| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vassar MJ et al. | Measurement of 6-keto-PGF1 alpha and thromboxane B2 levels in critically ill surgical patients. | 1988 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:3174719 |
| Bell JG et al. | Dietary sunflower, linseed and fish oils affect phospholipid fatty acid composition, development of cardiac lesions, phospholipase activity and eicosanoid production in Atlantic salmon (Salmo salar). | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8248271 |
| Arruzazabala ML et al. | Effect of policosanol on cerebral ischemia in Mongolian gerbils: role of prostacyclin and thromboxane A2. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8248276 |
| Molina V et al. | Synergistic effect of D-003 and aspirin on experimental thrombosis models. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12711246 |
| Navrátil L et al. | Changes of 6-keto PGF1 alpha concentration in plasma and vessel wall and TxB2 in plasma of whole-body irradiated rats in the early stage of irradiation. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2251295 |
| Dogné JM et al. | Pharmacological evaluation of the novel thromboxane modulator BM-567 (I/II). Effects of BM-567 on platelet function. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12538090 |
| Myers SI et al. | Estrogen increases male rat aortic endothelial cell (RAEC) PGI2 release. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8888351 |
| Mikhailidis DP et al. | Platelet aggregation and thromboxane A2 release in primary biliary cirrhosis and effect of D-penicillamine treatment. | 1988 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:3375287 |
| Agnoli GC et al. | Volume-induced natriuresis in healthy women: renal metabolism of prostacyclin and thromboxane, and physiological role of prostanoids. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11237476 |
| Bagchi D et al. | Enhanced prostaglandin production in the ischemic-reperfused myocardium by captopril linked with its free radical scavenging action. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2694179 |
| Beitz A et al. | Lipoproteins from normolipidemic and dyslipidemic subjects modify the thromboxane A2 generation by platelets in clotting human blood. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8341726 |
| Pascual J et al. | TXB2: cardiostimulant effect that involves beta-adrenoceptor and Na+ + K+-ATPase activity. | 1988 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2847200 |
| Beitz A et al. | Influence of iloprost on eicosanoid generation and lipid levels in experimental myocardial ischemia in dogs. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2469084 |
| Zaitsu M et al. | Induction of thromboxane A2 synthesizing enzymes in DMSO-induced granulocytic differentiation of HL-60 cells. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12468261 |
| Thomson M et al. | The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12468270 |
| Wolfram R et al. | Daily prickly pear consumption improves platelet function. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12878452 |
| Urquhart P et al. | Profile of eicosanoids produced by human saphenous vein endothelial cells and the effect of dietary fatty acids. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11487303 |
| Agnoli GC et al. | Renal function and urinary prostanoid excretions in salt-depleted women: comparative effects of enalapril and indomethacin treatments. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10328327 |
| Chahine R et al. | The anti-thromboxane A2 synthetase activity of myocardial tissue and its variation during ischemia and reperfusion in isolated rabbit heart. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10328329 |
| Peredo HA and Filinger EJ | Effect of dipyridamole on prostanoid production in rat isolated atria. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10328333 |
| Srivastava KC | Effect of onion and ginger consumption on platelet thromboxane production in humans. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2710801 |
| Hammerman C et al. | Lipoxygenase and cyclooxygenase blockade by BW755C does not prevent the secondary phase of septic pulmonary hypertension. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2506581 |
| Schonwetter DJ et al. | Type A behavior and alcohol consumption: effects on resting and post-exercise bleeding time thromboxane and prostacyclin metabolites. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8446651 |
| Ferretti A et al. | Ingestion of marine oil reduces excretion of 11-dehydrothromboxane B2, an index of intravascular production of thromboxane A2. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8497491 |
| Devi MM and Das UN | Effect of prostaglandins against alloxan-induced cytotoxicity to insulin secreting insulinoma RIN cells in vitro. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15380818 |
| Isenring P et al. | Eicosanoid modulation of the norepinephrine effect on blood pressure and renal hemodynamics in humans. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8992495 |
| Singer P and Wirth M | Can n-3 PUFA reduce cardiac arrhythmias? Results of a clinical trial. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15253884 |
| Leung S et al. | Isolation and purification of anticardiolipin antibody from plasma of a patient with antiphospholipid syndrome: induced generation of platelet thromboxane A2 synthesis. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9014216 |
| González E et al. | Nitric oxide modulates placental prostanoid production from late pregnant non-insulin-dependent diabetic rat. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9888203 |
| Stichtenoth DO et al. | Effects of intravenous oxygen on prostacyclin and thromboxane formation in patients with peripheral occlusive arterial disease. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728174 |
| Anfossi G et al. | Effects of diltiazem on thromboxane B2 production from platelet-rich plasma and whole blood. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1808624 |
| Lueddeckens G et al. | Importance of secondary TXA2 release in mediating of endothelin-1 induced bronchoconstriction and vasopressin in the guinea-pig. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8469685 |
| Thomson M et al. | Thromboxane-B(2) levels in serum of rabbits receiving a single intravenous dose of aqueous extract of garlic and onion. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11049697 |
| Ono Y et al. | Improvement in blood flow and diabetic neuropathy by thromboxane A2 dual blocker KDI-792. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7480076 |
| Ali M and Thomson M | Consumption of a garlic clove a day could be beneficial in preventing thrombosis. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7480084 |
| Myers SI et al. | Acute burn down regulates rabbit splanchnic and renal prostanoid release. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7480086 |
| Yamanobe S et al. | Analysis of urinary 11-dehydrothromboxane B2 in patients with occluded retinal vein using GC/SIM. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9482168 |
| Hishinuma T et al. | Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728171 |
| Darlametsos IE et al. | Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: roles of the thromboxane and endothelin systems. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090252 |
| Anfossi G et al. | Influence of propranolol on platelet aggregation and thromboxane B2 production from platelet-rich plasma and whole blood. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2525784 |
| Peeters FA et al. | Thromboxane and prostacyclin production in the perfused rabbit lung. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1946551 |
| Chang WC and Hsu FL | Inhibition of platelet activation and endothelial cell injury by flavan-3-ol and saikosaponin compounds. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1946562 |
| Gurbel PA et al. | Plasma thromboxane and prostacyclin are linear related and increased in patients presenting with acute myocardial infarction. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10477035 |
| Srivastava KC | Extracts from two frequently consumed spices--cumin (Cuminum cyminum) and turmeric (Curcuma longa)--inhibit platelet aggregation and alter eicosanoid biosynthesis in human blood platelets. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2503839 |
| Peredo HA et al. | Prostanoid production in hypoxic rat isolated atria: influence of acute diabetes. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7846089 |
| Neuer A et al. | The effect of zearalenone and 17 beta-estradiol on prostacyclin and thromboxane production in cell cultures from human umbilical cord veins. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7846091 |
| Norman JF and Miller CW | Prostacyclin, thromboxane A2, and atherosclerosis in young hypercholesterolemic swine. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7846098 |
| Brunkwall JS et al. | Papaverine effects on PGI2 and TXA2 release from the canine vascular wall. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1508951 |
| Arnold JH et al. | Production of platelet thromboxane A2 and arterial prostacyclin I2 from hypercholesterolemic rats. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1508954 |
| Hammerman C et al. | Prostanoid inhibition and group B hemolytic streptococci (GBS) induced neutropenia in newborn piglets. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2125731 |
| Mest HJ et al. | Relevance of mediators to cardiac parameters of isolated anaphylactic guinea-pig heart. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7545818 |
| Molina V et al. | D-003, a potential antithrombotic compound isolated from sugar cane wax with effects on arachidonic acid metabolites. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12213431 |
| Gajdos M et al. | Effective long-term inhibition of thromboxane production but not of serotonin release in patients with coronary heart disease by 30 mg/d acetylsalicylic acid dosage. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9758203 |
| Gomi T et al. | Effects of OKY-046, a selective thromboxane synthetase inhibitor, on blood pressure and thromboxane synthesis in spontaneously hypertensive rats. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2608692 |
| Sanigorski AJ et al. | n-3 fatty acids reduce in vitro thromboxane production while having little effect on in vitro prostacyclin production in the rat. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8066095 |
| Srivastava KC and Malhotra N | Acetyl eugenol, a component of oil of cloves (Syzygium aromaticum L.) inhibits aggregation and alters arachidonic acid metabolism in human blood platelets. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2011614 |
| Greer IA et al. | Inhibition of thromboxane and prostacyclin production in whole blood by adrenoceptor antagonists. | 1985 | Prostaglandins Leukot Med | pmid:2865745 |
| Mäkilä UM et al. | Regulation of prostacyclin and thromboxane production by human umbilical vessels: the effect of estradiol and progesterone in a superfusion model. | 1982 | Prostaglandins Leukot Med | pmid:7043492 |
| Durante W and Sunahara FA | Cardiovascular effects of high frequency ventilation--the possible involvement of thromboxane. | 1987 | Prostaglandins Leukot Med | pmid:3114767 |
| Hamasaki Y et al. | Hypoxia stimulates prostacyclin generation by dog lung in vitro. | 1982 | Prostaglandins Leukot Med | pmid:7051045 |
| Merola AJ et al. | Prostaglandin response in the exercise conditioned rat. | 1984 | Prostaglandins Leukot Med | pmid:6377328 |
| Ali M and Mohammed SY | Selective suppression of platelet thromboxane formation with sparing of vascular prostacyclin synthesis by aqueous extract of garlic in rabbits. | 1986 | Prostaglandins Leukot Med | pmid:3547414 |
| Puustinen T et al. | Glucocorticoids do not decrease thromboxane and prostacyclin levels in human blood. | 1984 | Prostaglandins Leukot Med | pmid:6387721 |
| Sinzinger H et al. | Platelet function and prostaglandins in patients with peripheral vascular disease treated with calcium dobesilate. | 1987 | Prostaglandins Leukot Med | pmid:2959967 |
| de Kergommeaux BD et al. | Effects of ASA on thromboxane and prostacyclin synthesis by rabbit aorta and pulmonary artery. | 1983 | Prostaglandins Leukot Med | pmid:6410417 |
| Reeves WC et al. | The release of thromboxane A2 and prostacyclin following experimental acute pulmonary embolism. | 1983 | Prostaglandins Leukot Med | pmid:6348800 |
| Mehta P et al. | Thromboxane and prostacyclin generation by intact human vessels in response to balloon catheter trauma. | 1982 | Prostaglandins Leukot Med | pmid:6217465 |
| Kaar ML et al. | Prostacyclin and thromboxane in diabetic children. | 1983 | Prostaglandins Leukot Med | pmid:6351104 |
| Mehta J et al. | Stimulation of vessel wall prostacyclin by selective thromboxane synthetase inhibitor OKY 1581. | 1983 | Prostaglandins Leukot Med | pmid:6356153 |
| Bucchi F et al. | Salicylate may prevent the inhibitory effect of indomethacin on serum thromboxane formation in man. | 1986 | Prostaglandins Leukot Med | pmid:3456617 |
| Ishihara Y et al. | Effect of thromboxane synthetase inhibitors (OKY-046, OKY-1580) on experimentally induced air embolism in anesthetized dogs. | 1986 | Prostaglandins Leukot Med | pmid:3457388 |
| Kääpä P et al. | Increased platelet thromboxane B2 production in newborn infants of diabetic mothers. | 1986 | Prostaglandins Leukot Med | pmid:3458263 |
| Mitchell JA et al. | Effects of high frequency oscillatory ventilation compared to conventional ventilation upon pulmonary vascular prostanoid production in neonatal piglets. | 1985 | Prostaglandins Leukot Med | pmid:3883366 |
| Tremoli E et al. | In vitro effects of aspirin and non steroidal anti-inflammatory drugs on the formation of 12-hydroxyeicosatetraenoic acid by platelets. | 1986 | Prostaglandins Leukot Med | pmid:3094026 |
| McDonald JW and Ali M | Recovery of cyclooxygenase activity after aspirin in populations of platelets separated on stractan density gradients. | 1983 | Prostaglandins Leukot Med | pmid:6419234 |
| Morita I et al. | Effect of dietary protein level on platelet aggregation in rat. | 1985 | Prostaglandins Leukot Med | pmid:3892545 |
| Punnonen R et al. | Effect of ovariectomy in humans on serum 6-keto-PGF1 alpha and TXB2 concentrations and platelet fatty acids. | 1987 | Prostaglandins Leukot Med | pmid:3468524 |
| Lucas J et al. | Antiarrhythmic agents inhibit the in vitro formation of thromboxane (TX) in platelets from spontaneously hypertensive rats (SHR). | 1987 | Prostaglandins Leukot Med | pmid:3470812 |
| Ali M and Afzal M | A potent inhibitor of thrombin stimulated platelet thromboxane formation from unprocessed tea. | 1987 | Prostaglandins Leukot Med | pmid:3473509 |
| Simberg N | Maternal aspirin administration inhibits pulmonary arachidonic acid metabolism in fetal rabbits. | 1984 | Prostaglandins Leukot Med | pmid:6425868 |
| Rao GH et al. | Enteric-coated aspirin, platelet cyclooxygenase activity and function. | 1984 | Prostaglandins Leukot Med | pmid:6425869 |
| Ouwendijk RJ et al. | Raised plasma thromboxane B2 levels in alcoholic liver disease. | 1983 | Prostaglandins Leukot Med | pmid:6573682 |
| Hornych A et al. | Thromboxane B2 in borderline and essential hypertensive patients. | 1983 | Prostaglandins Leukot Med | pmid:6573683 |
| Flynn JT et al. | Effects of anesthesia and surgery on prostanoid concentrations in plasma and pulmonary lymph. | 1983 | Prostaglandins Leukot Med | pmid:6573688 |
| Patel K and Bakhle YS | Thromboxane B2 (TxB2) metabolism in rat isolated lung and its inhibition by drugs. | 1983 | Prostaglandins Leukot Med | pmid:6573689 |
| Davì G et al. | Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients. | 1983 | Prostaglandins Leukot Med | pmid:6573692 |
| Lieb J et al. | Elevated levels of prostaglandin E2 and thromboxane B2 in depression. | 1983 | Prostaglandins Leukot Med | pmid:6574523 |
| Valentovic MA and Lubawy WC | Elevated glucose in vivo and in vitro adversely alters prostaglandin generation in rat aortas and platelets. | 1985 | Prostaglandins Leukot Med | pmid:3903777 |
| Viinikka L et al. | Effect of prolonged treatment with acetylsalicylic acid and dipyridamole on platelet thromboxane A2 production in atherosclerotic subjects. | 1983 | Prostaglandins Leukot Med | pmid:6576385 |
| Fukumoto S and Tanaka K | Protective effects of thromboxane A2 synthetase inhibitors on endotoxin shock. | 1983 | Prostaglandins Leukot Med | pmid:6576388 |
| Kinney EL et al. | Mechanism of action of amrinone: role of thromboxane synthetase inhibition. | 1983 | Prostaglandins Leukot Med | pmid:6576389 |
| Zijlstra FJ et al. | Separation of the two components of the contractile activity of leukotriene C4 on the guinea pig lung parenchymal strip. | 1983 | Prostaglandins Leukot Med | pmid:6578519 |
| Mahoney DP et al. | Radioimmunoassay of prostaglandins and thromboxane B2 in extracted and unextracted urine and serum using an iodinated ligand. | 1983 | Prostaglandins Leukot Med | pmid:6579570 |
| Güllner HG et al. | Renal thromboxane excretion in Brattleboro rats with hereditary hypothalamic diabetes insipidus. Effect of vasopressin treatment. | 1983 | Prostaglandins Leukot Med | pmid:6580653 |
| Orlandi M et al. | Normal plasma thromboxane B2 (TXB2) and 6-keto-PGF1 alpha levels in childhood diabetes. | 1983 | Prostaglandins Leukot Med | pmid:6583712 |
| Männistö J and Uotila P | Cigarette smoke ventilation decreases thromboxane B2 metabolism in isolated rat lungs. | 1983 | Prostaglandins Leukot Med | pmid:6583713 |
| Dahl ML and Uotila P | Sodium salicylate does not prevent the inhibitory effect of indomethacin on thromboxane formation in human blood ex vivo. | 1985 | Prostaglandins Leukot Med | pmid:3856282 |
| Kääpä P | Immunoreactive thromboxane B2 and 6-keto-prostaglandin F1 alpha in neonatal hyperbilirubinemia. | 1985 | Prostaglandins Leukot Med | pmid:3856285 |
| Zijlstra FJ and Vincent JE | Leukotriene D4 and phospholipase A2 release thromboxane A2 of different origin in the guinea pig lung parenchymal strip. | 1985 | Prostaglandins Leukot Med | pmid:3857642 |
| Pohanka E and Sinzinger H | Effect of a single pentoxifylline administration on platelet sensitivity, plasma factor activity, plasma-6-oxo-PGF1 alpha and thromboxane B2 in healthy volunteers. | 1986 | Prostaglandins Leukot Med | pmid:3523540 |