| MeSH term | MeSH ID | Detail |
|---|---|---|
| Death, Sudden, Cardiac | D016757 | 12 associated lipids |
| Carotid Stenosis | D016893 | 15 associated lipids |
| beta-Thalassemia | D017086 | 5 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Aortic Aneurysm, Abdominal | D017544 | 5 associated lipids |
| Osteoblastoma | D018215 | 1 associated lipids |
| Ventricular Dysfunction, Left | D018487 | 33 associated lipids |
| Systemic Inflammatory Response Syndrome | D018746 | 4 associated lipids |
| Sepsis | D018805 | 11 associated lipids |
| Atrial Premature Complexes | D018880 | 1 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yoshino T et al. | Pharmacological profile of celecoxib, a specific cyclooxygenase-2 inhibitor. | 2005 | Arzneimittelforschung | pmid:16080279 |
| Mancini F et al. | Time since menopause does not affect plasma viscosity, plasma thromboxane levels and Doppler findings. | 2005 | Gynecol. Endocrinol. | pmid:16019357 |
| Mancini F et al. | Effects of hormone replacement therapy on plasma viscosity and Doppler variations in postmenopausal non-smokers and heavy smokers. | 2005 | Gynecol. Endocrinol. | pmid:16019365 |
| Michibayashi T | Platelet aggregation and vasoconstriction related to platelet cyclooxygenase and 12-lipoxygenase pathways. | 2005 | J. Atheroscler. Thromb. | pmid:16020916 |
| Svenstrup Poulsen T et al. | A critical appraisal of the phenomenon of aspirin resistance. | 2005 | Cardiology | pmid:16020925 |
| Walsh DS et al. | Characterization of circulating monocytes expressing HLA-DR or CD71 and related soluble factors for 2 weeks after severe, non-thermal injury. | 2005 | J. Surg. Res. | pmid:16045935 |
| Rodrigue ME et al. | Cyclooxygenase inhibition with acetylsalicylic acid unmasks a role for prostacyclin in erythropoietin-induced hypertension in uremic rats. | 2005 | Can. J. Physiol. Pharmacol. | pmid:16049546 |
| Montuschi P et al. | Effects of cyclo-oxygenase inhibition on exhaled eicosanoids in patients with COPD. | 2005 | Thorax | pmid:16192367 |
| Hsiao G et al. | alpha-Naphthoflavone, a potent antiplatelet flavonoid, is mediated through inhibition of phospholipase C activity and stimulation of cyclic GMP formation. | 2005 | J. Agric. Food Chem. | pmid:15969494 |
| Munsterhjelm E et al. | Characterization of inhibition of platelet function by paracetamol and its interaction with diclofenac in vitro. | 2005 | Acta Anaesthesiol Scand | pmid:15954969 |
| Vangroenweghe F et al. | Effect of carprofen treatment following experimentally induced Escherichia coli mastitis in primiparous cows. | 2005 | J. Dairy Sci. | pmid:15956299 |
| Wakamoto S et al. | Effects of hemoglobin vesicles on resting and agonist-stimulated human platelets in vitro. | 2005 | Artif Cells Blood Substit Immobil Biotechnol | pmid:15960075 |
| Al Kadi H et al. | A prospective, longitudinal study of the renin-angiotensin system, prostacyclin and thromboxane in the first trimester of normal human pregnancy: association with birthweight. | 2005 | Hum. Reprod. | pmid:16006463 |
| Beretta C et al. | COX-1 and COX-2 inhibition in horse blood by phenylbutazone, flunixin, carprofen and meloxicam: an in vitro analysis. | 2005 | Pharmacol. Res. | pmid:15939622 |
| Visioli F et al. | Virgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients. | 2005 | Eur J Nutr | pmid:15309433 |
| Jin YR et al. | Antiplatelet activity of J78 (2-Chloro-3-[2'-bromo, 4'-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), an antithrombotic agent, is mediated by thromboxane (TX) A2 receptor blockade with TXA2 synthase inhibition and suppression of cytosolic Ca2+ mobilization. | 2005 | J. Pharmacol. Exp. Ther. | pmid:15328379 |
| Jin YR et al. | An antithrombotic agent, NQ301, inhibits thromboxane A2 receptor and synthase activity in rabbit platelets. | 2005 | Basic Clin. Pharmacol. Toxicol. | pmid:16128910 |
| Jermany J et al. | Lumiracoxib does not affect the ex vivo antiplatelet aggregation activity of low-dose aspirin in healthy subjects. | 2005 | J Clin Pharmacol | pmid:16172182 |
| Persico N et al. | Transdermal HRT and Doppler findings in normotensive and hypertensive postmenopausal patients. | 2005 | Ultrasound Obstet Gynecol | pmid:16184506 |
| Perini JA et al. | Influence of CYP2C9 genotypes on the pharmacokinetics and pharmacodynamics of piroxicam. | 2005 | Clin. Pharmacol. Ther. | pmid:16198655 |
| Davì G et al. | Helicobacter pylori infection causes persistent platelet activation in vivo through enhanced lipid peroxidation. | 2005 | Arterioscler. Thromb. Vasc. Biol. | pmid:15472127 |
| Maree AO et al. | Platelet response to low-dose enteric-coated aspirin in patients with stable cardiovascular disease. | 2005 | J. Am. Coll. Cardiol. | pmid:16198840 |
| Saloheimo P et al. | Thromboxane and prostacyclin biosynthesis in patients with acute spontaneous intracerebral hemorrhage. | 2005 | Thromb. Res. | pmid:15733969 |
| Trebino CE et al. | Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. | 2005 | J. Biol. Chem. | pmid:15722356 |
| GarcÃa-Saura MF et al. | Effects of chronic quercetin treatment in experimental renovascular hypertension. | 2005 | Mol. Cell. Biochem. | pmid:15792364 |
| Awad AS et al. | Increased renal production of angiotensin II and thromboxane B2 in conscious diabetic rats. | 2005 | Am. J. Hypertens. | pmid:15831366 |
| De Candia E et al. | Abnormal pH-sensing of platelet Na+/H+ exchanger in patients with cardiac syndrome X. | 2005 | Int. J. Cardiol. | pmid:15837078 |
| Capone ML et al. | Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects. | 2005 | J. Am. Coll. Cardiol. | pmid:15837265 |
| Oliveira RL et al. | Postmenopausal hormone replacement therapy increases plasmatic thromboxane beta 2. | 2005 | Int. J. Cardiol. | pmid:15771927 |
| Cryer B et al. | Double-blind, randomized, parallel, placebo-controlled study of ibuprofen effects on thromboxane B2 concentrations in aspirin-treated healthy adult volunteers. | 2005 | Clin Ther | pmid:15811481 |
| Chang Y et al. | Mechanisms involved in the antiplatelet activity of ketamine in human platelets. | 2004 Nov-Dec | J. Biomed. Sci. | pmid:15591773 |
| Barrière G et al. | PHGPx overexpression induces an increase in COX-2 activity in colon carcinoma cells. | 2004 May-Jun | Anticancer Res. | pmid:15274299 |
| Böhm E et al. | 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. | 2004 | J. Biol. Chem. | pmid:14668348 |
| Persico N et al. | Transdermal hormone replacement therapy and Doppler findings in normal and overweight postmenopausal patients. | 2004 | Gynecol. Endocrinol. | pmid:15726916 |
| He J et al. | Treatment of unstable angina pectoris with modified nuan gan jian--a report of 33 cases. | 2004 | J Tradit Chin Med | pmid:15688691 |
| Arruzazabala ML et al. | Effects of d-003, a new substance purified from sugar cane wax, on platelet aggregation and plasma levels of arachidonic acid metabolites in healthy volunteers. | 2004 | Int J Clin Pharmacol Res | pmid:15689052 |
| Kudolo GB et al. | The ingestion of Ginkgo biloba extract (EGb 761) inhibits arachidonic acid-mediated platelet aggregation and thromboxane B2 production in healthy volunteers. | 2004 | J Herb Pharmacother | pmid:15927922 |
| Lam AN et al. | Effect of red clover isoflavones on cox-2 activity in murine and human monocyte/macrophage cells. | 2004 | Nutr Cancer | pmid:15456640 |
| Moriguchi A et al. | Antithrombotic effects of FK419, a novel nonpeptide platelet GPIIb/IIIa antagonist, in a guinea pig photochemically induced middle cerebral artery thrombosis model: comparison with ozagrel and argatroban. | 2004 | J. Pharmacol. Exp. Ther. | pmid:14634048 |
| Xu L et al. | [Effects of effective component from "qing kai ling" on endothelial cell of microvessel in MCAO rats]. | 2004 | Zhong Yao Cai | pmid:15376390 |
| Perneby C et al. | Prothrombotic responses to exercise are little influenced by clopidogrel treatment. | 2004 | Thromb. Res. | pmid:15381386 |
| Hennekens CH et al. | Terms and conditions: semantic complexity and aspirin resistance. | 2004 | Circulation | pmid:15381661 |
| Zhao GR et al. | [Clinical study on relationship between sluggishness of lung-defensive qi and levels of vasoactive intestinal polypeptide and thromboxane B2]. | 2004 | Zhong Xi Yi Jie He Xue Bao | pmid:15383251 |
| Fiorucci S et al. | Co-administration of nitric oxide-aspirin (NCX-4016) and aspirin prevents platelet and monocyte activation and protects against gastric damage induced by aspirin in humans. | 2004 | J. Am. Coll. Cardiol. | pmid:15358033 |
| Ming HX et al. | [Influence of single leaf Asarum himalaicum on renal function of rabbits]. | 2004 | Zhong Xi Yi Jie He Xue Bao | pmid:15339444 |
| Dey A et al. | Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. | 2004 | Obes. Res. | pmid:15340111 |
| Sheu JR et al. | Expression of matrix metalloproteinase-9 in human platelets: regulation of platelet activation in in vitro and in vivo studies. | 2004 | Br. J. Pharmacol. | pmid:15289295 |
| Toth B et al. | Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. | 2004 | J. Appl. Physiol. | pmid:15298985 |
| Valeri CR et al. | In vitro effects of poly-N-acetyl glucosamine on the activation of platelets in platelet-rich plasma with and without red blood cells. | 2004 | J Trauma | pmid:15280746 |
| Singer P and Wirth M | Can n-3 PUFA reduce cardiac arrhythmias? Results of a clinical trial. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15253884 |
| Barbieri SS et al. | Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms. | 2004 | Free Radic. Biol. Med. | pmid:15203187 |
| Kojima F et al. | Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis. | 2004 | Arthritis Res. Ther. | pmid:15225371 |
| Farndale RW et al. | Measurement of platelet arachidonic acid metabolism. | 2004 | Methods Mol. Biol. | pmid:15226540 |
| Barbara J et al. | Inhaled cornstarch glove powder increases latex-induced airway hyper-sensitivity in guinea-pigs. | 2004 | Clin. Exp. Allergy | pmid:15196289 |
| Wu KJ et al. | [Detection of thromboxane B2, 6-keto-prostaglandin F1alpha and anticardiolipin antibody in patients with obstructive sleep apnea-hypopnea syndrome]. | 2004 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:15196341 |
| Van Ryn J et al. | Meloxicam does not affect the antiplatelet effect of aspirin in healthy male and female volunteers. | 2004 | J Clin Pharmacol | pmid:15199082 |
| Aikawa K et al. | Effects of antioxidants on coronary microvascular spasm induced by epicardial coronary artery endothelial injury in pigs. | 2004 | Coron. Artery Dis. | pmid:15201617 |
| Lorenzoni R et al. | Short-term prevention of thromboembolic complications in patients with atrial fibrillation with aspirin plus clopidogrel: the Clopidogrel-Aspirin Atrial Fibrillation (CLAAF) pilot study. | 2004 | Am. Heart J. | pmid:15215815 |
| Korkushko OV et al. | [Some mechanisms of the development of endothelial disfunction in aging]. | 2004 | Fiziol Zh | pmid:15174205 |
| Kawano T et al. | Acetaldehyde induces histamine release from human airway mast cells to cause bronchoconstriction. | 2004 | Int. Arch. Allergy Immunol. | pmid:15178893 |
| Ishitsuka Y et al. | Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs. | 2004 | J. Pharm. Pharmacol. | pmid:15099446 |
| Dinev D and Andonova M | The effect of general anesthesia and abdominal surgery upon plasma thromboxane B concentrations in horses. | 2004 | Vet Anaesth Analg | pmid:15053753 |
| Menzies-Gow NJ et al. | Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators. | 2004 | Equine Vet. J. | pmid:15147137 |
| Ghuysen A et al. | Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism. | 2004 | J. Pharmacol. Exp. Ther. | pmid:15121765 |
| Caprani A et al. | Experimental evidence of a potentially increased thrombo-embolic disease risk by domestic electromagnetic field exposure. | 2004 | Bioelectromagnetics | pmid:15114641 |
| Di Minno G and Violi F | Aspirin resistance and diabetic angiopathy: back to the future. | 2004 | Thromb. Res. | pmid:15115664 |
| Torsney E et al. | Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection. | 2004 | Circ. Res. | pmid:15117816 |
| Wang YY et al. | Inhibition of platelet aggregation by polyaspartoyl L-arginine and its mechanism. | 2004 | Acta Pharmacol. Sin. | pmid:15066215 |
| Park HS et al. | Dietary conjugated linoleic acid increases the mRNA ratio of Bax/Bcl-2 in the colonic mucosa of rats. | 2004 | J. Nutr. Biochem. | pmid:15068816 |
| Zhang C et al. | Inhibition of inflammation contributes to organ protection of atenolol in sinoaortic-denervated rats. | 2004 | J. Cardiovasc. Pharmacol. | pmid:15071353 |
| Bruno A et al. | Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction. | 2004 | Stroke | pmid:14963281 |
| Kwak SH et al. | Effects of propofol on endotoxin-induced acute lung injury in rabbit. | 2004 | J. Korean Med. Sci. | pmid:14966342 |
| de La Puerta Vázquez R et al. | Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils. | 2004 | Metab. Clin. Exp. | pmid:14681843 |
| von Aulock S et al. | Granulocyte colony-stimulating factor (filgrastim) treatment primes for increased ex vivo inducible prostanoid release. | 2004 | J. Pharmacol. Exp. Ther. | pmid:14610236 |
| Minuz P et al. | Determinants of platelet activation in human essential hypertension. | 2004 | Hypertension | pmid:14656953 |
| Liu P et al. | [Effects of the extracts from decoction for resuscitation and its component herbs on PGI2, TXA2 and NO release from rat vascular endothelial cells under hypoxia in vitro]. | 2004 | Zhongguo Zhong Yao Za Zhi | pmid:15631091 |
| Yang JP et al. | [Changes of the platelet function and serum anticardiolipin antibody in patients with pulmonary thromboembolism]. | 2004 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:15634381 |
| Wang MS et al. | [The effects of lupus anticoagulant on pulmonary thromboembolism]. | 2004 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:15634384 |
| Franz KB | A functional biological marker is needed for diagnosing magnesium deficiency. | 2004 | J Am Coll Nutr | pmid:15637224 |
| Cardoni RL and Antúnez MI | Circulating levels of cyclooxygenase metabolites in experimental Trypanosoma cruzi infections. | 2004 | Mediators Inflamm. | pmid:15545053 |
| Wu JX et al. | Changes in somatostatin receptor expression of the pancreas and effectiveness of octreotide in rats with acute necrotizing pancreatitis. | 2004 | Chin J Dig Dis | pmid:15612670 |
| Berrougui H et al. | Argan (Argania spinosa) oil lowers blood pressure and improves endothelial dysfunction in spontaneously hypertensive rats. | 2004 | Br. J. Nutr. | pmid:15613254 |
| Fan JG et al. | [Dynamic changes of plasma levels of prostacycline and thromboxane A2 and their correlation with the severity of hepatic injury in rats with nonalcoholic fatty liver disease]. | 2004 | Zhonghua Gan Zang Bing Za Zhi | pmid:15623379 |
| DÃaz AM et al. | Phenylpropanoid glycosides from Scrophularia scorodonia: in vitro anti-inflammatory activity. | 2004 | Life Sci. | pmid:15010262 |
| Tsai CY et al. | Proinflammatory cytokines enhance COX-1 gene expression in cultured rat glomerular mesangial cells. | 2004 | Int. Immunopharmacol. | pmid:14975359 |
| Rotondo S et al. | Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation. | 2004 | Eur. J. Pharmacol. | pmid:15044038 |
| Guay J et al. | Carrageenan-induced paw edema in rat elicits a predominant prostaglandin E2 (PGE2) response in the central nervous system associated with the induction of microsomal PGE2 synthase-1. | 2004 | J. Biol. Chem. | pmid:15044444 |
| Véricel E et al. | Diabetic patients without vascular complications display enhanced basal platelet activation and decreased antioxidant status. | 2004 | Diabetes | pmid:15047620 |
| Yugar-Toledo JC et al. | Uncontrolled hypertension, uncompensated type II diabetes, and smoking have different patterns of vascular dysfunction. | 2004 | Chest | pmid:15006938 |
| Vega-Ostertag M et al. | Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin. | 2004 | Arthritis Rheum. | pmid:15457460 |
| Noverr MC and Huffnagle GB | Regulation of Candida albicans morphogenesis by fatty acid metabolites. | 2004 | Infect. Immun. | pmid:15501745 |
| Tanigawa T et al. | Anti-inflammatory effect of two isoforms of COX in H. pylori-induced gastritis in mice: possible involvement of PGE2. | 2004 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12958020 |
| Rocca B et al. | Modulation of the expression and activity of cyclooxygenases in normal and accelerated erythropoiesis. | 2004 | Exp. Hematol. | pmid:15504548 |
| Chou DS et al. | Low concentration of oxidized low density lipoprotein suppresses platelet reactivity in vitro: an intracellular study. | 2004 | Lipids | pmid:15506238 |
| He W et al. | Effects of the Chinese drugs for activating blood circulation on plasma TXB2 and 6-keto-PGF1alpha contents in rabbits with glucocorticoid-induced femoral head necrosis. | 2004 | J Tradit Chin Med | pmid:15510809 |
| Chiang N et al. | Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15471991 |
| Park WH et al. | Inhibitory effect of GBH on platelet aggregation through inhibition of intracellular Ca2+ mobilization in activated human platelets. | 2004 | Life Sci. | pmid:15474558 |
| Chen BN et al. | [Characteristic changes of vascular tension factors in diabetic arterial occlusion of lower extremities]. | 2004 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:15495823 |
| Horani MH et al. | Cyclooxygenase inhibition is associated with downregulation of apolipoprotein AI promoter activity in cultured hepatoma cell line HepG2. | 2004 | Metab. Clin. Exp. | pmid:14767868 |
| Peck OM et al. | Staphylococcus aureus and lipopolysaccharide induce homologous tolerance but heterologous priming: role of interferon-gamma. | 2004 | Shock | pmid:14770039 |