| MeSH term | MeSH ID | Detail |
|---|---|---|
| Aortic Arch Syndromes | D001015 | 2 associated lipids |
| Mixed Connective Tissue Disease | D008947 | 2 associated lipids |
| Edema, Cardiac | D004489 | 1 associated lipids |
| Oligomenorrhea | D009839 | 1 associated lipids |
| Yang Deficiency | D016711 | 3 associated lipids |
| Bluetongue | D001819 | 1 associated lipids |
| Retinal Vein Occlusion | D012170 | 2 associated lipids |
| Foot Rot | D005535 | 1 associated lipids |
| Frostbite | D005627 | 1 associated lipids |
| Strongyle Infections, Equine | D013319 | 1 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kaneko I et al. | Prostaglandin F(2alpha) regulates cytokine responses of mast cells through the receptors for prostaglandin E. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18190789 |
| Parsons JP et al. | Airway inflammation in exercise-induced bronchospasm occurring in athletes without asthma. | 2008 | J Asthma | pmid:18569228 |
| Natarajan G et al. | Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants. | 2008 | Am J Perinatol | pmid:18726836 |
| Santilli F et al. | Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients. | 2008 | Blood | pmid:18541722 |
| Mitsopoulos P et al. | Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents. | 2008 | Int J Pharm | pmid:18694812 |
| Yokoyama Y et al. | Up-regulated thromboxane production in the rat liver with biliary obstruction does not contribute to promote hepatic injury. | 2008 | Shock | pmid:17885643 |
| Meen O et al. | No case of COX-1-related aspirin resistance found in 289 patients with symptoms of stable CHD remitted for coronary angiography. | 2008 | Scand. J. Clin. Lab. Invest. | pmid:17934975 |
| Zhao S et al. | Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies. | 2008 | Placenta | pmid:17936899 |
| Heistein LC et al. | Aspirin resistance in children with heart disease at risk for thromboembolism: prevalence and possible mechanisms. | 2008 | Pediatr Cardiol | pmid:17896127 |
| Lessa A et al. | The effect of pentoxifylline on the pulmonary response to high tidal volume ventilation in rats. | 2008 | Pulm Pharmacol Ther | pmid:17251044 |
| Aslam R et al. | Lipoproteins inhibit platelet aggregation and arachidonic acid metabolism in experimental hypercholesterolaemia. | 2008 | Clin. Exp. Pharmacol. Physiol. | pmid:18215184 |
| Toscano CD et al. | NMDA-induced seizure intensity is enhanced in COX-2 deficient mice. | 2008 | Neurotoxicology | pmid:18834901 |
| Lee CR et al. | Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. | 2008 | Clin. Pharmacol. Ther. | pmid:17495879 |
| Awad H et al. | Intracellular and extracellular expression of the major inducible 70kDa heat shock protein in experimental ischemia-reperfusion injury of the spinal cord. | 2008 | Exp. Neurol. | pmid:18511046 |
| Basselin M et al. | Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats. | 2008 | Neurochem. Res. | pmid:18461450 |
| Dobaczewski M et al. | Targeting the urine and plasma determinants of thromboxane A2 metabolism in detection of aspirin effectiveness. | 2008 | Blood Coagul. Fibrinolysis | pmid:18600093 |
| Rossoni G et al. | Combined simvastatin-manidipine protect against ischemia-reperfusion injury in isolated hearts from normocholesterolemic rats. | 2008 | Eur. J. Pharmacol. | pmid:18442813 |
| Park MK et al. | Antiplatelet and antithrombotic activity of indole-3-carbinol in vitro and in vivo. | 2008 | Phytother Res | pmid:17724769 |
| Helgason CM et al. | Platelet aggregation and recruitment with aspirin-clopidogrel therapy. | 2008 | Cerebrovasc. Dis. | pmid:18349532 |
| Momen A et al. | Local prostaglandin blockade attenuates muscle mechanoreflex-mediated renal vasoconstriction during muscle stretch in humans. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18326807 |
| Skoglund C et al. | C-reactive protein and C1q regulate platelet adhesion and activation on adsorbed immunoglobulin G and albumin. | 2008 | Immunol. Cell Biol. | pmid:18332893 |
| Menzies D et al. | Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma. | 2008 | J. Allergy Clin. Immunol. | pmid:18313127 |
| Geske FJ et al. | AspirinWorks: a new immunologic diagnostic test for monitoring aspirin effect. | 2008 | Mol Diagn Ther | pmid:18288882 |
| Selg E et al. | Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung. | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18294831 |
| Basselin M et al. | Chronic carbamazepine administration attenuates dopamine D2-like receptor-initiated signaling via arachidonic acid in rat brain. | 2008 | Neurochem. Res. | pmid:18302021 |
| Signore C et al. | Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day. | 2008 | Alcohol. Clin. Exp. Res. | pmid:18715278 |
| Roethig HJ et al. | A 12-month, randomized, controlled study to evaluate exposure and cardiovascular risk factors in adult smokers switching from conventional cigarettes to a second-generation electrically heated cigarette smoking system. | 2008 | J Clin Pharmacol | pmid:18319361 |
| Al-Salam Z et al. | The effect of dobutamine on platelet aggregatory function in newborn piglets with hypoxia and reoxygenation. | 2008 | Shock | pmid:18323735 |
| Park JW et al. | 15,16-dihydrotanshinone I, a major component from Salvia miltiorrhiza Bunge (Dansham), inhibits rabbit platelet aggregation by suppressing intracellular calcium mobilization. | 2008 | Arch. Pharm. Res. | pmid:18277607 |
| Schwartz JI et al. | Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects. | 2008 | J Clin Pharmacol | pmid:18434566 |
| Hasan J et al. | Early postnatal ibuprofen and indomethacin effects in suckling and weanling rat kidneys. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18096423 |
| Eikelboom JW et al. | Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: determinants and effect on cardiovascular risk. | 2008 | Circulation | pmid:18838564 |
| Banting A et al. | Efficacy of oral and parenteral ketoprofen in lactating cows with endotoxin-induced acute mastitis. | 2008 | Vet. Rec. | pmid:18953074 |
| Csányi G et al. | Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis. | 2008 May-Jun | Pharmacol Rep | pmid:18622059 |
| Capodanno D and Angiolillo DJ | Platelet monitoring for PCI: which test is the one to choose? | 2009 | Hamostaseologie | pmid:19882078 |
| Gao XR et al. | Efficacy of different doses of aspirin in decreasing blood levels of inflammatory markers in patients with cardiovascular metabolic syndrome. | 2009 | J. Pharm. Pharmacol. | pmid:19903376 |
| Zuo Y et al. | Gross-total hematoma removal of hypertensive basal ganglia hemorrhages: a long-term follow-up. | 2009 | J. Neurol. Sci. | pmid:19801153 |
| Frelinger AL et al. | Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization. | 2009 | Circulation | pmid:19996015 |
| Kambara T et al. | Propofol suppresses prostaglandin E(2) production in human peripheral monocytes. | 2009 | Immunopharmacol Immunotoxicol | pmid:19951072 |
| Guerrero MD et al. | Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression. | 2009 | Eur. J. Pharmacol. | pmid:19686718 |
| Hu Y et al. | Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells. | 2009 | Immunopharmacol Immunotoxicol | pmid:19874221 |
| Dietrich-Muszalska A and Olas B | Isoprostenes as indicators of oxidative stress in schizophrenia. | 2009 | World J. Biol. Psychiatry | pmid:19673085 |
| Lowe FJ et al. | Evaluation of biomarkers of exposure and potential harm in smokers, former smokers and never-smokers. | 2009 | Clin. Chem. Lab. Med. | pmid:19676143 |
| Stanke-Labesque F et al. | Increased urinary leukotriene E4 excretion in obstructive sleep apnea: effects of obesity and hypoxia. | 2009 | J. Allergy Clin. Immunol. | pmid:19596146 |
| Li M et al. | Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors. | 2009 | J. Vasc. Res. | pmid:19571576 |
| McClelland S et al. | Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse. | 2009 | Atherosclerosis | pmid:18514659 |
| Coates AM et al. | Regular consumption of n-3 fatty acid-enriched pork modifies cardiovascular risk factors. | 2009 | Br. J. Nutr. | pmid:18590592 |
| Huntjens DR et al. | Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors. | 2009 | Eur J Pain | pmid:18774319 |
| Correa JA et al. | Virgin olive oil polyphenol hydroxytyrosol acetate inhibits in vitro platelet aggregation in human whole blood: comparison with hydroxytyrosol and acetylsalicylic acid. | 2009 | Br. J. Nutr. | pmid:18775097 |
| Hynninen VV et al. | Oral voriconazole and miconazole oral gel produce comparable effects on the pharmacokinetics and pharmacodynamics of etoricoxib. | 2009 | Eur. J. Clin. Pharmacol. | pmid:18777173 |
| Muir AR et al. | Assessment of aspirin resistance varies on a temporal basis in patients with ischaemic heart disease. | 2009 | Heart | pmid:18697805 |
| Xu Y et al. | Urocortin promotes the development of vasculitis in a rat model of thromboangiitis obliterans via corticotrophin-releasing factor type 1 receptors. | 2009 | Br. J. Pharmacol. | pmid:19572944 |
| Foudi N et al. | Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation. | 2009 | Cardiovasc. Res. | pmid:18952694 |
| Rogers LK et al. | Differential responses in the lungs of newborn mouse pups exposed to 85% or >95% oxygen. | 2009 | Pediatr. Res. | pmid:18703992 |
| Zhao L et al. | Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor. | 2009 | Br. J. Pharmacol. | pmid:19220291 |
| Fernández-Arche A et al. | Long-chain fatty alcohols from pomace olive oil modulate the release of proinflammatory mediators. | 2009 | J. Nutr. Biochem. | pmid:18555679 |
| Shah KB et al. | The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling. | 2009 | Hypertension | pmid:19597033 |
| Ulbrich SE et al. | Quantitative characterization of prostaglandins in the uterus of early pregnant cattle. | 2009 | Reproduction | pmid:19470711 |
| Zeng HH et al. | [Effect of safflower injection on pulmonary hypertension in rat during chronic hypoxia and hypercapnia]. | 2009 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:21186611 |
| Santilli F et al. | Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance". | 2009 | J. Am. Coll. Cardiol. | pmid:19232899 |
| Lev EI | Aspirin resistance transient laboratory finding or important clinical entity? | 2009 | J. Am. Coll. Cardiol. | pmid:19232900 |
| Bernoud-Hubac N et al. | Low concentrations of reactive gamma-ketoaldehydes prime thromboxane-dependent human platelet aggregation via p38-MAPK activation. | 2009 | Biochim. Biophys. Acta | pmid:19233311 |
| Giraudel JM et al. | Differential inhibition of cyclooxygenase isoenzymes in the cat by the NSAID robenacoxib. | 2009 | J. Vet. Pharmacol. Ther. | pmid:19161453 |
| Jespersen B et al. | Differential effects of immunosuppressive drugs on COX-2 activity in vitro and in kidney transplant patients in vivo. | 2009 | Nephrol. Dial. Transplant. | pmid:19193738 |
| Chen SS et al. | Elevated plasma prostaglandins and acetylated histone in monocytes in Type 1 diabetes patients. | 2009 | Diabet. Med. | pmid:19236624 |
| Kanazawa S et al. | Effect of low-dose aspirin for skin rash associated with erlotinib therapy in patients with lung cancer. | 2009 | Platelets | pmid:19172526 |
| Calapai G et al. | Cardiovascular biomarkers in groups of established smokers after a decade of smoking. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19175368 |
| Kapetanovic IM et al. | Comparison of pharmacokinetic and pharmacodynamic profiles of aspirin following oral gavage and diet dosing in rats. | 2009 | Chem. Biol. Interact. | pmid:18992230 |
| Seta F et al. | Renal and cardiovascular characterization of COX-2 knockdown mice. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19357295 |
| Pettinella C et al. | Cyclooxygenase-1 haplotype C50T/A-842G does not affect platelet response to aspirin. | 2009 | Thromb. Haemost. | pmid:19350112 |
| Basselin M et al. | Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice. | 2009 | Neuropsychopharmacology | pmid:19145225 |
| Guagnano MT et al. | Determinants of platelet activation in hypertensives with microalbuminuria. | 2009 | Free Radic. Biol. Med. | pmid:19280705 |
| Lo HM et al. | 2'-Ethoxy-5'-methoxy-2-(5-methylthienyl)chalcone inhibits collagen-induced protein tyrosine phosphorylation and thromboxane formation during platelet aggregation and adhesion. | 2009 | Pharmacology | pmid:19690443 |
| Struthmann L et al. | Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo. | 2009 | J. Thromb. Haemost. | pmid:19691487 |
| Omura Y et al. | Severe asthma with markedly increased asbestos of 2 types & TXB2, and markedly reduced acetylcholine, DHEA & drug uptake in parts of upper lungs, & similar abnormalities at respiratory & cardiac center of medulla oblongata: complete elimination of this asthma within 15 days using one optimal dose of astragalus & application of strong red light & EMF neutralizer on respiratory centers of abnormal medulla oblongata. | 2009 | Acupunct Electrother Res | pmid:19711774 |
| Sobotková A et al. | Antioxidants change platelet responses to various stimulating events. | 2009 | Free Radic. Biol. Med. | pmid:19766712 |
| Shen H et al. | Aspirin Resistance in healthy drug-naive men versus women (from the Heredity and Phenotype Intervention Heart Study). | 2009 | Am. J. Cardiol. | pmid:19660620 |
| Leoncini G et al. | In retinal vein occlusion platelet response to thrombin is increased. | 2009 | Thromb. Res. | pmid:19660790 |
| Canales A et al. | Platelet aggregation, eicosanoid production and thrombogenic ratio in individuals at high cardiovascular risk consuming meat enriched in walnut paste. A crossover, placebo-controlled study. | 2009 | Br. J. Nutr. | pmid:19068151 |
| Duda MK et al. | Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction. | 2009 | Cardiovasc. Res. | pmid:19015135 |
| Hynninen VV et al. | Voriconazole increases while itraconazole decreases plasma meloxicam concentrations. | 2009 | Antimicrob. Agents Chemother. | pmid:19015346 |
| Kerola M et al. | Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19152549 |
| Lauring B et al. | Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects. | 2009 | J Clin Pharmacol | pmid:19833861 |
| O'Donnell ME et al. | The effects of cilostazol on exercise-induced ischaemia-reperfusion injury in patients with peripheral arterial disease. | 2009 | Eur J Vasc Endovasc Surg | pmid:19112032 |
| Bailey SR et al. | Plasma concentrations of endotoxin and platelet activation in the developmental stage of oligofructose-induced laminitis. | 2009 | Vet. Immunol. Immunopathol. | pmid:19091426 |
| Dołegowska B et al. | Platelets arachidonic acid metabolism in patients with essential hypertension. | 2009 | Platelets | pmid:19440924 |
| Ahmad M et al. | Prolonged opportunity for neuroprotection in experimental stroke with selective blockade of cyclooxygenase-2 activity. | 2009 | Brain Res. | pmid:19446533 |
| Mayer K et al. | Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids. | 2009 | Am. J. Respir. Crit. Care Med. | pmid:19136374 |
| Schuijt MP et al. | The interaction of ibuprofen and diclofenac with aspirin in healthy volunteers. | 2009 | Br. J. Pharmacol. | pmid:19466986 |
| Eriksson AC et al. | Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study. | 2009 | J Transl Med | pmid:19508722 |
| Cattaneo M | Letter by cattaneo regarding article, "incomplete inhibition of thromboxane biosynthesis by acetylsalicylic Acid: determinants and effect on cardiovascular risk". | 2009 | Circulation | pmid:19546394 |
| Schiff M et al. | Platelet inhibitory effects of OTC doses of naproxen sodium compared with prescription dose naproxen sodium and low-dose aspirin. | 2009 | Curr Med Res Opin | pmid:19678751 |
| Cook VL et al. | Effect of firocoxib or flunixin meglumine on recovery of ischemic-injured equine jejunum. | 2009 | Am. J. Vet. Res. | pmid:19645580 |
| Blais N et al. | Response to aspirin in healthy individuals. Cross-comparison of light transmission aggregometry, VerifyNow system, platelet count drop, thromboelastography (TEG) and urinary 11-dehydrothromboxane B(2). | 2009 | Thromb. Haemost. | pmid:19652893 |
| Zhang X et al. | Effect of baicalin on inflammatory mediator levels and microcirculation disturbance in rats with severe acute pancreatitis. | 2009 | Pancreas | pmid:19657312 |
| Liu FC et al. | A new insight of anti-platelet effects of sirtinol in platelets aggregation via cyclic AMP phosphodiesterase. | 2009 | Biochem. Pharmacol. | pmid:19426675 |
| Li L et al. | The anti-inflammatory effects of ZLJ-6, a novel dual cyclooxygenase/5-lipoxygenase inhibitor. | 2009 | Eur. J. Pharmacol. | pmid:19243697 |
| Peng CY et al. | Dietary soy protein selectively reduces renal prostanoids and cyclooxygenases in polycystic kidney disease. | 2009 | Exp. Biol. Med. (Maywood) | pmid:19429858 |
| Li H et al. | [Effect of an integrative medical regimen on levels of vascular endothelial function and hypersensitive C-reactive protein in elderly patients with isolated systolic hypertension]. | 2009 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:19382469 |
| Goodman L et al. | Effects of firocoxib and tepoxalin on healing in a canine gastric mucosal injury model. | 2009 Jan-Feb | J. Vet. Intern. Med. | pmid:19175721 |