Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Aortic Arch Syndromes D001015 2 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Edema, Cardiac D004489 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Yang Deficiency D016711 3 associated lipids
Bluetongue D001819 1 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Foot Rot D005535 1 associated lipids
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Zhang J et al. [Isolation of resisting thrombus and arteriosclerosis compounds in leaves of Salix matsudana]. 1999 Zhong Yao Cai pmid:12575095
Pearl JM et al. Effect of modified ultrafiltration on plasma thromboxane B2, leukotriene B4, and endothelin-1 in infants undergoing cardiopulmonary bypass. 1999 Ann. Thorac. Surg. pmid:10543508
Duan M et al. Factors involved in the neuronal death during postischemic reperfusion: experimental study in rabbits. 1999 Chin. Med. J. pmid:11593584
MacKay RJ et al. Effect of a conjugate of polymyxin B-dextran 70 in horses with experimentally induced endotoxemia. 1999 Am. J. Vet. Res. pmid:9918150
Fredenrich A et al. Effects of low density and high density lipoproteins isolated from non-insulin dependent diabetic patients on prostaglandin secretion by mouse macrophage cell line P388D1. 1999 Atherosclerosis pmid:9920525
Williams CA et al. The flavonoids of Tanacetum parthenium and T. vulgare and their anti-inflammatory properties. 1999 Phytochemistry pmid:10382317
Chou TC and Li CY Inhibitory mechanisms of dantrolene on platelet aggregation. 1999 Thromb. Res. pmid:10593433
Tanaka H et al. Leukotriene (LT)-receptor antagonist is more effective in asthmatic patients with a low baseline ratio of urinary LTE4 to 2,3-dinor-6-keto-prostaglandin (PG)F1alpha. 1999 Allergy pmid:10380781
Monneret G et al. Renal effects of cP450 arachidonate metabolites in the Lyon hypertensive rat. 1999 Fundam Clin Pharmacol pmid:10226768
Hanaoka M et al. Interferon-alpha elevates pulmonary blood pressure in sheep--the role of thromboxane cascade. 1999 Eur. J. Pharmacol. pmid:10323263
Chen G et al. [The effect of the molecular triggers of hemostatic activity on thrombosis in early stage of electrical injuries]. 1999 Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi pmid:11501103
Heindl B et al. The volatile anesthetic sevoflurane mitigates cardiodepressive effects of platelets in reperfused hearts. 1999 Basic Res. Cardiol. pmid:10326658
Licker M et al. Chronic angiotensin converting inhibition does not influence renal hemodynamic and function during cardiac surgery. 1999 Can J Anaesth pmid:10442956
Agnoli GC et al. Renal function and urinary prostanoid excretions in salt-depleted women: comparative effects of enalapril and indomethacin treatments. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10328327
Chahine R et al. The anti-thromboxane A2 synthetase activity of myocardial tissue and its variation during ischemia and reperfusion in isolated rabbit heart. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10328329
Peredo HA and Filinger EJ Effect of dipyridamole on prostanoid production in rat isolated atria. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10328333
Liguori A et al. Loop diuretics enhance the secretion of prostacyclin in vitro, in healthy persons, and in patients with chronic heart failure. 1999 Eur. J. Clin. Pharmacol. pmid:10335906
Davis KA et al. Prostanoids: early mediators in the secondary injury that develops after unilateral pulmonary contusion. 1999 J Trauma pmid:10338399
Ishihara S et al. Effects of long-term hemofiltration on circulating mediators and superoxide production during continuous endotoxin administration. 1999 J Trauma pmid:10338409
Li S et al. [The experimental investigation on the preventive effects of API0134 against the re-occlusion of coronary arteries after therapeutic thrombolysis in dogs]. 1999 J. Tongji Med. Univ. pmid:12840851
Tegeder I et al. Comparison of inhibitory effects of meloxicam and diclofenac on human thromboxane biosynthesis after single doses and at steady state. 1999 Clin. Pharmacol. Ther. pmid:10340919
Stanczyk FZ et al. Effect of oral contraceptives containing 20 and 35 micrograms ethinyl estradiol on urinary prostacyclin and thromboxane metabolite levels in smokers and nonsmokers. 1999 Contraception pmid:10342082
Vijaya Kumar M et al. The anhydrous milk fat, ghee, lowers serum prostaglandins and secretion of leukotrienes by rat peritoneal macrophages. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10574649
De La Cruz JP et al. Antiplatelet effect of the anaesthetic drug propofol: influence of red blood cells and leucocytes. 1999 Br. J. Pharmacol. pmid:10602334
Mercer JB et al. The effect of short-term cold exposure on risk factors for cardiovascular disease. 1999 Thromb. Res. pmid:10418798
Ferro D et al. Determinants of enhanced thromboxane biosynthesis in patients with systemic lupus erythematosus. 1999 Arthritis Rheum. pmid:10616019
Kawano K et al. Superiority of platelet integrin GPIIb-IIIa receptor antagonist over aspirin in preventing cyclic flow reductions in the guinea pig middle cerebral artery. 1999 Eur. J. Pharmacol. pmid:10422782
Dirig DM and Yaksh TL In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin. 1999 Br. J. Pharmacol. pmid:10217526
Miura M and Kurimoto F [Thromboxane B2 (TXB2)]. 1999 Nippon Rinsho pmid:10635957
Bowers W et al. Artificial human skin: cytokine, prostaglandin, Hsp70 and histological responses to heat exposure. 1999 J. Dermatol. Sci. pmid:10397388
Heidemann SM et al. Ibuprofen attenuates cardiopulmonary dysfunction by modifying vascular tone in endotoxemia. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10359020
Lees P et al. A pharmacodynamic and pharmacokinetic study with vedaprofen in an equine model of acute nonimmune inflammation. 1999 J. Vet. Pharmacol. Ther. pmid:10372594
Giuliano F and Warner TD Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs. 1999 Br. J. Pharmacol. pmid:10372826
Fukushima C et al. In vitro responses to antigen stimulation: comparison between human lung parenchyma resected from asthmatic patients and non-asthmatic patients. 1999 Ann. Allergy Asthma Immunol. pmid:10071522
Landoni MF et al. Enantiospecific pharmacokinetics and pharmacodynamics of ketoprofen in sheep. 1999 J. Vet. Pharmacol. Ther. pmid:10651463
Praticó D et al. Iron-dependent human platelet activation and hydroxyl radical formation: involvement of protein kinase C. 1999 Circulation pmid:10377074
Castellani S et al. Impaired renal adaptation to stress in the elderly with isolated systolic hypertension. 1999 Hypertension pmid:10567190
Gallery ED et al. In vitro human decidual endothelial cell thromboxane secretion in preeclampsia is not abnormal. 1999 Hypertens Pregnancy pmid:10586525
Pavord ID et al. Induced sputum eicosanoid concentrations in asthma. 1999 Am. J. Respir. Crit. Care Med. pmid:10588604
Kohda N et al. Effect of cilostazol, a phosphodiesterase III inhibitor, on experimental thrombosis in the porcine carotid artery. 1999 Thromb. Res. pmid:10593428
Truitt A et al. Antiplatelet effects of conjugated linoleic acid isomers. 1999 Biochim. Biophys. Acta pmid:10320806
Chakraborti T et al. Age-dependent change in arachidonic acid metabolic capacity in rat alveolar macrophages. 1999 Biochem. Mol. Biol. Int. pmid:10204087
Dong Y et al. [Quantitive study of 6-keto-prostaglandin F1 alpha and thromboxane B2 in human pulp]. 1999 Zhonghua Kou Qiang Yi Xue Za Zhi pmid:11776916
Saareks V et al. Nicotinic acid and pyridoxine modulate arachidonic acid metabolism in vitro and ex vivo in man. 1999 Pharmacol. Toxicol. pmid:10401729
Kanji VK et al. Vitamin E suppresses cyclosporine A-induced increase in the urinary excretion of arachidonic acid metabolites including F2-isoprostanes in the rat model. 1999 Transplant. Proc. pmid:10331052
McAdam BF et al. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:9874808
Morrow JD et al. Increased formation of thromboxane in vivo in humans with mastocytosis. 1999 J. Invest. Dermatol. pmid:10417625
Catella-Lawson F et al. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. 1999 J. Pharmacol. Exp. Ther. pmid:10215647
Mills JL et al. Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. 1999 JAMA pmid:10432033
Holt S et al. Acute cholestasis-induced renal failure: effects of antioxidants and ligands for the thromboxane A2 receptor. 1999 Kidney Int. pmid:9893136
Mizugaki M et al. Monitoring of the thromboxane A2/prostacyclin ratio in the urine of patients with retinal vascular occlusion through the low-dose-aspirin therapy using the gas chromatography/selected ion monitoring method. 1999 Prostaglandins Other Lipid Mediat. pmid:10593167
Hishinuma T et al. Urinary thromboxane A2/prostacyclin balance reflects the pathological state of a diabetic. 1999 Prostaglandins Other Lipid Mediat. pmid:10593168
Hoch B and Bernhard M Reduced prostacyclin to thromboxane A2 ratio is correlated with central apneas in preterm infants. 1999 Prostaglandins Other Lipid Mediat. pmid:10593170
Mita H et al. Generation of thromboxane A2 from highly purified human sinus mast cells after immunological stimulation. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10359019
van Kooten F et al. Increased platelet activation in the chronic phase after cerebral ischemia and intracerebral hemorrhage. 1999 Stroke pmid:10066850
Langberg H et al. Metabolism and inflammatory mediators in the peritendinous space measured by microdialysis during intermittent isometric exercise in humans. 1999 J. Physiol. (Lond.) pmid:10066916
Gonchar M et al. Kinetics of prostanoid synthesis by macrophages is regulated by arachidonic acid sources. 1999 Eur. J. Biochem. pmid:10504410
Takahashi H et al. Ureteral obstruction reverses glomerular proliferation in immune complex glomerulonephritis. 1999 J. Lab. Clin. Med. pmid:10072261
Fujimoto Y et al. Sphingomyelin inhibits platelet 12-lipoxygenase activity. 1999 Eur. J. Pharmacol. pmid:10478636
Hu MK et al. Synthesis and evaluation of backbone/amide-modified analogs of leualacin. 1999 Bioorg. Med. Chem. Lett. pmid:10098664
Yamamoto T et al. Production of prostanoids and nitric oxide by infarcted heart in situ and the effect of aspirin. 1999 Biochem. Biophys. Res. Commun. pmid:10198239
Mayer AM et al. Escherichia coli lipopolysaccharide potentiation and inhibition of rat neonatal microglia superoxide anion generation: correlation with prior lactic dehydrogenase, nitric oxide, tumor necrosis factor-alpha, thromboxane B2, and metalloprotease release. 1999 Shock pmid:10188770
Yang SY and Gao ZX Determination and clinical significance of plasma levels of prostaglandins in patients with acute brain injury. 1999 Surg Neurol pmid:10511080
Kay-Mugford T and Conlon P Possible inconsistencies in study on cyclooxygenase. 1999 Am. J. Vet. Res. pmid:10188806
Michelson AD et al. The effects of aspirin and hypothermia on platelet function in vivo. 1999 Br. J. Haematol. pmid:10027713
van Genderen PJ et al. Thromboxane-dependent platelet activation in vivo precedes arterial thrombosis in thrombocythaemia: a rationale for the use of low-dose aspirin as an antithrombotic agent. 1999 Br. J. Haematol. pmid:10086775
Takao A et al. Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma. 1999 Ann. Allergy Asthma Immunol. pmid:10227338
Andrieu S et al. Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs. 1999 J. Cardiovasc. Pharmacol. pmid:10028935
Denizot Y et al. Are lipid mediators implicated in the production of pro- and anti-inflammatory cytokines during cardiopulmonary bypass graft with extracorporeal circulation? 1999 Cytokine pmid:10328869
Kitagawa M et al. The role of the spleen, especially regarding changes in both thromboxane A2 and the remnant liver dysfunction after extensive hepatectomy. 1999 Surg. Today pmid:10030738
Serebruany VL and Gurbel PA Assessment of platelet activity by measuring platelet-derived substances in plasma from patients with acute myocardial infarction: surprising lessons from the GUSTO-III Platelet Study. 1999 Thromb. Res. pmid:10030832
Nawarskas JJ et al. Effect of aspirin on blood pressure in hypertensive patients taking enalapril or losartan. 1999 Am. J. Hypertens. pmid:10480471
Nishimaki S and Seki K An imbalance between prostacyclin and thromboxane in relation to cerebral blood flow in neonates with maternal preeclampsia. 1999 Prostaglandins Other Lipid Mediat. pmid:10482286
Chou TC et al. Antiplatelet effect of amlodipine: a possible mechanism through a nitric oxide-mediated process. 1999 Biochem. Pharmacol. pmid:10535758
Feldman M and Cryer B Aspirin absorption rates and platelet inhibition times with 325-mg buffered aspirin tablets (chewed or swallowed intact) and with buffered aspirin solution. 1999 Am. J. Cardiol. pmid:10468077
Obata T et al. Simultaneous assay of prostaglandins and thromboxane in the cerebrospinal fluid by gas chromatography-mass spectrometry-selected ion monitoring. 1999 J. Chromatogr. B Biomed. Sci. Appl. pmid:10491991
Gust R et al. Role of cyclooxygenase-2 in oleic acid-induced acute lung injury. 1999 Am. J. Respir. Crit. Care Med. pmid:10508803
Thakur V et al. Antihypertensive effect of the combination of fosinopril and HCTZ is resistant to interference by nonsteroidal antiinflammatory drugs. 1999 Am. J. Hypertens. pmid:10509552
Véricel E et al. The influence of low intake of n-3 fatty acids on platelets in elderly people. 1999 Atherosclerosis pmid:10525140
Sayar K and Melli M Effect of combination of misoprostol and indomethacin on eicosanoid production in carrageenan-induced air pouch inflammation in rats. 1999 Eur. J. Pharmacol. pmid:10225376
Pirich C et al. Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. 1999 Thromb. Res. pmid:10588465
Davì G et al. In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation. 1999 Circulation pmid:9892587
Serebruany VL et al. Effects of a novel Mac-1 inhibitor, NPC 15669, on hemostatic parameters during preconditioned myocardial infarction. 1999 Life Sci. pmid:10530802
de Meijer A et al. Meloxicam, 15 mg/day, spares platelet function in healthy volunteers. 1999 Clin. Pharmacol. Ther. pmid:10546927
Reeves JH et al. Continuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group. 1999 Crit. Care Med. pmid:10548188
Nemcova S et al. Cyclic nucleotides and production of prostanoids in human varicose veins. 1999 J. Vasc. Surg. pmid:10550185
Hirakata H et al. Propofol has both enhancing and suppressing effects on human platelet aggregation in vitro. 1999 Anesthesiology pmid:10551587
Heller A et al. Pancreatitis-associated protein protects the lung from leukocyte-induced injury. 1999 Anesthesiology pmid:10551593
Kim HS et al. Effects of tetrandrine and fangchinoline on human platelet aggregation and thromboxane B2 formation. 1999 J Ethnopharmacol pmid:10433485
van Kooten F et al. Increased thromboxane biosynthesis is associated with poststroke dementia. 1999 Stroke pmid:10436098
Ricetti MM et al. Effects of sodium selenite on in vitro interactions between platelets and endothelial cells. 1999 Int. J. Clin. Lab. Res. pmid:10436266
Tsugawa K et al. A selective cyclo-oxygenase-2 inhibitor, NS-398, may improve portal hypertension without inducing gastric mucosal injury. 1999 J. Gastroenterol. Hepatol. pmid:10440208
Zhang S et al. Effects of acupuncture on the levels of endothelin, TXB2, and 6-keto-PGF1 alpha in apoplexy patients. 1999 J Tradit Chin Med pmid:10453582
Arakida Y et al. Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs. 1999 J. Pharmacol. Exp. Ther. pmid:10454505
Melton SM et al. Mediator-dependent secondary injury after unilateral blunt thoracic trauma. 1999 Shock pmid:10454828
Sheu JR et al. The antiplatelet activity of PMC, a potent alpha-tocopherol analogue, is mediated through inhibition of cyclo-oxygenase. 1999 Br. J. Pharmacol. pmid:10455267
Jiménez R et al. Involvement of thromboxane A2 in the endothelium-dependent contractions induced by myricetin in rat isolated aorta. 1999 Br. J. Pharmacol. pmid:10455307
Perneby C et al. Optimization of an enzyme immunoassay for 11-dehydro-thromboxane B(2) in urine: comparison with GC-MS. 1999 Thromb. Res. pmid:10632465
Hayashi N et al. Effect of intravenous omega-6 and omega-3 fat emulsions on nitrogen retention and protein kinetics in burned rats. 1999 Nutrition pmid:9990578
Peredo HA et al. Time-course of the alterations in prostanoid production and in contractile responses of mesenteric beds isolated from streptozotocin diabetic rats. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10397409