Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Aortic Arch Syndromes D001015 2 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Edema, Cardiac D004489 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Yang Deficiency D016711 3 associated lipids
Bluetongue D001819 1 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Foot Rot D005535 1 associated lipids
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Mizutani T et al. Effects of a thromboxane receptor antagonist (NT-126) and a thromboxane synthase inhibitor (OKY-O46) on protamine-induced circulatory changes in dogs. 2000 J. Cardiothorac. Vasc. Anesth. pmid:11139110
Alric L et al. Reactive oxygen intermediates and eicosanoid production by kupffer cells and infiltrated macrophages in acute and chronic liver injury induced in rats by CCl4. 2000 Inflamm. Res. pmid:11211921
Demasi M et al. Assay of cyclooxygenase-1 and 2 in human monocytes. 2000 Inflamm. Res. pmid:11211927
Yang G et al. Effects of prostaglandins and leukotrienes on hypoxic pulmonary vasoconstriction in rats. 2000 J. Tongji Med. Univ. pmid:11215045
Kitano T et al. Unwashed shed blood infusion causes deterioration in right ventricular function after coronary artery surgery. 2000 Anaesth Intensive Care pmid:11153289
Zeng W and Zhang M [Relationship between the alteration of 6-keto-PGF1 alpha and TXB2 in cervical mucus of patients with threatened preterm labor and the efficacy of magnesium sulfate treatment]. 2000 Hua Xi Yi Ke Da Xue Xue Bao pmid:12501615
Khan HH et al. Plasma CPU-86017 concentrations regarding suppression of ouabain-induced cardiac arrhythmias and decrease of heart rate in guinea pigs. 2000 Acta Pharmacol. Sin. pmid:11501061
Wang W et al. Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. 2000 Acta Pharmacol. Sin. pmid:11501172
Praticò D et al. Endogenous biosynthesis of thromboxane and prostacyclin in 2 distinct murine models of atherosclerosis. 2000 Blood pmid:11090066
Leese PT et al. Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: a randomized, controlled trial. 2000 J Clin Pharmacol pmid:10664917
Montini G et al. Renal glomerular response to the inhibition of prostaglandin E2 synthesis and protein loading after the relief of unilateral ureteropelvic junction obstruction. 2000 J. Urol. pmid:10647684
Chou TC et al. Mechanism of inhibition of platelet aggregation by HCL-31D. 2000 Eur. J. Pharmacol. pmid:10650152
Xu L et al. [Clinical and experimental study on effect of Chanbei Kechuanping in treating bronchial asthma]. 2000 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11789166
Han G et al. [Inhibitory effect of panicoin on platelet activation and its mechanism]. 2000 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11789213
Belton O et al. Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. 2000 Circulation pmid:10952950
Jacobi KE et al. Determination of eicosanoid and cytokine production in salvaged blood, stored red blood cell concentrates, and whole blood. 2000 J Clin Anesth pmid:10818321
Tanus-Santos JE et al. Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. 2000 Eur. J. Pharmacol. pmid:10822051
Turpeinen AM et al. Similar responses in hemostatic factors after consumption of wholemeal rye bread and low-fiber wheat bread. 2000 Eur J Clin Nutr pmid:10822290
Romano M et al. Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide. 2000 J. Investig. Med. pmid:10822898
Zhou L et al. [The effect of plasma from women with preeclampsia on endothelial cells activators in vitro]. 2000 Zhonghua Fu Chan Ke Za Zhi pmid:11776183
Patrignani P et al. Effects of vitamin E supplementation on F(2)-isoprostane and thromboxane biosynthesis in healthy cigarette smokers. 2000 Circulation pmid:10920066
Thomson M et al. Thromboxane-B(2) levels in serum of rabbits receiving a single intravenous dose of aqueous extract of garlic and onion. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11049697
Qu X et al. Selenium deficiency-induced alterations in the vascular system of the rat. 2000 Biol Trace Elem Res pmid:11051602
Rahman K and Billington D Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans. 2000 J. Nutr. pmid:11053504
De Somer F et al. Phosphorylcholine coating of extracorporeal circuits provides natural protection against blood activation by the material surface. 2000 Eur J Cardiothorac Surg pmid:11053824
Wang LL et al. Effects of MN-9202 on platelet aggregation, 5-HT release, TXB2 synthesis, and calcium mobilization in rabbit platelets in vitro. 2000 Acta Pharmacol. Sin. pmid:11360670
Naito Y et al. Increase in blood pressure with enhanced Na+, K+ -ATPase activity in stroke-prone spontaneously hypertensive rats after 4-weeks intake of rapeseed oil as the sole dietary fat. 2000 Pharmacol. Toxicol. pmid:11068856
Van Hecken A et al. Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers. 2000 J Clin Pharmacol pmid:11028250
Boyle JR et al. Endovascular AAA repair attenuates the inflammatory and renal responses associated with conventional surgery. 2000 J. Endovasc. Ther. pmid:11032254
De La Cruz JP et al. Antithrombotic potential of olive oil administration in rabbits with elevated cholesterol. 2000 Thromb. Res. pmid:11113274
Darlametsos IE et al. Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: roles of the thromboxane and endothelin systems. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11090252
Cruz MA et al. Vascular reactivity to angiotensin II and eicosanoid production in the human placenta from term and preterm pregnancy. 2000 Gynecol. Obstet. Invest. pmid:11093047
Kasahara M et al. Effect of FK3311 on ischemia-reperfusion injury in canine pulmonary models. 2000 Transplant. Proc. pmid:11120230
De Jong A et al. Antiphospholipid antibodies and platelets. 2000 Curr Rheumatol Rep pmid:11123065
Buccellati C et al. Tramadol anti-inflammatory activity is not related to a direct inhibitory action on prostaglandin endoperoxide synthases. 2000 Eur J Pain pmid:11124014
Basu S et al. Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity. 2000 Clin. Sci. pmid:11099394
Filipov NM et al. Anti-inflammatory effects of ergotamine in steers. 2000 Proc. Soc. Exp. Biol. Med. pmid:11044256
Numminen H et al. The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation. 2000 Stroke pmid:10835443
Kawasaki K et al. Inhibition of 12(S)-hydroxyeicosatetraenoic acid (12-HETE) production suppressed the intimal hyperplasia caused by poor-runoff conditions in the rabbit autologous vein grafts. 2000 J. Cardiovasc. Pharmacol. pmid:11065214
Tsikas D et al. Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine. 2000 J Chromatogr A pmid:10941682
Greenberg HE et al. A new cyclooxygenase-2 inhibitor, rofecoxib (VIOXX), did not alter the antiplatelet effects of low-dose aspirin in healthy volunteers. 2000 J Clin Pharmacol pmid:11185674
Laguna MS et al. [Thromboxane B2 and platelet derived growth factor in essential thrombocythemia treated with anagrelide]. 2000 Medicina (B Aires) pmid:11188949
Cracowski JL et al. Human internal mammary artery contraction by isoprostaglandin f(2alpha) type-III [8-iso-prostaglandin F(2alpha)]. 2000 Eur. J. Pharmacol. pmid:10844110
Yuk DY et al. Antithrombotic and antiplatelet activities of 2-chloro-3-[4-(ethylcarboxy)-phenyl]-amino-1,4-naphthoquinone (NQ12), a newly synthesized 1,4-naphthoquinone derivative. 2000 Biochem. Pharmacol. pmid:10974210
Sabha M et al. Transdermal nicotine mimics the smoking-induced endothelial dysfunction. 2000 Clin. Pharmacol. Ther. pmid:10976548
van Haeringen NJ et al. Flurbiprofen and enantiomers in ophthalmic solution tested as inhibitors of prostanoid synthesis in human blood. 2000 J Ocul Pharmacol Ther pmid:10977130
WÅ‚odarczyk Z et al. Effects of pentoxifylline treatment on delayed graft function in cadaveric kidney recipients. 2000 Transplant. Proc. pmid:10995988
Moosig F et al. Opsonization of apoptotic neutrophils by anti-neutrophil cytoplasmic antibodies (ANCA) leads to enhanced uptake by macrophages and increased release of tumour necrosis factor-alpha (TNF-alpha). 2000 Clin. Exp. Immunol. pmid:11122261
de Jong CL et al. Maternal thromboxane and prostacyclin levels in relation to fetal birth weight. 2000 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:11000507
Jacoby RF et al. The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. 2000 Cancer Res. pmid:11016626
Ogura Y et al. Chemoprevention of biliary carcinogenesis in syrian hamsters by the novel carboxamide derivative IS-741 after initiation with N-nitrosobis(2-oxopropyl)amine (BOP). 2000 Carcinogenesis pmid:10910946
Sugimoto KI et al. Delayed hypotensive effect of the thromboxane A2/prostaglandin H2 receptor antagonist S-1452 in spontaneously hypertensive rats. 2000 Clin. Exp. Pharmacol. Physiol. pmid:10901388
Wang Z et al. [Clinical and experimental study on treatment of bronchial asthma with pingchuan oral liquid]. 2000 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11938808
Köfeler HC et al. Effect of cytochrome P-450 inhibitors econazole, bifonazole and clotrimazole on prostanoid formation. 2000 Br. J. Pharmacol. pmid:10903961
Yu K et al. [Clinical observation on treatment of pediatric intractable nephropathy with modified taohong siwu decoction]. 2000 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11938829
Toft G et al. Intravenously and topically applied magnesium in the prevention of arterial thrombosis. 2000 Thromb. Res. pmid:10904104
Shi X et al. [Effects of Salvia miltiorrhiza compound injection on serum endothelin, prostaglandin I2/thromboxane A2 ratio alteration following myocardial ischemia-reperfusion in patients undergoing intracardiac surgery]. 2000 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11938858
Giedrojć J et al. [Investigation of prostaglandins in supernatant of cultured monocytes]. 2000 Prz. Lek. pmid:10907365
Miao X et al. [Effect of yinchen dandao decoction on plasma fibronectin, biliary thromboxane A2 and prostaglandin I2 in human and animal suffering from acute cholangitis]. 2000 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11938860
Momi S et al. Involvement of platelets in experimental mouse trypanosomiasis: evidence of mouse platelet cytotoxicity against Trypanosoma equiperdum. 2000 Exp. Parasitol. pmid:10910715
Moon CH et al. Mechanism for antiplatelet effect of onion: AA release inhibition, thromboxane A(2)synthase inhibition and TXA(2)/PGH(2)receptor blockade. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10883058
Lasserre B et al. Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10883059
Bereczki C et al. The roles of platelet function, thromboxane, blood lipids and nitric oxide in hypertension of children and adolescents. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10883060
Carty E et al. Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. 2000 Aliment. Pharmacol. Ther. pmid:10848666
Dschietzig T et al. Stimulation of pulmonary big endothelin-1 and endothelin-1 by antithrombin III: a rationale for combined application of antithrombin III and endothelin antagonists in sepsis-related acute respiratory distress syndrome? 2000 Crit. Care Med. pmid:10921577
Nagano K et al. Prostanoids regulate proliferation of vascular smooth muscle cells induced by arginine vasopressin. 2000 Eur. J. Pharmacol. pmid:10686292
Weber AA et al. 40 mg of aspirin are not sufficient to inhibit platelet function under conditions of limited compliance. 2000 Thromb. Res. pmid:10709913
Okumura M et al. Renal production of thromboxane and prostaglandins in a rat model of type 2 diabetes. 2000 Life Sci. pmid:10670825
Wu TM et al. Inhibitory effect of hexapeptide (RGRHGD) on platelet aggregation. 2000 Thromb. Res. pmid:10674405
Jacobi K et al. Plasma levels of eicosanoids after transfusion of intraoperatively salvaged blood. 2000 Vox Sang. pmid:10729809
Tegeder I et al. Effects of selective and unselective cyclooxygenase inhibitors on prostanoid release from various rat organs. 2000 J. Pharmacol. Exp. Ther. pmid:10688636
Rioja I et al. An anti-inflammatory ditriazine inhibiting leukocyte functions and expression of inducible nitric oxide synthase and cyclo-oxygenase-2. 2000 Eur. J. Pharmacol. pmid:10844115
Tran HS et al. The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock. 2000 Shock pmid:10847636
Maccarrone M et al. Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells. 2000 Biochem. Biophys. Res. Commun. pmid:10833416
Gardan B et al. Vasoconstrictor effects of iso-prostaglandin F2alpha type-III (8-iso-prostaglandin F2alpha) on human saphenous veins. 2000 J. Cardiovasc. Pharmacol. pmid:10813374
Suntres ZE and Shek PN Prophylaxis against lipopolysaccharide-induced lung injuries by liposome-entrapped dexamethasone in rats. 2000 Biochem. Pharmacol. pmid:10704946
Cryer B et al. Effects of cutaneous aspirin on the human stomach and duodenum. 1999 Sep-Oct Proc. Assoc. Am. Physicians pmid:10519166
Stewart KG et al. Estrogen decreases prostaglandin H synthase products from endothelial cells. 1999 Nov-Dec J. Soc. Gynecol. Investig. pmid:10643586
Tong H et al. Prostaglandin endoperoxide synthase-2 abundance is increased in brain tissues of late-gestation fetal sheep in response to cerebral hypoperfusion. 1999 May-Jun J. Soc. Gynecol. Investig. pmid:10376268
Uriu K et al. Effect of acute thromboxane A2 inhibition on the renal hemodynamics in a spontaneously non-insulin-dependent diabetic rat, Otsuka Long-Evans Tokushima Fatty rat. 1999 Jul-Aug J. Diabetes Complicat. pmid:10616856
Pestana M et al. Kidney graft-infiltrating cells synthesize significantly higher amounts of prostaglandin E2 pre and during acute rejection. 1999 Feb-Mar Transplant. Proc. pmid:10083119
van den Dorpel MA et al. Beneficial effects of conversion from cyclosporine to azathioprine on fibrinolysis in renal transplant recipients. 1999 Feb-Mar Transplant. Proc. pmid:10083130
Duan M et al. Factors involved in the neuronal death during postischemic reperfusion: experimental study in rabbits. 1999 Chin. Med. J. pmid:11593584
Williams CA et al. The flavonoids of Tanacetum parthenium and T. vulgare and their anti-inflammatory properties. 1999 Phytochemistry pmid:10382317
Li S et al. [The experimental investigation on the preventive effects of API0134 against the re-occlusion of coronary arteries after therapeutic thrombolysis in dogs]. 1999 J. Tongji Med. Univ. pmid:12840851
Kawano K et al. Superiority of platelet integrin GPIIb-IIIa receptor antagonist over aspirin in preventing cyclic flow reductions in the guinea pig middle cerebral artery. 1999 Eur. J. Pharmacol. pmid:10422782
Dirig DM and Yaksh TL In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin. 1999 Br. J. Pharmacol. pmid:10217526
Bowers W et al. Artificial human skin: cytokine, prostaglandin, Hsp70 and histological responses to heat exposure. 1999 J. Dermatol. Sci. pmid:10397388
Heidemann SM et al. Ibuprofen attenuates cardiopulmonary dysfunction by modifying vascular tone in endotoxemia. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10359020
Dong Y et al. [Quantitive study of 6-keto-prostaglandin F1 alpha and thromboxane B2 in human pulp]. 1999 Zhonghua Kou Qiang Yi Xue Za Zhi pmid:11776916
Saareks V et al. Nicotinic acid and pyridoxine modulate arachidonic acid metabolism in vitro and ex vivo in man. 1999 Pharmacol. Toxicol. pmid:10401729
Mita H et al. Generation of thromboxane A2 from highly purified human sinus mast cells after immunological stimulation. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10359019
Mayer AM et al. Escherichia coli lipopolysaccharide potentiation and inhibition of rat neonatal microglia superoxide anion generation: correlation with prior lactic dehydrogenase, nitric oxide, tumor necrosis factor-alpha, thromboxane B2, and metalloprotease release. 1999 Shock pmid:10188770
Kay-Mugford T and Conlon P Possible inconsistencies in study on cyclooxygenase. 1999 Am. J. Vet. Res. pmid:10188806
Michelson AD et al. The effects of aspirin and hypothermia on platelet function in vivo. 1999 Br. J. Haematol. pmid:10027713
Hirakata H et al. Propofol has both enhancing and suppressing effects on human platelet aggregation in vitro. 1999 Anesthesiology pmid:10551587
Heller A et al. Pancreatitis-associated protein protects the lung from leukocyte-induced injury. 1999 Anesthesiology pmid:10551593
Kim HS et al. Effects of tetrandrine and fangchinoline on human platelet aggregation and thromboxane B2 formation. 1999 J Ethnopharmacol pmid:10433485
van Kooten F et al. Increased thromboxane biosynthesis is associated with poststroke dementia. 1999 Stroke pmid:10436098
Peredo HA et al. Time-course of the alterations in prostanoid production and in contractile responses of mesenteric beds isolated from streptozotocin diabetic rats. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10397409