Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Aortic Arch Syndromes D001015 2 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Edema, Cardiac D004489 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Yang Deficiency D016711 3 associated lipids
Bluetongue D001819 1 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Foot Rot D005535 1 associated lipids
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Li G et al. Cardiac ischemic preconditioning improves lung preservation in valve replacement operations. 2001 Ann. Thorac. Surg. pmid:11235719
Agnoli GC et al. Volume-induced natriuresis in healthy women: renal metabolism of prostacyclin and thromboxane, and physiological role of prostanoids. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11237476
Liu ZQ et al. [Effect of Astragalus injection on platelet function and plasma endothelin in patients with early stage diabetic nephropathy]. 2001 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:12577356
Qureshi AA et al. Novel tocotrienols of rice bran suppress cholesterogenesis in hereditary hypercholesterolemic swine. 2001 J. Nutr. pmid:11160537
Lin CL et al. [Therapeutic mechanism of combination therapy of ligustrazine and nitrendipine in treating patients with chronic obstructive pulmonary disease]. 2001 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:12577373
Bölke E et al. Changes of gut barrier function during anesthesia and cardiac surgery. 2001 Angiology pmid:11515987
Riendeau D et al. Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2. 2001 J. Pharmacol. Exp. Ther. pmid:11160644
Iuliano L et al. Angioplasty increases coronary sinus F2-isoprostane formation: evidence for in vivo oxidative stress during PTCA. 2001 J. Am. Coll. Cardiol. pmid:11153776
Valeri CR et al. Anemia-induced increase in the bleeding time: implications for treatment of nonsurgical blood loss. 2001 Transfusion pmid:11493727
Coelho-Filho OR et al. Pravastatin reduces myocardial lesions induced by acute inhibition of nitric oxide biosynthesis in normocholesterolemic rats. 2001 Int. J. Cardiol. pmid:11461744
Wojakowski W and Gmiński J Plasma levels of von willebrand factor, endothelin-1, prostacyclin and thromboxane in children from families with high risk of premature coronary artery disease. 2001 Scand. J. Clin. Lab. Invest. pmid:11465346
Rosón MI et al. Serotonin hypersensitivity in aorta of two kidney-two clip hypertensive rats: calcium contribution and prostanoids-nitric oxide interactions. 2001 Arch. Physiol. Biochem. pmid:11471069
Catella-Lawson F et al. Oral glycoprotein IIb/IIIa antagonism in patients with coronary artery disease. 2001 Am. J. Cardiol. pmid:11472700
Takeyoshi I et al. The effect of a selective cyclooxygenase-2 inhibitor in extended liver resection with ischemia in dogs. 2001 J. Surg. Res. pmid:11516201
Muramatsu H et al. [Correlation between the clinical effects of Seratrodast and the level of 11-dehydrothromboxane B2 in urine/sputum in bronchial asthma patients]. 2001 Arerugi pmid:11517517
Calzada C et al. 12(S)-Hydroperoxy-eicosatetraenoic acid increases arachidonic acid availability in collagen-primed platelets. 2001 J. Lipid Res. pmid:11518767
Fritsma GA et al. Monitoring the antiplatelet action of aspirin. 2001 JAAPA pmid:11523339
Oketani K et al. In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production. 2001 Eur. J. Pharmacol. pmid:11430933
Urquhart P et al. Profile of eicosanoids produced by human saphenous vein endothelial cells and the effect of dietary fatty acids. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11487303
Gao YJ and Lee RM Hydrogen peroxide induces a greater contraction in mesenteric arteries of spontaneously hypertensive rats through thromboxane A(2) production. 2001 Br. J. Pharmacol. pmid:11739239
Domoki F et al. Cyclooxygenase-2 inhibitor NS398 preserves neuronal function after hypoxia/ischemia in piglets. 2001 Neuroreport pmid:11742239
McConnell JP et al. Urinary 11-dehydro-thromboxane B(2) and coagulation activation markers measured within 24 h of human acute ischemic stroke. 2001 Neurosci. Lett. pmid:11684346
Wan Y et al. Effects of cocoa powder and dark chocolate on LDL oxidative susceptibility and prostaglandin concentrations in humans. 2001 Am. J. Clin. Nutr. pmid:11684527
Wang ZY et al. Comparative study of platelet activation markers in diabetes mellitus patients complicated by cerebrovascular disease. 2001 Blood Coagul. Fibrinolysis pmid:11685040
Gloor B et al. Hydrocortisone treatment of early SIRS in acute experimental pancreatitis. 2001 Dig. Dis. Sci. pmid:11680590
Stichtenoth DO et al. Effects of intravenous oxygen on prostacyclin and thromboxane formation in patients with peripheral occlusive arterial disease. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728174
Oketani K et al. Effect of E3040, an inhibitor of 5-lipoxygenase and thromboxane synthase, on rat bowel damage induced by lipopolysaccharide. 2001 Eur. J. Pharmacol. pmid:11557269
Franconi F et al. Effect of gamma-hydroxybutyric acid on human platelet aggregation in vitro. 2001 Thromb. Res. pmid:11369419
Loew D et al. Investigations on the pharmacokinetic properties of Harpagophytum extracts and their effects on eicosanoid biosynthesis in vitro and ex vivo. 2001 Clin. Pharmacol. Ther. pmid:11372004
Hishinuma T et al. Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728171
Yoshinari D et al. Effects of a dual inhibitor of tumor necrosis factor-alpha and interleukin-1 on lipopolysaccharide-induced lung injury in rats: involvement of the p38 mitogen-activated protein kinase pathway. 2001 Crit. Care Med. pmid:11373433
Feldman M et al. Effects of low-dose aspirin on serum C-reactive protein and thromboxane B2 concentrations: a placebo-controlled study using a highly sensitive C-reactive protein assay. 2001 J. Am. Coll. Cardiol. pmid:11419884
Kaaja R et al. Increased thromboxane production in women with a history of venous thromboembolic event: effect of heparins. 2001 Br. J. Haematol. pmid:11552994
Dubé JN et al. Characterization of a partial prostaglandin endoperoxide H synthase-1 deficiency in a patient with a bleeding disorder. 2001 Br. J. Haematol. pmid:11442478
Katoh M et al. Inhibitory effects of TA-993 and its metabolite MB3 on platelet activation induced by collagen and U-46619 in human platelets. 2001 Biol. Pharm. Bull. pmid:11379769
Miyake K et al. Effects of olopatadine hydrochloride on the increase of histamine and peptide-leukotrienes concentrations in nasal lavage fluid following the antigen-antibody reaction in actively sensitized guinea pigs. 2001 Jpn. J. Pharmacol. pmid:11388650
Kurokawa K et al. Circadian characteristics of urinary leukotriene E(4) in healthy subjects and nocturnal asthmatic patients. 2001 Chest pmid:11742908
Spinarová L et al. [Physical training in patients with chornic heart failure: haemodynamics, effects]. 2001 Vnitr Lek pmid:15635849
Tran HS et al. Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock. 2001 Crit. Care Med. pmid:11445706
MalatyalioÄŸlu E et al. Levels of stable metabolites of prostacyclin and thromboxane A2 and their ratio in normotensive and preeclamptic pregnant women during the antepartum and postpartum periods. 2000 May-Jun J Matern Fetal Med pmid:10914626
Parker CR et al. Umbilical cord serum levels of thromboxane B2 in term infants of women who participated in a placebo-controlled trial of low-dose aspirin. 2000 Jul-Aug J Matern Fetal Med pmid:11048830
Ferry DR et al. A phase II study of the 5-lipoxygenase inhibitor, CV6504, in advanced pancreatic cancer: correlation of clinical data with pharmacokinetic and pharmacodynamic endpoints. 2000 Ann. Oncol. pmid:11061613
Ciabattoni G et al. In vivo lipid peroxidation and platelet activation in cystic fibrosis. 2000 Am. J. Respir. Crit. Care Med. pmid:11029317
Wang W et al. Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. 2000 Acta Pharmacol. Sin. pmid:11501172
Tanus-Santos JE et al. The hemodynamic effects of endothelin receptor antagonism during a venous air infusion in dogs. 2000 Anesth. Analg. pmid:10624986
Boatman RJ et al. Covalent protein adducts of hydroquinone in tissues from rats: quantitation of sulfhydryl-bound forms following single gavage or intraperitoneal administration or repetitive gavage administration. 2000 Chem. Res. Toxicol. pmid:10995259
Jacobi KE et al. Determination of eicosanoid and cytokine production in salvaged blood, stored red blood cell concentrates, and whole blood. 2000 J Clin Anesth pmid:10818321
Tanus-Santos JE et al. Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. 2000 Eur. J. Pharmacol. pmid:10822051
Turpeinen AM et al. Similar responses in hemostatic factors after consumption of wholemeal rye bread and low-fiber wheat bread. 2000 Eur J Clin Nutr pmid:10822290
Romano M et al. Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide. 2000 J. Investig. Med. pmid:10822898
Sheu JR et al. Mechanisms involved in the antiplatelet activity of Staphylococcus aureus lipoteichoic acid in human platelets. 2000 Thromb. Haemost. pmid:10823277
Zhou L et al. [The effect of plasma from women with preeclampsia on endothelial cells activators in vitro]. 2000 Zhonghua Fu Chan Ke Za Zhi pmid:11776183
Nosál' R et al. Chloroquine: a multipotent inhibitor of human platelets in vitro. 2000 Thromb. Res. pmid:10828481
Homoncik M et al. Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100. 2000 Thromb. Haemost. pmid:10739392
Schweizer A et al. Aprotinin does not impair renal haemodynamics and function after cardiac surgery. 2000 Br J Anaesth pmid:10740541
Agnoli GC et al. Renal synthesis of prostacyclin and thromboxane in healthy women: differential effects of a short-term saline loading. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780876
Wakitani K et al. JTE-522 selectively inhibits cyclooxygenase-2-derived prostaglandin production in inflammatory tissues. 2000 Inflamm. Res. pmid:10807499
Rilantono LI et al. Dietary antioxidative potential in arteries. 2000 Clin. Hemorheol. Microcirc. pmid:11321428
Liao CH et al. Antiplatelet effect of marchantinquinone, isolated from Reboulia hemisphaerica, in rabbit washed platelets. 2000 J. Pharm. Pharmacol. pmid:10757426
Prieto MA et al. Influence of triflusal on platelet activation after coronary artery bypass graft. 2000 Blood Coagul. Fibrinolysis pmid:10759013
Heller A et al. The complement regulators C1 inhibitor and soluble complement receptor 1 attenuate acute lung injury in rabbits. 2000 Shock pmid:10774617
Semenov AV et al. [Soluble P-selectin - a marker of platelet activation and vessel wall injury: increase of soluble P-selectin in plasma of patients with myocardial infarction, massive atherosclerosis and primary pulmonary hypertension]. 2000 Ter. Arkh. pmid:10833791
Kasahara M et al. Effect of FK3311 on ischemia-reperfusion injury in canine pulmonary models. 2000 Transplant. Proc. pmid:11120230
De Jong A et al. Antiphospholipid antibodies and platelets. 2000 Curr Rheumatol Rep pmid:11123065
Buccellati C et al. Tramadol anti-inflammatory activity is not related to a direct inhibitory action on prostaglandin endoperoxide synthases. 2000 Eur J Pain pmid:11124014
Basu S et al. Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity. 2000 Clin. Sci. pmid:11099394
Filipov NM et al. Anti-inflammatory effects of ergotamine in steers. 2000 Proc. Soc. Exp. Biol. Med. pmid:11044256
Delemarre FM et al. Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11049696
Kawasaki K et al. Inhibition of 12(S)-hydroxyeicosatetraenoic acid (12-HETE) production suppressed the intimal hyperplasia caused by poor-runoff conditions in the rabbit autologous vein grafts. 2000 J. Cardiovasc. Pharmacol. pmid:11065214
Vazquez-Cruz B et al. Increased renal vasoconstriction and gene expression of cyclooxygenase-1 in renovascular hypertension. 2000 J. Cardiovasc. Pharmacol. pmid:11065217
Greenberg HE et al. A new cyclooxygenase-2 inhibitor, rofecoxib (VIOXX), did not alter the antiplatelet effects of low-dose aspirin in healthy volunteers. 2000 J Clin Pharmacol pmid:11185674
Siler-Khodr TM et al. Effect of ethanol on thromboxane and prostacyclin production in the human placenta. 2000 Alcohol pmid:10963940
Laguna MS et al. [Thromboxane B2 and platelet derived growth factor in essential thrombocythemia treated with anagrelide]. 2000 Medicina (B Aires) pmid:11188949
Matz RL et al. Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids. 2000 Br. J. Pharmacol. pmid:10991924
Tanaka H et al. Effects of milrinone on platelet aggregation in swine with pulmonary hypertension. 2000 J Crit Care pmid:11011824
Coppola A et al. Homocysteine, coagulation, platelet function, and thrombosis. 2000 Semin. Thromb. Hemost. pmid:11011842
Kim WG et al. Is avoidance of air contact necessary for the in vitro evaluation of thrombogenicity in mechanical circulatory assist devices? 2000 Artif Organs pmid:11012543
Kim WG et al. Vasoconstrictive eicosanoid responses to extracorporeal circulation with or without an oxygenator in fetal lambs. 2000 Int J Artif Organs pmid:10941636
Porta C et al. Amifostine, a reactive oxigen species scavenger with radiation- and chemo-protective properties, inhibits in vitro platelet activation induced by ADP, collagen or PAF. 2000 Haematologica pmid:10942928
Krysztopik RJ et al. Lazaroid and pentoxifylline suppress sepsis-induced increases in renal vascular resistance via altered arachidonic acid metabolism. 2000 J. Surg. Res. pmid:10945946
Stanke-Labesque F et al. Angiotensin II-induced contractions in human internal mammary artery: effects of cyclooxygenase and lipoxygenase inhibition. 2000 Cardiovasc. Res. pmid:10946074
Miao X et al. [Effect of yinchen dandao decoction on plasma fibronectin, biliary thromboxane A2 and prostaglandin I2 in human and animal suffering from acute cholangitis]. 2000 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11938860
Momi S et al. Involvement of platelets in experimental mouse trypanosomiasis: evidence of mouse platelet cytotoxicity against Trypanosoma equiperdum. 2000 Exp. Parasitol. pmid:10910715
Moon CH et al. Mechanism for antiplatelet effect of onion: AA release inhibition, thromboxane A(2)synthase inhibition and TXA(2)/PGH(2)receptor blockade. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10883058
Lasserre B et al. Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10883059
Bereczki C et al. The roles of platelet function, thromboxane, blood lipids and nitric oxide in hypertension of children and adolescents. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10883060
Carty E et al. Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. 2000 Aliment. Pharmacol. Ther. pmid:10848666
Dschietzig T et al. Stimulation of pulmonary big endothelin-1 and endothelin-1 by antithrombin III: a rationale for combined application of antithrombin III and endothelin antagonists in sepsis-related acute respiratory distress syndrome? 2000 Crit. Care Med. pmid:10921577
Muscará MN et al. Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10924050
Mizugaki M [Microdetermination of eicosanoids using mass spectrometry]. 2000 Nippon Yakurigaku Zasshi pmid:10876809
Depré M et al. Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans. 2000 Eur. J. Clin. Pharmacol. pmid:10877012
Theriot JA et al. Dietary chloride does not correlate with urinary thromboxane in deoxycorticosterone acetate-treated rats. 2000 J. Lab. Clin. Med. pmid:10850649
Kowalska MA et al. Stromal cell-derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets. 2000 Blood pmid:10891429
Bailey SR et al. Differential activation of platelets from normal and allergic ponies by PAF and ADP. 2000 Inflamm. Res. pmid:10893045
Rao AR and Prabhakar MC Screening methods for antiasthmatic agents. 2000 Methods Find Exp Clin Pharmacol pmid:10893704
Cayatte AJ et al. The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo E-deficient mice: evidence that eicosanoids other than thromboxane contribute to atherosclerosis. 2000 Arterioscler. Thromb. Vasc. Biol. pmid:10894809
Pärsson HN et al. Maintaining carotid flow by shunting during carotid endarterectomy diminishes the inflammatory response mediating ischaemic brain injury. 2000 Eur J Vasc Endovasc Surg pmid:10727360
Armstrong RA et al. No effect of dietary trans isomers of alpha-linolenic acid on platelet aggregation and haemostatic factors in european healthy men. The TRANSLinE study. 2000 Thromb. Res. pmid:11108899
Suzuki N et al. Difference in urinary LTE4 and 11-dehydro-TXB2 excretion in asthmatic patients. 2000 Prostaglandins Other Lipid Mediat. pmid:11060902
Giedrojć J et al. [Interaction of platelets with monocytes with regard to arachidonic acid metabolites]. 2000 Prz. Lek. pmid:11199865