Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Arthritis D001168 41 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Fatty Liver D005234 48 associated lipids
Thrombosis D013927 49 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Clark KE et al. Effect of bisenoic prostaglandins and arachidonic acid on the uterine vasculature of pregnant sheep. 1982 Am. J. Obstet. Gynecol. pmid:7065014
Schuette AH et al. Effect of lung thromboxane generation on regional blood flow during sheep bypass. 1982 Am. J. Physiol. pmid:7065206
Mäkilä UM et al. Regulation of prostacyclin and thromboxane production by human umbilical vessels: the effect of estradiol and progesterone in a superfusion model. 1982 Prostaglandins Leukot Med pmid:7043492
Han P et al. Inhibition of platelet function of antiarrhythmic drugs, verapamil and disopyramide. 1982 Thromb. Haemost. pmid:7101234
Krausz MM et al. Adverse effects of prostacyclin used to perfuse isolated lung lobes. 1982 Am. J. Physiol. pmid:7044149
Hirsh PD et al. Influence of blood sampling site and technique on thromboxane concentrations in patients with ischemic heart disease. 1982 Am. Heart J. pmid:7102506
Siess W et al. Plasma catecholamines, platelet aggregation and associated thromboxane formation after physical exercise, smoking or norepinephrine infusion. 1982 Circulation pmid:7044612
Chierchia S et al. Failure of thromboxane A2 blockade to prevent attacks of vasospastic angina. 1982 Circulation pmid:7116586
Sasagawa S et al. Effects of thromboxane A2 injection on the rabbit coronary artery. I. Physiologic effects in healthy animals. 1982 Exp. Mol. Pathol. pmid:7117494
Socini A et al. Effects of the coumarin derivative AD6 on platelet aggregation, platelet vessel wall interactions and 6 keto PGF1 alpha production in perfused aortas, in experimentally hypercholesterolaemic rabbits. 1982 Pharmacol Res Commun pmid:7048340
Fantone JC et al. Inhibition of vascular permeability changes in rats by captopril. 1982 J. Clin. Invest. pmid:6282931
Ylikorkala O and Viinikka L Effect of amnioscopy on concentrations of prostaglandin F2 alpha, prostacyclin and thromboxane in maternal plasma. 1982 Gynecol. Obstet. Invest. pmid:6954125
Simpson RM et al. Generation of thromboxane A2 and aorta-contracting activity from platelets stimulated with modified C-reactive protein. 1982 Immunology pmid:7118160
Leach CM and Thorburn GD A comparative study of collagen induced thromboxane release from platelets of different species: implications for human atherosclerosis models. 1982 Prostaglandins pmid:7122912
Bottoms GD et al. Thromboxane, prostaglandin I2 (epoprostenol), and the hemodynamic changes in equine endotoxin shock. 1982 Am. J. Vet. Res. pmid:7049018
Poubelle P et al. [Mononucleated phagocytes from rheumatoid synovial fluid. Synthesis of prostanoids and first pharmacological applications]. 1982 Rev Rhum Mal Osteoartic pmid:7123126
Homma T and Malik KU Effect of prostaglandins on pancreatic circulation in anesthetized dogs. 1982 J. Pharmacol. Exp. Ther. pmid:7050343
Bradlow BA and Chetty N Dosage frequency for suppression of platelet function by low dose aspirin therapy. 1982 Thromb. Res. pmid:7123514
Buchanan MR et al. Aspirin inhibits platelet function independent of the acetylation of cyclo-oxygenase. 1982 Thromb. Res. pmid:7071811
Tremoli E et al. Metformin reduces platelet hypersensitivity in hypercholesterolemic rabbits. 1982 Atherosclerosis pmid:7073794
Dorsch W et al. Mediator studies in skin blister fluid from patients with dual skin reactions after intradermal allergen injection. 1982 J. Allergy Clin. Immunol. pmid:6181112
Fletcher MS et al. Endotoxin, prostaglandins and renal fibrin deposition in obstructive jaundice. 1982 Br J Surg pmid:6751458
Shaw JO and Lyons RM Requirement for different Ca2+ pools in the activation of rabbit platelets II. Phospholipase activity. 1982 Biochim. Biophys. Acta pmid:6800410
Dejana E et al. Bleeding time in rats: a comparison of different experimental conditions. 1982 Thromb. Haemost. pmid:6753230
Axelrod L and Levine L Plasma prostaglandin levels in rats with diabetes mellitus and diabetic ketoacidosis. 1982 Diabetes pmid:6816644
DiMinno G et al. Stored human platelets retain full aggregation potential in response to pairs of aggregating agents. 1982 Blood pmid:6800418
Strano A et al. Platelet sensitivity to prostacyclin and thromboxane production in hyperlipidemic patients. 1982 Thromb. Haemost. pmid:6753232
Flynn JT and Demling RH Inhibition of endogenous thromboxane synthesis by exogenous prostacyclin during endotoxemia in conscious sheep. 1982 Adv Shock Res pmid:6753534
Grundfest CC et al. Acrolein: a potent modulator of lung macrophage arachidonic acid metabolism. 1982 Biochim. Biophys. Acta pmid:6814492
Smith MC et al. Prostacyclin substitution for heparin in long-term hemodialysis. 1982 Am. J. Med. pmid:6753575
Zipser RD and Martin K Urinary excretion of arterial blood prostaglandins and thromboxanes in man. 1982 Am. J. Physiol. pmid:6950668
Ylikorkala O et al. Prostacyclin and thromboxane in chronic uremia: effect of hemodialysis. 1982 Clin. Nephrol. pmid:6754193
Ylikorkala O et al. Production of prostacyclin and thromboxane during cesarean section. 1982 Obstet Gynecol pmid:6755324
Utsunomiya T et al. Modification of inflammatory response to aspiration with ibuprofen. 1982 Am. J. Physiol. pmid:6756172
Hamasaki Y et al. Hypoxia stimulates prostacyclin generation by dog lung in vitro. 1982 Prostaglandins Leukot Med pmid:7051045
Panganamala RV and Cornwell DG The effects of vitamin E on arachidonic acid metabolism. 1982 Ann. N. Y. Acad. Sci. pmid:6816121
Mitrovic D et al. The in vitro production of prostanoids by cultured bovine articular chondrocytes. 1982 Prostaglandins pmid:6801735
Watanabe T et al. Characterization of the biosynthetic pathway of prostaglandin D2 in human platelet-rich plasma. 1982 J. Biol. Chem. pmid:6816798
Foegh ML et al. Aspirin inhibition of thromboxane release in thrombosis and renal transplant rejection. 1982 Lancet pmid:6119441
Graham RM et al. Effects of short-term beta blockade on blood pressure, plasma thromboxane B2, and plasma and urinary prostaglandins E2 and F2 alpha in normal subjects. 1982 Clin. Pharmacol. Ther. pmid:6120775
Reines HD et al. Plasma thromboxane concentrations are raised in patients dying with septic shock. 1982 Lancet pmid:6123885
White JG and Rao GH Effects of a microtubule stabilizing agent on the response of platelets to vincristine. 1982 Blood pmid:6124288
Chong BH et al. Heparin-induced thrombocytopenia: association of thrombotic complications with heparin-dependent IgG antibody that induces thromboxane synthesis in platelet aggregation. 1982 Lancet pmid:6128550
De Caterina R et al. [Effects of isosorbide dinitrate on platelet aggregation and production of thromboxane B2]. 1982 Cardiologia pmid:6892461
Di Minno G et al. Arachidonic acid induces human platelet-fibrin retraction: the role of platelet cyclic endoperoxides. 1982 Thromb. Res. pmid:6803385
Suehiro A et al. The role of platelet hyperfunction in thrombus formation in hyperlipidemia. 1982 Thromb. Res. pmid:6803387
Needleman SW et al. Enrichment of human platelet phospholipids with linoleic acid diminishes thromboxane release. 1982 Prostaglandins pmid:6819602
Goldyne ME and Stobo JD Human monocytes synthesize eicosanoids from T lymphocyte-derived arachidonic acid. 1982 Prostaglandins pmid:6819603
Mehta P et al. Comparison of umbilical vein models for measurement of relative prostacyclin and thromboxane production. 1982 Prostaglandins pmid:6820165
Stuart MJ and Allen JB Arachidonic acid metabolism in the neonatal platelet. 1982 Pediatrics pmid:6804924
Nolan RD et al. The pericardium as a source of prostacyclin in the dog, ox and rat. 1982 Prostaglandins pmid:6820168
Wilson L et al. Alterations in reproductive tissue prostaglandins E and F, 6-keto-prostaglandin F1 alpha and thromboxane B2 with gestational age in the rat. 1982 Biol. Reprod. pmid:6897617
Randall MJ and Wilding RI Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with thromboxane synthetase inhibitor dazoxiben hydrochloride, (UK-37, 248-01). 1982 Thromb. Res. pmid:6897751
De Caterina R et al. [Effect of isosorbide dinitrate on platelet aggregation and production of thromboxane B2]. 1982 Cardiologia pmid:6927441
Davì G et al. [Effects of flurbiprofen on platelet function in patients with ischemic cardiomyopathy]. 1982 Cardiologia pmid:6927457
Whinnery MA et al. Thromboxane B2 and prostaglandin E2 in the rat kidney with unilateral ureteral obstruction. 1982 Am. J. Physiol. pmid:6950670
McNamara DB et al. Prostaglandin endoperoxide metabolism by microsomes of whole kidneys from normal, congenital unilateral hydronephrotic and unilateral ureteral obstructed rats. 1982 Prostaglandins pmid:6962465
Hornych A et al. [Urinary thromboxane B2 in hypertensive patients]. 1982 Arch Mal Coeur Vaiss pmid:6810812
Worthington RE and Nakeff A Aspirin inhibits rat megakaryocyte thromboxane synthesis. 1982 Prostaglandins pmid:6812167
Havill AM et al. alpha-Naphthylthiourea produces dose-dependent lung vascular injury in sheep. 1982 Am. J. Physiol. pmid:6812437
Lecompte T et al. Interference of transmethylation inhibitors with thromboxane synthesis in rat platelets. 1982 Biochem. Biophys. Res. Commun. pmid:6809005
Patrignani P et al. Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects. 1982 J. Clin. Invest. pmid:7045161
Bakhle YS and Zakrzewski JT Effects of the oestrous cycle on the metabolism of arachidonic acid in rat isolated lung. 1982 J. Physiol. (Lond.) pmid:6809935
Neri Serheri GG et al. Platelet aggregation and thromboxane A2 production after adrenergic stimulation in young healthy humans. 1982 Haemostasis pmid:6279476
Watkins WD et al. Thromboxane and pulmonary hypertension following E. coli endotoxin infusion in sheep: effect of an imidazole derivative. 1982 Prostaglandins pmid:7048422
Dore-Duffy P Differential effect of prostaglandins and other products of arachidonic acid metabolism on measles virus replication in Vero cells. 1982 Prostaglandins Leukot Med pmid:6281810
Miller OV et al. Acetyl glycerylphosphorylcholine inhibition of prostaglandin I2-stimulated adenosine 3',5'-cyclic monophosphate levels in human platelets. Evidence for thromboxane A2 dependence. 1982 Biochim. Biophys. Acta pmid:6285985
Hüttemeier PC et al. Acute pulmonary hypertension and lung thromboxane release after endotoxin infusion in normal and leukopenic sheep. 1982 Circ. Res. pmid:7042108
Kunkel SL et al. Production of cyclooxygenase products and superoxide anion by macrophages in response to chemotactic factors. 1982 Prostaglandins pmid:6300969
Rettkowski W et al. Studies of the influence of nitroglycerin on the synthesis of prostaglandins and thromboxane A2 and on platelet aggregation. 1982 Arzneimittelforschung pmid:6805480
Panossian A et al. On the mechanism of biosynthesis of leukotrienes and related compounds. 1982 FEBS Lett. pmid:6297982
Michelassi F et al. Leukotriene D4: a potent coronary artery vasoconstrictor associated with impaired ventricular contraction. 1982 Science pmid:6808665
Pawlowski NA et al. Uptake and metabolism of monohydroxy-eicosatetraenoic acids by macrophages. 1982 J. Exp. Med. pmid:6951919
Nugent WC et al. Prostaglandin response to intravenous nitroglycerin. 1982 J. Surg. Res. pmid:6810023
Scherhag R et al. Dietary administration of eicosapentaenoic and linolenic acid increases arterial blood pressure and suppresses vascular prostacyclin synthesis in the rat. 1982 Prostaglandins pmid:6285420
Watkins WD et al. Thromboxane and prostacyclin changes during cardiopulmonary bypass with and without pulsatile flow. 1982 J. Thorac. Cardiovasc. Surg. pmid:6980332
Malemud CJ et al. Correlation of the biosynthesis of prostaglandin and cyclic AMP in monolayer cultures of rabbit articular chondrocytes. 1982 Biochim. Biophys. Acta pmid:6280776
Kelton JG et al. Sex related differences in platelet function: the effect of aspirin. 1982 Blood pmid:7059670
Ylikorkala O et al. The effect of oral contraceptives on antiaggregatory prostacyclin and proaggregatory thromboxane A2 in humans. 1982 Am. J. Obstet. Gynecol. pmid:7036746
Kelton JG et al. Sex-related differences in the efficacy of acetylsalicylic acid (ASA) : the absorption of ASA and its effect on collagen-induced thromboxane B2 generation. 1981 Oct 1-15 Thromb. Res. pmid:7330835
Randall MJ et al. UK-37, 248, a novel, selective thromboxane synthetase inhibitor with platelet anti-aggregatory and anti-thrombotic activity. 1981 Jul 1-15 Thromb. Res. pmid:6795753
Tsuboi T et al. Effect of gliclazide on prostaglandin and thromboxane synthesis in guinea-pig platelets. 1981 Jan 1-15 Thromb. Res. pmid:7233394
Bockman RS Prostaglandin production by human blood monocytes and mouse peritoneal macrophages: synthesis dependent on in vitro culture conditions. 1981 Prostaglandins pmid:6782622
Singh D et al. Evidence for the generation of hydroxyl radical during arachidonic acid metabolism by human platelets. 1981 Am. J. Hematol. pmid:6274189
Smith EF and Lefer AM Stabilization of cardiac lysosomal and cellular membranes in protection of ischemic myocardium due to coronary occlusion:efficacy of the nonsteroidal anti-inflammatory agent, naproxen. 1981 Am. Heart J. pmid:7211667
Shaw JO et al. Activation of rabbit platelet phospholipase and thromboxane synthesis by 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (platelet activating factor). 1981 Biochim. Biophys. Acta pmid:7213765
Kass MA et al. Prostaglandin and thromboxane synthesis by microsomes of inflamed rabbit ciliary body--iris. 1981 Invest. Ophthalmol. Vis. Sci. pmid:7216665
Sakio H et al. [Release of thromboxane A2 during hemorrhagic shock (author's transl)]. 1981 Masui pmid:7218508
Townsend ER et al. Preservation of platelets during extracorporeal circulation in sheep. A comparison between aspirin and sulfinpyrazone. 1981 Circ. Res. pmid:7249281
McCann DS et al. Radioimmunoassay for plasma thromboxane B2. 1981 Clin. Chem. pmid:7273401
Feuerstein N et al. Leukotrienes C4 and D4 induce prostaglandin and thromboxane release from rat peritoneal macrophages. 1981 Br. J. Pharmacol. pmid:6894882
Karmazyn M et al. Comparative effects of acetylsalicylic acid (ASA) and sulfinpyrazone on isoproterenol-induced heart damage. 1981 J. Pharmacol. Exp. Ther. pmid:6894943
Morrison AR and Benabe JE Prostaglandins in vascular tone in experimental obstructive nephropathy. 1981 Kidney Int. pmid:6894950
Bombardieri S et al. The synovial prostaglandin system in chronic inflammatory arthritis: differential effects of steroidal and nonsteroidal anti-inflammatory drugs. 1981 Br. J. Pharmacol. pmid:6895043
Harms BA et al. Prostaglandin release and altered microvascular integrity after burn injury. 1981 J. Surg. Res. pmid:6895238
Defreyn G et al. Familial bleeding tendency with partial platelet thromboxane synthetase deficiency: reorientation of cyclic endoperoxide metabolism. 1981 Br. J. Haematol. pmid:6268139
Agradi E et al. In vitro effects of synthetic antioxidants and vitamin E on arachidonic acid metabolism and thromboxane formation in human platelets and on platelet aggregation. 1981 Prostaglandins pmid:6794104
Halushka PV et al. Increased platelet thromboxane synthesis in diabetes mellitus. 1981 J. Lab. Clin. Med. pmid:7452084
Laviolette M et al. Human alveolar macrophages: a lesion in arachidonic acid metabolism in cigarette smokers. 1981 Am. Rev. Respir. Dis. pmid:6794395
Landgraf-Leurs MM et al. Aggregation and thromboxane B2 formation in platelets and vascular prostacyclin production from genetically obese rats. 1981 Prostaglandins pmid:6798637