Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Helicobacter Infections D016481 21 associated lipids
Infertility D007246 3 associated lipids
Embolism, Fat D004620 4 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Heart Septal Defects D006343 2 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Intermittent Claudication D007383 6 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Hydatidiform Mole D006828 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
van Dijk AP et al. Transdermal nicotine inhibits interleukin 2 synthesis by mononuclear cells derived from healthy volunteers. 1998 Eur. J. Clin. Invest. pmid:9767362
Oosaki R et al. Correlation among urinary eosinophil protein X, leukotriene E4, and 11-dehydrothromboxane B2 in patients with spontaneous asthmatic attack. 1998 Clin. Exp. Allergy pmid:9761018
Gajdos M et al. Effective long-term inhibition of thromboxane production but not of serotonin release in patients with coronary heart disease by 30 mg/d acetylsalicylic acid dosage. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9758203
Simon LS et al. Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects. 1998 Arthritis Rheum. pmid:9751091
Gonchar MV et al. Lack of direct connection between arachidonic acid release and prostanoid synthesis upon differentiation of U937 cell. 1998 Biochem. Biophys. Res. Commun. pmid:9731221
Roberts LJ et al. Metabolism of thromboxane B2 in the monkey. 1978 J. Biol. Chem. pmid:97291
Jain SK et al. Relationship of blood thromboxane-B2 (TxB2) with lipid peroxides and effect of vitamin E and placebo supplementation on TxB2 and lipid peroxide levels in type 1 diabetic patients. 1998 Diabetes Care pmid:9727900
Takami M and Tsukada W In vitro effect of DP-1904, a novel anti-asthma agent, against antigen-induced constriction and TXB2 release from the isolated guinea-pig lung parenchymal tissue. 1998 Pharmacol. Res. pmid:9721602
Takami M and Tsukada W Correlative alteration of thromboxane A2 with antigen-induced bronchoconstriction and the role of platelets as a source of TXA2 synthesis in guinea pigs: effect of DP-1904, an inhibitor of thromboxane synthetase. 1998 Pharmacol. Res. pmid:9721601
Saareks V et al. Nicotine stereoisomers and cotinine stimulate prostaglandin E2 but inhibit thromboxane B2 and leukotriene E4 synthesis in whole blood. 1998 Eur. J. Pharmacol. pmid:9721044
Durando MM et al. Endotoxin activation of mitogen-activated protein kinase in THP-1 cells; diminished activation following endotoxin desensitization. 1998 J. Leukoc. Biol. pmid:9715266
Hsiao G et al. Antiplatelet action of 3',4'-diisovalerylkhellactone diester purified from Peucedanum japonicum Thunb. 1998 Biol. Pharm. Bull. pmid:9703250
Ingster LM and Feinleib M Salicylate intake and cardiovascular disease: Ingster and Feinleib respond to Hu and Willett. 1998 Am J Public Health pmid:9702172
Iida T et al. The effects of a thromboxane A2 synthesis inhibitor and a prostaglandin I2 analogue on experimental acute necrotizing pancreatitis in rats. 1998 Pancreas pmid:9700944
Fagugli RM et al. Reduction of renal functional reserve in kidney transplant recipients: a possible role of arachidonic acid metabolism alterations. 1998 Clin. Nephrol. pmid:9696430
Levy M et al. Cerebrospinal fluid prostaglandins after systemic dipyrone intake. 1998 Clin. Pharmacol. Ther. pmid:9695726
Murphy NP et al. Functional relevance of the expression of ligand-induced binding sites in the response to platelet GP IIb/IIIa antagonists in vivo. 1998 J. Pharmacol. Exp. Ther. pmid:9694954
Ali M et al. Urothelial synthesis of prostanoids in the ovine ureter. 1998 Urol. Res. pmid:9694598
Lebel B et al. Inhibition of mediator release from dispersed nasal polyp cells by cyclosporin A. 1998 Int. Arch. Allergy Immunol. pmid:9693278
Napoli E and Franco N [Thromboxane A2 production in the pathogenesis of diabetic complications]. 1998 Minerva Endocrinol. pmid:9691631
Bell JG et al. Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9690713
Stephenson AH et al. 5,6-Epoxyeicosatrienoic acid reduces increases in pulmonary vascular resistance in the dog. 1998 Am. J. Physiol. pmid:9688901
Tewes KS et al. Measurement of thromboxane B2 in platelet-rich human plasma by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry following extractive pentafluorobenzyl esterification. 1998 Anal. Biochem. pmid:9683522
De La Cruz JP et al. Effect of camonagrel, a selective thromboxane synthase inhibitor, on retinal vascularization in experimental diabetes. 1998 Eur. J. Pharmacol. pmid:9683018
Onizuka M et al. Suppression of prostanoid formation and regulation of peripheral circulation after surgery using thrombin inhibitor (MD805). 1998 Surg. Today pmid:9681611
Cheng Z et al. Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. 1998 Inflammation pmid:9675607
Miyamoto A et al. The role of thromboxane A2 in regulating porcine basilar arterial tone. 1998 J. Vet. Pharmacol. Ther. pmid:9673964
Sheu JR et al. Inhibitory mechanisms of naloxone on human platelets. 1998 Jul-Aug Clin. Exp. Pharmacol. Physiol. pmid:9673433
Kunitoh H et al. A double-blind, placebo-controlled trial of the thromboxane synthetase blocker OKY-046 on bronchial hypersensitivity in bronchial asthma patients. 1998 J Asthma pmid:9669829
Geertsen PF et al. Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2. 1998 Clin. Sci. pmid:9662488
Adler S and Bollu R Glomerular endothelial cell injury mediated by shiga-like toxin-1. 1998 Kidney Blood Press. Res. pmid:9661132
Bode-Böger SM et al. Chronic dietary supplementation with L-arginine inhibits platelet aggregation and thromboxane A2 synthesis in hypercholesterolaemic rabbits in vivo. 1998 Cardiovasc. Res. pmid:9659460
Aoki T et al. Difference of (Ca2+)i movements in platelets stimulated by thrombin and TRAP: the involvement of alpha(IIb)beta3-mediated TXA2 synthesis. 1998 Thromb. Haemost. pmid:9657446
Schuligoi R et al. Effects of the cyclooxygenase-2 inhibitor NS-398 on thromboxane and leukotriene synthesis in rat peritoneal cells. 1998 Inflamm. Res. pmid:9657255
Bordia A et al. Effect of garlic (Allium sativum) on blood lipids, blood sugar, fibrinogen and fibrinolytic activity in patients with coronary artery disease. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9654398
Harada Y et al. Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat. 1998 Prostaglandins Other Lipid Mediat. pmid:9653772
Nagao T et al. Effect of lipo-prostaglandin E1 on crescentic-type anti-glomerular basement membrane nephritis in rats. 1998 Eur. J. Pharmacol. pmid:9650829
Assaley J et al. Effects of magnesium sulfate infusion upon clotting parameters in patients with pre-eclampsia. 1998 J Perinat Med pmid:9650132
Mainwaring RD et al. Complement activation and cytokine generation after modified Fontan procedure. 1998 Ann. Thorac. Surg. pmid:9647087
Whiteford M et al. Effect of liposome-encapsulated hemoglobin on the development of endotoxin-induced shock in the rat. 1998 Shock pmid:9645495
RogovyÄ­ IuE [Beta 2-microglobulin as a criterion of dysfunction in the regulation of proximal tubular activity in mercuric chloride-induced nephropathy]. 1998 May-Jun Urol Nefrol (Mosk) pmid:9644989
Li S and Tian H [Oral low-dose magnesium gluconate preventing pregnancy induced hypertension]. 1997 Zhonghua Fu Chan Ke Za Zhi pmid:9642379
Bereczki C et al. Increased platelet thromboxane release in focal segmental glomerulosclerosis. 1998 Nephrol. Dial. Transplant. pmid:9641208
Tu Y et al. Effect of intra-arachnoid space perfusion on thromboxane A and prostacycline in experimental spinal cord injury. 1997 J. Tongji Med. Univ. pmid:9639784
Lees P et al. Pharmacodynamics and pharmacokinetics of tolfenamic acid in ruminating calves: evaluation in models of acute inflammation. 1998 Vet. J. pmid:9638074
Cadroy Y et al. Arachidonic acid enhances the tissue factor expression of mononuclear cells by the cyclo-oxygenase-1 pathway: beneficial effect of n-3 fatty acids. 1998 J. Immunol. pmid:9637532
Franconi F et al. Further insights into the anti-aggregating activity of NMDA in human platelets. 1998 Br. J. Pharmacol. pmid:9630340
Ozyazgan I et al. Eicosanoids and inflammatory cells in frostbitten tissue: prostacyclin, thromboxane, polymorphonuclear leukocytes, and mast cells. 1998 Plast. Reconstr. Surg. pmid:9623831
Gust R et al. Synergistic hemodynamic effects of low-dose endotoxin and acute lung injury. 1998 Am. J. Respir. Crit. Care Med. pmid:9620928
Bassiouny HS et al. Low flow enhances platelet activation after acute experimental arterial injury. 1998 J. Vasc. Surg. pmid:9620144