Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Bronchopulmonary Sequestration D001998 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Varicose Veins D014648 7 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Macular Edema D008269 3 associated lipids
Aortic Rupture D001019 3 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Diseases in Twins D004200 4 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Pärsson HN et al. Maintaining carotid flow by shunting during carotid endarterectomy diminishes the inflammatory response mediating ischaemic brain injury. 2000 Eur J Vasc Endovasc Surg pmid:10727360
Zaitsu M et al. Ulinastatin, an elastase inhibitor, inhibits the increased mRNA expression of prostaglandin H2 synthase-type 2 in Kawasaki disease. 2000 J. Infect. Dis. pmid:10720537
Okada S et al. Perfusion of the hypothalamic paraventricular nucleus with N-methyl-D-aspartate produces thromboxane A2 and centrally activates adrenomedullary outflow in rats. 2000 Neuroscience pmid:10717438
Weber AA et al. 40 mg of aspirin are not sufficient to inhibit platelet function under conditions of limited compliance. 2000 Thromb. Res. pmid:10709913
Suntres ZE and Shek PN Prophylaxis against lipopolysaccharide-induced lung injuries by liposome-entrapped dexamethasone in rats. 2000 Biochem. Pharmacol. pmid:10704946
Nosál R and Jancinová V Nonreceptor interactions in the pharmacology of blood platelets. 1999 Gen. Physiol. Biophys. pmid:10703730
Tegeder I et al. Effects of selective and unselective cyclooxygenase inhibitors on prostanoid release from various rat organs. 2000 J. Pharmacol. Exp. Ther. pmid:10688636
Nagano K et al. Prostanoids regulate proliferation of vascular smooth muscle cells induced by arginine vasopressin. 2000 Eur. J. Pharmacol. pmid:10686292
Zeng W et al. [Relationship between PGI2, TXA2 and threatened preterm]. 1998 Hua Xi Yi Ke Da Xue Xue Bao pmid:10684102
De La Cruz JP et al. Effect of DT-TX 30, a combined thromboxane synthase inhibitor and thromboxane receptor antagonist, on retinal vascularity in experimental diabetes mellitus. 2000 Thromb. Res. pmid:10680643
Wu TM et al. Inhibitory effect of hexapeptide (RGRHGD) on platelet aggregation. 2000 Thromb. Res. pmid:10674405
Okumura M et al. Renal production of thromboxane and prostaglandins in a rat model of type 2 diabetes. 2000 Life Sci. pmid:10670825
Leese PT et al. Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: a randomized, controlled trial. 2000 J Clin Pharmacol pmid:10664917
Matsumoto H and Nakao T Elevated urinary excretion of thromboxane B2 in adults with minimal-change nephrotic syndrome. 2000 Clin. Nephrol. pmid:10661487
Hansen JM et al. Effects of nitric oxide blockade and cyclosporin A on cardiovascular and renal function in normal man. 1999 J. Hypertens. pmid:10658936
Landoni MF et al. Enantiospecific pharmacokinetics and pharmacodynamics of ketoprofen in sheep. 1999 J. Vet. Pharmacol. Ther. pmid:10651463
Chou TC et al. Mechanism of inhibition of platelet aggregation by HCL-31D. 2000 Eur. J. Pharmacol. pmid:10650152
Montini G et al. Renal glomerular response to the inhibition of prostaglandin E2 synthesis and protein loading after the relief of unilateral ureteropelvic junction obstruction. 2000 J. Urol. pmid:10647684
Gajdos M et al. [The effect of monotherapy with ciprofibrate and in combination with acetylsalicylic acid on the spectrum of lipids, thromboxane and fibrinogen in patients with atherosclerosis and hyperlipoproteinemia]. 1999 Bratisl Lek Listy pmid:10645034
Stewart KG et al. Estrogen decreases prostaglandin H synthase products from endothelial cells. 1999 Nov-Dec J. Soc. Gynecol. Investig. pmid:10643586
González E et al. Evolution of streptozotocin-pancreatic damage in the rat: modulatory effect of endothelins on the nitridergic and prostanoid pathway. 1999 Nitric Oxide pmid:10637124
Miura M and Kurimoto F [Thromboxane B2 (TXB2)]. 1999 Nippon Rinsho pmid:10635957
Perneby C et al. Optimization of an enzyme immunoassay for 11-dehydro-thromboxane B(2) in urine: comparison with GC-MS. 1999 Thromb. Res. pmid:10632465
Dahlin KL et al. Amitriptyline-induced release of endothelin-1 in isolated perfused and ventilated rat lungs. 1999 Pharmacol. Toxicol. pmid:10628905
Tanus-Santos JE et al. The hemodynamic effects of endothelin receptor antagonism during a venous air infusion in dogs. 2000 Anesth. Analg. pmid:10624986
Uriu K et al. Effect of acute thromboxane A2 inhibition on the renal hemodynamics in a spontaneously non-insulin-dependent diabetic rat, Otsuka Long-Evans Tokushima Fatty rat. 1999 Jul-Aug J. Diabetes Complicat. pmid:10616856
Ferro D et al. Determinants of enhanced thromboxane biosynthesis in patients with systemic lupus erythematosus. 1999 Arthritis Rheum. pmid:10616019
Eldor A et al. A chronic hypercoagulable state in patients with beta-thalassaemia major is already present in childhood. 1999 Br. J. Haematol. pmid:10606878
Reis F et al. The peripheral serotonergic system and platelet aggregation in cyclosporin A-induced hypertensive rats. 1999 Thromb. Res. pmid:10605951
De La Cruz JP et al. Antiplatelet effect of the anaesthetic drug propofol: influence of red blood cells and leucocytes. 1999 Br. J. Pharmacol. pmid:10602334
Chou TC and Li CY Inhibitory mechanisms of dantrolene on platelet aggregation. 1999 Thromb. Res. pmid:10593433
Kohda N et al. Effect of cilostazol, a phosphodiesterase III inhibitor, on experimental thrombosis in the porcine carotid artery. 1999 Thromb. Res. pmid:10593428
Hoch B and Bernhard M Reduced prostacyclin to thromboxane A2 ratio is correlated with central apneas in preterm infants. 1999 Prostaglandins Other Lipid Mediat. pmid:10593170
Hishinuma T et al. Urinary thromboxane A2/prostacyclin balance reflects the pathological state of a diabetic. 1999 Prostaglandins Other Lipid Mediat. pmid:10593168
Mizugaki M et al. Monitoring of the thromboxane A2/prostacyclin ratio in the urine of patients with retinal vascular occlusion through the low-dose-aspirin therapy using the gas chromatography/selected ion monitoring method. 1999 Prostaglandins Other Lipid Mediat. pmid:10593167
Pavord ID et al. Induced sputum eicosanoid concentrations in asthma. 1999 Am. J. Respir. Crit. Care Med. pmid:10588604
Pirich C et al. Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. 1999 Thromb. Res. pmid:10588465
Gallery ED et al. In vitro human decidual endothelial cell thromboxane secretion in preeclampsia is not abnormal. 1999 Hypertens Pregnancy pmid:10586525
Vijaya Kumar M et al. The anhydrous milk fat, ghee, lowers serum prostaglandins and secretion of leukotrienes by rat peritoneal macrophages. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10574649
Castellani S et al. Impaired renal adaptation to stress in the elderly with isolated systolic hypertension. 1999 Hypertension pmid:10567190
Titos E et al. Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4). 1999 Am. J. Physiol. pmid:10564079
Heller A et al. Pancreatitis-associated protein protects the lung from leukocyte-induced injury. 1999 Anesthesiology pmid:10551593
Hirakata H et al. Propofol has both enhancing and suppressing effects on human platelet aggregation in vitro. 1999 Anesthesiology pmid:10551587
Nemcova S et al. Cyclic nucleotides and production of prostanoids in human varicose veins. 1999 J. Vasc. Surg. pmid:10550185
Reeves JH et al. Continuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group. 1999 Crit. Care Med. pmid:10548188
de Meijer A et al. Meloxicam, 15 mg/day, spares platelet function in healthy volunteers. 1999 Clin. Pharmacol. Ther. pmid:10546927
Pearl JM et al. Effect of modified ultrafiltration on plasma thromboxane B2, leukotriene B4, and endothelin-1 in infants undergoing cardiopulmonary bypass. 1999 Ann. Thorac. Surg. pmid:10543508
Chou TC et al. Antiplatelet effect of amlodipine: a possible mechanism through a nitric oxide-mediated process. 1999 Biochem. Pharmacol. pmid:10535758
Serebruany VL et al. Effects of a novel Mac-1 inhibitor, NPC 15669, on hemostatic parameters during preconditioned myocardial infarction. 1999 Life Sci. pmid:10530802
Véricel E et al. The influence of low intake of n-3 fatty acids on platelets in elderly people. 1999 Atherosclerosis pmid:10525140
Cryer B et al. Effects of cutaneous aspirin on the human stomach and duodenum. 1999 Sep-Oct Proc. Assoc. Am. Physicians pmid:10519166
Yang SY and Gao ZX Determination and clinical significance of plasma levels of prostaglandins in patients with acute brain injury. 1999 Surg Neurol pmid:10511080
Thakur V et al. Antihypertensive effect of the combination of fosinopril and HCTZ is resistant to interference by nonsteroidal antiinflammatory drugs. 1999 Am. J. Hypertens. pmid:10509552
Gust R et al. Role of cyclooxygenase-2 in oleic acid-induced acute lung injury. 1999 Am. J. Respir. Crit. Care Med. pmid:10508803
Gonchar M et al. Kinetics of prostanoid synthesis by macrophages is regulated by arachidonic acid sources. 1999 Eur. J. Biochem. pmid:10504410
Tanus-Santos JE et al. Inhaled nitric oxide improves hemodynamics during a venous air infusion (VAI) in dogs. 1999 Intensive Care Med pmid:10501756
Barchasz E et al. Interleukin-1beta-induced hyperresponsiveness to [Sar9,Met(O2)11]substance P in isolated human bronchi. 1999 Eur. J. Pharmacol. pmid:10499376
Fruzzetti F et al. Platelet-vessel wall interactions with third-generation oral contraceptives: no evidence of detrimental effects. 1999 Thromb. Haemost. pmid:10494782
Fuglsang J et al. Intravenous acetylsalicylic acid, magnesium and their combination in experimental arterial thrombosis in rats. 1999 Blood Coagul. Fibrinolysis pmid:10493216
Obata T et al. Simultaneous assay of prostaglandins and thromboxane in the cerebrospinal fluid by gas chromatography-mass spectrometry-selected ion monitoring. 1999 J. Chromatogr. B Biomed. Sci. Appl. pmid:10491991
Nishimaki S and Seki K An imbalance between prostacyclin and thromboxane in relation to cerebral blood flow in neonates with maternal preeclampsia. 1999 Prostaglandins Other Lipid Mediat. pmid:10482286
Nawarskas JJ et al. Effect of aspirin on blood pressure in hypertensive patients taking enalapril or losartan. 1999 Am. J. Hypertens. pmid:10480471
Zaitsu M et al. Induction of cytosolic phospholipase A2 and prostaglandin H2 synthase-2 by lipopolysaccharide in human polymorphonuclear leukocytes. 1999 Eur. J. Haematol. pmid:10480288
Fujimoto Y et al. Sphingomyelin inhibits platelet 12-lipoxygenase activity. 1999 Eur. J. Pharmacol. pmid:10478636
Li D et al. The association of diet and thrombotic risk factors in healthy male vegetarians and meat-eaters. 1999 Eur J Clin Nutr pmid:10477247
Gurbel PA et al. Plasma thromboxane and prostacyclin are linear related and increased in patients presenting with acute myocardial infarction. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10477035
Feldman M and Cryer B Aspirin absorption rates and platelet inhibition times with 325-mg buffered aspirin tablets (chewed or swallowed intact) and with buffered aspirin solution. 1999 Am. J. Cardiol. pmid:10468077
Hino Y et al. Changes in endothelium-derived vascular regulatory factors during dobutamine-stress-induced silent myocardial ischemia in patients with Kawasaki disease. 1999 Jpn. Circ. J. pmid:10462014
Jiménez R et al. Involvement of thromboxane A2 in the endothelium-dependent contractions induced by myricetin in rat isolated aorta. 1999 Br. J. Pharmacol. pmid:10455307
Sheu JR et al. The antiplatelet activity of PMC, a potent alpha-tocopherol analogue, is mediated through inhibition of cyclo-oxygenase. 1999 Br. J. Pharmacol. pmid:10455267
Melton SM et al. Mediator-dependent secondary injury after unilateral blunt thoracic trauma. 1999 Shock pmid:10454828
Arakida Y et al. Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs. 1999 J. Pharmacol. Exp. Ther. pmid:10454505
Zhang S et al. Effects of acupuncture on the levels of endothelin, TXB2, and 6-keto-PGF1 alpha in apoplexy patients. 1999 J Tradit Chin Med pmid:10453582
Ogura S et al. Protective effect of tyrphostin AG-556 on shock induced by endotoxin or gram positive bacteria. 1999 Shock pmid:10446890
Licker M et al. Chronic angiotensin converting inhibition does not influence renal hemodynamic and function during cardiac surgery. 1999 Can J Anaesth pmid:10442956
Tsugawa K et al. A selective cyclo-oxygenase-2 inhibitor, NS-398, may improve portal hypertension without inducing gastric mucosal injury. 1999 J. Gastroenterol. Hepatol. pmid:10440208
Ricetti MM et al. Effects of sodium selenite on in vitro interactions between platelets and endothelial cells. 1999 Int. J. Clin. Lab. Res. pmid:10436266
van Kooten F et al. Increased thromboxane biosynthesis is associated with poststroke dementia. 1999 Stroke pmid:10436098
Kim HS et al. Effects of tetrandrine and fangchinoline on human platelet aggregation and thromboxane B2 formation. 1999 J Ethnopharmacol pmid:10433485
Mills JL et al. Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. 1999 JAMA pmid:10432033
Hamberg M et al. A method for measurement of platelet regeneration in man. 1978 Prostaglandins Med pmid:104315
McCowan LM et al. Administration of low-dose aspirin to mothers with small for gestational age fetuses and abnormal umbilical Doppler studies to increase birthweight: a randomised double-blind controlled trial. 1999 Br J Obstet Gynaecol pmid:10428519
Kawano K et al. Superiority of platelet integrin GPIIb-IIIa receptor antagonist over aspirin in preventing cyclic flow reductions in the guinea pig middle cerebral artery. 1999 Eur. J. Pharmacol. pmid:10422782
Mercer JB et al. The effect of short-term cold exposure on risk factors for cardiovascular disease. 1999 Thromb. Res. pmid:10418798
Morrow JD et al. Increased formation of thromboxane in vivo in humans with mastocytosis. 1999 J. Invest. Dermatol. pmid:10417625
Jönsson A et al. Effects of amide local anaesthetics on eicosanoid formation in burned skin. 1999 Acta Anaesthesiol Scand pmid:10408815
Shen AY et al. Inhibition of 2-P-mercaptophenyl-1,4-naphthoquinone on human platelet function. 1999 Life Sci. pmid:10403492
Saareks V et al. Nicotinic acid and pyridoxine modulate arachidonic acid metabolism in vitro and ex vivo in man. 1999 Pharmacol. Toxicol. pmid:10401729
Peredo HA et al. Time-course of the alterations in prostanoid production and in contractile responses of mesenteric beds isolated from streptozotocin diabetic rats. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10397409
Bowers W et al. Artificial human skin: cytokine, prostaglandin, Hsp70 and histological responses to heat exposure. 1999 J. Dermatol. Sci. pmid:10397388
Maitra SR et al. Alterations in hepatic gluconeogenesis, prostanoid, and intracellular calcium during sepsis. 1999 Acad Emerg Med pmid:10386675
Itasaka H et al. The mechanism of hepatic graft protection against reperfusion injury by prostaglandin E1. 1999 Surg. Today pmid:10385367
Brown N et al. Comparison of antiplatelet activity of microencapsulated aspirin 162.5 Mg (Caspac XL), with enteric coated aspirin 75 mg and 150 mg in patients with atherosclerosis. 1999 Br J Clin Pharmacol pmid:10383561
Williams CA et al. The flavonoids of Tanacetum parthenium and T. vulgare and their anti-inflammatory properties. 1999 Phytochemistry pmid:10382317
Kubo K et al. A 21-aminosteroid, U-74006F, attenuates endotoxin-induced lung injury in awake sheep. 1999 Respirology pmid:10382236
Cryer B and Feldman M Effects of very low dose daily, long-term aspirin therapy on gastric, duodenal, and rectal prostaglandin levels and on mucosal injury in healthy humans. 1999 Gastroenterology pmid:10381905
Freedman JE et al. Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene. 1999 Circ. Res. pmid:10381894
Panara MR et al. Dose-dependent inhibition of platelet cyclooxygenase-1 and monocyte cyclooxygenase-2 by meloxicam in healthy subjects. 1999 J. Pharmacol. Exp. Ther. pmid:10381787
Walsh SW et al. AA-2414, an antioxidant and thromboxane receptor blocker, completely inhibits peroxide-induced vasoconstriction in the human placenta. 1999 J. Pharmacol. Exp. Ther. pmid:10381779
Tanaka H et al. Leukotriene (LT)-receptor antagonist is more effective in asthmatic patients with a low baseline ratio of urinary LTE4 to 2,3-dinor-6-keto-prostaglandin (PG)F1alpha. 1999 Allergy pmid:10380781