| MeSH term | MeSH ID | Detail |
|---|---|---|
| Helicobacter Infections | D016481 | 21 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Embolism, Fat | D004620 | 4 associated lipids |
| Polycystic Kidney Diseases | D007690 | 12 associated lipids |
| Heart Septal Defects | D006343 | 2 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Pneumonia, Viral | D011024 | 3 associated lipids |
| Intermittent Claudication | D007383 | 6 associated lipids |
| Aortic Aneurysm | D001014 | 8 associated lipids |
| Hydatidiform Mole | D006828 | 3 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Deimann W et al. | Endogenous peroxidase in the nuclear envelope and endoplasmic reticulum of human monocytes in vitro: association with arachidonic acid metabolism. | 1984 | Blood | pmid:6331550 |
| Irvine RF et al. | One-dimensional thin-layer chromatographic separation of the lipids involved in arachidonic acid metabolism. | 1984 | J Pharmacol Methods | pmid:6443136 |
| Rainsford KD et al. | Comparative effects of some non-steroidal anti-inflammatory drugs on the ultrastructural integrity and prostaglandin levels in the rat gastric mucosa: relationship to drug uptake. | 1984 | Scand. J. Gastroenterol. Suppl. | pmid:6443622 |
| Wada H et al. | Effect of TEI-4120 (3-benzoyl-N-beta-ethoxyisopropyl-2-methlindole) on carrageenan induced disseminated intravascular coagulation (DIC) in rats. | 1984 | J. Pharmacobio-dyn. | pmid:6548260 |
| Johnston C et al. | Prostacyclin and thromboxane in non-insulin dependent diabetes: the chlorpropamide alcohol flush reaction revisited. | 1984 | Clin. Sci. | pmid:6548428 |
| Nicod P et al. | Acute systemic and coronary hemodynamic and serologic responses to cigarette smoking in long-term smokers with atherosclerotic coronary artery disease. | 1984 | J. Am. Coll. Cardiol. | pmid:6548482 |
| Welton AF et al. | Ro 22-3747: a new antiallergic agent for the treatment of immediate hypersensitivity diseases. | 1984 | J. Pharmacol. Exp. Ther. | pmid:6198511 |
| Stegmeier K et al. | The pharmacological profile of the thromboxane A2 antagonist BM 13.177. A new anti-platelet and anti-thrombotic drug. | 1984 | Thromb. Res. | pmid:6385334 |
| Ritter JM | Prostanoid synthesis by aortic rings in human blood: selective increase of prostacyclin mediated by a serum factor. | 1984 | Br. J. Pharmacol. | pmid:6386089 |
| Vicenzi E et al. | Human mononuclear phagocytes from different anatomical sites differ in their capacity to metabolize arachidonic acid. | 1984 | Clin. Exp. Immunol. | pmid:6432383 |
| Schneidkraut MJ et al. | Thromboxane and prostacyclin synthesis following whole body irradiation in rats. | 1984 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6386769 |
| Puustinen T et al. | Glucocorticoids do not decrease thromboxane and prostacyclin levels in human blood. | 1984 | Prostaglandins Leukot Med | pmid:6387721 |
| Sekiya K and Okuda H | Inhibitory action of soluble elastin on thromboxane B2 formation in blood platelets. | 1984 | Biochim. Biophys. Acta | pmid:6320905 |
| Wang JP et al. | Antiplatelet effect of capsaicin. | 1984 | Thromb. Res. | pmid:6528310 |
| Sedor JR et al. | Effects of sulindac and indomethacin on renal prostaglandin synthesis. | 1984 | Clin. Pharmacol. Ther. | pmid:6428794 |
| Goodman MG and Weigle WO | Regulation of B-lymphocyte proliferative responses by arachidonate metabolites: effects on membrane-directed versus intracellular activators. | 1984 | J. Allergy Clin. Immunol. | pmid:6432883 |
| Lampugnani MG and de Gaetano G | Effects of metabolized and unmetabolized arachidonate on rat platelet shape change. | 1984 | Am. J. Physiol. | pmid:6433724 |
| Goldyne ME | Heterogeneity in leukocyte preparations: effects on defining eicosanoid metabolism by human lymphocytes and monocytes. | 1984 | J. Allergy Clin. Immunol. | pmid:6088610 |
| Roth DM et al. | Effects of lipoxygenase inhibitors in arachidonate-induced sudden death. | 1984 | J. Pharm. Pharmacol. | pmid:6144761 |
| Worthington RE and Fuller GC | Dibutyryl cyclic guanosine monophosphate elevates bovine endothelial cell thromboxane production without affecting prostacyclin metabolism. | 1984 | Thromb. Res. | pmid:6322377 |
| Foegh ML et al. | Urine thromboxane as an immunologic monitor in kidney transplant patients. | 1984 | Transplant. Proc. | pmid:6390872 |
| Crutchley DJ | Effects of inhibitors of arachidonic acid metabolism on thromboplastin activity in human monocytes. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6422935 |
| DeRubertis FR et al. | Bile salt stimulation of colonic epithelial proliferation. Evidence for involvement of lipoxygenase products. | 1984 | J. Clin. Invest. | pmid:6438153 |
| Zipser RD and Smorlesi C | Regulation of urinary thromboxane B2 in man: influence of urinary flow rate and tubular transport. | 1984 | Prostaglandins | pmid:6718753 |
| Kutti J et al. | The effect of acetylsalicylic acid in 3 different formulations on in vitro and in vivo platelet function tests. An experimental study on healthy male volunteers. | 1984 | Scand J Haematol | pmid:6719042 |
| Holme S et al. | The effect of albumin bound polyunsaturated fatty acids on human platelets. | 1984 | Thromb. Haemost. | pmid:6719386 |
| Marks JG et al. | Contact urticaria and airway obstruction from carbonless copy paper. | 1984 Aug 24-31 | JAMA | pmid:6235381 |
| MacNab MW et al. | The effects of a new thromboxane synthetase inhibitor, CGS-13080, in man. | 1984 Feb-Mar | J Clin Pharmacol | pmid:6371062 |
| Buchanan MR and Hirsh J | Effect of aspirin and salicylate on platelet-vessel wall interactions in rabbits. | 1984 Jul-Aug | Arteriosclerosis | pmid:6380468 |
| Paajanen H et al. | Modification of platelet aggregation and thromboxane synthesis by intravascular contrast media. | 1984 Jul-Aug | Invest Radiol | pmid:6434489 |
| De Caterina R et al. | Thromboxane-B2 generation during ex-vivo platelet aggregation. | 1984 Jul-Sep | J. Nucl. Med. Allied Sci. | pmid:6530623 |
| Egg D | Concentrations of prostaglandins D2, E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 in synovial fluid from patients with inflammatory joint disorders and osteoarthritis. | 1984 Mar-Apr | Z Rheumatol | pmid:6730731 |
| Tanabe M et al. | Inhibition of coronary circulatory failure and thromboxane A2 release during coronary occlusion and reperfusion by 2-phenylaminoadenosine (CV-1808) in anesthetized dogs. | 1984 May-Jun | J. Cardiovasc. Pharmacol. | pmid:6202970 |
| Laustiola K et al. | Exercise-induced increase in plasma arachidonic acid and thromboxane B2 in healthy men: effect of beta-adrenergic blockade. | 1984 May-Jun | J. Cardiovasc. Pharmacol. | pmid:6202971 |
| Sturm M et al. | The measurement of plasma thromboxane B2 and the effect of smoking. | 1984 Nov-Dec | Clin. Exp. Pharmacol. Physiol. | pmid:6536421 |
| Menitove JE et al. | Use of prostacyclin to inhibit activation of platelets during preparation of platelet concentrates. | 1984 Nov-Dec | Transfusion | pmid:6390814 |
| Fisher M et al. | Selective thromboxane inhibition: a new approach to antiplatelet therapy. | 1984 Sep-Oct | Stroke | pmid:6474531 |
| Uderman HD et al. | Thromboxane synthetase inhibitor UK38,485 lowers blood pressure in the adult spontaneously hypertensive rat. | 1984 Sep-Oct | J. Cardiovasc. Pharmacol. | pmid:6209508 |
| Greer IA et al. | Inhibition of thromboxane and prostacyclin production in whole blood by adrenoceptor antagonists. | 1985 | Prostaglandins Leukot Med | pmid:2865745 |
| Mikhailidis DP et al. | The effect of non-specific beta-blockade on metabolic and haemostatic variables during hypoglycaemia. | 1985 | Diabetes Res. | pmid:2866057 |
| Mehta J et al. | Increase in human platelet alpha 2-adrenergic receptor affinity for agonist in unstable angina. | 1985 | J. Lab. Clin. Med. | pmid:2866219 |
| Greer IA et al. | A comparative study of the effects of adrenoceptor antagonists on platelet aggregation and thromboxane generation. | 1985 | Thromb. Haemost. | pmid:2867620 |
| Gragnoli G et al. | Effects of somatostatin on the behaviour of thromboxane B2 and beta-thromboglobulin in type I diabetes. | 1985 | Acta Endocrinol. | pmid:2408435 |
| Yardumian DA et al. | Platelet hyperaggregability occurring during prolonged continuous intravenous infusions of prostacyclin analogue ZK 36374. | 1985 | Br. J. Haematol. | pmid:2408653 |
| Patrassi GM et al. | Contact phase of coagulation in diabetes mellitus after aspirin administration. | 1985 | Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. | pmid:2410343 |
| Brown EM and Swartz SL | Production of prostaglandins by dispersed cells and fragments from bovine parathyroid glands. | 1985 | Prostaglandins | pmid:3883430 |
| Boraschi D et al. | Regulation of arachidonic acid metabolism in macrophages by immune and nonimmune interferons. | 1985 | J. Immunol. | pmid:3923110 |
| Walsh SW | Preeclampsia: an imbalance in placental prostacyclin and thromboxane production. | 1985 | Am. J. Obstet. Gynecol. | pmid:3923838 |
| Stenmark KR et al. | Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension. | 1985 | Am. J. Physiol. | pmid:3923843 |
| Quilley J and McGiff JC | Arachidonic acid metabolism and urinary excretion of prostaglandins and thromboxane in rats with experimental diabetes mellitus. | 1985 | J. Pharmacol. Exp. Ther. | pmid:3925127 |
| Mobley A and Tai HH | Synergistic stimulation of thromboxane biosynthesis by calcium ionophore and phorbol ester or thrombin in human platelets. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3927908 |
| Jakubowski JA et al. | Cumulative antiplatelet effect of low-dose enteric coated aspirin. | 1985 | Br. J. Haematol. | pmid:3927970 |
| Mehta J et al. | Influence of selective thromboxane synthetase blocker CGS-13080 on thromboxane and prostacyclin biosynthesis in whole blood: evidence for synthesis of prostacyclin by leukocytes from platelet-derived endoperoxides. | 1985 | J. Lab. Clin. Med. | pmid:3928780 |
| Sawada M et al. | Enzyme-immunoassay of thromboxane B2 at the picogram level. | 1985 | Prostaglandins | pmid:3929333 |
| De Caterina R et al. | Low-dose aspirin in patients recovering from myocardial infarction. Evidence for a selective inhibition of thromboxane-related platelet function. | 1985 | Eur. Heart J. | pmid:3930246 |
| Fukuda Y | [Plasma prostaglandin and thromboxane levels in asthmatic children]. | 1985 | Arerugi | pmid:2992423 |
| Honda M et al. | Effects of purified hog pancreatic kallikrein on the kinin-prostaglandin system and renin-angiotensin-aldosterone system. | 1985 | Nephron | pmid:2993934 |
| Mehta P et al. | Plasma concentrations of thromboxane and prostacyclin metabolites in patients with bone tumors. | 1985 | Am J Pediatr Hematol Oncol | pmid:2994511 |
| Benigni A et al. | Inhibition of human platelet aggregation by parathyroid hormone. Is cyclic AMP implicated? | 1985 | Am. J. Nephrol. | pmid:2996352 |
| Mitchell JA et al. | Effects of high frequency oscillatory ventilation compared to conventional ventilation upon pulmonary vascular prostanoid production in neonatal piglets. | 1985 | Prostaglandins Leukot Med | pmid:3883366 |
| Wang JP et al. | Antiplatelet effect of hsien-ho-t'sao (Agrimonia pilosa). | 1985 | Am. J. Chin. Med. | pmid:3927704 |
| Wenger H et al. | Pulmonary dysfunction secondary to soft-tissue endotoxin. | 1985 | Arch Surg | pmid:3883949 |
| Hashimoto Y et al. | Time-dependent inhibition of the cyclooxygenase pathway by 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3927909 |
| Meyrick B et al. | Endothelial prostacyclin production is a late event in granulocyte migration into bovine pulmonary artery intimal explants. | 1985 | Blood | pmid:3904871 |
| Túri S et al. | [Changes in serum prostaglandin metabolites in Schönlein-Henoch purpura]. | 1985 | Orv Hetil | pmid:3897944 |
| Farias LR et al. | Effect of prostaglandin blockers on ascites fluid in pancreatitis. | 1985 | Surgery | pmid:3898455 |
| Kubo K and Kobayashi T | Effects of OKY-046, a selective thromboxane synthetase inhibitor, on endotoxin-induced lung injury in unanesthetized sheep. | 1985 | Am. Rev. Respir. Dis. | pmid:3898941 |
| Barst RJ and Stalcup SA | Endothelial function in clinical pulmonary hypertension. | 1985 | Chest | pmid:3899537 |
| Pedersen AK and FitzGerald GA | Cyclooxygenase inhibition, platelet function, and metabolite formation during chronic sulfinpyrazone dosing. | 1985 | Clin. Pharmacol. Ther. | pmid:3917387 |
| Pediconi M et al. | Effects of acute and chronic ethanol administration on thromboxane and prostacyclin levels and release in rat brain cortex. | 1985 | Prostaglandins | pmid:3901122 |
| Neri Serneri GG et al. | Abnormal cardiocoronary thromboxane A2 production in patients with unstable angina. | 1985 | Am. Heart J. | pmid:3984828 |
| Barst RJ et al. | Relation of arachidonate metabolites to abnormal control of the pulmonary circulation in a child. | 1985 | Am. Rev. Respir. Dis. | pmid:3917630 |
| Halenda SP et al. | Phorbol esters and oleoyl acetoyl glycerol enhance release of arachidonic acid in platelets stimulated by Ca2+ ionophore A23187. | 1985 | J. Biol. Chem. | pmid:3930496 |
| Zahavi J and Zahavi M | Enhanced platelet release reaction, shortened platelet survival time and increased platelet aggregation and plasma thromboxane B2 in chronic obstructive arterial disease. | 1985 | Thromb. Haemost. | pmid:3158092 |
| Roy L et al. | Lack of efficacy of nafazatrom, a novel anti-thrombotic compound, in patients with coronary artery disease. | 1985 | Am. Heart J. | pmid:3158183 |
| Reines HD et al. | Dazoxiben in human sepsis and adult respiratory distress syndrome. | 1985 | Clin. Pharmacol. Ther. | pmid:3979000 |
| Greco NJ et al. | Action of platelet-activating factor on type 1 diabetic human platelets. | 1985 | J. Lab. Clin. Med. | pmid:3981054 |
| Patterson GA et al. | Effects of imidazole and indomethacin on fluid balance in isolated sheep lungs. | 1985 | J. Appl. Physiol. | pmid:3884582 |
| Prosdocimi M et al. | Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog. | 1985 | Am. J. Physiol. | pmid:3838623 |
| Krieger BP et al. | Mechanisms of interaction between oxygen and granulocytes in hyperoxic lung injury. | 1985 | J. Appl. Physiol. | pmid:3838744 |
| Valentovic MA and Lubawy WC | Elevated glucose in vivo and in vitro adversely alters prostaglandin generation in rat aortas and platelets. | 1985 | Prostaglandins Leukot Med | pmid:3903777 |
| Bergqvist D et al. | The effect of inhibition of thromboxane synthesis in experimental thrombosis and hemostasis. | 1985 | Thromb. Res. | pmid:3838828 |
| Stuart MJ et al. | Prostanoids in hemolytic uremic syndrome. | 1985 | J. Pediatr. | pmid:3839015 |
| Nigam S et al. | The concentrations of 6-keto-PGF1 alpha and TXB2 in plasma samples from patients with benign and malignant tumours of the breast. | 1985 | Prostaglandins | pmid:3839084 |
| Petroni A et al. | Differential effects of various vasoactive drugs on basal and stimulated levels of TXB2 and 6-keto-PGF1 alpha in rat brain. | 1985 | Prostaglandins | pmid:3839085 |
| Mendieta CF et al. | Biosynthesis of prostaglandins in gingiva of patients with chronic periodontitis. | 1985 | J. Periodontol. | pmid:3919173 |
| Haurand M and Ullrich V | Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P-450 enzyme. | 1985 | J. Biol. Chem. | pmid:2999104 |
| Chang J et al. | Modulation by hydroxyeicosatetraenoic acids (HETEs) of arachidonic acid metabolism in mouse resident peritoneal macrophages. | 1985 | Eur. J. Pharmacol. | pmid:3920057 |
| Hillbom M et al. | Platelet thromboxane formation and bleeding time is influenced by ethanol withdrawal but not by cigarette smoking. | 1985 | Thromb. Haemost. | pmid:4049313 |
| Aviram M et al. | Plasma lipoproteins affect platelet malondialdehyde and thromboxane B2 production. | 1985 | Biochem Med | pmid:4052061 |
| Simmet T et al. | Modulation of eicosanoid release from anaphylactic guinea-pig heart with 5-benzoyl-a-methyl-2-thiophene acetic acid (tiaprofenic acid). | 1985 | Arch Int Pharmacodyn Ther | pmid:3841634 |
| Rinaldo JE and Dauber JH | Effect of methylprednisolone and of ibuprofen, a nonsteroidal antiinflammatory agent, on bronchoalveolar inflammation following endotoxemia. | 1985 | Circ. Shock | pmid:4053294 |
| Shingu T | [Prostaglandin metabolism in ischemic brain edema]. | 1985 | Nihon Geka Hokan | pmid:3841635 |
| Leffler CW and Busija DW | Prostanoids in cortical subarachnoid cerebrospinal fluid and pial arterial diameter in newborn pigs. | 1985 | Circ. Res. | pmid:4053302 |
| Shohami E and Gross J | An ex vivo method for evaluating prostaglandin synthetase activity in cortical slices of mouse brain. | 1985 | J. Neurochem. | pmid:3923156 |
| Tobian L et al. | Prostaglandin alterations in barely hypertensive Dahl S rats. | 1985 | Trans. Assoc. Am. Physicians | pmid:3842205 |
| Numano F et al. | Coronary spasm, prostaglandin and HLA factors. | 1985 | Jpn. Circ. J. | pmid:3855470 |
| Purkerson ML et al. | Inhibition of thromboxane synthesis ameliorates the progressive kidney disease of rats with subtotal renal ablation. | 1985 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3855542 |
| Dahl ML and Uotila P | Sodium salicylate does not prevent the inhibitory effect of indomethacin on thromboxane formation in human blood ex vivo. | 1985 | Prostaglandins Leukot Med | pmid:3856282 |
| Sterk PJ et al. | Limited maximal airway narrowing in nonasthmatic subjects. Role of neural control and prostaglandin release. | 1985 | Am. Rev. Respir. Dis. | pmid:2864892 |