| MeSH term | MeSH ID | Detail |
|---|---|---|
| Aortic Arch Syndromes | D001015 | 2 associated lipids |
| Mixed Connective Tissue Disease | D008947 | 2 associated lipids |
| Edema, Cardiac | D004489 | 1 associated lipids |
| Oligomenorrhea | D009839 | 1 associated lipids |
| Yang Deficiency | D016711 | 3 associated lipids |
| Bluetongue | D001819 | 1 associated lipids |
| Retinal Vein Occlusion | D012170 | 2 associated lipids |
| Foot Rot | D005535 | 1 associated lipids |
| Frostbite | D005627 | 1 associated lipids |
| Strongyle Infections, Equine | D013319 | 1 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ikemura T et al. | KW-4679, an antiallergic drug, inhibits the production of inflammatory lipids in human polymorphonuclear leukocytes and guinea pig eosinophils. | 1996 | Int. Arch. Allergy Immunol. | pmid:8645979 |
| Leung LK and Glauert HP | Reduction of the concentrations of prostaglandins E2 and F2alpha, and thromboxane B2 in cultured rat hepatocytes treated with the peroxisome proliferator ciprofibrate. | 1996 | Toxicol. Lett. | pmid:8644126 |
| Saji T et al. | [Short- and long-term effects of the new oral prostacyclin analogue, beraprost sodium, in patients with severe pulmonary hypertension]. | 1996 | J Cardiol | pmid:8642506 |
| Thwaites BK et al. | Intravenous ketorolac tromethamine worsens platelet function during knee arthroscopy under spinal anesthesia. | 1996 | Anesth. Analg. | pmid:8638787 |
| Garvin PJ et al. | Evaluation of the thromboxane A2 synthetase inhibitor OKY-046 in a warm ischemia-reperfusion rat model. | 1996 | Transplantation | pmid:8633364 |
| Suehiro T et al. | Thromboxane A2 in preservation-reperfusion injury: the effect of thromboxane A2 synthetase inhibitor. | 1996 | J. Surg. Res. | pmid:8632642 |
| Jacoby RF et al. | Chemoprevention of spontaneous intestinal adenomas in the Apc Min mouse model by the nonsteroidal anti-inflammatory drug piroxicam. | 1996 | Cancer Res. | pmid:8631000 |
| McAdam B et al. | Transdermal modification of platelet function: an aspirin patch system results in marked suppression of platelet cyclooxygenase. | 1996 | J. Pharmacol. Exp. Ther. | pmid:8627531 |
| Korn RL et al. | The effects of Carmeda Bioactive Surface on human blood components during simulated extracorporeal circulation. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8622305 |
| Hirashima Y et al. | Prevention of cerebrovasospasm following subarachnoid hemorrhage in rabbits by the platelet-activating factor antagonist, E5880. | 1996 | J. Neurosurg. | pmid:8622157 |
| Praticó D and FitzGerald GA | Generation of 8-epiprostaglandin F2alpha by human monocytes. Discriminate production by reactive oxygen species and prostaglandin endoperoxide synthase-2. | 1996 | J. Biol. Chem. | pmid:8621535 |
| Awni WM et al. | The pharmacokinetic and pharmacodynamic interactions between the 5-lipoxygenase inhibitor zileuton and the cyclo-oxygenase inhibitor naproxen in human volunteers. | 1995 | Clin Pharmacokinet | pmid:8620667 |
| Osterud B et al. | Effect of marine oils supplementation on coagulation and cellular activation in whole blood. | 1995 | Lipids | pmid:8614301 |
| Aune B et al. | Hormone replacement therapy reduces the reactivity of monocytes and platelets in whole blood--a beneficial effect on atherogenesis and thrombus formation? | 1995 | Am. J. Obstet. Gynecol. | pmid:8610768 |
| Kritz H et al. | Isradipine increases vascular prostaglandin I2-formation while the thromboxane B2-synthesis is diminished. | 1995 | Thromb. Res. | pmid:8610276 |
| Cochran JB et al. | Age-related mortality and adherent splenic cell mediator production to endotoxin in the rat. | 1995 | Shock | pmid:8608403 |
| Rocca B et al. | Increased thromboxane biosynthesis in essential thrombocythemia. | 1995 | Thromb. Haemost. | pmid:8607099 |
| Tarnow P et al. | Effects of D-myo-Inositol-1,2,6-triphosphate on eicosanoid formation in burned skin. | 1996 | J. Surg. Res. | pmid:8606494 |
| Huang JZ et al. | Study on characteristics of blast-fragment combined injury in dogs. | 1996 | J Trauma | pmid:8606426 |
| Sanderud J et al. | D-penicillamine inhibits the action of reactive oxygen species in the pig pulmonary circulation. | 1995 | J Perinat Med | pmid:8606345 |
| Sreedhara R et al. | Uremic patients have decreased shear-induced platelet aggregation mediated by decreased availability of glycoprotein IIb-IIIa receptors. | 1996 | Am. J. Kidney Dis. | pmid:8604704 |
| Makheia AN et al. | Inhibition of platelet aggregation and thromboxane synthesis by onion and garlic. | 1979 | Lancet | pmid:86023 |
| Jesse RL et al. | Dehydroepiandrosterone inhibits human platelet aggregation in vitro and in vivo. | 1995 | Ann. N. Y. Acad. Sci. | pmid:8597466 |
| Berti F et al. | Protective effect of furosemide combined with non-steroidal anti-inflammatory drugs administered by inhalation route on guinea-pigs anaphylaxis model. | 1995 | Arzneimittelforschung | pmid:8595068 |
| Murray MJ et al. | Select dietary fatty acids attenuate cardiopulmonary dysfunction during acute lung injury in pigs. | 1995 | Am. J. Physiol. | pmid:8594921 |
| Landoni MF and Lees P | Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in calves. | 1995 | Chirality | pmid:8593252 |
| Yokoyama I et al. | Beneficial effect of donor pretreatment with thromboxane A2 synthase inhibitor on the graft survival in pig liver transplantation. | 1996 | J. Surg. Res. | pmid:8592420 |
| Zhou W et al. | Evidence for altered cellular calcium in the pathogenetic mechanism of acute pancreatitis in rats. | 1996 | J. Surg. Res. | pmid:8592406 |
| Pfister SL and Campbell WB | Role of endothelium-derived metabolites of arachidonic acid in enhanced pulmonary artery contractions in female rabbits. | 1996 | Hypertension | pmid:8591886 |
| Pettigrew LC et al. | Delayed elevation of platelet activating factor in ischemic hippocampus. | 1995 | Brain Res. | pmid:8590061 |
| Jawerbaum A et al. | Hyperglycemia promotes elevated generation of TXA2 in isolated rat uteri. | 1995 | Prostaglandins | pmid:8588071 |
| Myers SI et al. | Platelet activating factor (PAF) stimulates release of PGI2 from inflamed rabbit gallbladder cell cultures. | 1995 | Prostaglandins | pmid:8588069 |
| Kane GC et al. | Insights into IgE-mediated lung inflammation derived from a study employing a 5-lipoxygenase inhibitor. | 1995 | Prostaglandins | pmid:8588068 |
| Landoni MF et al. | Pharmacokinetics and pharmacodynamics of ketoprofen in calves applying PK/PD modelling. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8587147 |
| Cargile JL et al. | Effects of tumor necrosis factor blockade on interleukin 6, lactate, thromboxane, and prostacyclin responses in miniature horses given endotoxin. | 1995 | Am. J. Vet. Res. | pmid:8585654 |
| Habib A et al. | Increased expression of inducible cyclooxygenase-2 in human endothelial cells by antiphospholipid antibodies. | 1995 | Thromb. Haemost. | pmid:8585020 |
| Davì G et al. | Demonstration of Rickettsia Conorii-induced coagulative and platelet activation in vivo in patients with Mediterranean spotted fever. | 1995 | Thromb. Haemost. | pmid:8584998 |
| Friedman M et al. | Neutrophil adhesion blockade with NPC 15669 decreases pulmonary injury after total cardiopulmonary bypass. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8583821 |
| Hsu LY et al. | 2-Heteroaryl 2-substituted phenylketone derivatives and their inhibitory activity on platelet aggregation. | 1995 | J. Pharm. Pharmacol. | pmid:8583390 |
| Panara MR et al. | Effects of the novel anti-inflammatory compounds, N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulphonamide (NS-398) and 5-methanesulphonamido-6-(2,4-difluorothio-phenyl)-1-inda none (L-745,337), on the cyclo-oxygenase activity of human blood prostaglandin endoperoxide synthases. | 1995 | Br. J. Pharmacol. | pmid:8581280 |
| Lu CS et al. | [Experimental study on anti-atherosclerotic effect of tongmai jiangzhi oral liquor]. | 1995 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8580696 |
| Lin Y | Vasoactive intestinal polypeptide prevents injury of pulmonary vascular permeability due to xanthine with xanthine oxidase. | 1995 | Chin. Med. Sci. J. | pmid:8580482 |
| Cenni E et al. | Platelet and coagulation factor variations induced in vitro by polyethylene terephthalate (Dacron) coated with pyrolytic carbon. | 1995 | Biomaterials | pmid:8580259 |
| Patrono C et al. | Characterization of biochemical and functional effects of antiplatelet drugs as a key to their clinical development. | 1995 | Thromb. Haemost. | pmid:8578493 |
| Gold MS et al. | Hyperalgesic agents increase a tetrodotoxin-resistant Na+ current in nociceptors. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8577723 |
| Somova L | Effects of iloprost on salt-sensitive Dahl rats. | 1995 | Methods Find Exp Clin Pharmacol | pmid:8577205 |
| Gil B et al. | Effects of marine 2-polyprenyl-1,4-hydroquinones on phospholipase A2 activity and some inflammatory responses. | 1995 | Eur. J. Pharmacol. | pmid:8575515 |
| Kanamori S et al. | Effects of dietary fibre on dimethylhydrazine-induced changes in prostanoid concentrations in rat colonic mucosa. | 1995 | Clin. Exp. Pharmacol. Physiol. | pmid:8575110 |
| Lin Y and Sun M | [Vasoactive intestinal polypeptide prevents injury of pulmonary vascular permeability due to xanthine with xanthine oxidase]. | 1995 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:8575046 |
| Umeda F et al. | Prostaglandins and diabetic nephropathy. | 1995 Oct-Dec | J. Diabetes Complicat. | pmid:8573760 |
| Nakano T et al. | Effects of platelet depletion on PMA-induced acute lung injury in awake sheep. | 1995 | Respir Physiol | pmid:8570923 |
| Sorem KA and Siler-Khodr TM | Placental prostanoid release in severe intrauterine growth retardation. | 1995 | Placenta | pmid:8570572 |
| Kobayashi I et al. | Saiboku-To, a herbal extract mixture, selectively inhibits 5-lipoxygenase activity in leukotriene synthesis in rat basophilic leukemia-1 cells. | 1995 | J Ethnopharmacol | pmid:8569245 |
| Altavilla D et al. | G 619, a dual thromboxane synthase inhibitor and thromboxane A2 receptor antagonist, inhibits tumor necrosis factor-alpha biosynthesis. | 1995 | Eur. J. Pharmacol. | pmid:8566149 |
| Glaser K et al. | Etodolac selectively inhibits human prostaglandin G/H synthase 2 (PGHS-2) versus human PGHS-1. | 1995 | Eur. J. Pharmacol. | pmid:8566109 |
| Kawikova I et al. | Bradykinin-induced release of thromboxane B2 into bronchoalveolar lavage fluid of guinea pigs: relationship to airflow obstruction. | 1995 | Eur. J. Pharmacol. | pmid:8566097 |
| Satterwhite JH and Boudinot FD | Effects of age on the pharmacodynamics of naproxen in the rat. | 1995 Sep-Oct | Exp. Gerontol. | pmid:8557098 |
| Liu W et al. | [Effects of selenium and vitamin E on arachidonic acid metabolism in experimental myocardial ischaemia]. | 1995 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:8556938 |
| Wang TL et al. | The evolution of platelet aggregability in patients undergoing catheter ablation for supraventricular tachycardia with radiofrequency energy: the role of antiplatelet therapy. | 1995 | Pacing Clin Electrophysiol | pmid:8552510 |
| Morioka K et al. | Leukocyte and platelet depletion with a blood cell separator: effects on lung injury after cardiac surgery with cardiopulmonary bypass. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8551788 |
| Kato A et al. | Role of thromboxane A2 and prostacyclin in uninephrectomy-induced attenuation of ischemic renal injury. | 1995 | Kidney Int. | pmid:8544417 |
| Daugschies A | Oesophagostomum dentatum: population dynamics and synthesis of prostanoids by histotropic stages cultured in vitro. | 1995 | Exp. Parasitol. | pmid:8542999 |
| Lees P et al. | Pharmacodynamics and pharmacokinetics of carprofen in the horse. | 1994 | Equine Vet. J. | pmid:8542839 |
| Blache D et al. | Occurrence and biological effects of cholesteryl sulfate on blood platelets. | 1995 | Biochim. Biophys. Acta | pmid:8541337 |
| Shimizu Y et al. | Nafamostat mesilate prevents warm ischemia-reperfusion injury in canine pancreas autotransplantation. | 1995 | Transplant. Proc. | pmid:8539906 |
| Landoni MF and Lees P | Comparison of the anti-inflammatory actions of flunixin and ketoprofen in horses applying PK/PD modelling. | 1995 | Equine Vet. J. | pmid:8536660 |
| Smith AJ et al. | Hypertensive and normal pregnancy: a longitudinal study of blood pressure, distensibility of dorsal hand veins and the ratio of the stable metabolites of thromboxane A2 and prostacyclin in plasma. | 1995 | Br J Obstet Gynaecol | pmid:8534627 |
| Narita S et al. | [Studies on thromboxane B2 level in nasal lavage fluid after antigen challenge in patients with allergic rhinitis and guinea pig models]. | 1995 | Arerugi | pmid:8534212 |
| Vezza R et al. | Thromboxane synthase inhibitors suppress more effectively the aggregation of thromboxane receptor-desensitized than that of normal platelets: role of adenylylcyclase up-regulation. | 1995 | J. Pharmacol. Exp. Ther. | pmid:8531121 |
| Itoh K et al. | Relationship between airway eosinophilia and airway hyperresponsiveness in a late asthmatic model of guinea pigs. | 1996 | Int. Arch. Allergy Immunol. | pmid:8527956 |
| Nosál R et al. | The H1-histamine receptor antagonist dithiaden inhibits stimulated platelet aggregation, malondialdehyde formation and thromboxane production in vitro. | 1995 | Inflamm. Res. | pmid:8520978 |
| Eisenmann CJ and Miller RK | Cadmium and glutathione: effect on human placental thromboxane and prostacyclin production. | 1995 Jan-Feb | Reprod. Toxicol. | pmid:8520130 |
| Rabinovici R et al. | ARDS-like lung injury produced by endotoxin in platelet-activating factor-primed rats. | 1993 | J. Appl. Physiol. | pmid:8514698 |
| Renz H et al. | Tumor necrosis factor-alpha, interleukin 1, eicosanoid, and hydrogen peroxide release from macrophages exposed to glove starch particles. | 1993 | Clin. Immunol. Immunopathol. | pmid:8513589 |
| Dunn CW and Horton JW | Role of angiotensin II in neonatal sepsis. | 1993 | Circ. Shock | pmid:8508519 |
| Fletcher JR et al. | Tumor necrosis factor-induced mortality is reversed with cyclooxygenase inhibition. | 1993 | Ann. Surg. | pmid:8507112 |
| Fisher M | Increased thromboxane biosynthesis in patients with acute cerebral ischemia. | 1993 | Stroke | pmid:8506568 |
| Budd JS et al. | The effectiveness of low dose slow release aspirin as an antiplatelet agent. | 1993 | J R Soc Med | pmid:8505747 |
| Penning LC et al. | Ca(2+)-mediated prostaglandin E2 induction reduces haematoporphyrin-derivative-induced cytotoxicity of T24 human bladder transitional carcinoma cells in vitro. | 1993 | Biochem. J. | pmid:8503851 |
| Ferretti A et al. | Ingestion of marine oil reduces excretion of 11-dehydrothromboxane B2, an index of intravascular production of thromboxane A2. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8497491 |
| Ciabattoni G et al. | Effects of vasoactive intestinal polypeptide on antigen-induced bronchoconstriction and thromboxane release in guinea-pig lung. | 1993 | Br. J. Pharmacol. | pmid:8495242 |
| Schneidkraut MJ and Carlson RW | Cecal ligation and puncture is associated with pulmonary injury in the rat: role of cyclooxygenase pathway products. | 1993 | Prostaglandins | pmid:8493358 |
| Mustad VA et al. | Comparison of the effects of diets rich in stearic acid versus myristic acid and lauric acid on platelet fatty acids and excretion of thromboxane A2 and PGI2 metabolites in healthy young men. | 1993 | Metab. Clin. Exp. | pmid:8487669 |
| Zwischenberger JB et al. | Pathophysiology of ovine smoke inhalation injury treated with extracorporeal membrane oxygenation. | 1993 | Chest | pmid:8486048 |
| Yamanaka S et al. | 11-Dehydro thromboxane B2: a reliable parameter of thromboxane A2 production in dogs. | 1993 | Prostaglandins | pmid:8484010 |
| Alanko J | Effects of phenols on eicosanoid synthesis in A23187-stimulated human whole blood. | 1993 | Prostaglandins | pmid:8484008 |
| Yasu T et al. | Effects of aspirin DL-lysine on thrombin generation in unstable angina pectoris. | 1993 | Am. J. Cardiol. | pmid:8480641 |
| Böck M et al. | Storage of single-donor platelet concentrates: metabolic and functional changes. | 1993 | Transfusion | pmid:8480351 |
| Smith CC et al. | The influence of aspirin on plasma and platelet catecholamine levels, and platelet function in normal man. | 1993 | Clin. Auton. Res. | pmid:8477181 |
| Mohri H and Ohkubo T | Single-dose effect of enteric-coated aspirin on platelet function and thromboxane generation in middle-aged men. | 1993 | Ann Pharmacother | pmid:8477113 |
| Hauth JC et al. | Low-dose aspirin therapy to prevent preeclampsia. | 1993 | Am. J. Obstet. Gynecol. | pmid:8475955 |
| Arruzazabala ML et al. | Effects of Policosanol on platelet aggregation in rats. | 1993 | Thromb. Res. | pmid:8475481 |
| Ciabattoni G et al. | Aspirin, but not heparin, suppresses the transient increase in thromboxane biosynthesis associated with cardiac catheterization or coronary angioplasty. | 1993 | J. Am. Coll. Cardiol. | pmid:8473644 |
| Kroegel C and Matthys H | Platelet-activating factor-induced human eosinophil activation. Generation and release of cyclo-oxygenase metabolites in human blood eosinophils from asthmatics. | 1993 | Immunology | pmid:8473016 |
| Sagripanti A et al. | [The use of picotamide in nephropathy with mesangial IgA deposits. The effect on thromboxane generation]. | 1993 | Clin Ter | pmid:8472511 |
| Elmadfa I et al. | Influence of a single parenteral application of a 10% fish oil emulsion on plasma fatty acid pattern and the function of thrombocytes in young adult men. | 1993 | Ann. Nutr. Metab. | pmid:8470873 |
| GarcÃa-Valdecasas JC et al. | Prostaglandin metabolism and hemodynamic alterations during human liver transplantation. | 1993 | Transplant. Proc. | pmid:8470202 |
| Lueddeckens G et al. | Importance of secondary TXA2 release in mediating of endothelin-1 induced bronchoconstriction and vasopressin in the guinea-pig. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8469685 |
| Byrne JG et al. | Cardiac-derived thromboxane A2. An initiating mediator of reperfusion injury? | 1993 | J. Thorac. Cardiovasc. Surg. | pmid:8469003 |
| Grieve EM et al. | The reversal of experimental cyclosporin A nephrotoxicity by thromboxane synthetase inhibition. | 1993 | Biochem. Pharmacol. | pmid:8466554 |