Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Biliary Tract Neoplasms D001661 7 associated lipids
Behcet Syndrome D001528 7 associated lipids
Bartter Syndrome D001477 5 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Asthma D001249 52 associated lipids
Asthenia D001247 5 associated lipids
Ascites D001201 25 associated lipids
Arthus Reaction D001183 8 associated lipids
Arthritis, Juvenile D001171 8 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Fujiwara T et al. Exploratory aspirin resistance trial in healthy Japanese volunteers (J-ART) using platelet aggregation as a measure of thrombogenicity. 2007 Pharmacogenomics J. pmid:17245331
Maree AO et al. Drug insight: aspirin resistance-fact or fashion? 2007 Nat Clin Pract Cardiovasc Med pmid:17330121
Rossoni G et al. Positive interaction of the novel beta2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs. 2007 Pulm Pharmacol Ther pmid:16533614
Jeng JH et al. Antiplatelet effect of sanguinarine is correlated to calcium mobilization, thromboxane and cAMP production. 2007 Atherosclerosis pmid:16797553
Gurbel PA et al. Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study. 2007 Circulation pmid:17562955
Tu CT et al. Antifibrotic activity of rofecoxib in vivo is associated with reduced portal hypertension in rats with carbon tetrachloride-induced liver injury. 2007 J. Gastroenterol. Hepatol. pmid:17565644
Zheng BH et al. [The effect of inhaled nitric oxide on endothelium-derived angiokinetic factors in patients with acute high altitude disease]. 2007 Zhonghua Jie He He Hu Xi Za Zhi pmid:17445476
Suzuki A et al. Ferulic acid restores endothelium-dependent vasodilation in aortas of spontaneously hypertensive rats. 2007 Am. J. Hypertens. pmid:17485012
Basselin M et al. Chronic lithium administration attenuates up-regulated brain arachidonic acid metabolism in a rat model of neuroinflammation. 2007 J. Neurochem. pmid:17488274
Gracia-Sancho J et al. Enhanced vasoconstrictor prostanoid production by sinusoidal endothelial cells increases portal perfusion pressure in cirrhotic rat livers. 2007 J. Hepatol. pmid:17459512
Yu XM et al. [Relations of platelet phospholipid fatty acids to thrombotic risk factors in middle-aged and geriatric patients with hyperlipidemia]. 2007 Zhonghua Yi Xue Za Zhi pmid:17418017
Sha JP et al. [Effect of the recombinant staphylokinase on pancreatic ischemia in severe acute pancreatitis of rats]. 2007 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:17708840
Silvanto M et al. Effect of 3 g of intravenous paracetamol on post-operative analgesia, platelet function and liver enzymes in patients undergoing tonsillectomy under local anaesthesia. 2007 Acta Anaesthesiol Scand pmid:17711562
Xing X and Li H Isolated liver perfusion for regional chemotherapy in rats. 2007 HBPD INT pmid:17690035
Shemesh E et al. Symptoms of posttraumatic stress disorder in patients who have had a myocardial infarction. 2006 May-Jun Psychosomatics pmid:16684940
Tuominen OM et al. Effects of bisphosphonates on prostaglandin E2 and thromboxane B2 production in human whole blood and monocytes stimulated by lipopolysaccharide and A23187. 2006 Jul-Aug Methods Find Exp Clin Pharmacol pmid:16894405
Wang LH et al. Effect of heparin on activation of platelet function in patients during radiofrequency catheter ablation. 2006 Jan-Feb Clin. Exp. Pharmacol. Physiol. pmid:16445701
Wynn RL and Cook J Does ibuprofen block the cardioprotective effects of aspirin in dental patients? 2006 Jan-Feb Gen Dent pmid:16494111
Kranzhofer R and Ruef J Aspirin resistance in coronary artery disease is correlated to elevated markers for oxidative stress but not to the expression of cyclooxygenase (COX) 1/2, a novel COX-1 polymorphism or the PlA(1/2) polymorphism. 2006 Platelets pmid:16702043
Chen GG et al. Increased thromboxane B(2) levels are associated with lipid peroxidation and Bcl-2 expression in human lung carcinoma. 2006 Cancer Lett. pmid:15876485
Zhou Y et al. Increased expression of cyclooxygenase-2 mediates enhanced contraction to endothelin ETA receptor stimulation in endothelial nitric oxide synthase knockout mice. 2006 Circ. Res. pmid:16645140
Wilder-Smith CH et al. Dose-effect comparisons of the CINOD AZD3582 and naproxen on upper gastrointestinal tract mucosal injury in healthy subjects. 2006 Scand. J. Gastroenterol. pmid:16497612
Brenneis C et al. Inhibition of prostaglandin E2 synthesis by SC-560 is independent of cyclooxygenase 1 inhibition. 2006 FASEB J. pmid:16816110
Chiu HF et al. Mechanisms involved in the antiplatelet effect of C-phycocyanin. 2006 Br. J. Nutr. pmid:16469164
Rossoni G et al. Nitric oxide and prostacyclin pathways: an integrated mechanism that limits myocardial infarction progression in anaesthetized rats. 2006 Pharmacol. Res. pmid:16488624
Lepäntalo A et al. Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients. 2006 Thromb. Haemost. pmid:16493486
Kurosawa S et al. Effects of ulinastatin on pulmonary artery pressure during abdominal aortic aneurysmectomy. 2006 J Clin Anesth pmid:16517327
Flipo RM [Are the NSAIDs able to compromising the cardio-preventive efficacy of aspirin?]. 2006 Presse Med pmid:17078596
Dołegowska B et al. Metabolism of eicosanoids and their action on renal function during ischaemia and reperfusion: the effect of alprostadil. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:17011760
Ong TZ et al. Nonsteroidal anti-inflammatory drug use is a significant cause of peptic ulcer disease in a tertiary hospital in Singapore: a prospective study. 2006 J. Clin. Gastroenterol. pmid:17016134
Morchón R et al. High levels of serum thromboxane B2 are generated during human pulmonary dirofilariosis. 2006 Clin. Vaccine Immunol. pmid:17028222
Cook-Johnson RJ et al. Endothelial cell COX-2 expression and activity in hypoxia. 2006 Biochim. Biophys. Acta pmid:17046322
Zhao Y et al. Effect of a Chinese herbal formula, Shi-Bi-Lin, on an experimental model of allergic rhinitis. 2006 Ann. Allergy Asthma Immunol. pmid:16802773
Lee KS et al. Antiplatelet activity of [5-(2-methoxy-5-chlorophenyl)furan-2-ylcarbonyl]guanidine (KR-32570), a novel sodium/hydrogen exchanger-1 and its mechanism of action. 2006 Arch. Pharm. Res. pmid:16756082
Peck OM et al. The phosphatidylinositol 3 kinase pathway regulates tolerance to lipopolysaccharide and priming responses to Staphylococcus aureus and lipopolysaccharide. 2006 Shock pmid:16783195
Frelinger AL et al. Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. 2006 Circulation pmid:16785341
Cox D et al. Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers. 2006 Stroke pmid:16794200
Munsterhjelm E et al. Influence on platelet aggregation of i.v. parecoxib and acetaminophen in healthy volunteers. 2006 Br J Anaesth pmid:16698862
Vranic II et al. Adenosine cardioprotection study in clinical setting of paroxysmal supraventricular tachycardia. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:16682179
Huntjens DR et al. Correlation between in vitro and in vivo concentration-effect relationships of naproxen in rats and healthy volunteers. 2006 Br. J. Pharmacol. pmid:16682968
Park HS et al. Dietary trans-10, cis-12 and cis-9,trans-11 conjugated linoleic acids induce apoptosis in the colonic mucosa of rats treated with 1,2-dimethylhydrazine. 2006 J Med Food pmid:16579724
Ohmori T et al. Aspirin resistance detected with aggregometry cannot be explained by cyclooxygenase activity: involvement of other signaling pathway(s) in cardiovascular events of aspirin-treated patients. 2006 J. Thromb. Haemost. pmid:16706971
Perneby C et al. Dose- and time-dependent antiplatelet effects of aspirin. 2006 Thromb. Haemost. pmid:16601836
Hrushka NH et al. [Effect of thromboxane B2 on morphological features of apoptosis in cultured rat hepatocytes exposed to hepatotropic substances]. 2006 Fiziol Zh pmid:17176837
Niemi TT et al. The effect of N-acetylcysteine on blood coagulation and platelet function in patients undergoing open repair of abdominal aortic aneurysm. 2006 Blood Coagul. Fibrinolysis pmid:16607076
Stergioulas AT and Filippou DK Effects of physical conditioning on lipids and arachidonic acid metabolites in untrained boys: a longitudinal study. 2006 Appl Physiol Nutr Metab pmid:16900233
Fujimoto Y et al. Monochloramine potently inhibits arachidonic acid metabolism in rat platelets. 2006 Biochem. Biophys. Res. Commun. pmid:16615995
Xu S et al. The thromboxane receptor antagonist S18886 attenuates renal oxidant stress and proteinuria in diabetic apolipoprotein E-deficient mice. 2006 Diabetes pmid:16380483
Chiang N et al. Aspirin has a gender-dependent impact on antiinflammatory 15-epi-lipoxin A4 formation: a randomized human trial. 2006 Arterioscler. Thromb. Vasc. Biol. pmid:16293793
Wolfram RM et al. Salivary isoprostanes indicate increased oxidation injury in periodontitis with additional tobacco abuse. 2006 Biofactors pmid:17264390