Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Bronchopulmonary Sequestration D001998 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Varicose Veins D014648 7 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Macular Edema D008269 3 associated lipids
Aortic Rupture D001019 3 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Diseases in Twins D004200 4 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
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Authors Title Published Journal PubMed Link
Ross S et al. Association of cyclooxygenase-2 genetic variant with cardiovascular disease. 2014 Eur. Heart J. pmid:24796340
Zhou K et al. A CAPE analogue as novel antiplatelet agent efficiently inhibits collagen-induced platelet aggregation. 2014 Pharmazie pmid:25158573
Maurer K et al. Acetylsalicylic acid enhances tachyphylaxis of repetitive capsaicin responses in TRPV1-GFP expressing HEK293 cells. 2014 Neurosci. Lett. pmid:24495935
Shimizu T et al. Up-regulation of Kv7.1 channels in thromboxane A2-induced colonic cancer cell proliferation. 2014 Pflugers Arch. pmid:23995773
Montserrat-de la Paz S et al. Long-chain fatty alcohols from evening primrose oil inhibit the inflammatory response in murine peritoneal macrophages. 2014 J Ethnopharmacol pmid:24239848
Mayer AM et al. Vibrio vulnificus MO6-24/O lipopolysaccharide stimulates superoxide anion, thromboxane Bâ‚‚, matrix metalloproteinase-9, cytokine and chemokine release by rat brain microglia in vitro. 2014 Mar Drugs pmid:24675728
van den Elsen LW et al. Dietary fish oil improves endothelial function and lowers blood pressure via suppression of sphingolipid-mediated contractions in spontaneously hypertensive rats. 2014 J. Hypertens. pmid:24569415
Hill TL et al. The effect of tramadol and indomethacin coadministration on gastric barrier function in dogs. 2014 May-Jun J. Vet. Intern. Med. pmid:24684670
Olszowski T et al. The Effect of Cadmium on COX-1 and COX-2 Gene, Protein Expression, and Enzymatic Activity in THP-1 Macrophages. 2015 Biol Trace Elem Res pmid:25645360
Al-Husseini A et al. Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension. 2015 PLoS ONE pmid:25785937
Mateu A et al. Cross-talk between TLR4 and PPARγ pathways in the arachidonic acid-induced inflammatory response in pancreatic acini. 2015 Int. J. Biochem. Cell Biol. pmid:26510582
Liu TF et al. [Correlation between the level of the urinary 11-dehydrothromboxane B2 and the clinical efficacy of aspirin in patients with type 2 diabetes and coronary artery disease]. 2015 Beijing Da Xue Xue Bao pmid:26679651
Holland B et al. Pharmacokinetics and pharmacodynamics of three formulations of firocoxib in healthy horses. 2015 J. Vet. Pharmacol. Ther. pmid:25378135
Violi F et al. Reply: platelets interplay between pneumonia and cardiovascular events: establishing a link? 2015 J. Am. Coll. Cardiol. pmid:25857919
Khan AR et al. Platelet activation and myocardial infarction in patients with pneumonia: are statins the answer? 2015 J. Am. Coll. Cardiol. pmid:25857918
Gavriilaki E et al. Platelets interplay between pneumonia and cardiovascular events: establishing a link? 2015 J. Am. Coll. Cardiol. pmid:25857917
Véricel E et al. Moderate oral supplementation with docosahexaenoic acid improves platelet function and oxidative stress in type 2 diabetic patients. 2015 Thromb. Haemost. pmid:25832443
Khanna V et al. Does the response to aspirin and clopidogrel vary over 6 months in patients with ischemic heart disease? 2015 J. Thromb. Haemost. pmid:25809653
Wu F et al. Valsartan decreases platelet activity and arterial thrombotic events in elderly patients with hypertension. 2015 Chin. Med. J. pmid:25591555
Paikin JS et al. Multiple daily doses of acetyl-salicylic acid (ASA) overcome reduced platelet response to once-daily ASA after coronary artery bypass graft surgery: a pilot randomized controlled trial. 2015 J. Thromb. Haemost. pmid:25546465