Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Helicobacter Infections D016481 21 associated lipids
Infertility D007246 3 associated lipids
Embolism, Fat D004620 4 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Heart Septal Defects D006343 2 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Intermittent Claudication D007383 6 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Ahlsten G et al. Aggregation of and thromboxane B2 synthesis in platelets from newborn infants of smoking and non-smoking mothers. 1985 Prostaglandins Leukot Med pmid:3863152
Rosenkranz B and Frölich JC Plasma concentrations and anti-platelet effects after low dose acetylsalicylic acid. 1985 Prostaglandins Leukot Med pmid:3864170
Durante W and Sunahara FA Cardiovascular effects of high frequency ventilation--the possible involvement of thromboxane. 1987 Prostaglandins Leukot Med pmid:3114767
Hamasaki Y et al. Hypoxia stimulates prostacyclin generation by dog lung in vitro. 1982 Prostaglandins Leukot Med pmid:7051045
Hall ER et al. Monoclonal antibody against TXB2: its use in solid and liquid phase radioimmunoassays. 1987 Prostaglandins Leukot Med pmid:3423097
Karmali RA et al. Prostaglandin regulation of murine mammary tumor virus production: a basis for some of the glucocorticoid and prolactin actions on mammary tumor cell cultures. 1982 Prostaglandins Leukot Med pmid:6296884
Merola AJ et al. Prostaglandin response in the exercise conditioned rat. 1984 Prostaglandins Leukot Med pmid:6377328
Puustinen T et al. Glucocorticoids do not decrease thromboxane and prostacyclin levels in human blood. 1984 Prostaglandins Leukot Med pmid:6387721
Kazama Y et al. Reevaluation of circulating prostacyclin and thromboxane in diabetes. 1987 Prostaglandins Leukot Med pmid:3550820
Sinzinger H et al. Platelet function and prostaglandins in patients with peripheral vascular disease treated with calcium dobesilate. 1987 Prostaglandins Leukot Med pmid:2959967
Pullen RH et al. High performance liquid chromatographic determination of thromboxane B2 in human serum as a methoxime-panacylester derivative. 1987 Prostaglandins Leukot Med pmid:3432306
Reeves WC et al. The release of thromboxane A2 and prostacyclin following experimental acute pulmonary embolism. 1983 Prostaglandins Leukot Med pmid:6348800
Mehta P et al. Thromboxane and prostacyclin generation by intact human vessels in response to balloon catheter trauma. 1982 Prostaglandins Leukot Med pmid:6217465
Kaar ML et al. Prostacyclin and thromboxane in diabetic children. 1983 Prostaglandins Leukot Med pmid:6351104
Zavagli G et al. Platelet aggregation and evaluation of the ratio thromboxane B2/6-keto-prostaglandin F1 alpha in the plasma of patients on long term cimetidine treatment. 1985 Prostaglandins Leukot Med pmid:2997804
Tremoli E et al. In vitro effects of aspirin and non steroidal anti-inflammatory drugs on the formation of 12-hydroxyeicosatetraenoic acid by platelets. 1986 Prostaglandins Leukot Med pmid:3094026
McDonald JW and Ali M Recovery of cyclooxygenase activity after aspirin in populations of platelets separated on stractan density gradients. 1983 Prostaglandins Leukot Med pmid:6419234
Simberg N Maternal aspirin administration inhibits pulmonary arachidonic acid metabolism in fetal rabbits. 1984 Prostaglandins Leukot Med pmid:6425868
Rao GH et al. Enteric-coated aspirin, platelet cyclooxygenase activity and function. 1984 Prostaglandins Leukot Med pmid:6425869
Al-Hassan JM et al. Prostaglandin associated mortality following intravenous injection of catfish epidermal secretions in rabbits. 1987 Prostaglandins Leukot Med pmid:3475731
Brandt R et al. Effect of propranolol, practolol and atenolol on human platelet thromboxane formation and plasma levels of prostaglandins 6-keto-F1 alpha and E2. 1984 Prostaglandins Leukot Med pmid:6597450
Chiba S et al. Sex and age-related differences in the urinary excretion of TXB2 in normal human subjects: a possible pathophysiological role of TXA2 in the aged kidney. 1984 Prostaglandins Leukot Med pmid:6597456
Mahmud I et al. Thromboxane synthesizing system in rat liver. 1984 Prostaglandins Leukot Med pmid:6597457
Pönicke K et al. Stimulation of aggregation and thromboxane A2 formation of human platelets by hypoxia. 1987 Prostaglandins Leukot Med pmid:3478738
Henriksson P et al. Increased aortic thromboxane production in experimental atherosclerosis. 1987 Prostaglandins Leukot Med pmid:3478739
Ouwendijk RJ et al. Raised plasma thromboxane B2 levels in alcoholic liver disease. 1983 Prostaglandins Leukot Med pmid:6573682
Hornych A et al. Thromboxane B2 in borderline and essential hypertensive patients. 1983 Prostaglandins Leukot Med pmid:6573683
Wilson L and Lindsey R Effects of progesterone withdrawal on uterine prostaglandin levels in the ovariectomized pregnant rat. 1987 Prostaglandins Leukot Med pmid:3478741
Semrad SD and Moore JN Effects of multiple low doses of flunixin meglumine on repeated endotoxin challenge in the horse. 1987 Prostaglandins Leukot Med pmid:3303061
Flynn JT et al. Effects of anesthesia and surgery on prostanoid concentrations in plasma and pulmonary lymph. 1983 Prostaglandins Leukot Med pmid:6573688
Patel K and Bakhle YS Thromboxane B2 (TxB2) metabolism in rat isolated lung and its inhibition by drugs. 1983 Prostaglandins Leukot Med pmid:6573689
Davì G et al. Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients. 1983 Prostaglandins Leukot Med pmid:6573692
Lieb J et al. Elevated levels of prostaglandin E2 and thromboxane B2 in depression. 1983 Prostaglandins Leukot Med pmid:6574523
Viinikka L et al. Effect of prolonged treatment with acetylsalicylic acid and dipyridamole on platelet thromboxane A2 production in atherosclerotic subjects. 1983 Prostaglandins Leukot Med pmid:6576385
Fukumoto S and Tanaka K Protective effects of thromboxane A2 synthetase inhibitors on endotoxin shock. 1983 Prostaglandins Leukot Med pmid:6576388
Kinney EL et al. Mechanism of action of amrinone: role of thromboxane synthetase inhibition. 1983 Prostaglandins Leukot Med pmid:6576389
Giani E et al. Platelets from aged rats aggregate more, but are more sensitive to prostacyclin. 1985 Prostaglandins Leukot Med pmid:3003760
Hutchison AA et al. Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates. 1985 Prostaglandins Leukot Med pmid:3859877
Mahmoud TZ et al. Correlation between umbilical artery resistance index, 6 ketoprostaglandin F1 alpha and thromboxane B2 in the fetoplacental compartment in patients with pregnancy induced hypertension. 1993 Prostaglandins pmid:8337411
Bjøro K et al. Formation of prostanoids in human umbilical vessels perfused in vitro. 1986 Prostaglandins pmid:3523623
Lagente V et al. Interference of the PAF-acether antagonist BN 52021 with passive anaphylaxis in the guinea-pig. 1987 Prostaglandins pmid:2438723
Bjøro K Prostacyclin and thromboxane formation in human umbilical arteries following stimulation with vasoactive autacoids. 1986 Prostaglandins pmid:3523624
Leach CM and Thorburn GD A comparative study of collagen induced thromboxane release from platelets of different species: implications for human atherosclerosis models. 1982 Prostaglandins pmid:7122912
Giani E et al. Sex differences in platelet thromboxane and arterial prostacyclin production in control and n-6 fatty acid supplemented rats. 1984 Prostaglandins pmid:6441187
Vesterqvist O and Gréen K Urinary excretion of 2,3-dinor-thromboxane B2 in man under normal conditions, following drugs and during some pathological conditions. 1984 Prostaglandins pmid:6539491
Murota S and Morita I Effect of prostaglandin I2 and related compounds on vascular permeability response in granuloma tissues. 1978 Prostaglandins pmid:635221
Powell WS and Solomon S Biosynthesis of prostaglandins and thromboxane B2 by fetal lung homogenates. 1978 Prostaglandins pmid:635224
Ouwendijk RJ et al. Comparison of the production of eicosanoids by human and rat peritoneal macrophages and rat Kupffer cells. 1988 Prostaglandins pmid:2836891
Homo-Delarche F et al. Thymic hormones and prostaglandins. II. Synergistic effect on mouse spontaneous rosette forming cells. 1990 Prostaglandins pmid:2339201
Arima T et al. Changes in urinary thromboxane level in man during cardiopulmonary bypass: effect of thromboxane on renal tubules. 1990 Prostaglandins pmid:2339202
Tagari P et al. Measurement of canine urinary thromboxanes by GC-MS and HPLC-RIA. 1994 Prostaglandins pmid:8041872
Araki H et al. Mechanism of protection against arachidonate induced sudden death by glucocorticoid. 1981 Prostaglandins pmid:7232764
Goldsmith JC and Needleman SW A comparative study of thromboxane and prostacyclin release from ex vivo and cultured bovine vascular endothelium. 1982 Prostaglandins pmid:6815717
Keith JC et al. Ridogrel improves maternal/fetal homeostasis in an ovine model of pregnancy-induced hypertension. 1994 Prostaglandins pmid:8016393
Lord A et al. Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro. 1985 Prostaglandins pmid:3923570
Gorman RR et al. Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate. 1983 Prostaglandins pmid:6316421
Rogers TS et al. Differential alteration of lipoxygenase and cyclooxygenase metabolism by rat peritoneal macrophages induced by endotoxin tolerance. 1986 Prostaglandins pmid:3088676
Harris DN et al. Inhibition of prostaglandin biosynthesis by SQ 28,852, a 7-oxabicyclo[2.2.1]heptane analog. 1986 Prostaglandins pmid:3088677
Ogle CK et al. The production of C3, PGE2 and TxB2 by splenic, alveolar, and peritoneal guinea pig macrophages. 1988 Prostaglandins pmid:3237993
Abdel-Halim MS et al. Identification of prostaglandin D2 as a major prostaglandin in homogenates of rat brain. 1977 Prostaglandins pmid:594367
Williams KI and Downing I Prostaglandin and thromboxane production by rat decidual microsomes. 1977 Prostaglandins pmid:594385
Ali M et al. Synthesis of thromboxane B2 and prostaglandins by bovine gastric mucosal microsomes. 1977 Prostaglandins pmid:594386
Stenson WF et al. Metabolism of exogenous arachidonic acid by murine macrophage-like tumor cell lines. 1981 Prostaglandins pmid:6803301
Kelly KL and Laychock SG Prostaglandin synthesis and metabolism in isolated pancreatic islets of the rat. 1981 Prostaglandins pmid:6803305
Schneidkraut MJ and Carlson RW Cecal ligation and puncture is associated with pulmonary injury in the rat: role of cyclooxygenase pathway products. 1993 Prostaglandins pmid:8493358
Chiabrando C et al. Quantitative determination of 6-keto-PGF1 alpha released by rat aorta: comparison of mass fragmentography and high resolution gas chromatography with electron capture detection. 1980 Prostaglandins pmid:6894036
Uotila P et al. Prostanoids and hemodynamics in man before and during cardiopulmonary bypass. 1984 Prostaglandins pmid:6335260
Elliott GR et al. Copper modulation of macrophage cyclooxygenase metabolite synthesis. 1987 Prostaglandins pmid:3124217
Sadowitz PD et al. The platelet cyclooxygenase metabolite 12-L-hydroxy-5, 8, 10-hepta-decatrienoic acid (HHT) may modulate primary hemostasis by stimulating prostacyclin production. 1987 Prostaglandins pmid:3124219
Bloch MH et al. Prostaglandin production by the pregnant and non-pregnant rabbit uterus. 1983 Prostaglandins pmid:6415760
Hubbard HL et al. Extraction of thromboxane B2 from urine using an immobilized antibody column for subsequent analysis by gas chromatography-mass spectrometry. 1987 Prostaglandins pmid:3588968
Stock JL and Coderre JA Calcitonin enhances production of prostaglandins by stimulated human monocytes. 1984 Prostaglandins pmid:6087420
Closa D et al. A bradykinin antagonist inhibited nitric oxide generation and thromboxane biosynthesis in acute pancreatitis. 1995 Prostaglandins pmid:7659783
Chen MF et al. Fish oil supplementation attenuates myointimal proliferation of the abdominal aorta after balloon injury in diet-induced hypercholesterolemic rabbits. 1995 Prostaglandins pmid:7659784
Lagarde M et al. Nicergoline, an anti-aggregating agent which inhibits release of arachidonic acid from human platelet phospholipids. 1980 Prostaglandins pmid:7384555
Maggi FM et al. Prostaglandin synthetase activity in vascular tissue of male and female rats. 1980 Prostaglandins pmid:6770422
Neulen J et al. Arachidonic acid metabolism and prostaglandin production by primate preimplantation blastocysts. 1991 Prostaglandins pmid:1775634
Myers SI et al. Burn injury decreased splanchnic PGI2 release is restored by treatment with lazaroid. 1993 Prostaglandins pmid:8337413
Wetzka B et al. Eicosanoid production by intrauterine tissues before and after labor in short-term tissue culture. 1993 Prostaglandins pmid:8337416
Spagnuolo C et al. PGF2 alpha, thromboxane B2 and HETE levels in gerbil brain cortex after ligation of common carotid arteries and decapitation. 1979 Prostaglandins pmid:230539
Takeda H et al. Time course study for airway inflammation and responsiveness by repeated provocation of aeroantigen in guinea pigs. 1997 Prostaglandins pmid:9491210
She HS et al. Metabolism of prostaglandin endoperoxide by microsomes from cat lung. 1981 Prostaglandins pmid:6894797
Redfern JS et al. Gastroduodenal ulceration following active immunization with prostaglandin E2 in dogs. Role of gastric acid secretion. 1987 Prostaglandins pmid:3481091
Siler-Khodr TM et al. The effect of dexamethasone on CRH and prostanoid production from human term placenta. 1997 Prostaglandins pmid:9373879
Moonen P et al. An improved method for separation of thromboxane B2 by reversed phase liquid chromatography. 1983 Prostaglandins pmid:6669711
Chong KP et al. Vasopressin stimulates thromboxane synthesis in isolated hamster hepatocytes: relation to hepatocyte calcium content. 1983 Prostaglandins pmid:6419286
Worthington RE and Nakeff A Aspirin inhibits rat megakaryocyte thromboxane synthesis. 1982 Prostaglandins pmid:6812167
Harada Y et al. Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy. 1996 Prostaglandins pmid:8900441
Nambu F et al. OKY-046 inhibits anaphylactic bronchoconstriction and reduces histamine level in bronchoalveolar lavage fluid in sensitized guinea pigs. 1990 Prostaglandins pmid:1695383
Slama H et al. Metabolism of arachidonic acid by caruncular and allantochorionic tissues in cows with retained fetal membranes (RFM). 1993 Prostaglandins pmid:8380936
Datar S et al. Testing the "redirection hypothesis" of prostaglandin metabolism in the kidney. 1987 Prostaglandins pmid:3296006
Chiabrando C et al. Urinary excretion and origin of 11-dehydro-2,3-dinor-thromboxane B2 in man. 1993 Prostaglandins pmid:8321910
Shaw JO Effects of extracellular Ca2+ and the intracellular Ca2+ antagonist 8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate on rabbit platelet conversion of arachidonic acid into thromboxane. 1981 Prostaglandins pmid:6789402
Ingerman-Wojenski C et al. Prostacyclin production in rabbit arteries in situ: inhibition by arachidonic acid-induced endothelial cell damage or by low-dose aspirin. 1981 Prostaglandins pmid:6789404
Gimenez T et al. Fetal-maternal secretion of prostaglandins in the cow. 1983 Prostaglandins pmid:6576447
Ritter JM et al. Low dose aspirin treatment in late pregnancy differentially inhibits cyclo-oxygenase in maternal platelets. 1987 Prostaglandins pmid:3124218
Farker K et al. Measurements of urinary prostaglandins in young ovulatory women during the menstrual cycle and in postmenopausal women. 1997 Prostaglandins pmid:9373880
Westlund P et al. Circulating and urinary thromboxane B2 metabolites in the rabbit: 11-dehydro-thromboxane B2 as parameter of thromboxane production. 1986 Prostaglandins pmid:3520685
Landgraf-Leurs MM et al. Aggregation and thromboxane formation by platelets and vascular prostacyclin production from BB rats. An animal model for type I diabetes. 1982 Prostaglandins pmid:6812171
Reed MK et al. The effect of hypoxia on rat splanchnic prostanoid output. 1989 Prostaglandins pmid:2602564