Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Death, Sudden, Cardiac D016757 12 associated lipids
Carotid Stenosis D016893 15 associated lipids
beta-Thalassemia D017086 5 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Osteoblastoma D018215 1 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Sepsis D018805 11 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
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Authors Title Published Journal PubMed Link
Pradalier A et al. [Measurement of plasma and serum values of PGE2, PGF2 alpha and TXB2 during aspirin induced bronchospasm in asthmatics (author's transl)]. 1979 Jul-Aug Therapie pmid:531778
Hagen AA et al. Synthesis of prostaglandins and thromboxane B2 by cerebral arteries. 1979 May-Jun Stroke pmid:462519
Spagnuolo PJ et al. Thromboxane A2 mediates augmented polymorphonuclear leukocyte adhesiveness. 1980 J. Clin. Invest. pmid:6772674
Best LC et al. The interrelationship between thromboxane biosynthesis, aggregation and 5-hydroxytryptamine secretion in human platelets in vitro. 1980 Thromb. Haemost. pmid:6773171
Olund A et al. Prostaglandins and thromboxanes in amniotic fluid during rivanol-induced abortion and labour. 1980 Prostaglandins pmid:6775353
Bisordi JE et al. Interaction of vasopressin and prostaglandins in the toad urinary bladder. 1980 J. Clin. Invest. pmid:6777397
Stuart MJ et al. The influence of albumin and calcium on human platelet arachidonic acid metabolism. 1980 Blood pmid:6766753
Challis JR and Patrick JE The production of prostaglandins and thromboxanes in the feto-placental unit and their effects on the developing fetus. 1980 Semin. Perinatol. pmid:6992278
Ahnfelt-Rønne I et al. Macrophages from adjuvent arthritic rats preferentially synthetize prostacyclin. 1980 Agents Actions pmid:6992544
Gullner HG et al. Correction of increased prostacyclin synthesis in Bartter's syndrome by indomethacin treatment. 1980 Prostaglandins Med pmid:6994153
Sanger GJ and Bennett A Trimethoquinol selectively antagonizes contractions of rat gastric fundus to TXB2 and epoxymethano analogs of PGH2. 1980 Adv Prostaglandin Thromboxane Res pmid:6103666
Zahavi J et al. Enhanced in-vivo platelet release reaction, increased thromboxane synthesis, and decreased prostacyclin release after tourniquet ischaemia. 1980 Lancet pmid:6106784
Galli C et al. Effects of 8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxy carboxyl methoxy coumarin (AD6) on aggregation, arachidonic acid metabolism and thromboxane B2 formation in human platelets. 1980 Pharmacol Res Commun pmid:7393988
Oka M and Manku MS Spironolactone decreases the formation of prostaglandins and related substances from arachidonic acid in rat vascular rings and human platelets. 1980 Prostaglandins Med pmid:7394062
Karmali RA et al. Intrarenal growth of the Walker 256 tumour and renal vein concentrations of PGE2, PGF 2 alpha, and TXB2: effects of diazepam. 1980 Prostaglandins Med pmid:7394064
Lindgren JA et al. Effects of platelet aggregation and adenosine 3':5'-monophosphate on the synthesis of thromboxane B2 in human platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:6247886
Cook JA et al. Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency. 1980 J. Clin. Invest. pmid:7350199
Stuart MJ et al. Effect of cholesterol on production of thromboxane b2 by platelets in vitro. 1980 N. Engl. J. Med. pmid:7350406
Maclouf J et al. Interactions of prostaglandin H2 and thromboxane A2 with human serum albumin. 1980 Eur. J. Biochem. pmid:7408901
Wise WC et al. Ibuprofen improves survival from endotoxic shock in the rat. 1980 J. Pharmacol. Exp. Ther. pmid:7452480