| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Duan M et al. | Factors involved in the neuronal death during postischemic reperfusion: experimental study in rabbits. | 1999 | Chin. Med. J. | pmid:11593584 |
| MacKay RJ et al. | Effect of a conjugate of polymyxin B-dextran 70 in horses with experimentally induced endotoxemia. | 1999 | Am. J. Vet. Res. | pmid:9918150 |
| Fredenrich A et al. | Effects of low density and high density lipoproteins isolated from non-insulin dependent diabetic patients on prostaglandin secretion by mouse macrophage cell line P388D1. | 1999 | Atherosclerosis | pmid:9920525 |
| Licker M et al. | Chronic angiotensin converting inhibition does not influence renal hemodynamic and function during cardiac surgery. | 1999 | Can J Anaesth | pmid:10442956 |
| Tegeder I et al. | Comparison of inhibitory effects of meloxicam and diclofenac on human thromboxane biosynthesis after single doses and at steady state. | 1999 | Clin. Pharmacol. Ther. | pmid:10340919 |
| Stanczyk FZ et al. | Effect of oral contraceptives containing 20 and 35 micrograms ethinyl estradiol on urinary prostacyclin and thromboxane metabolite levels in smokers and nonsmokers. | 1999 | Contraception | pmid:10342082 |
| Mercer JB et al. | The effect of short-term cold exposure on risk factors for cardiovascular disease. | 1999 | Thromb. Res. | pmid:10418798 |
| Kawano K et al. | Superiority of platelet integrin GPIIb-IIIa receptor antagonist over aspirin in preventing cyclic flow reductions in the guinea pig middle cerebral artery. | 1999 | Eur. J. Pharmacol. | pmid:10422782 |
| Dirig DM and Yaksh TL | In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin. | 1999 | Br. J. Pharmacol. | pmid:10217526 |
| Dong Y et al. | [Quantitive study of 6-keto-prostaglandin F1 alpha and thromboxane B2 in human pulp]. | 1999 | Zhonghua Kou Qiang Yi Xue Za Zhi | pmid:11776916 |
| Saareks V et al. | Nicotinic acid and pyridoxine modulate arachidonic acid metabolism in vitro and ex vivo in man. | 1999 | Pharmacol. Toxicol. | pmid:10401729 |
| McAdam BF et al. | Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9874808 |
| Mills JL et al. | Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. | 1999 | JAMA | pmid:10432033 |
| Fujimoto Y et al. | Sphingomyelin inhibits platelet 12-lipoxygenase activity. | 1999 | Eur. J. Pharmacol. | pmid:10478636 |
| Hu MK et al. | Synthesis and evaluation of backbone/amide-modified analogs of leualacin. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10098664 |
| Yamamoto T et al. | Production of prostanoids and nitric oxide by infarcted heart in situ and the effect of aspirin. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10198239 |
| Mayer AM et al. | Escherichia coli lipopolysaccharide potentiation and inhibition of rat neonatal microglia superoxide anion generation: correlation with prior lactic dehydrogenase, nitric oxide, tumor necrosis factor-alpha, thromboxane B2, and metalloprotease release. | 1999 | Shock | pmid:10188770 |
| Yang SY and Gao ZX | Determination and clinical significance of plasma levels of prostaglandins in patients with acute brain injury. | 1999 | Surg Neurol | pmid:10511080 |
| Kay-Mugford T and Conlon P | Possible inconsistencies in study on cyclooxygenase. | 1999 | Am. J. Vet. Res. | pmid:10188806 |
| Davì G et al. | In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation. | 1999 | Circulation | pmid:9892587 |
| de Meijer A et al. | Meloxicam, 15 mg/day, spares platelet function in healthy volunteers. | 1999 | Clin. Pharmacol. Ther. | pmid:10546927 |
| Reeves JH et al. | Continuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group. | 1999 | Crit. Care Med. | pmid:10548188 |
| Nemcova S et al. | Cyclic nucleotides and production of prostanoids in human varicose veins. | 1999 | J. Vasc. Surg. | pmid:10550185 |
| Hirakata H et al. | Propofol has both enhancing and suppressing effects on human platelet aggregation in vitro. | 1999 | Anesthesiology | pmid:10551587 |
| Heller A et al. | Pancreatitis-associated protein protects the lung from leukocyte-induced injury. | 1999 | Anesthesiology | pmid:10551593 |
| Peredo HA et al. | Time-course of the alterations in prostanoid production and in contractile responses of mesenteric beds isolated from streptozotocin diabetic rats. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10397409 |
| Hayashi N et al. | Effects of intravenous omega-3 and omega-6 fat emulsion on cytokine production and delayed type hypersensitivity in burned rats receiving total parenteral nutrition. | 1998 Nov-Dec | JPEN J Parenter Enteral Nutr | pmid:9829609 |
| Guimarães PC et al. | Variations in white blood count, thromboxane B2 levels and hematocrit in chronic venous hypertension. | 1998 May-Jun | Sao Paulo Med J | pmid:9876450 |
| RogovyÄ IuE | [Beta 2-microglobulin as a criterion of dysfunction in the regulation of proximal tubular activity in mercuric chloride-induced nephropathy]. | 1998 May-Jun | Urol Nefrol (Mosk) | pmid:9644989 |
| DeVries A et al. | Ketoconazole in the prevention of acute respiratory distress syndrome. | 1998 May-Jun | Pharmacotherapy | pmid:9620108 |
| Sheu JR et al. | Inhibitory mechanisms of naloxone on human platelets. | 1998 Jul-Aug | Clin. Exp. Pharmacol. Physiol. | pmid:9673433 |
| Carvalho C et al. | Inhibition of airway hyperreactivity, edema, and lung cell infiltration by compound U-83836E in sensitized guinea pigs. | 1998 Jul-Aug | Can. J. Physiol. Pharmacol. | pmid:10030451 |
| Moore RM et al. | Effect of platelet-activating factor antagonist L-691,880 on low-flow ischemia-reperfusion injury of the large colon in horses. | 1998 Jan-Feb | Vet Surg | pmid:9449176 |
| Hanaoka M et al. | Effect of post-treatment with granulocyte colony-stimulating factor on endotoxin-induced lung injury in sheep. | 1998 Jan-Feb | Exp. Lung Res. | pmid:9457466 |
| Kruse-Elliott KT et al. | Role of lipid-derived mediators in tumor necrosis factor-induced endothelin-1 release in vivo. | 1998 | Shock | pmid:9466472 |
| Smith CJ et al. | Pharmacological analysis of cyclooxygenase-1 in inflammation. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9789085 |
| Sheu JR et al. | Mechanisms involved in the antiplatelet activity of Escherichia coli lipopolysaccharide in human platelets. | 1998 | Br. J. Haematol. | pmid:9792285 |
| Obase Y et al. | Effects of cysteinyl-leukotriene receptor antagonist, thromboxane A2 receptor antagonist, and thromboxane A2 synthetase inhibitor on antigen-induced bronchoconstriction in patients with asthma. | 1998 | Chest | pmid:9792572 |
| Cullen L et al. | Selective cyclooxygenase-2 inhibition by nimesulide in man. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9808683 |
| Hellyer PW et al. | The effects of hyperoxia on the biosynthesis of cyclooxygenase products and haemodynamic response to nitric oxide synthase inhibition with L-NAME in endotoxaemic pigs. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9811434 |
| Dobner P and Engelmann B | Low-density lipoproteins supply phospholipid-bound arachidonic acid for platelet eicosanoid production. | 1998 | Am. J. Physiol. | pmid:9814996 |
| Provost P et al. | Platelets, neutrophils, and vasoconstriction after arterial injury by angioplasty in pigs: effects of MK-886, a leukotriene biosynthesis inhibitor. | 1998 | Br. J. Pharmacol. | pmid:9489613 |
| Brinkmann A et al. | Vasopressor hormone response following mesenteric traction during major abdominal surgery. | 1998 | Acta Anaesthesiol Scand | pmid:9773140 |
| Power I et al. | Effects of ketorolac and dextran-70 alone and in combination on haemostasis. | 1998 | Acta Anaesthesiol Scand | pmid:9773144 |
| Chavali SR et al. | Increased production of TNF-alpha and decreased levels of dienoic eicosanoids, IL-6 and IL-10 in mice fed menhaden oil and juniper oil diets in response to an intraperitoneal lethal dose of LPS. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774171 |
| Jain SK et al. | Relationship of blood thromboxane-B2 (TxB2) with lipid peroxides and effect of vitamin E and placebo supplementation on TxB2 and lipid peroxide levels in type 1 diabetic patients. | 1998 | Diabetes Care | pmid:9727900 |
| Gonchar MV et al. | Lack of direct connection between arachidonic acid release and prostanoid synthesis upon differentiation of U937 cell. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9731221 |
| Paarlberg KM et al. | Vasoactive mediators in pregnancy-induced hypertensive disorders: a longitudinal study. | 1998 | Am. J. Obstet. Gynecol. | pmid:9855596 |
| Xing X et al. | [Preserving remnant liver function after major hepatic vein occlusion]. | 1998 | Zhonghua Wai Ke Za Zhi | pmid:11825430 |
| Giardiello FM et al. | Prostaglandin levels in human colorectal mucosa: effects of sulindac in patients with familial adenomatous polyposis. | 1998 | Dig. Dis. Sci. | pmid:9512123 |
| Xing X and Xia S | Injury of liver sinusoidal endothelial cells in isolated liver perfusion model for regional chemotherapy in rats. | 1998 | Chin. Med. J. | pmid:10374437 |
| Ren YJ et al. | Inhibitory effects of nimodipine on platelet aggregation and thrombosis. | 1998 | Zhongguo Yao Li Xue Bao | pmid:10374642 |
| Shan CW et al. | Inhibitory effects of procainamide on rabbit platelet aggregation and thromboxane B2 production in vitro. | 1998 | Zhongguo Yao Li Xue Bao | pmid:10374644 |
| Liao CH et al. | Effect of PP1D-1, a synthetic antiplatelet compound, on rabbit platelets. | 1998 | Jpn. J. Pharmacol. | pmid:9541276 |
| González E et al. | Nitric oxide modulates placental prostanoid production from late pregnant non-insulin-dependent diabetic rat. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9888203 |
| Zhao S et al. | Glioma prostaglandin levels correlate with brain edema. | 1998 | J. Tongji Med. Univ. | pmid:10806839 |
| Dschietzig T et al. | Coronary constriction and consequent cardiodepression in pulmonary embolism are mediated by pulmonary big endothelin and enhanced in early endothelial dysfunction. | 1998 | Crit. Care Med. | pmid:9504580 |
| Hu DH | [Effects of taurine enhancement of synthesis of TxA2 and PGI2 in cultured intra-pulmonary arteriolar smooth muscle cells under acute hypoxia]. | 1998 | Sheng Li Xue Bao | pmid:11324559 |
| Ooi BS et al. | Stimulation of endothelial cell production of vasoconstrictive substances by hypertensive sera. | 1998 | Am. J. Hypertens. | pmid:9524055 |
| Bons-Sicard C et al. | Localization and quantification of TXB2 in human healthy and inflammatory gingival mucosa. | 1998 | J. Periodont. Res. | pmid:9524318 |
| Fukushima C et al. | Effect of synthetase inhibitors and receptor antagonists in antigen-induced contraction of human lung parenchyma. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9532973 |
| Bagdasarian A et al. | IVIG adverse reactions: potential role of cytokines and vasoactive substances. | 1998 | Vox Sang. | pmid:9501404 |
| Kosugi T et al. | Glomerular thromboxane contributes to pressor response in deoxycorticosterone acetate-salt hypertension. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9578151 |
| Failli P et al. | Effect of some cyclooxygenase inhibitors on the increase in guanosine 3':5'-cyclic monophosphate induced by NO-donors in human whole platelets. | 1998 | Br. J. Pharmacol. | pmid:9579743 |
| Hwang GS et al. | Effects of Brazilin on the phospholipase A2 activity and changes of intracellular free calcium concentration in rat platelets. | 1998 | Arch. Pharm. Res. | pmid:9868555 |
| Chang MC et al. | Antithrombotic effect of crotalin, a platelet membrane glycoprotein Ib antagonist from venom of Crotalus atrox. | 1998 | Blood | pmid:9473223 |
| Snapper JR et al. | Role of endothelin in endotoxin-induced sustained pulmonary hypertension in sheep. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9445282 |
| Whiteford M et al. | Effect of liposome-encapsulated hemoglobin on the development of endotoxin-induced shock in the rat. | 1998 | Shock | pmid:9645495 |
| Mainwaring RD et al. | Complement activation and cytokine generation after modified Fontan procedure. | 1998 | Ann. Thorac. Surg. | pmid:9647087 |
| van den Dorpel MA et al. | Forearm vasorelaxation in hypertensive renal transplant patients: the impact of withdrawal of cyclosporine. | 1998 | J. Hypertens. | pmid:9557926 |
| Assaley J et al. | Effects of magnesium sulfate infusion upon clotting parameters in patients with pre-eclampsia. | 1998 | J Perinat Med | pmid:9650132 |
| Parra T et al. | Cyclosporine A nephrotoxicity: role of thromboxane and reactive oxygen species. | 1998 | J. Lab. Clin. Med. | pmid:9452128 |
| Nagao T et al. | Effect of lipo-prostaglandin E1 on crescentic-type anti-glomerular basement membrane nephritis in rats. | 1998 | Eur. J. Pharmacol. | pmid:9650829 |
| Harada Y et al. | Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat. | 1998 | Prostaglandins Other Lipid Mediat. | pmid:9653772 |
| Bordia A et al. | Effect of garlic (Allium sativum) on blood lipids, blood sugar, fibrinogen and fibrinolytic activity in patients with coronary artery disease. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9654398 |
| Durando MM et al. | Endotoxin activation of mitogen-activated protein kinase in THP-1 cells; diminished activation following endotoxin desensitization. | 1998 | J. Leukoc. Biol. | pmid:9715266 |
| Takami M and Tsukada W | Correlative alteration of thromboxane A2 with antigen-induced bronchoconstriction and the role of platelets as a source of TXA2 synthesis in guinea pigs: effect of DP-1904, an inhibitor of thromboxane synthetase. | 1998 | Pharmacol. Res. | pmid:9721601 |
| Takami M and Tsukada W | In vitro effect of DP-1904, a novel anti-asthma agent, against antigen-induced constriction and TXB2 release from the isolated guinea-pig lung parenchymal tissue. | 1998 | Pharmacol. Res. | pmid:9721602 |
| Levy M et al. | Cerebrospinal fluid prostaglandins after systemic dipyrone intake. | 1998 | Clin. Pharmacol. Ther. | pmid:9695726 |
| Fagugli RM et al. | Reduction of renal functional reserve in kidney transplant recipients: a possible role of arachidonic acid metabolism alterations. | 1998 | Clin. Nephrol. | pmid:9696430 |
| Iida T et al. | The effects of a thromboxane A2 synthesis inhibitor and a prostaglandin I2 analogue on experimental acute necrotizing pancreatitis in rats. | 1998 | Pancreas | pmid:9700944 |
| Bernareggi M et al. | Bronchopulmonary effects of 8-epi-PGF2A in anaesthetised guinea pigs. | 1998 | Pharmacol. Res. | pmid:9503483 |
| Dent G et al. | Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils. | 1998 | Am. J. Respir. Cell Mol. Biol. | pmid:9448055 |
| Larsen LN et al. | Alpha- and beta- alkyl-substituted eicosapentaenoic acids: incorporation into phospholipids and effects on prostaglandin H synthase and 5-lipoxygenase. | 1998 | Biochem. Pharmacol. | pmid:9514074 |
| Akarsu ES et al. | Effect of ciliary neurotrophic factor on body temperature and cerebrospinal fluid prostanoids in the cat. | 1998 | Brain Res. Bull. | pmid:9434196 |
| Zeng W et al. | [Relationship between PGI2, TXA2 and threatened preterm]. | 1998 | Hua Xi Yi Ke Da Xue Xue Bao | pmid:10684102 |
| Fadok VA et al. | Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. | 1998 | J. Clin. Invest. | pmid:9466984 |
| Alanko J et al. | Catechol estrogens as inhibitors of leukotriene synthesis. | 1998 | Biochem. Pharmacol. | pmid:9413936 |
| Stadelmann WK et al. | Aprotinin in ischemia-reperfusion injury: flap survival and neutrophil response in a rat skin flap model. | 1998 | Microsurgery | pmid:9846997 |
| Inoue H et al. | Changes in endothelin-1, 6-keto-PG-F1 alpha, and TX-B2 in random pattern flaps. | 1998 | J. Cardiovasc. Pharmacol. | pmid:9595517 |
| Fuse S et al. | Plasma thromboxane B2 concentration in patients with ventricular septal defect and pulmonary hypertension. | 1998 | Jpn. Circ. J. | pmid:9583446 |
| Heller DA et al. | Mortality and biomarkers of aging in heterogeneous stock (HS) mice. | 1998 | J. Gerontol. A Biol. Sci. Med. Sci. | pmid:9597046 |
| Jiang XW et al. | Effects of low-dose Beraprost sodium, a stable prostaglandin I2 analogue, on reperfusion injury to rabbit lungs. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9817723 |
| Erez E et al. | Thromboxane production in human lung during cardiopulmonary bypass: beneficial effect of aspirin? | 1998 | Ann. Thorac. Surg. | pmid:9456103 |
| Chiba Y et al. | Effects of depletion of leukocytes and platelets on cardiac dysfunction after cardiopulmonary bypass. | 1998 | Ann. Thorac. Surg. | pmid:9456104 |
| Robbins DL et al. | Effect of anticardiolipin/beta2-glycoprotein I complexes on production of thromboxane A2 by platelets from patients with the antiphospholipid syndrome. | 1998 | J. Rheumatol. | pmid:9458202 |
| Forastiero R et al. | Anti-beta2 glycoprotein I antibodies and platelet activation in patients with antiphospholipid antibodies: association with increased excretion of platelet-derived thromboxane urinary metabolites. | 1998 | Thromb. Haemost. | pmid:9459320 |
| Keen HL et al. | Maintenance of baseline angiotensin II potentiates insulin hypertension in rats. | 1998 | Hypertension | pmid:9461234 |
| Takami M and Tsukada W | Effects of DP-1904, a thromboxane synthetase inhibitor, on the antigen-induced airway hyperresponsiveness and infiltration of inflammatory cells in guinea-pigs. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10102387 |
| Henry A et al. | Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein. | 1998 | Br. J. Haematol. | pmid:9827912 |