| MeSH term | MeSH ID | Detail |
|---|---|---|
| Death, Sudden, Cardiac | D016757 | 12 associated lipids |
| Carotid Stenosis | D016893 | 15 associated lipids |
| beta-Thalassemia | D017086 | 5 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Aortic Aneurysm, Abdominal | D017544 | 5 associated lipids |
| Osteoblastoma | D018215 | 1 associated lipids |
| Ventricular Dysfunction, Left | D018487 | 33 associated lipids |
| Systemic Inflammatory Response Syndrome | D018746 | 4 associated lipids |
| Sepsis | D018805 | 11 associated lipids |
| Atrial Premature Complexes | D018880 | 1 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Young JM et al. | Human whole blood assays for inhibition of prostaglandin G/H synthases-1 and -2 using A23187 and lipopolysaccharide stimulation of thromboxane B2 production. | 1996 | Inflamm. Res. | pmid:8737748 |
| Laffi G et al. | Defective aggregation in cirrhosis is independent of in vivo platelet activation. | 1996 | J. Hepatol. | pmid:8738730 |
| Yang JM et al. | Sodium nonivamide acetate: a non-pungently antinociceptive capsaicin derivative with unusual anti-inflammatory properties. | 1996 | Gen. Pharmacol. | pmid:8742512 |
| Yoshida T et al. | Abnormal prostanoid metabolism in lupus nephritis and the effects of a thromboxane A2 synthetase inhibitor, DP-1904. | 1996 | Lupus | pmid:8743126 |
| Mathie RT et al. | The haemodynamic effects of the thromboxane A2 receptor antagonist GR32191B during cardiopulmonary bypass in the dog. | 1995 | Perfusion | pmid:8747897 |
| Yokoyama I et al. | Liberation of vasoactive substances and its prevention with thromboxane A2 synthase inhibitor in pig liver transplantation. | 1996 | Transpl. Int. | pmid:8748415 |
| Gu YJ et al. | Leukocyte depletion results in improved lung function and reduced inflammatory response after cardiac surgery. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8751518 |
| Mito Y | [Thromboxane B2 (TXB2)]. | 1995 | Nippon Rinsho | pmid:8753342 |
| Janabi N et al. | Endogenous nitric oxide activates prostaglandin F2 alpha production in human microglial cells but not in astrocytes: a study of interactions between eicosanoids, nitric oxide, and superoxide anion (O2-) regulatory pathways. | 1996 | J. Immunol. | pmid:8757337 |
| Hibi S et al. | Structure-activity relationships of (E)-3-(1,4-benzoquinonyl)-2-[(3-pyridyl)-alkyl]-2-propenoic acid derivatives that inhibit both 5-lipoxygenase and thromboxane A2 synthetase. | 1996 | J. Med. Chem. | pmid:8759636 |
| Fimognari FL et al. | Associated daily biosynthesis of cortisol and thromboxane A2: a preliminary report. | 1996 | J. Lab. Clin. Med. | pmid:8759943 |
| Yan GT et al. | [Tumor necrosis factor induced enhancement of neutrophil chemotaxis and adhesion through mediating of phospholipase A2 activation]. | 1995 | Sheng Li Xue Bao | pmid:8762444 |
| Zhang M et al. | [Reduction of incidence of ischemia-reperfusion induced ventricular fibrillation by captopril]. | 1995 | Sheng Li Xue Bao | pmid:8762446 |
| Xiao J et al. | [Effects of platelet activating factor and platelet activating factor receptor antagonist on spinal cord blood flow after spinal cord injury]. | 1995 | Zhonghua Wai Ke Za Zhi | pmid:8762548 |
| Kuroiwa M et al. | Effects of granulocyte colony-stimulating factor on the hemostatic system in healthy volunteers. | 1996 | Int. J. Hematol. | pmid:8762814 |
| Fuse I et al. | Vascular thromboxane formation in hemostasis mechanism: correlation between bleeding time and vascular TXB2 in a patient with congenital platelet cyclo-oxygenase deficiency. | 1996 | Int. J. Hematol. | pmid:8762815 |
| Izaki S et al. | Platelet-activating factor and arachidonic acid metabolites in psoriatic inflammation. | 1996 | Br. J. Dermatol. | pmid:8763425 |
| Fleisch JH et al. | Recombinant human secretory phospholipase A2 released thromboxane from guinea pig bronchoalveolar lavage cells: in vitro and ex vivo evaluation of a novel secretory phospholipase A2 inhibitor. | 1996 | J. Pharmacol. Exp. Ther. | pmid:8764358 |
| Hrboticky N et al. | Linoleic acid esterified in low density lipoprotein serves as substrate for increased arachidonic acid synthesis in differentiating monocytic cells. | 1996 | Biochim. Biophys. Acta | pmid:8765140 |
| Qiu BS et al. | Protection by recombinant human interleukin-11 against experimental TNB-induced colitis in rats. | 1996 | Dig. Dis. Sci. | pmid:8769290 |
| Shirabe K et al. | Inhibition of thromboxane A2 activity during warm ischemia of the liver. | 1996 | J. Surg. Res. | pmid:8769950 |
| Abernathy VJ et al. | C-reactive protein inhibits increased pulmonary vascular permeability induced by fMLP in isolated rabbit lungs. | 1996 | Am. J. Physiol. | pmid:8770090 |
| Closa D et al. | Hepatic involvement in pancreatitis-induced lung damage. | 1996 | Am. J. Physiol. | pmid:8772495 |
| Mehta PJ et al. | More uses of known drugs. | 1995 | J Assoc Physicians India | pmid:8773057 |
| Madan ZM and Sainani GS | Effect of aspirin treatment on plasma levels of keto PGF 1 alpha and thromboxane B2. | 1995 | J Assoc Physicians India | pmid:8773058 |
| Quoc KP and Pascaud M | Effects of dietary gamma-linolenic acid on the tissue phospholipid fatty acid composition and the synthesis of eicosanoids in rats. | 1996 | Ann. Nutr. Metab. | pmid:8773734 |
| Nabe T et al. | Sephadex G-200-induced eosinophil infiltration into airways in non-sensitized and sensitized guinea pigs, and responsiveness of the cells to stimuli in vitro. | 1996 | Jpn. J. Pharmacol. | pmid:8774762 |
| Gennaro M et al. | Perfluorocarbon emulsion prevents eicoasanoid release in skeletal muscle ischemia and reperfusion. | 1996 | Cardiovasc Surg | pmid:8782946 |
| Uhlig S et al. | Cyclooxygenase-2-dependent bronchoconstriction in perfused rat lungs exposed to endotoxin. | 1996 | Mol. Med. | pmid:8784790 |
| Cuzzolin L et al. | Effect of single and repeated doses of a new nitroderivative of acetylsalicylic acid on platelet TXA2 production in rats. | 1996 | Life Sci. | pmid:8786689 |
| Zheng NX et al. | Pharmacokinetic and pharmacodynamic studies of a thromboxane synthetase inhibitor, ozagrel, in rabbits. | 1995 | Biol. Pharm. Bull. | pmid:8787798 |
| Bell SJ et al. | Dietary fish oil and cytokine and eicosanoid production during human immunodeficiency virus infection. | 1996 Jan-Feb | JPEN J Parenter Enteral Nutr | pmid:8788262 |
| Raptopoulos D et al. | The effect of xylazine on plasma thromboxane B2 concentration in sheep. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8789696 |
| Vaskonen T et al. | Interrelationships between salt and fish oil in stroke-prone spontaneously hypertensive rat. | 1996 | Blood Press. | pmid:8790929 |
| Aïssa J et al. | Biochemical and cellular effects of heparin-protamine injection in rabbits are partially inhibited by a PAF-acether receptor antagonist. | 1996 | Eur. J. Pharmacol. | pmid:8791000 |
| Collins CE et al. | Picotamide inhibition of excess in vitro thromboxane B2 release by colorectal mucosa in inflammatory bowel disease. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791957 |
| Eriksson M et al. | Beneficial effects of pre-treatment with vitamin A on cardiac and pulmonary functions in endotoxaemic pigs. | 1996 | Acta Anaesthesiol Scand | pmid:8792882 |
| Uematsu T et al. | Pharmacokinetic and pharmacodynamic properties of FK070 (KDI-792), a novel thromboxane receptor antagonist/thromboxane synthetase inhibitor, after single and multiple oral administrations to healthy volunteers. | 1996 | J. Pharm. Pharmacol. | pmid:8794987 |
| Ko FN et al. | Mechanism of action of p-chlorobiphenyl on the inhibition of platelet aggregation. | 1996 | J. Pharm. Pharmacol. | pmid:8794990 |
| Sakurai S et al. | Synthesis of [[(benzenesulfonamido)alkyl]phenyl]alkanoic acid derivatives containing pyridyl or imidazolyl groups and their thromboxane A2 receptor antagonistic and thromboxane A2 synthase inhibitory activities. | 1996 | Chem. Pharm. Bull. | pmid:8795270 |
| Fox GA et al. | Cyclooxygenase inhibition and vascular reactivity in a rat model of hyperdynamic sepsis. | 1996 | J. Cardiovasc. Pharmacol. | pmid:8797133 |
| Morrow JD et al. | Nonenzymatic free radical-catalyzed generation of thromboxane-like compounds (isothromboxanes) in vivo. | 1996 | J. Biol. Chem. | pmid:8798513 |
| Lewy RI et al. | Intravenous heparin initiates in-vivo synthesis and release of thromboxane in angina pectoris. | 1979 | Lancet | pmid:87990 |
| Fekkes D et al. | Eicosanoid and amino acid metabolism in transient acute psychoses with psychedelic symptoms. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8804122 |
| Feng J et al. | Beneficial effects of iloprost cardioplegia in ischemic arrest in isolated working rat heart. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8804125 |
| González ET et al. | Prostanoid modulation of glucose transport in isolated diabetic rat uterus. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8804128 |
| Giulian D et al. | Activated microglia are the principal glial source of thromboxane in the central nervous system. | 1996 | Neurochem. Int. | pmid:8808790 |
| Zhen ZY et al. | Experimental study on microthrombi and myocardial injuries. | 1996 | Microvasc. Res. | pmid:8812763 |
| Pace-Asciak CR et al. | Wines and grape juices as modulators of platelet aggregation in healthy human subjects. | 1996 | Clin. Chim. Acta | pmid:8814965 |
| Yoshida SH et al. | Dietary Juniperis virginiensis seed oil decreased pentobarbital-associated mortalities among DBA/1 mice treated with collagen-adjuvant emulsions. | 1996 | J Lipid Mediat Cell Signal | pmid:8816989 |
| Landoni MF et al. | Pharmacokinetics and pharmacodynamics of tolfenamic acid in calves. | 1996 | Res. Vet. Sci. | pmid:8819190 |
| Galbraith EA and McKellar QA | Protein binding and in vitro serum thromboxane B2 inhibition by flunixin meglumine and meclofenamic acid in dog, goat and horse blood. | 1996 | Res. Vet. Sci. | pmid:8819199 |
| Davì G et al. | Influence of metabolic control on thromboxane biosynthesis and plasma plasminogen activator inhibitor type-1 in non-insulin-dependent diabetes mellitus. | 1996 | Thromb. Haemost. | pmid:8819248 |
| Wagner RS et al. | Activation of thromboxane A2 receptors alters lipopolysaccharide-induced adherence of THP-1 cells. | 1996 | Shock | pmid:8821102 |
| Meenan J et al. | Lexipafant (BB-882), a platelet activating factor receptor antagonist, ameliorates mucosal inflammation in an animal model of colitis. | 1996 | Eur J Gastroenterol Hepatol | pmid:8823572 |
| Watanabe M et al. | [Changes in platelet sensitivity to thromboxane A2 in pediatric patients with nephrotic syndrome]. | 1996 | Nihon Jinzo Gakkai Shi | pmid:8828355 |
| Mitten LA et al. | Phenylbutazone increases right atrial pressure and heart rate of running horses. | 1996 | J. Appl. Physiol. | pmid:8828679 |
| Ishibashi M et al. | Identification of 11-dehydro-2,3-dinorthromboxane B3 in human urine based on the mass spectral properties of 11-dehydrothromboxane B3 and related compounds. | 1995 | Rapid Commun. Mass Spectrom. | pmid:8829476 |
| Mizugaki M et al. | Microdetermination of 11-dehydrothromboxane B3 in human urine by gas chromatography--selected-ion monitoring using (18O2) analogue as an internal standard. | 1995 | Rapid Commun. Mass Spectrom. | pmid:8829485 |
| Myers SI et al. | Long-term resuscitation of hemorrhage/reperfusion injury (H/R) stimulates renal PGE2 release. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8832762 |
| Osiovich H et al. | Cardiopulmonary effects of tumor necrosis factor-alpha in the piglet: influence of cyclooxygenase inhibition. | 1995 | Biol. Neonate | pmid:8835089 |
| Meade CJ et al. | Pulmonary pharmacology of DT-TX 30 SE, a potent selective combined thromboxane synthetase inhibitor and receptor antagonist, in guinea pigs. | 1996 | Jpn. J. Pharmacol. | pmid:8835638 |
| Fylling AC et al. | Kinetic and structural evidence for the identification of 11-hydroxythromboxane B2 dehydrogenase as cytosolic aldehyde dehydrogenase. | 1995 Nov-Dec | Prostaglandins | pmid:8838239 |
| Muller M and Sorrell TC | Inhibition of the human platelet cyclooxygenase response by the naturally occurring phenazine derivative, 1-hydroxyphenazine. | 1995 Nov-Dec | Prostaglandins | pmid:8838240 |
| Stichtenoth DO et al. | Increased total body synthesis of prostacyclin in rats with adjuvant arthritis. | 1995 Nov-Dec | Prostaglandins | pmid:8838242 |
| Nowak J et al. | Thromboxane metabolite excretion in patients with hand-arm vibration syndrome. | 1996 | Clin Physiol | pmid:8842572 |
| Cuiper LL et al. | Systemic and pulmonary hypertension after abrupt cessation of prostacyclin: role of thromboxane A2. | 1996 | J. Appl. Physiol. | pmid:8847301 |
| Horiguchi T et al. | Pulmonary responses to heparin-protamine complexes: the effects of age and species. | 1996 | J. Appl. Physiol. | pmid:8847332 |
| Gabriel A et al. | Influence of prostaglandin E1 on tissue ischemia during surgical repair of the abdominal aorta. | 1996 | J. Cardiothorac. Vasc. Anesth. | pmid:8850397 |
| Chen SJ et al. | Antiplatelet and calcium inhibitory properties of eugenol and sodium eugenol acetate. | 1996 | Gen. Pharmacol. | pmid:8853295 |
| Quinn JV et al. | Evaluation of enzyme-linked immunosorbent assays for quantitation of eicosanoid mediators of sepsis syndrome. | 1996 | Shock | pmid:8856849 |
| Reale M et al. | Human recombinant interleukin-1 beta induces thromboxane A2 release in polymorphonuclear leukocytes, macrophages and platelets: effect of IL-1 receptor antagonist. | 1996 | Mol. Cell. Biochem. | pmid:8858567 |
| Bordia T et al. | An evaluation of garlic and onion as antithrombotic agents. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8860105 |
| Pancera P et al. | Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8860111 |
| Kanai H et al. | Serotonin metabolism in patients undergoing hemodialysis. | 1996 | Clin. Nephrol. | pmid:8861800 |
| Siler-Khodr TM et al. | Dose-related action of estradiol on placental prostanoid prediction. | 1996 | Prostaglandins | pmid:8873234 |
| Schaefer WR et al. | Urinary excretion of 2,3-dinor-6-keto-PGF1 alpha and 11-dehydro-TXB2 by the gravid spontaneously hypertensive rat. | 1996 | Prostaglandins | pmid:8875634 |
| Mustad V et al. | Seasonal variation in parameters related to coronary heart disease risk in young men. | 1996 | Atherosclerosis | pmid:8879440 |
| Selley ML et al. | The effect of cholesterol oxidation products on human platelet aggregation. | 1996 | Thromb. Res. | pmid:8885139 |
| Ziyyat A et al. | Interactions between nitric oxide and prostanoids in isolated perfused kidneys of the rat. | 1996 | Br. J. Pharmacol. | pmid:8886425 |
| GarcÃa-Lafuente A et al. | Bacterial peptides enhance inflammatory activity in a rat model of colitis. | 1996 | Digestion | pmid:8886582 |
| Carbajal D et al. | Possible cytoprotective mechanism in rats of D-002, an anti-ulcerogenic product isolated from beeswax. | 1996 | J. Pharm. Pharmacol. | pmid:8887738 |
| Stiris TA et al. | Effects of dexamethasone on retinal and choroidal blood flow during normoxia and hyperoxia in newborn piglets. | 1996 | Pediatr. Res. | pmid:8888288 |
| Myers SI et al. | Estrogen increases male rat aortic endothelial cell (RAEC) PGI2 release. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8888351 |
| Chou TC et al. | The inhibitory effect of 2-thienyl 2'-hydroxyphenyl ketone (C85) on platelet thromboxane formation. | 1996 | Thromb. Res. | pmid:8897698 |
| Harada Y et al. | Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy. | 1996 | Prostaglandins | pmid:8900441 |
| Karck U et al. | PGE2 and PGF2 alpha release by human peritoneal macrophages in endometriosis. | 1996 | Prostaglandins | pmid:8900443 |
| Livingston ER et al. | Increased activation of the coagulation and fibrinolytic systems leads to hemorrhagic complications during left ventricular assist implantation. | 1996 | Circulation | pmid:8901751 |
| Serebruany VL et al. | Mac-1 inhibitor affects certain hemostatic parameters during myocardial stunning in swine. | 1996 | Pharmacology | pmid:8902873 |
| Parnas BL et al. | Isolation and structure of leukotriene-A4 hydrolase inhibitor: 8(S)-amino-2(R)-methyl-7-oxononanoic acid produced by Streptomyces diastaticus. | 1996 | J. Nat. Prod. | pmid:8904845 |
| Martin W et al. | Respiratory dysfunction and white cell activation following cardiopulmonary bypass: comparison of membrane and bubble oxygenators. | 1996 | Eur J Cardiothorac Surg | pmid:8905281 |
| Montuschi P et al. | Tachykinin NK2 receptor antagonists decrease eicosanoid release in lung anaphylaxis. | 1996 | Eur. J. Pharmacol. | pmid:8905345 |
| Nishisho T et al. | Experimental and clinical studies of eicosanoids in cerebrospinal fluid after spinal cord injury. | 1996 | Neurosurgery | pmid:8905750 |
| Berdeaux O et al. | Effects of a trans isomer of arachidonic acid on rat platelet aggregation and eicosanoid production. | 1996 | J. Lipid Res. | pmid:8906600 |
| Schmid P et al. | Passive smoking and platelet thromboxane. | 1996 | Thromb. Res. | pmid:8907294 |
| Chello M et al. | Reduction by indobufen of neutrophil activation in peripheral arterial occlusive disease. | 1996 | J. Cardiovasc. Pharmacol. | pmid:8907804 |
| Szekacs B et al. | Prostacyclin and thromboxane production of rat and cat arterial tissue is altered independently by several vasoactive substances. | 1996 | Prostaglandins | pmid:8908622 |
| Ferrándiz ML et al. | Effect of bakuchiol on leukocyte functions and some inflammatory responses in mice. | 1996 | J. Pharm. Pharmacol. | pmid:8910867 |
| Okada M et al. | Two mechanisms for platelet-mediated killing of tumour cells: one cyclo-oxygenase dependent and the other nitric oxide dependent. | 1996 | Immunology | pmid:8911154 |
| Shibasaki T et al. | Mizoribine reduces urinary protein excretion in rats given puromycin aminonucleoside. | 1996 | Am. J. Nephrol. | pmid:8919236 |