomerular prostaglandin formation in two-kidney, one-clip hypertensive rats. 1984 Am. J. Physiol. pmid:6507633
Stenmark KR et al. Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension. 1985 Am. J. Physiol. pmid:3923843
Titos E et al. Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4). 1999 Am. J. Physiol. pmid:10564079
Takashio T et al. Inhibitory effect of pindolol on hypoxic pulmonary vasoconstriction. 1992 Am. J. Physiol. pmid:1310232
Sata T et al. Paraquat-induced lung injury: prevention by N-tert-butyl-alpha-phenylnitrone, a free-radical spin-trapping agent. 1992 Am. J. Physiol. pmid:1311515
Addonizio VP et al. Effects of verapamil and diltiazem on human platelet function. 1986 Am. J. Physiol. pmid:3006516
Havill AM et al. alpha-Naphthylthiourea produces dose-dependent lung vascular injury in sheep. 1982 Am. J. Physiol. pmid:6812437
Burch RM and Halushka PV Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells. 1982 Am. J. Physiol. pmid:6816073
Zipser RD Effects of selective inhibition of thromboxane synthesis on renal function in humans. 1985 Am. J. Physiol. pmid:3839111
Stahl RA et al. High protein intake stimulates glomerular prostaglandin formation in remnant kidneys. 1987 Am. J. Physiol. pmid:3473940
Yokoyama Y et al. Role of thromboxane in producing portal hypertension following trauma-hemorrhage. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:14613921
Yokoyama Y et al. Role of thromboxane A2 in early BDL-induced portal hypertension. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12431905
Yang YY et al. Roles of anandamide in the hepatic microcirculation in cirrhotic rats. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16407591
Tanigawa T et al. Anti-inflammatory effect of two isoforms of COX in H. pylori-induced gastritis in mice: possible involvement of PGE2. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12958020
Kleinbongard P et al. Aspirate from human stented native coronary arteries vs. saphenous vein grafts: more endothelin but less particulate debris. 2013 Am. J. Physiol. Heart Circ. Physiol. pmid:23934849
Chen L et al. Cyclooxygenase inhibitor blocks rebound response after NO inhalation in an endotoxin model. 2003 Am. J. Physiol. Heart Circ. Physiol. pmid:12485821
Lombard JH et al. High-salt diet impairs vascular relaxation mechanisms in rat middle cerebral arteries. 2003 Am. J. Physiol. Heart Circ. Physiol. pmid:12456391
Ansari HR et al. Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17921329
Saito Y et al. Disruption of group IVA cytosolic phospholipase A(2) attenuates myocardial ischemia-reperfusion injury partly through inhibition of TNF-α-mediated pathway. 2012 Am. J. Physiol. Heart Circ. Physiol. pmid:22427514
Gendron ME and Thorin E A change in the redox environment and thromboxane A2 production precede endothelial dysfunction in mice. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17644574
Stephenson AH et al. Differential effects of 5,6-EET on segmental pulmonary vasoactivity in the rabbit. 2003 Am. J. Physiol. Heart Circ. Physiol. pmid:12609822
Momen A et al. Local prostaglandin blockade attenuates muscle mechanoreflex-mediated renal vasoconstriction during muscle stretch in humans. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18326807
Cui J et al. Cyclooxygenase inhibition attenuates sympathetic responses to muscle stretch in humans. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18441194
Muscará MN et al. Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10924050
Drew RC et al. Healthy older humans exhibit augmented carotid-cardiac baroreflex sensitivity with aspirin during muscle mechanoreflex and metaboreflex activation. 2015 Am. J. Physiol. Heart Circ. Physiol. pmid:26371168
Jones AE et al. Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat. 2003 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:12639842
Fike CD et al. Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs. 2003 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:12388340
Shinohara M et al. Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1. 2014 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:25217660
Nagase T et al. A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice. 2003 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:12505870
Suliman HB et al. Prevention of influenza-induced lung injury in mice overexpressing extracellular superoxide dismutase. 2001 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:11133496
Nørregaard R et al. Urinary tract obstruction induces transient accumulation of COX-2-derived prostanoids in kidney tissue. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20147610
Venuto R et al. Enhanced vascular effects of the Ca(2+) channel agonist Bay K 8644 in pregnant rabbits. 2002 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:11893597
Yan Q et al. Female ROMK null mice manifest more severe Bartter II phenotype on renal function and higher PGE2 production. 2008 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:18579648
Seta F et al. Renal and cardiovascular characterization of COX-2 knockdown mice. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19357295
Hou X et al. Increased platelet-activating factor-induced periventricular brain microvascular constriction associated with immaturity. 2003 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:12626359
Salazar F et al. Renal effects induced by prolonged mPGES1 inhibition. 2014 Am. J. Physiol. Renal Physiol. pmid:24197070
Llinás MT et al. Role of COX-2-derived metabolites in regulation of the renal hemodynamic response to norepinephrine. 2001 Am. J. Physiol. Renal Physiol. pmid:11592955
Osmond DA et al. Clopidogrel preserves whole kidney autoregulatory behavior in ANG II-induced hypertension. 2014 Am. J. Physiol. Renal Physiol. pmid:24477682
Francois H et al. A role for the thromboxane receptor in L-NAME hypertension. 2008 Am. J. Physiol. Renal Physiol. pmid:18684890
Bautista-Pérez R et al. Involvement of neutral sphingomyelinase in the angiotensin II signaling pathway. 2015 Am. J. Physiol. Renal Physiol. pmid:25354938
Kawada N et al. TP receptors regulate renal hemodynamics during angiotensin II slow pressor response. 2004 Am. J. Physiol. Renal Physiol. pmid:15213069
Edwin SS et al. Cyclosporin A attenuates increased prostaglandin and thromboxane production in response to various stimuli in human decidua. 1993 Sep-Oct Am. J. Reprod. Immunol. pmid:8311924
Badesch DB et al. Decreased arterial wall prostaglandin production in neonatal calves with severe chronic pulmonary hypertension. 1989 Am. J. Respir. Cell Mol. Biol. pmid:2517777
Shellito J and Sniezek M Altered release of eicosanoids by rat alveolar macrophages during granulomatous pulmonary inflammation. 1990 Am. J. Respir. Cell Mol. Biol. pmid:2155633
Dent G et al. Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils. 1998 Am. J. Respir. Cell Mol. Biol. pmid:9448055
Panos RJ et al. Alterations in eicosanoid production by rat alveolar type II cells isolated after silica-induced lung injury. 1992 Am. J. Respir. Cell Mol. Biol. pmid:1312852