| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mäkilä UM et al. | Regulation of prostacyclin and thromboxane production by human umbilical vessels: the effect of estradiol and progesterone in a superfusion model. | 1982 | Prostaglandins Leukot Med | pmid:7043492 |
| Han P et al. | Inhibition of platelet function of antiarrhythmic drugs, verapamil and disopyramide. | 1982 | Thromb. Haemost. | pmid:7101234 |
| Krausz MM et al. | Adverse effects of prostacyclin used to perfuse isolated lung lobes. | 1982 | Am. J. Physiol. | pmid:7044149 |
| Hirsh PD et al. | Influence of blood sampling site and technique on thromboxane concentrations in patients with ischemic heart disease. | 1982 | Am. Heart J. | pmid:7102506 |
| Chierchia S et al. | Failure of thromboxane A2 blockade to prevent attacks of vasospastic angina. | 1982 | Circulation | pmid:7116586 |
| Sasagawa S et al. | Effects of thromboxane A2 injection on the rabbit coronary artery. I. Physiologic effects in healthy animals. | 1982 | Exp. Mol. Pathol. | pmid:7117494 |
| Fantone JC et al. | Inhibition of vascular permeability changes in rats by captopril. | 1982 | J. Clin. Invest. | pmid:6282931 |
| Ylikorkala O and Viinikka L | Effect of amnioscopy on concentrations of prostaglandin F2 alpha, prostacyclin and thromboxane in maternal plasma. | 1982 | Gynecol. Obstet. Invest. | pmid:6954125 |
| Dorsch W et al. | Mediator studies in skin blister fluid from patients with dual skin reactions after intradermal allergen injection. | 1982 | J. Allergy Clin. Immunol. | pmid:6181112 |
| Fletcher MS et al. | Endotoxin, prostaglandins and renal fibrin deposition in obstructive jaundice. | 1982 | Br J Surg | pmid:6751458 |
| Shaw JO and Lyons RM | Requirement for different Ca2+ pools in the activation of rabbit platelets II. Phospholipase activity. | 1982 | Biochim. Biophys. Acta | pmid:6800410 |
| Dejana E et al. | Bleeding time in rats: a comparison of different experimental conditions. | 1982 | Thromb. Haemost. | pmid:6753230 |
| Strano A et al. | Platelet sensitivity to prostacyclin and thromboxane production in hyperlipidemic patients. | 1982 | Thromb. Haemost. | pmid:6753232 |
| Flynn JT and Demling RH | Inhibition of endogenous thromboxane synthesis by exogenous prostacyclin during endotoxemia in conscious sheep. | 1982 | Adv Shock Res | pmid:6753534 |
| Zipser RD and Martin K | Urinary excretion of arterial blood prostaglandins and thromboxanes in man. | 1982 | Am. J. Physiol. | pmid:6950668 |
| Watanabe T et al. | Characterization of the biosynthetic pathway of prostaglandin D2 in human platelet-rich plasma. | 1982 | J. Biol. Chem. | pmid:6816798 |
| Reines HD et al. | Plasma thromboxane concentrations are raised in patients dying with septic shock. | 1982 | Lancet | pmid:6123885 |
| White JG and Rao GH | Effects of a microtubule stabilizing agent on the response of platelets to vincristine. | 1982 | Blood | pmid:6124288 |
| Chong BH et al. | Heparin-induced thrombocytopenia: association of thrombotic complications with heparin-dependent IgG antibody that induces thromboxane synthesis in platelet aggregation. | 1982 | Lancet | pmid:6128550 |
| Di Minno G et al. | Arachidonic acid induces human platelet-fibrin retraction: the role of platelet cyclic endoperoxides. | 1982 | Thromb. Res. | pmid:6803385 |
| Suehiro A et al. | The role of platelet hyperfunction in thrombus formation in hyperlipidemia. | 1982 | Thromb. Res. | pmid:6803387 |
| Nolan RD et al. | The pericardium as a source of prostacyclin in the dog, ox and rat. | 1982 | Prostaglandins | pmid:6820168 |
| Davì G et al. | [Effects of flurbiprofen on platelet function in patients with ischemic cardiomyopathy]. | 1982 | Cardiologia | pmid:6927457 |
| Patrignani P et al. | Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects. | 1982 | J. Clin. Invest. | pmid:7045161 |
| Neri Serheri GG et al. | Platelet aggregation and thromboxane A2 production after adrenergic stimulation in young healthy humans. | 1982 | Haemostasis | pmid:6279476 |
| Watkins WD et al. | Thromboxane and pulmonary hypertension following E. coli endotoxin infusion in sheep: effect of an imidazole derivative. | 1982 | Prostaglandins | pmid:7048422 |
| Dore-Duffy P | Differential effect of prostaglandins and other products of arachidonic acid metabolism on measles virus replication in Vero cells. | 1982 | Prostaglandins Leukot Med | pmid:6281810 |
| Miller OV et al. | Acetyl glycerylphosphorylcholine inhibition of prostaglandin I2-stimulated adenosine 3',5'-cyclic monophosphate levels in human platelets. Evidence for thromboxane A2 dependence. | 1982 | Biochim. Biophys. Acta | pmid:6285985 |
| Kunkel SL et al. | Production of cyclooxygenase products and superoxide anion by macrophages in response to chemotactic factors. | 1982 | Prostaglandins | pmid:6300969 |
| Panossian A et al. | On the mechanism of biosynthesis of leukotrienes and related compounds. | 1982 | FEBS Lett. | pmid:6297982 |
| Pawlowski NA et al. | Uptake and metabolism of monohydroxy-eicosatetraenoic acids by macrophages. | 1982 | J. Exp. Med. | pmid:6951919 |
| Scherhag R et al. | Dietary administration of eicosapentaenoic and linolenic acid increases arterial blood pressure and suppresses vascular prostacyclin synthesis in the rat. | 1982 | Prostaglandins | pmid:6285420 |
| Malemud CJ et al. | Correlation of the biosynthesis of prostaglandin and cyclic AMP in monolayer cultures of rabbit articular chondrocytes. | 1982 | Biochim. Biophys. Acta | pmid:6280776 |
| Ylikorkala O et al. | The effect of oral contraceptives on antiaggregatory prostacyclin and proaggregatory thromboxane A2 in humans. | 1982 | Am. J. Obstet. Gynecol. | pmid:7036746 |
| Uyama O et al. | Plasma concentrations of 6-keto-prostaglandin F1 alpha in patients with hypertension, cerebrovascular disease or Takayasu's arteritis. | 1982 Jan 1-15 | Thromb. Res. | pmid:6121391 |
| Sakai K et al. | Roles of endogenous prostacyclin and thromboxane A2 in the ischemic canine heart. | 1982 Jan-Feb | J. Cardiovasc. Pharmacol. | pmid:6176788 |
| Giannessi D et al. | Methodological assessment and applications of a radioimmunoassay for thromboxane (TxB2) to measurement of TxB2 release by platelets. | 1982 Jan-Mar | J. Nucl. Med. Allied Sci. | pmid:7108634 |
| Shohami E et al. | The effect of incomplete cerebral ischemia on prostaglandin levels in rat brain. | 1982 Jul-Aug | Stroke | pmid:6896589 |
| Mest HJ et al. | [Effect of stress on blood level of prostaglandins in students during exams]. | 1982 May-Jun | Farmakol Toksikol | pmid:7095121 |
| Svensson J and Samuelsson K | Inhibition of platelet function by low dose acetylsalicylic acid in patients with cerebrovascular disease. | 1983 | Thromb. Res. | pmid:20218005 |
| Saldeen P et al. | Increased synthesis of thromboxane B2 and 6-keto-PGF1 alpha in hand veins from patients with deep venous thrombosis. | 1983 | Thromb. Res. | pmid:6658723 |
| Menys VC and Davies JA | Inhibitory effects of ZK 36374, a stable prostacyclin analogue, on adhesion of rabbit platelets to damaged aorta and serotonin release by adherent platelets. | 1983 | Clin. Sci. | pmid:6190604 |
| Hartung HP and Toyka KV | Activation of macrophages by substance P: induction of oxidative burst and thromboxane release. | 1983 | Eur. J. Pharmacol. | pmid:6191998 |
| Tanganelli I et al. | [Thromboxane, beta-thromboglobulin and the degree of blood sugar control in type 1 diabetes mellitus]. | 1983 | Boll. Soc. Ital. Biol. Sper. | pmid:6194801 |
| Wientroub S et al. | Changes in tissue concentration of prostaglandins during endochondral bone differentiation. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6582850 |
| Salmon JA et al. | The effects of BW755C and other anti-inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally-induced acute inflammation. | 1983 | J. Pharm. Pharmacol. | pmid:6141244 |
| Nerlich M et al. | Effect of thermal injury on endotoxin-induced lung injury. | 1983 | Surgery | pmid:6337423 |
| Harlan J et al. | Selective inhibition of thromboxane synthesis during experimental endotoxemia in the goat: effects on pulmonary haemodynamics and lung lymph flow. | 1983 | Br J Clin Pharmacol | pmid:6337602 |
| Ball HA et al. | Effect of dazoxiben, a specific inhibitor of thromboxane synthetase, on acute pulmonary responses to E. coli endotoxin in anaesthetized cats. | 1983 | Br J Clin Pharmacol | pmid:6337603 |
| Dodd NJ et al. | Use of a thromboxane synthetase inhibitor, dazoxiben, during haemodialysis. | 1983 | Br J Clin Pharmacol | pmid:6337605 |
| Ylikorkala O et al. | Maternal prostacyclin, thromboxane, and placental blood flow. | 1983 | Am. J. Obstet. Gynecol. | pmid:6338724 |
| Boughton-Smith NK et al. | Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosa. | 1983 | Gut | pmid:6416934 |
| Bromberg Y and Pick E | Unsaturated fatty acids as second messengers of superoxide generation by macrophages. | 1983 | Cell. Immunol. | pmid:6307532 |
| Vlasses PH et al. | Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients. | 1983 | Prostaglandins Leukot Med | pmid:6308685 |
| Huval WV et al. | Thromboxane mediation of cardiovascular dysfunction following aspiration. | 1983 | Surgery | pmid:6308843 |
| Hartung HP | Acetyl glyceryl ether phosphorylcholine (platelet-activating factor) mediates heightened metabolic activity in macrophages. Studies on PGE, TXB2 and O2- production, spreading, and the influence of calmodulin-inhibitor W-7. | 1983 | FEBS Lett. | pmid:6309563 |
| Kaliman J et al. | [Venous prostacycline synthesis and plasma thromboxane B2 after low-dose aspirin]. | 1983 | Wien. Klin. Wochenschr. | pmid:6359724 |
| Ylikorkala O et al. | Prostacyclin and thromboxane in ovarian cancer: effect of cytostatics and prostaglandin synthesis inhibitors. | 1983 | Gynecol. Oncol. | pmid:6360817 |
| Tada M et al. | [Biochemistry of coronary artery disease--prostaglandins]. | 1983 | Rinsho Byori | pmid:6361336 |
| Hardisty RM et al. | A new congenital defect of platelet secretion: impaired responsiveness of the platelets to cytoplasmic free calcium. | 1983 | Br. J. Haematol. | pmid:6830700 |
| Jørgensen KA et al. | The survival of pig to rabbit renal xenografts during inhibition of thromboxane synthesis. | 1983 | Thromb. Res. | pmid:6364449 |
| Feddersen CO et al. | Leukotriene E4 causes pulmonary vasoconstriction, not inhibited by meclofenamate. | 1983 | Prostaglandins | pmid:6098932 |
| Mandrovnaia NV et al. | [Age-related changes in prostacyclin and thromboxane B2 biosynthesis under normal conditions and in arterial hypertension]. | 1983 | Kardiologiia | pmid:6366325 |
| Foegh M et al. | Prostacyclin and thromboxane release from human peritoneal macrophages. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221630 |
| Sinzinger H and Firbas W | [Cells of the vascular wall synthesize thromboxane]. | 1983 | Wien. Klin. Wochenschr. | pmid:6369802 |
| Westwick J et al. | Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221642 |
| Schumacher WA and Lucchesi BR | Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity. | 1983 | J. Pharmacol. Exp. Ther. | pmid:6418881 |
| Sakamoto T | [Studies on platelet function in toxemia of pregnancy]. | 1983 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:6223964 |
| Mehta P et al. | Inhibitory effects of diltiazem on platelet activation caused by ionophore A23187 plus ADP or epinephrine in subthreshold concentrations. | 1983 | J. Lab. Clin. Med. | pmid:6411841 |
| Winchester JF et al. | Early indicators of renal allograft rejection. | 1983 | Kidney Int. Suppl. | pmid:6224041 |
| D'Angelo A et al. | Effect of des-amino-D-arginine vasopressin (DDAVP) on plasma levels of platelet and endothelial cell release products. | 1983 | Thromb. Haemost. | pmid:6687766 |
| Westwick J et al. | Platelet activation during steady state sickle cell disease. | 1983 | J Med | pmid:6224876 |
| Ku EC et al. | Characterization of imidazo[1,5-a]pyridine-5-hexanoic acid (CGS 13080) as a selective thromboxane synthetase inhibitor using in vitro and in vivo biochemical models. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6687803 |
| Anderegg K et al. | Effects of a pyridine derivative thromboxane synthetase inhibitor and its inactive isomer in endotoxic shock in the rat. | 1983 | Br. J. Pharmacol. | pmid:6687819 |
| Ellsworth ML et al. | Pulmonary prostacyclin production with increased flow and sympathetic stimulation. | 1983 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6415017 |
| Todd MH et al. | The involvement of prostaglandins and thromboxanes in the response to pulmonary embolism in anaesthetized rabbits and isolated perfused lungs. | 1983 | Thromb. Res. | pmid:6687961 |
| Halushka PV et al. | Studies on the beneficial effects of aspirin in endotoxic shock. Relationship to inhibition of arachidonic acid metabolism. | 1983 | Am. J. Med. | pmid:6687979 |
| Tsukatani E | Etiology of EPH-gestosis from the viewpoint of dynamics of vasoactive prostanoid, lipid peroxides and vitamin E. | 1983 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:6688085 |
| Fischer S et al. | In vivo and in vitro effects of nafazatrom (Bay g 6575), an antithrombotic compound, on arachidonic acid metabolism in platelets and vascular tissue. | 1983 | Biochem. Pharmacol. | pmid:6688182 |
| Bailey IA et al. | Effects of vascular trauma and transient myocardial ischaemia on coronary venous prostaglandin levels in the dog. | 1983 | Cardiovasc. Res. | pmid:6688202 |
| Srivastava KC and Awasthi KK | Separation and quantitative determination of radiolabeled prostaglandins, thromboxanes, 6-keto-prostaglandin F1 alpha and other arachidonic acid metabolites produced in biological material. | 1983 | J. Chromatogr. | pmid:6688256 |
| Wilson L and Huang LS | Effects of the fetal-placental unit on uterine prostaglandin levels at term in the pregnant rat. | 1983 | Prostaglandins | pmid:6688474 |
| Saldeen P and Saldeen T | 6-keto-prostaglandin F1 alpha/thromboxane B2 ratio in vascular and lung tissue. | 1983 | Thromb. Res. | pmid:6688484 |
| Cortellaro M et al. | Transcoronary platelet thromboxane A2 formation without platelet trapping in patients with coronary stenosis-effect of sulphinpyrazone treatment. | 1983 | Thromb. Haemost. | pmid:6665767 |
| De Caterina R et al. | Antiplatelet effects of isosorbide dinitrate in man. | 1983 | Z Kardiol | pmid:6666233 |
| Smith EF et al. | RCS from human platelets: is it only thromboxane? | 1983 | Eur. J. Pharmacol. | pmid:6667711 |
| Sakanishi N et al. | [Effect of reduced glutathione on endotoxin shock]. | 1983 | Masui | pmid:6668649 |
| Moonen P et al. | An improved method for separation of thromboxane B2 by reversed phase liquid chromatography. | 1983 | Prostaglandins | pmid:6669711 |
| Karmali RA et al. | Prostaglandins in breast cancer: relationship to disease stage and hormone status. | 1983 | Br. J. Cancer | pmid:6416285 |
| Reuben SR et al. | Effects of dazoxiben on exercise performance in chronic stable angina. | 1983 | Br J Clin Pharmacol | pmid:6402000 |
| Güllner HG et al. | Renal thromboxane excretion in Brattleboro rats with hereditary hypothalamic diabetes insipidus. Effect of vasopressin treatment. | 1983 | Prostaglandins Leukot Med | pmid:6580653 |
| Rojas J et al. | Effects of cyclooxygenase inhibition on the response to group B streptococcal toxin in sheep. | 1983 | Pediatr. Res. | pmid:6402752 |
| Sakanishi N et al. | Thromboxane A2 and hemodynamic-biochemical parameters in canine endotoxin shock. | 1983 | Bull. Tokyo Med. Dent. Univ. | pmid:6580966 |
| Förster W and Pönicke K | Influence of sympathomimetic drugs (1-phenyl-2-amino-ethan-1-ol derivatives) on the biosynthesis of prostaglandins and thromboxane B2. | 1983 | Br. J. Pharmacol. | pmid:6403094 |
| Orlandi M et al. | Normal plasma thromboxane B2 (TXB2) and 6-keto-PGF1 alpha levels in childhood diabetes. | 1983 | Prostaglandins Leukot Med | pmid:6583712 |
| Männistö J and Uotila P | Cigarette smoke ventilation decreases thromboxane B2 metabolism in isolated rat lungs. | 1983 | Prostaglandins Leukot Med | pmid:6583713 |
| Nenci GG et al. | Platelet malondialdehyde production kinetics after cyclooxygenase block. A study performed with a modified high sensitivity assay. | 1983 | Haemostasis | pmid:6404715 |
| Sharon P et al. | Prostanoid synthesis by cultured gastric and duodenal mucosa: Possible role in the pathogenesis of duodenal ulcer. | 1983 | Scand. J. Gastroenterol. | pmid:6584967 |
| Lewy RI | Role of thromboxanes in vasotonic versus vaso-occlusive angina. | 1983 | Arch Mal Coeur Vaiss | pmid:6407435 |
| Carr BR et al. | Prostaglandin secretion by the neocortex and fetal zones of the human fetal adrenal gland. | 1983 | J. Clin. Endocrinol. Metab. | pmid:6313732 |