Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Adenomatous Polyposis Coli D011125 16 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Lupus Nephritis D008181 8 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Obesity, Morbid D009767 8 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Weil Disease D014895 2 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Sneezing D012912 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Tanus-Santos JE et al. The hemodynamic effects of endothelin receptor antagonism during a venous air infusion in dogs. 2000 Anesth. Analg. pmid:10624986
Praticò D et al. Endogenous biosynthesis of thromboxane and prostacyclin in 2 distinct murine models of atherosclerosis. 2000 Blood pmid:11090066
Heng W et al. [The role of platelet activation in the pathogenesis of asthma]. 2000 Zhonghua Jie He He Hu Xi Za Zhi pmid:11778515
Matsumoto H and Nakao T Elevated urinary excretion of thromboxane B2 in adults with minimal-change nephrotic syndrome. 2000 Clin. Nephrol. pmid:10661487
Leese PT et al. Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: a randomized, controlled trial. 2000 J Clin Pharmacol pmid:10664917
Belton O et al. Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. 2000 Circulation pmid:10952950
Turpeinen AM et al. Similar responses in hemostatic factors after consumption of wholemeal rye bread and low-fiber wheat bread. 2000 Eur J Clin Nutr pmid:10822290
Romano M et al. Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide. 2000 J. Investig. Med. pmid:10822898
Sheu JR et al. Mechanisms involved in the antiplatelet activity of Staphylococcus aureus lipoteichoic acid in human platelets. 2000 Thromb. Haemost. pmid:10823277
Zhou L et al. [The effect of plasma from women with preeclampsia on endothelial cells activators in vitro]. 2000 Zhonghua Fu Chan Ke Za Zhi pmid:11776183
Nosál' R et al. Chloroquine: a multipotent inhibitor of human platelets in vitro. 2000 Thromb. Res. pmid:10828481
Homoncik M et al. Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100. 2000 Thromb. Haemost. pmid:10739392
Schweizer A et al. Aprotinin does not impair renal haemodynamics and function after cardiac surgery. 2000 Br J Anaesth pmid:10740541
Agnoli GC et al. Renal synthesis of prostacyclin and thromboxane in healthy women: differential effects of a short-term saline loading. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780876
Wakitani K et al. JTE-522 selectively inhibits cyclooxygenase-2-derived prostaglandin production in inflammatory tissues. 2000 Inflamm. Res. pmid:10807499
Rilantono LI et al. Dietary antioxidative potential in arteries. 2000 Clin. Hemorheol. Microcirc. pmid:11321428
Liao CH et al. Antiplatelet effect of marchantinquinone, isolated from Reboulia hemisphaerica, in rabbit washed platelets. 2000 J. Pharm. Pharmacol. pmid:10757426
Prieto MA et al. Influence of triflusal on platelet activation after coronary artery bypass graft. 2000 Blood Coagul. Fibrinolysis pmid:10759013
Heller A et al. The complement regulators C1 inhibitor and soluble complement receptor 1 attenuate acute lung injury in rabbits. 2000 Shock pmid:10774617
Semenov AV et al. [Soluble P-selectin - a marker of platelet activation and vessel wall injury: increase of soluble P-selectin in plasma of patients with myocardial infarction, massive atherosclerosis and primary pulmonary hypertension]. 2000 Ter. Arkh. pmid:10833791
Jacobs C et al. 1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase. 2000 J. Med. Chem. pmid:10794700
Patrignani P et al. Effects of vitamin E supplementation on F(2)-isoprostane and thromboxane biosynthesis in healthy cigarette smokers. 2000 Circulation pmid:10920066
Nenci GG and Paliani U [Diabetes, coagulation and vascular events]. 2000 Recenti Prog Med pmid:10748654
Bailey SR et al. Actions and interactions of ADP, 5- HT, histamine and PAF on equine platelets. 2000 Res. Vet. Sci. pmid:10756136
Wang LL et al. Effects of MN-9202 on platelet aggregation, 5-HT release, TXB2 synthesis, and calcium mobilization in rabbit platelets in vitro. 2000 Acta Pharmacol. Sin. pmid:11360670
Basu S et al. Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity. 2000 Clin. Sci. pmid:11099394
Filipov NM et al. Anti-inflammatory effects of ergotamine in steers. 2000 Proc. Soc. Exp. Biol. Med. pmid:11044256
Numminen H et al. The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation. 2000 Stroke pmid:10835443
Kawasaki K et al. Inhibition of 12(S)-hydroxyeicosatetraenoic acid (12-HETE) production suppressed the intimal hyperplasia caused by poor-runoff conditions in the rabbit autologous vein grafts. 2000 J. Cardiovasc. Pharmacol. pmid:11065214
Vazquez-Cruz B et al. Increased renal vasoconstriction and gene expression of cyclooxygenase-1 in renovascular hypertension. 2000 J. Cardiovasc. Pharmacol. pmid:11065217
Greenberg HE et al. A new cyclooxygenase-2 inhibitor, rofecoxib (VIOXX), did not alter the antiplatelet effects of low-dose aspirin in healthy volunteers. 2000 J Clin Pharmacol pmid:11185674
Siler-Khodr TM et al. Effect of ethanol on thromboxane and prostacyclin production in the human placenta. 2000 Alcohol pmid:10963940
Laguna MS et al. [Thromboxane B2 and platelet derived growth factor in essential thrombocythemia treated with anagrelide]. 2000 Medicina (B Aires) pmid:11188949
Matz RL et al. Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids. 2000 Br. J. Pharmacol. pmid:10991924
Tanaka H et al. Effects of milrinone on platelet aggregation in swine with pulmonary hypertension. 2000 J Crit Care pmid:11011824
Cracowski JL et al. Human internal mammary artery contraction by isoprostaglandin f(2alpha) type-III [8-iso-prostaglandin F(2alpha)]. 2000 Eur. J. Pharmacol. pmid:10844110
Coppola A et al. Homocysteine, coagulation, platelet function, and thrombosis. 2000 Semin. Thromb. Hemost. pmid:11011842
Kim WG et al. Is avoidance of air contact necessary for the in vitro evaluation of thrombogenicity in mechanical circulatory assist devices? 2000 Artif Organs pmid:11012543
Kim WG et al. Vasoconstrictive eicosanoid responses to extracorporeal circulation with or without an oxygenator in fetal lambs. 2000 Int J Artif Organs pmid:10941636
Porta C et al. Amifostine, a reactive oxigen species scavenger with radiation- and chemo-protective properties, inhibits in vitro platelet activation induced by ADP, collagen or PAF. 2000 Haematologica pmid:10942928
Krysztopik RJ et al. Lazaroid and pentoxifylline suppress sepsis-induced increases in renal vascular resistance via altered arachidonic acid metabolism. 2000 J. Surg. Res. pmid:10945946
Stanke-Labesque F et al. Angiotensin II-induced contractions in human internal mammary artery: effects of cyclooxygenase and lipoxygenase inhibition. 2000 Cardiovasc. Res. pmid:10946074
Thorwest M et al. Dietary fish oil reduces microvascular thrombosis in a porcine experimental model. 2000 Thromb. Res. pmid:10946095
McCann ME et al. Effect of intravenous infusion of omega-3 and omega-6 lipid emulsions on equine monocyte fatty acid composition and inflammatory mediator production in vitro. 2000 Shock pmid:10947170
Kamata K et al. Altered endothelium-dependent and -independent hyperpolarization and endothelium-dependent relaxation in carotid arteries isolated from streptozotocin-induced diabetic rats. 2000 Naunyn Schmiedebergs Arch. Pharmacol. pmid:10935533
Li JB et al. [A further research on physiopathological basis of "Liver Yang Forming Wind Syndrome"]. 2000 Hunan Yi Ke Da Xue Xue Bao pmid:12205996
Ohata T et al. Role of nitric oxide in a temperature dependent regulation of systemic vascular resistance in cardiopulmonary bypass. 2000 Eur J Cardiothorac Surg pmid:10973545
Togna GI et al. Cisplatin triggers platelet activation. 2000 Thromb. Res. pmid:10973681
Yuk DY et al. Antithrombotic and antiplatelet activities of 2-chloro-3-[4-(ethylcarboxy)-phenyl]-amino-1,4-naphthoquinone (NQ12), a newly synthesized 1,4-naphthoquinone derivative. 2000 Biochem. Pharmacol. pmid:10974210
Moosig F et al. Opsonization of apoptotic neutrophils by anti-neutrophil cytoplasmic antibodies (ANCA) leads to enhanced uptake by macrophages and increased release of tumour necrosis factor-alpha (TNF-alpha). 2000 Clin. Exp. Immunol. pmid:11122261
Bereczki C et al. The roles of platelet function, thromboxane, blood lipids and nitric oxide in hypertension of children and adolescents. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10883060
Carty E et al. Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. 2000 Aliment. Pharmacol. Ther. pmid:10848666
Dschietzig T et al. Stimulation of pulmonary big endothelin-1 and endothelin-1 by antithrombin III: a rationale for combined application of antithrombin III and endothelin antagonists in sepsis-related acute respiratory distress syndrome? 2000 Crit. Care Med. pmid:10921577
Muscará MN et al. Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10924050
Mizugaki M [Microdetermination of eicosanoids using mass spectrometry]. 2000 Nippon Yakurigaku Zasshi pmid:10876809
Depré M et al. Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans. 2000 Eur. J. Clin. Pharmacol. pmid:10877012
Theriot JA et al. Dietary chloride does not correlate with urinary thromboxane in deoxycorticosterone acetate-treated rats. 2000 J. Lab. Clin. Med. pmid:10850649
Kowalska MA et al. Stromal cell-derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets. 2000 Blood pmid:10891429
Bailey SR et al. Differential activation of platelets from normal and allergic ponies by PAF and ADP. 2000 Inflamm. Res. pmid:10893045
Rao AR and Prabhakar MC Screening methods for antiasthmatic agents. 2000 Methods Find Exp Clin Pharmacol pmid:10893704
Cayatte AJ et al. The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo E-deficient mice: evidence that eicosanoids other than thromboxane contribute to atherosclerosis. 2000 Arterioscler. Thromb. Vasc. Biol. pmid:10894809
Pärsson HN et al. Maintaining carotid flow by shunting during carotid endarterectomy diminishes the inflammatory response mediating ischaemic brain injury. 2000 Eur J Vasc Endovasc Surg pmid:10727360
Okada S et al. Perfusion of the hypothalamic paraventricular nucleus with N-methyl-D-aspartate produces thromboxane A2 and centrally activates adrenomedullary outflow in rats. 2000 Neuroscience pmid:10717438
Zaitsu M et al. Ulinastatin, an elastase inhibitor, inhibits the increased mRNA expression of prostaglandin H2 synthase-type 2 in Kawasaki disease. 2000 J. Infect. Dis. pmid:10720537
De La Cruz JP et al. Effect of DT-TX 30, a combined thromboxane synthase inhibitor and thromboxane receptor antagonist, on retinal vascularity in experimental diabetes mellitus. 2000 Thromb. Res. pmid:10680643
Nagano K et al. Prostanoids regulate proliferation of vascular smooth muscle cells induced by arginine vasopressin. 2000 Eur. J. Pharmacol. pmid:10686292
Tegeder I et al. Effects of selective and unselective cyclooxygenase inhibitors on prostanoid release from various rat organs. 2000 J. Pharmacol. Exp. Ther. pmid:10688636
Tran HS et al. The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock. 2000 Shock pmid:10847636
Maccarrone M et al. Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells. 2000 Biochem. Biophys. Res. Commun. pmid:10833416
Gardan B et al. Vasoconstrictor effects of iso-prostaglandin F2alpha type-III (8-iso-prostaglandin F2alpha) on human saphenous veins. 2000 J. Cardiovasc. Pharmacol. pmid:10813374
Suntres ZE and Shek PN Prophylaxis against lipopolysaccharide-induced lung injuries by liposome-entrapped dexamethasone in rats. 2000 Biochem. Pharmacol. pmid:10704946
Giedrojć J et al. [Interaction of platelets with monocytes with regard to arachidonic acid metabolites]. 2000 Prz. Lek. pmid:11199865
Ames PR et al. Antioxidant susceptibility of pathogenic pathways in subjects with antiphospholipid antibodies: a pilot study. 2000 Lupus pmid:11199924
Wang ZG et al. Can endothelial seeding enhance patency and inhibit neointimal hyperplasia? Experimental studies and clinical trial of endothelial seeded venous prostheses. 2000 Int Angiol pmid:11201596
MacKay RJ et al. Effect of eltenac in horses with induced endotoxaemia. 2000 Equine Vet J Suppl pmid:11202378
de la Riva IJ et al. Effect of oral L-arginine administration for three weeks in two kidney-two clip hypertensive rats. 2000 Arch. Physiol. Biochem. pmid:11262599
Cryer B et al. Effects of cutaneous aspirin on the human stomach and duodenum. 1999 Sep-Oct Proc. Assoc. Am. Physicians pmid:10519166
Stewart KG et al. Estrogen decreases prostaglandin H synthase products from endothelial cells. 1999 Nov-Dec J. Soc. Gynecol. Investig. pmid:10643586
Tong H et al. Prostaglandin endoperoxide synthase-2 abundance is increased in brain tissues of late-gestation fetal sheep in response to cerebral hypoperfusion. 1999 May-Jun J. Soc. Gynecol. Investig. pmid:10376268
Uriu K et al. Effect of acute thromboxane A2 inhibition on the renal hemodynamics in a spontaneously non-insulin-dependent diabetic rat, Otsuka Long-Evans Tokushima Fatty rat. 1999 Jul-Aug J. Diabetes Complicat. pmid:10616856
Pestana M et al. Kidney graft-infiltrating cells synthesize significantly higher amounts of prostaglandin E2 pre and during acute rejection. 1999 Feb-Mar Transplant. Proc. pmid:10083119
van den Dorpel MA et al. Beneficial effects of conversion from cyclosporine to azathioprine on fibrinolysis in renal transplant recipients. 1999 Feb-Mar Transplant. Proc. pmid:10083130
Williams CA et al. The flavonoids of Tanacetum parthenium and T. vulgare and their anti-inflammatory properties. 1999 Phytochemistry pmid:10382317
Arons MM et al. Effects of ibuprofen on the physiology and survival of hypothermic sepsis. Ibuprofen in Sepsis Study Group. 1999 Crit. Care Med. pmid:10321658
Titos E et al. Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4). 1999 Am. J. Physiol. pmid:10564079
Reis F et al. The peripheral serotonergic system and platelet aggregation in cyclosporin A-induced hypertensive rats. 1999 Thromb. Res. pmid:10605951
Eldor A et al. A chronic hypercoagulable state in patients with beta-thalassaemia major is already present in childhood. 1999 Br. J. Haematol. pmid:10606878
Kubo K et al. A 21-aminosteroid, U-74006F, attenuates endotoxin-induced lung injury in awake sheep. 1999 Respirology pmid:10382236
Shen AY et al. Inhibition of 2-P-mercaptophenyl-1,4-naphthoquinone on human platelet function. 1999 Life Sci. pmid:10403492
Jönsson A et al. Effects of amide local anaesthetics on eicosanoid formation in burned skin. 1999 Acta Anaesthesiol Scand pmid:10408815
Braun-Dullaeus RC et al. Cyclosporine-induced coronary artery constriction--dissociation between thromboxane release and coronary vasospasm. 1999 J. Heart Lung Transplant. pmid:10226897
Kanji VK et al. Vitamin E suppresses cyclosporine A-induced increase in the urinary excretion of arachidonic acid metabolites including F2-isoprostanes in the rat model. 1999 Transplant. Proc. pmid:10331052
Mita H et al. Generation of thromboxane A2 from highly purified human sinus mast cells after immunological stimulation. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10359019
Denizot Y et al. Are lipid mediators implicated in the production of pro- and anti-inflammatory cytokines during cardiopulmonary bypass graft with extracorporeal circulation? 1999 Cytokine pmid:10328869
Gurbel PA et al. Plasma thromboxane and prostacyclin are linear related and increased in patients presenting with acute myocardial infarction. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10477035
Li D et al. The association of diet and thrombotic risk factors in healthy male vegetarians and meat-eaters. 1999 Eur J Clin Nutr pmid:10477247
McCowan LM et al. Administration of low-dose aspirin to mothers with small for gestational age fetuses and abnormal umbilical Doppler studies to increase birthweight: a randomised double-blind controlled trial. 1999 Br J Obstet Gynaecol pmid:10428519
Dickneite G and Leithäuser B Influence of antithrombin III on coagulation and inflammation in porcine septic shock. 1999 Arterioscler. Thromb. Vasc. Biol. pmid:10364091
Spokas EG et al. Whole-blood assays for evaluation of thromboxane synthase inhibition. 1999 Methods Mol. Biol. pmid:10343321
Bode AP et al. Activation and adherence of lyophilized human platelets on canine vessel strips in the Baumgartner perfusion chamber. 1999 J. Lab. Clin. Med. pmid:9989772