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A phase II study of the 5-lipoxygenase inhibitor, CV6504, in advanced pancreatic cancer: correlation of clinical data with pharmacokinetic and pharmacodynamic endpoints. |
2000 |
Ann. Oncol. |
pmid:11061613
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Ciabattoni G et al. |
In vivo lipid peroxidation and platelet activation in cystic fibrosis. |
2000 |
Am. J. Respir. Crit. Care Med. |
pmid:11029317
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Wang W et al. |
Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. |
2000 |
Acta Pharmacol. Sin. |
pmid:11501172
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Tanus-Santos JE et al. |
The hemodynamic effects of endothelin receptor antagonism during a venous air infusion in dogs. |
2000 |
Anesth. Analg. |
pmid:10624986
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Boatman RJ et al. |
Covalent protein adducts of hydroquinone in tissues from rats: quantitation of sulfhydryl-bound forms following single gavage or intraperitoneal administration or repetitive gavage administration. |
2000 |
Chem. Res. Toxicol. |
pmid:10995259
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Heng W et al. |
[The role of platelet activation in the pathogenesis of asthma]. |
2000 |
Zhonghua Jie He He Hu Xi Za Zhi |
pmid:11778515
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Jacobi KE et al. |
Determination of eicosanoid and cytokine production in salvaged blood, stored red blood cell concentrates, and whole blood. |
2000 |
J Clin Anesth |
pmid:10818321
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Tanus-Santos JE et al. |
Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. |
2000 |
Eur. J. Pharmacol. |
pmid:10822051
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Turpeinen AM et al. |
Similar responses in hemostatic factors after consumption of wholemeal rye bread and low-fiber wheat bread. |
2000 |
Eur J Clin Nutr |
pmid:10822290
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Romano M et al. |
Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide. |
2000 |
J. Investig. Med. |
pmid:10822898
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Sheu JR et al. |
Mechanisms involved in the antiplatelet activity of Staphylococcus aureus lipoteichoic acid in human platelets. |
2000 |
Thromb. Haemost. |
pmid:10823277
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Zhou L et al. |
[The effect of plasma from women with preeclampsia on endothelial cells activators in vitro]. |
2000 |
Zhonghua Fu Chan Ke Za Zhi |
pmid:11776183
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Nosál' R et al. |
Chloroquine: a multipotent inhibitor of human platelets in vitro. |
2000 |
Thromb. Res. |
pmid:10828481
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Homoncik M et al. |
Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100. |
2000 |
Thromb. Haemost. |
pmid:10739392
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Schweizer A et al. |
Aprotinin does not impair renal haemodynamics and function after cardiac surgery. |
2000 |
Br J Anaesth |
pmid:10740541
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Agnoli GC et al. |
Renal synthesis of prostacyclin and thromboxane in healthy women: differential effects of a short-term saline loading. |
2000 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:10780876
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Wakitani K et al. |
JTE-522 selectively inhibits cyclooxygenase-2-derived prostaglandin production in inflammatory tissues. |
2000 |
Inflamm. Res. |
pmid:10807499
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Rilantono LI et al. |
Dietary antioxidative potential in arteries. |
2000 |
Clin. Hemorheol. Microcirc. |
pmid:11321428
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Liao CH et al. |
Antiplatelet effect of marchantinquinone, isolated from Reboulia hemisphaerica, in rabbit washed platelets. |
2000 |
J. Pharm. Pharmacol. |
pmid:10757426
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Prieto MA et al. |
Influence of triflusal on platelet activation after coronary artery bypass graft. |
2000 |
Blood Coagul. Fibrinolysis |
pmid:10759013
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Heller A et al. |
The complement regulators C1 inhibitor and soluble complement receptor 1 attenuate acute lung injury in rabbits. |
2000 |
Shock |
pmid:10774617
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Sane S et al. |
Eicosapentaenoic acid reduces pulmonary edema in endotoxemic rats. |
2000 |
J. Surg. Res. |
pmid:10945939
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Semenov AV et al. |
[Soluble P-selectin - a marker of platelet activation and vessel wall injury: increase of soluble P-selectin in plasma of patients with myocardial infarction, massive atherosclerosis and primary pulmonary hypertension]. |
2000 |
Ter. Arkh. |
pmid:10833791
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Jacobs C et al. |
1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase. |
2000 |
J. Med. Chem. |
pmid:10794700
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Nenci GG and Paliani U |
[Diabetes, coagulation and vascular events]. |
2000 |
Recenti Prog Med |
pmid:10748654
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Kasahara M et al. |
Effect of FK3311 on ischemia-reperfusion injury in canine pulmonary models. |
2000 |
Transplant. Proc. |
pmid:11120230
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De Jong A et al. |
Antiphospholipid antibodies and platelets. |
2000 |
Curr Rheumatol Rep |
pmid:11123065
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Buccellati C et al. |
Tramadol anti-inflammatory activity is not related to a direct inhibitory action on prostaglandin endoperoxide synthases. |
2000 |
Eur J Pain |
pmid:11124014
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Basu S et al. |
Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity. |
2000 |
Clin. Sci. |
pmid:11099394
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Filipov NM et al. |
Anti-inflammatory effects of ergotamine in steers. |
2000 |
Proc. Soc. Exp. Biol. Med. |
pmid:11044256
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Delemarre FM et al. |
Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction. |
2000 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:11049696
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Kawasaki K et al. |
Inhibition of 12(S)-hydroxyeicosatetraenoic acid (12-HETE) production suppressed the intimal hyperplasia caused by poor-runoff conditions in the rabbit autologous vein grafts. |
2000 |
J. Cardiovasc. Pharmacol. |
pmid:11065214
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Vazquez-Cruz B et al. |
Increased renal vasoconstriction and gene expression of cyclooxygenase-1 in renovascular hypertension. |
2000 |
J. Cardiovasc. Pharmacol. |
pmid:11065217
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Greenberg HE et al. |
A new cyclooxygenase-2 inhibitor, rofecoxib (VIOXX), did not alter the antiplatelet effects of low-dose aspirin in healthy volunteers. |
2000 |
J Clin Pharmacol |
pmid:11185674
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Siler-Khodr TM et al. |
Effect of ethanol on thromboxane and prostacyclin production in the human placenta. |
2000 |
Alcohol |
pmid:10963940
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Laguna MS et al. |
[Thromboxane B2 and platelet derived growth factor in essential thrombocythemia treated with anagrelide]. |
2000 |
Medicina (B Aires) |
pmid:11188949
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Matz RL et al. |
Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids. |
2000 |
Br. J. Pharmacol. |
pmid:10991924
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Tanaka H et al. |
Effects of milrinone on platelet aggregation in swine with pulmonary hypertension. |
2000 |
J Crit Care |
pmid:11011824
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Coppola A et al. |
Homocysteine, coagulation, platelet function, and thrombosis. |
2000 |
Semin. Thromb. Hemost. |
pmid:11011842
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Kim WG et al. |
Is avoidance of air contact necessary for the in vitro evaluation of thrombogenicity in mechanical circulatory assist devices? |
2000 |
Artif Organs |
pmid:11012543
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Kim WG et al. |
Vasoconstrictive eicosanoid responses to extracorporeal circulation with or without an oxygenator in fetal lambs. |
2000 |
Int J Artif Organs |
pmid:10941636
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Porta C et al. |
Amifostine, a reactive oxigen species scavenger with radiation- and chemo-protective properties, inhibits in vitro platelet activation induced by ADP, collagen or PAF. |
2000 |
Haematologica |
pmid:10942928
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Wang JS et al. |
Effect of strenuous arm exercise on oxidized-LDL-potentiated platelet activation in individuals with spinal cord injury. |
2000 |
Thromb. Haemost. |
pmid:10928481
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Krysztopik RJ et al. |
Lazaroid and pentoxifylline suppress sepsis-induced increases in renal vascular resistance via altered arachidonic acid metabolism. |
2000 |
J. Surg. Res. |
pmid:10945946
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Stanke-Labesque F et al. |
Angiotensin II-induced contractions in human internal mammary artery: effects of cyclooxygenase and lipoxygenase inhibition. |
2000 |
Cardiovasc. Res. |
pmid:10946074
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Thorwest M et al. |
Dietary fish oil reduces microvascular thrombosis in a porcine experimental model. |
2000 |
Thromb. Res. |
pmid:10946095
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McCann ME et al. |
Effect of intravenous infusion of omega-3 and omega-6 lipid emulsions on equine monocyte fatty acid composition and inflammatory mediator production in vitro. |
2000 |
Shock |
pmid:10947170
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Kamata K et al. |
Altered endothelium-dependent and -independent hyperpolarization and endothelium-dependent relaxation in carotid arteries isolated from streptozotocin-induced diabetic rats. |
2000 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:10935533
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Li JB et al. |
[A further research on physiopathological basis of "Liver Yang Forming Wind Syndrome"]. |
2000 |
Hunan Yi Ke Da Xue Xue Bao |
pmid:12205996
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Ohata T et al. |
Role of nitric oxide in a temperature dependent regulation of systemic vascular resistance in cardiopulmonary bypass. |
2000 |
Eur J Cardiothorac Surg |
pmid:10973545
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Miao X et al. |
[Effect of yinchen dandao decoction on plasma fibronectin, biliary thromboxane A2 and prostaglandin I2 in human and animal suffering from acute cholangitis]. |
2000 |
Zhongguo Zhong Xi Yi Jie He Za Zhi |
pmid:11938860
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Momi S et al. |
Involvement of platelets in experimental mouse trypanosomiasis: evidence of mouse platelet cytotoxicity against Trypanosoma equiperdum. |
2000 |
Exp. Parasitol. |
pmid:10910715
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Moon CH et al. |
Mechanism for antiplatelet effect of onion: AA release inhibition, thromboxane A(2)synthase inhibition and TXA(2)/PGH(2)receptor blockade. |
2000 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:10883058
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Lasserre B et al. |
Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit. |
2000 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:10883059
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Arakida Y et al. |
Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs. |
2000 |
Eur. J. Pharmacol. |
pmid:10969159
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Bereczki C et al. |
The roles of platelet function, thromboxane, blood lipids and nitric oxide in hypertension of children and adolescents. |
2000 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:10883060
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Carty E et al. |
Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. |
2000 |
Aliment. Pharmacol. Ther. |
pmid:10848666
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Dschietzig T et al. |
Stimulation of pulmonary big endothelin-1 and endothelin-1 by antithrombin III: a rationale for combined application of antithrombin III and endothelin antagonists in sepsis-related acute respiratory distress syndrome? |
2000 |
Crit. Care Med. |
pmid:10921577
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Muscará MN et al. |
Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats. |
2000 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:10924050
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Mizugaki M |
[Microdetermination of eicosanoids using mass spectrometry]. |
2000 |
Nippon Yakurigaku Zasshi |
pmid:10876809
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Depré M et al. |
Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans. |
2000 |
Eur. J. Clin. Pharmacol. |
pmid:10877012
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Theriot JA et al. |
Dietary chloride does not correlate with urinary thromboxane in deoxycorticosterone acetate-treated rats. |
2000 |
J. Lab. Clin. Med. |
pmid:10850649
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Kowalska MA et al. |
Stromal cell-derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets. |
2000 |
Blood |
pmid:10891429
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Bailey SR et al. |
Differential activation of platelets from normal and allergic ponies by PAF and ADP. |
2000 |
Inflamm. Res. |
pmid:10893045
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Rao AR and Prabhakar MC |
Screening methods for antiasthmatic agents. |
2000 |
Methods Find Exp Clin Pharmacol |
pmid:10893704
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Cayatte AJ et al. |
The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo E-deficient mice: evidence that eicosanoids other than thromboxane contribute to atherosclerosis. |
2000 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:10894809
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Pärsson HN et al. |
Maintaining carotid flow by shunting during carotid endarterectomy diminishes the inflammatory response mediating ischaemic brain injury. |
2000 |
Eur J Vasc Endovasc Surg |
pmid:10727360
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Armstrong RA et al. |
No effect of dietary trans isomers of alpha-linolenic acid on platelet aggregation and haemostatic factors in european healthy men. The TRANSLinE study. |
2000 |
Thromb. Res. |
pmid:11108899
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Okada S et al. |
Perfusion of the hypothalamic paraventricular nucleus with N-methyl-D-aspartate produces thromboxane A2 and centrally activates adrenomedullary outflow in rats. |
2000 |
Neuroscience |
pmid:10717438
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Zaitsu M et al. |
Ulinastatin, an elastase inhibitor, inhibits the increased mRNA expression of prostaglandin H2 synthase-type 2 in Kawasaki disease. |
2000 |
J. Infect. Dis. |
pmid:10720537
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De La Cruz JP et al. |
Effect of DT-TX 30, a combined thromboxane synthase inhibitor and thromboxane receptor antagonist, on retinal vascularity in experimental diabetes mellitus. |
2000 |
Thromb. Res. |
pmid:10680643
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Suzuki N et al. |
Difference in urinary LTE4 and 11-dehydro-TXB2 excretion in asthmatic patients. |
2000 |
Prostaglandins Other Lipid Mediat. |
pmid:11060902
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Giedrojć J et al. |
[Interaction of platelets with monocytes with regard to arachidonic acid metabolites]. |
2000 |
Prz. Lek. |
pmid:11199865
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Ames PR et al. |
Antioxidant susceptibility of pathogenic pathways in subjects with antiphospholipid antibodies: a pilot study. |
2000 |
Lupus |
pmid:11199924
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Wang ZG et al. |
Can endothelial seeding enhance patency and inhibit neointimal hyperplasia? Experimental studies and clinical trial of endothelial seeded venous prostheses. |
2000 |
Int Angiol |
pmid:11201596
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MacKay RJ et al. |
Effect of eltenac in horses with induced endotoxaemia. |
2000 |
Equine Vet J Suppl |
pmid:11202378
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Cryer B et al. |
Effects of cutaneous aspirin on the human stomach and duodenum. |
1999 Sep-Oct |
Proc. Assoc. Am. Physicians |
pmid:10519166
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Stewart KG et al. |
Estrogen decreases prostaglandin H synthase products from endothelial cells. |
1999 Nov-Dec |
J. Soc. Gynecol. Investig. |
pmid:10643586
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Tong H et al. |
Prostaglandin endoperoxide synthase-2 abundance is increased in brain tissues of late-gestation fetal sheep in response to cerebral hypoperfusion. |
1999 May-Jun |
J. Soc. Gynecol. Investig. |
pmid:10376268
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Uriu K et al. |
Effect of acute thromboxane A2 inhibition on the renal hemodynamics in a spontaneously non-insulin-dependent diabetic rat, Otsuka Long-Evans Tokushima Fatty rat. |
1999 Jul-Aug |
J. Diabetes Complicat. |
pmid:10616856
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Pestana M et al. |
Kidney graft-infiltrating cells synthesize significantly higher amounts of prostaglandin E2 pre and during acute rejection. |
1999 Feb-Mar |
Transplant. Proc. |
pmid:10083119
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van den Dorpel MA et al. |
Beneficial effects of conversion from cyclosporine to azathioprine on fibrinolysis in renal transplant recipients. |
1999 Feb-Mar |
Transplant. Proc. |
pmid:10083130
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Tomoeda H |
Effects of leukocyte-depleted warm blood cardioplegia on cardiac and endothelial function. |
1999 |
Kurume Med J |
pmid:10319611
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Arons MM et al. |
Effects of ibuprofen on the physiology and survival of hypothermic sepsis. Ibuprofen in Sepsis Study Group. |
1999 |
Crit. Care Med. |
pmid:10321658
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Titos E et al. |
Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4). |
1999 |
Am. J. Physiol. |
pmid:10564079
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Hu Z et al. |
[Experimental study of influence of yiqi huoxue serial recipes on basement membrane in membranous nephritis in rabbits]. |
1999 |
Zhongguo Zhong Xi Yi Jie He Za Zhi |
pmid:11783306
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Reis F et al. |
The peripheral serotonergic system and platelet aggregation in cyclosporin A-induced hypertensive rats. |
1999 |
Thromb. Res. |
pmid:10605951
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Eldor A et al. |
A chronic hypercoagulable state in patients with beta-thalassaemia major is already present in childhood. |
1999 |
Br. J. Haematol. |
pmid:10606878
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Freedman JE et al. |
Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene. |
1999 |
Circ. Res. |
pmid:10381894
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Cryer B and Feldman M |
Effects of very low dose daily, long-term aspirin therapy on gastric, duodenal, and rectal prostaglandin levels and on mucosal injury in healthy humans. |
1999 |
Gastroenterology |
pmid:10381905
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Kubo K et al. |
A 21-aminosteroid, U-74006F, attenuates endotoxin-induced lung injury in awake sheep. |
1999 |
Respirology |
pmid:10382236
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Shen AY et al. |
Inhibition of 2-P-mercaptophenyl-1,4-naphthoquinone on human platelet function. |
1999 |
Life Sci. |
pmid:10403492
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Barchasz E et al. |
Interleukin-1beta-induced hyperresponsiveness to [Sar9,Met(O2)11]substance P in isolated human bronchi. |
1999 |
Eur. J. Pharmacol. |
pmid:10499376
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Tanus-Santos JE et al. |
Inhaled nitric oxide improves hemodynamics during a venous air infusion (VAI) in dogs. |
1999 |
Intensive Care Med |
pmid:10501756
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Gurbel PA et al. |
Plasma thromboxane and prostacyclin are linear related and increased in patients presenting with acute myocardial infarction. |
1999 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:10477035
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Itasaka H et al. |
The mechanism of hepatic graft protection against reperfusion injury by prostaglandin E1. |
1999 |
Surg. Today |
pmid:10385367
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Maitra SR et al. |
Alterations in hepatic gluconeogenesis, prostanoid, and intracellular calcium during sepsis. |
1999 |
Acad Emerg Med |
pmid:10386675
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McCowan LM et al. |
Administration of low-dose aspirin to mothers with small for gestational age fetuses and abnormal umbilical Doppler studies to increase birthweight: a randomised double-blind controlled trial. |
1999 |
Br J Obstet Gynaecol |
pmid:10428519
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Dickneite G and Leithäuser B |
Influence of antithrombin III on coagulation and inflammation in porcine septic shock. |
1999 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:10364091
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Gust R et al. |
Response to inhaled nitric oxide in acute lung injury depends on distribution of pulmonary blood flow prior to its administration. |
1999 |
Am. J. Respir. Crit. Care Med. |
pmid:9927374
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