Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Endotoxemia D019446 27 associated lipids
Thrombophilia D019851 6 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Venous Thrombosis D020246 11 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Prancan AV et al. L8027 and 1-nonyl-imidazole as non-selective inhibitors of thromboxane synthesis. 1979 Eur. J. Pharmacol. pmid:527664
Makheja AN et al. Effects of onion (Allium cepa) extract on platelet aggregation and thromboxane synthesis. 1979 Prostaglandins Med pmid:552092
Lefer AM et al. Protective effects of a novel thromboxane analog in lethal traumatic shock. 1979 Prostaglandins Med pmid:552102
Kanzaki Y et al. Thromboxane as possible trigger of liver regeneration. 1979 Cell Mol Biol Incl Cyto Enzymol pmid:535003
Lewy RI et al. Comparison of plasma concentrations of thromboxane B2 in Prinzmetal's variant angina and classical angina pectoris. 1979 Clin Cardiol pmid:544110
Patrono C et al. Inhibition of platelet cyclooxygenase by aspirin-like drugs: methods for in vitro and ex vivo assessment. 1979 Agents Actions Suppl. pmid:115255
Wong PY and Cheung WY Calmodulin stimulates human platelet phospholipase A2. 1979 Biochem. Biophys. Res. Commun. pmid:116656
Okuma M and Uchino H Altered arachidonate metabolism by platelets in patients with myeloproliferative disorders. 1979 Blood pmid:116695
Best LC et al. Evidence that extracellular calcium ions inhibit thromboxane B2 biosynthesis by human platelets. 1979 Biochem. Biophys. Res. Commun. pmid:117802
Oelz O [The arachidonic acid metabolites (prostaglandins, thromboxanes, prostacyclin, leucotrienes):basics and clinical implications (author's transl)]. 1979 Ther Umsch pmid:119331
Gorman RR et al. Independence of the cyclic AMP-lowering activity of thromboxane A2 from the platelet release reaction. 1979 Biochim. Biophys. Acta pmid:216409
Boura AL and Murphy RD Thromboxane B2 inhibits prostaglandin E2 inactivation by the rat isolated perfused lung. 1978 Jul-Aug Clin. Exp. Pharmacol. Physiol. pmid:699382
Tai HH and Yuan B Development of radioimmunoassay for thromboxane B2. 1978 Anal. Biochem. pmid:567443
Murota S and Morita I Effect of prostaglandin I2 and related compounds on vascular permeability response in granuloma tissues. 1978 Prostaglandins pmid:635221
Powell WS and Solomon S Biosynthesis of prostaglandins and thromboxane B2 by fetal lung homogenates. 1978 Prostaglandins pmid:635224
Tai HH et al. Transformation of arachidonate into 6-oxoprostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 by sheep lung microsomal fraction. 1978 Biochem. J. pmid:637853
Murota SI et al. Transformation of arachidonic acid into thromboxane B2 by the homogenates of activated macrophages. 1978 Biochim. Biophys. Acta pmid:638172
Mallen DN et al. Structural verification of 15-oxo-13,14-dihydrothromboxane B2. 1978 Biomed. Mass Spectrom. pmid:678616
Mitchell MD et al. Thromboxane B2 and human parturition: concentrations in the plasma and production in vitro. 1978 J. Endocrinol. pmid:712300
Yoshimoto T et al. Selective inhibition of prostaglandin endoperoxide thromboxane isomerase by 1-carboxyalkylimidazoles. 1978 Prostaglandins pmid:725083