| MeSH term | MeSH ID | Detail |
|---|---|---|
| Bronchopulmonary Sequestration | D001998 | 3 associated lipids |
| Airway Remodeling | D056151 | 3 associated lipids |
| Varicose Veins | D014648 | 7 associated lipids |
| Tachycardia, Paroxysmal | D013614 | 2 associated lipids |
| Tachycardia, Supraventricular | D013617 | 3 associated lipids |
| Macular Edema | D008269 | 3 associated lipids |
| Aortic Rupture | D001019 | 3 associated lipids |
| Hypoalphalipoproteinemias | D052456 | 5 associated lipids |
| Diseases in Twins | D004200 | 4 associated lipids |
| Pulmonary Heart Disease | D011660 | 2 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Michibayashi T | Platelet aggregation and vasoconstriction related to platelet cyclooxygenase and 12-lipoxygenase pathways. | 2005 | J. Atheroscler. Thromb. | pmid:16020916 |
| Svenstrup Poulsen T et al. | A critical appraisal of the phenomenon of aspirin resistance. | 2005 | Cardiology | pmid:16020925 |
| Walsh DS et al. | Characterization of circulating monocytes expressing HLA-DR or CD71 and related soluble factors for 2 weeks after severe, non-thermal injury. | 2005 | J. Surg. Res. | pmid:16045935 |
| Rodrigue ME et al. | Cyclooxygenase inhibition with acetylsalicylic acid unmasks a role for prostacyclin in erythropoietin-induced hypertension in uremic rats. | 2005 | Can. J. Physiol. Pharmacol. | pmid:16049546 |
| Esser R et al. | Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2. | 2005 | Br. J. Pharmacol. | pmid:15655513 |
| Sullivan JC et al. | Sexual dimorphism in renal production of prostanoids in spontaneously hypertensive rats. | 2005 | Hypertension | pmid:15699443 |
| Chan CP et al. | Inhibition of cyclooxygenase activity, platelet aggregation and thromboxane B2 production by two environmental toxicants: m- and o-cresol. | 2005 | Toxicology | pmid:15664436 |
| Massicot F et al. | In vitro assessment of renal toxicity and inflammatory events of two protein phosphatase inhibitors cantharidin and nor-cantharidin. | 2005 | Basic Clin. Pharmacol. Toxicol. | pmid:15667592 |
| Vangroenweghe F et al. | Effect of carprofen treatment following experimentally induced Escherichia coli mastitis in primiparous cows. | 2005 | J. Dairy Sci. | pmid:15956299 |
| Wakamoto S et al. | Effects of hemoglobin vesicles on resting and agonist-stimulated human platelets in vitro. | 2005 | Artif Cells Blood Substit Immobil Biotechnol | pmid:15960075 |
| Al Kadi H et al. | A prospective, longitudinal study of the renin-angiotensin system, prostacyclin and thromboxane in the first trimester of normal human pregnancy: association with birthweight. | 2005 | Hum. Reprod. | pmid:16006463 |
| Beretta C et al. | COX-1 and COX-2 inhibition in horse blood by phenylbutazone, flunixin, carprofen and meloxicam: an in vitro analysis. | 2005 | Pharmacol. Res. | pmid:15939622 |
| Klein Gunnewiek JM et al. | The influence of acetylsalicylic acid intake by healthy volunteers on duplicate PFA-100 measurements. | 2005 | Blood Coagul. Fibrinolysis | pmid:15970717 |
| Visioli F et al. | Virgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients. | 2005 | Eur J Nutr | pmid:15309433 |
| Jin YR et al. | Antiplatelet activity of J78 (2-Chloro-3-[2'-bromo, 4'-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), an antithrombotic agent, is mediated by thromboxane (TX) A2 receptor blockade with TXA2 synthase inhibition and suppression of cytosolic Ca2+ mobilization. | 2005 | J. Pharmacol. Exp. Ther. | pmid:15328379 |
| Jermany J et al. | Lumiracoxib does not affect the ex vivo antiplatelet aggregation activity of low-dose aspirin in healthy subjects. | 2005 | J Clin Pharmacol | pmid:16172182 |
| Persico N et al. | Transdermal HRT and Doppler findings in normotensive and hypertensive postmenopausal patients. | 2005 | Ultrasound Obstet Gynecol | pmid:16184506 |
| Perini JA et al. | Influence of CYP2C9 genotypes on the pharmacokinetics and pharmacodynamics of piroxicam. | 2005 | Clin. Pharmacol. Ther. | pmid:16198655 |
| Davì G et al. | Helicobacter pylori infection causes persistent platelet activation in vivo through enhanced lipid peroxidation. | 2005 | Arterioscler. Thromb. Vasc. Biol. | pmid:15472127 |
| Maree AO et al. | Platelet response to low-dose enteric-coated aspirin in patients with stable cardiovascular disease. | 2005 | J. Am. Coll. Cardiol. | pmid:16198840 |
| Kataoka M et al. | A long-acting prostacyclin agonist with thromboxane inhibitory activity for pulmonary hypertension. | 2005 | Am. J. Respir. Crit. Care Med. | pmid:16192456 |
| Munsterhjelm E et al. | Dose-dependent inhibition of platelet function by acetaminophen in healthy volunteers. | 2005 | Anesthesiology | pmid:16192763 |
| Hsiao G et al. | Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. | 2005 | J. Lab. Clin. Med. | pmid:16194683 |
| Xiaorong C et al. | Effects of medicinal cake-separated moxibustion on plasma 6-keto-PGF1alpha and TXB2 contents in the rabbit of hyperlipemia. | 2005 | J Tradit Chin Med | pmid:16136949 |
| Trebino CE et al. | Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. | 2005 | J. Biol. Chem. | pmid:15722356 |
| De Candia E et al. | Abnormal pH-sensing of platelet Na+/H+ exchanger in patients with cardiac syndrome X. | 2005 | Int. J. Cardiol. | pmid:15837078 |
| Capone ML et al. | Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects. | 2005 | J. Am. Coll. Cardiol. | pmid:15837265 |
| Oliveira RL et al. | Postmenopausal hormone replacement therapy increases plasmatic thromboxane beta 2. | 2005 | Int. J. Cardiol. | pmid:15771927 |
| Cryer B et al. | Double-blind, randomized, parallel, placebo-controlled study of ibuprofen effects on thromboxane B2 concentrations in aspirin-treated healthy adult volunteers. | 2005 | Clin Ther | pmid:15811481 |
| Watanabe H et al. | Effects of salt loading on blood pressure in mice lacking the prostanoid receptor gene. | 2005 | Circ. J. | pmid:15635218 |
| Chang Y et al. | Mechanisms involved in the antiplatelet activity of ketamine in human platelets. | 2004 Nov-Dec | J. Biomed. Sci. | pmid:15591773 |
| Barrière G et al. | PHGPx overexpression induces an increase in COX-2 activity in colon carcinoma cells. | 2004 May-Jun | Anticancer Res. | pmid:15274299 |
| Persico N et al. | Transdermal hormone replacement therapy and Doppler findings in normal and overweight postmenopausal patients. | 2004 | Gynecol. Endocrinol. | pmid:15726916 |
| He J et al. | Treatment of unstable angina pectoris with modified nuan gan jian--a report of 33 cases. | 2004 | J Tradit Chin Med | pmid:15688691 |
| Arruzazabala ML et al. | Effects of d-003, a new substance purified from sugar cane wax, on platelet aggregation and plasma levels of arachidonic acid metabolites in healthy volunteers. | 2004 | Int J Clin Pharmacol Res | pmid:15689052 |
| Gross GJ and Moore J | Effect of COX-1/COX-2 inhibition versus selective COX-2 inhibition on coronary vasodilator responses to arachidonic acid and acetylcholine. | 2004 | Pharmacology | pmid:15161995 |
| Suzuki N et al. | Quantitative liquid chromatography-tandem mass spectrometric analysis of 11-dehydro TXB2 in urine. | 2004 | Prostaglandins Other Lipid Mediat. | pmid:15165035 |
| Lam AN et al. | Effect of red clover isoflavones on cox-2 activity in murine and human monocyte/macrophage cells. | 2004 | Nutr Cancer | pmid:15456640 |
| Moriguchi A et al. | Antithrombotic effects of FK419, a novel nonpeptide platelet GPIIb/IIIa antagonist, in a guinea pig photochemically induced middle cerebral artery thrombosis model: comparison with ozagrel and argatroban. | 2004 | J. Pharmacol. Exp. Ther. | pmid:14634048 |
| Xu L et al. | [Effects of effective component from "qing kai ling" on endothelial cell of microvessel in MCAO rats]. | 2004 | Zhong Yao Cai | pmid:15376390 |
| Perneby C et al. | Prothrombotic responses to exercise are little influenced by clopidogrel treatment. | 2004 | Thromb. Res. | pmid:15381386 |
| Hennekens CH et al. | Terms and conditions: semantic complexity and aspirin resistance. | 2004 | Circulation | pmid:15381661 |
| Zhao GR et al. | [Clinical study on relationship between sluggishness of lung-defensive qi and levels of vasoactive intestinal polypeptide and thromboxane B2]. | 2004 | Zhong Xi Yi Jie He Xue Bao | pmid:15383251 |
| Fiorucci S et al. | Co-administration of nitric oxide-aspirin (NCX-4016) and aspirin prevents platelet and monocyte activation and protects against gastric damage induced by aspirin in humans. | 2004 | J. Am. Coll. Cardiol. | pmid:15358033 |
| Ming HX et al. | [Influence of single leaf Asarum himalaicum on renal function of rabbits]. | 2004 | Zhong Xi Yi Jie He Xue Bao | pmid:15339444 |
| Dey A et al. | Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. | 2004 | Obes. Res. | pmid:15340111 |
| Sheu JR et al. | Expression of matrix metalloproteinase-9 in human platelets: regulation of platelet activation in in vitro and in vivo studies. | 2004 | Br. J. Pharmacol. | pmid:15289295 |
| Toth B et al. | Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. | 2004 | J. Appl. Physiol. | pmid:15298985 |
| Craft JA et al. | Increased platelet-derived microparticles in the coronary circulation of percutaneous transluminal coronary angioplasty patients. | 2004 | Blood Coagul. Fibrinolysis | pmid:15311156 |
| Devi MM and Das UN | Effect of prostaglandins against alloxan-induced cytotoxicity to insulin secreting insulinoma RIN cells in vitro. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15380818 |
| Ferroni P et al. | Platelet activation in type 2 diabetes mellitus. | 2004 | J. Thromb. Haemost. | pmid:15304032 |
| Di Nunno L et al. | Novel synthesis of 3,4-diarylisoxazole analogues of valdecoxib: reversal cyclooxygenase-2 selectivity by sulfonamide group removal. | 2004 | J. Med. Chem. | pmid:15369392 |
| Kojima F et al. | Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis. | 2004 | Arthritis Res. Ther. | pmid:15225371 |
| Farndale RW et al. | Measurement of platelet arachidonic acid metabolism. | 2004 | Methods Mol. Biol. | pmid:15226540 |
| Barbara J et al. | Inhaled cornstarch glove powder increases latex-induced airway hyper-sensitivity in guinea-pigs. | 2004 | Clin. Exp. Allergy | pmid:15196289 |
| Wu KJ et al. | [Detection of thromboxane B2, 6-keto-prostaglandin F1alpha and anticardiolipin antibody in patients with obstructive sleep apnea-hypopnea syndrome]. | 2004 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:15196341 |
| Van Ryn J et al. | Meloxicam does not affect the antiplatelet effect of aspirin in healthy male and female volunteers. | 2004 | J Clin Pharmacol | pmid:15199082 |
| Aikawa K et al. | Effects of antioxidants on coronary microvascular spasm induced by epicardial coronary artery endothelial injury in pigs. | 2004 | Coron. Artery Dis. | pmid:15201617 |
| Lorenzoni R et al. | Short-term prevention of thromboembolic complications in patients with atrial fibrillation with aspirin plus clopidogrel: the Clopidogrel-Aspirin Atrial Fibrillation (CLAAF) pilot study. | 2004 | Am. Heart J. | pmid:15215815 |
| Korkushko OV et al. | [Some mechanisms of the development of endothelial disfunction in aging]. | 2004 | Fiziol Zh | pmid:15174205 |
| Kawano T et al. | Acetaldehyde induces histamine release from human airway mast cells to cause bronchoconstriction. | 2004 | Int. Arch. Allergy Immunol. | pmid:15178893 |
| Ishitsuka Y et al. | Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs. | 2004 | J. Pharm. Pharmacol. | pmid:15099446 |
| Zhang L et al. | Effects of thiol antioxidant on reduced nicotinamide adenine dinucleotide phosphate oxidase in hypertensive Dahl salt-sensitive rats. | 2004 | Free Radic. Biol. Med. | pmid:15528040 |
| Dinev D and Andonova M | The effect of general anesthesia and abdominal surgery upon plasma thromboxane B concentrations in horses. | 2004 | Vet Anaesth Analg | pmid:15053753 |
| Menzies-Gow NJ et al. | Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators. | 2004 | Equine Vet. J. | pmid:15147137 |
| Ghuysen A et al. | Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism. | 2004 | J. Pharmacol. Exp. Ther. | pmid:15121765 |
| Caprani A et al. | Experimental evidence of a potentially increased thrombo-embolic disease risk by domestic electromagnetic field exposure. | 2004 | Bioelectromagnetics | pmid:15114641 |
| Di Minno G and Violi F | Aspirin resistance and diabetic angiopathy: back to the future. | 2004 | Thromb. Res. | pmid:15115664 |
| Torsney E et al. | Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection. | 2004 | Circ. Res. | pmid:15117816 |
| Wang YY et al. | Inhibition of platelet aggregation by polyaspartoyl L-arginine and its mechanism. | 2004 | Acta Pharmacol. Sin. | pmid:15066215 |
| Park HS et al. | Dietary conjugated linoleic acid increases the mRNA ratio of Bax/Bcl-2 in the colonic mucosa of rats. | 2004 | J. Nutr. Biochem. | pmid:15068816 |
| Zhang C et al. | Inhibition of inflammation contributes to organ protection of atenolol in sinoaortic-denervated rats. | 2004 | J. Cardiovasc. Pharmacol. | pmid:15071353 |
| Bruno A et al. | Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction. | 2004 | Stroke | pmid:14963281 |
| Kwak SH et al. | Effects of propofol on endotoxin-induced acute lung injury in rabbit. | 2004 | J. Korean Med. Sci. | pmid:14966342 |
| Scott G et al. | Lumiracoxib: pharmacokinetic and pharmacodynamic profile when coadministered with fluconazole in healthy subjects. | 2004 | J Clin Pharmacol | pmid:14747429 |
| Arrebola MM et al. | In vitro effects of clopidogrel on the platelet-subendothelium interaction, platelet thromboxane and endothelial prostacyclin production, and nitric oxide synthesis. | 2004 | J. Cardiovasc. Pharmacol. | pmid:14668571 |
| Freitas CF et al. | Role of endothelin-1 and thromboxane A2 in the pulmonary hypertension induced by heparin-protamine interaction in anesthetized dogs. | 2004 | J. Cardiovasc. Pharmacol. | pmid:14668575 |
| Park WH et al. | Anti-inflammatory effects of a traditional Korean herbal formulation, Silsosangami, consisting of seven medicinal herbs: effect on hemolysis, neutrophil function, and gene expressions of iNOS and COX-2. | 2004 | Vascul. Pharmacol. | pmid:15664882 |
| Vainio M et al. | Prostacyclin, thromboxane A and the effect of low-dose ASA in pregnancies at high risk for hypertensive disorders. | 2004 | Acta Obstet Gynecol Scand | pmid:15548142 |
| Franz KB | A functional biological marker is needed for diagnosing magnesium deficiency. | 2004 | J Am Coll Nutr | pmid:15637224 |
| Cardoni RL and Antúnez MI | Circulating levels of cyclooxygenase metabolites in experimental Trypanosoma cruzi infections. | 2004 | Mediators Inflamm. | pmid:15545053 |
| Wu JX et al. | Changes in somatostatin receptor expression of the pancreas and effectiveness of octreotide in rats with acute necrotizing pancreatitis. | 2004 | Chin J Dig Dis | pmid:15612670 |
| Berrougui H et al. | Argan (Argania spinosa) oil lowers blood pressure and improves endothelial dysfunction in spontaneously hypertensive rats. | 2004 | Br. J. Nutr. | pmid:15613254 |
| Fan JG et al. | [Dynamic changes of plasma levels of prostacycline and thromboxane A2 and their correlation with the severity of hepatic injury in rats with nonalcoholic fatty liver disease]. | 2004 | Zhonghua Gan Zang Bing Za Zhi | pmid:15623379 |
| Tsai CY et al. | Proinflammatory cytokines enhance COX-1 gene expression in cultured rat glomerular mesangial cells. | 2004 | Int. Immunopharmacol. | pmid:14975359 |
| Smalling WE et al. | Protective effect of pentoxifylline on volume-induced lung injury in newborn piglets. | 2004 | Biol. Neonate | pmid:14981352 |
| Ikonomidis I et al. | Reduction of daily life ischaemia by aspirin in patients with angina: underlying link between thromboxane A2 and macrophage colony stimulating factor. | 2004 | Heart | pmid:15020512 |
| Dippel DW et al. | What is the lowest dose of aspirin for maximum suppression of in vivo thromboxane production after a transient ischemic attack or ischemic stroke? | 2004 | Cerebrovasc. Dis. | pmid:15026612 |
| Vega-Ostertag M et al. | Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin. | 2004 | Arthritis Rheum. | pmid:15457460 |
| Noverr MC and Huffnagle GB | Regulation of Candida albicans morphogenesis by fatty acid metabolites. | 2004 | Infect. Immun. | pmid:15501745 |
| Tanigawa T et al. | Anti-inflammatory effect of two isoforms of COX in H. pylori-induced gastritis in mice: possible involvement of PGE2. | 2004 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12958020 |
| Rocca B et al. | Modulation of the expression and activity of cyclooxygenases in normal and accelerated erythropoiesis. | 2004 | Exp. Hematol. | pmid:15504548 |
| Chou DS et al. | Low concentration of oxidized low density lipoprotein suppresses platelet reactivity in vitro: an intracellular study. | 2004 | Lipids | pmid:15506238 |
| He W et al. | Effects of the Chinese drugs for activating blood circulation on plasma TXB2 and 6-keto-PGF1alpha contents in rabbits with glucocorticoid-induced femoral head necrosis. | 2004 | J Tradit Chin Med | pmid:15510809 |
| Chiang N et al. | Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15471991 |
| Park WH et al. | Inhibitory effect of GBH on platelet aggregation through inhibition of intracellular Ca2+ mobilization in activated human platelets. | 2004 | Life Sci. | pmid:15474558 |
| Chen BN et al. | [Characteristic changes of vascular tension factors in diabetic arterial occlusion of lower extremities]. | 2004 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:15495823 |
| Horani MH et al. | Cyclooxygenase inhibition is associated with downregulation of apolipoprotein AI promoter activity in cultured hepatoma cell line HepG2. | 2004 | Metab. Clin. Exp. | pmid:14767868 |
| Kawada N et al. | TP receptors regulate renal hemodynamics during angiotensin II slow pressor response. | 2004 | Am. J. Physiol. Renal Physiol. | pmid:15213069 |
| Peck OM et al. | Staphylococcus aureus and lipopolysaccharide induce homologous tolerance but heterologous priming: role of interferon-gamma. | 2004 | Shock | pmid:14770039 |