Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Oligomenorrhea D009839 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Bluetongue D001819 1 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
Foot Rot D005535 1 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Schuligoi R et al. Effects of the cyclooxygenase-2 inhibitor NS-398 on thromboxane and leukotriene synthesis in rat peritoneal cells. 1998 Inflamm. Res. pmid:9657255
Takeuchi K et al. Development of dual-acting agents for thromboxane receptor antagonism and thromboxane synthase inhibition. 3. Synthesis and biological activities of oxazolecarboxamide-substituted omega-phenyl-omega-(3-pyridyl)alkenoic acid derivatives and related compounds. 1998 J. Med. Chem. pmid:9876106
Mayser P et al. Omega-3 fatty acid-based lipid infusion in patients with chronic plaque psoriasis: results of a double-blind, randomized, placebo-controlled, multicenter trial. 1998 J. Am. Acad. Dermatol. pmid:9555791
Shen ZQ et al. Effects of copper-aspirin complex on platelet aggregation and thrombosis in rabbits and mice. 1998 J. Pharm. Pharmacol. pmid:9877314
Huang YS et al. Serial experimental and clinical studies on the pathogenesis of multiple organ dysfunction syndrome (MODS) in severe burns. 1998 Burns pmid:9915670
Murphy NP et al. Functional relevance of the expression of ligand-induced binding sites in the response to platelet GP IIb/IIIa antagonists in vivo. 1998 J. Pharmacol. Exp. Ther. pmid:9694954
Simon LS et al. Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects. 1998 Arthritis Rheum. pmid:9751091
Thomson M et al. Prostanoid synthesis in whole blood cells from fish of the Arabian Gulf. 1998 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:9787758
Ozyazgan I et al. Eicosanoids and inflammatory cells in frostbitten tissue: prostacyclin, thromboxane, polymorphonuclear leukocytes, and mast cells. 1998 Plast. Reconstr. Surg. pmid:9623831
Cheng Z et al. Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. 1998 Inflammation pmid:9675607
Stephenson AH et al. 5,6-Epoxyeicosatrienoic acid reduces increases in pulmonary vascular resistance in the dog. 1998 Am. J. Physiol. pmid:9688901
Wu Y et al. [Clinical study on improving effect of Buyang Huanwu decoction on plasma thromboxane B2, 6-keto-prostaglandin F1 alpha, endothelin and calcitonin gene related peptide in primary nephrotic syndrome patients]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11475715
Lang J et al. [Comparative study on effect of Panax notoginseng and ticlid in treating early diabetic nephropathy]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11475719
Saitta A et al. Effects of picotamide on release of endothelin-1, thromboxane and prostacycline after treadmill stress in patients with peripheral artery disease. 1998 Angiology pmid:9822043
Lin S et al. [Clinical study on active factors of vascular endothelial cells in acute cerebral infarction patients and therapeutical effect of activating blood stasis]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11477811
Salomon P and Halawa B [Levels of neuropeptide Y and thromboxane B2 in patients with variant angina]. 1998 Pol. Arch. Med. Wewn. pmid:10335040
Huang R et al. [Effects in tetramethylpyrazine on TXA2 and PGI2 by cardio-pulmonary bypass in congenital heart diseases with pulmonary hypertension patients]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11477904
Xu J et al. [Study on relativity between oxygen free radical and thromboxane B2, 6-keto-PGF1 alpha during ligustrazine treatment of intrauterine growth retardation]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11477921
Yang VW et al. Size-dependent increase in prostanoid levels in adenomas of patients with familial adenomatous polyposis. 1998 Cancer Res. pmid:9563494
Diven WF et al. Expression of acute otitis media after receptor blockade of platelet activating factor, thromboxane, and leukotrienes in the chinchilla. 1998 Ann. Otol. Rhinol. Laryngol. pmid:9525240
Lu G et al. [Effect of xueling on relating substances of renal hypertension in rats]. 1998 Zhongguo Zhong Yao Za Zhi pmid:11601304
LaNoue JL et al. Alveolar macrophage response to remote organ injury. 1998 Shock pmid:9565254
Bell JG et al. Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9690713
Darien BJ et al. Low molecular weight heparin prevents the pulmonary hemodynamic and pathomorphologic effects of endotoxin in a porcine acute lung injury model. 1998 Shock pmid:9565256
Muscará MN et al. Effect of a nitric oxide-releasing naproxen derivative on hypertension and gastric damage induced by chronic nitric oxide inhibition in the rat. 1998 Life Sci. pmid:9566780
Davì G et al. Increased thromboxane metabolites excretion in liver cirrhosis. 1998 Thromb. Haemost. pmid:9569186
Chen J et al. [Study on the relationship between the bond absorption of chronic periapical periodontitis and PGE2 and TXB2]. 1998 Zhonghua Kou Qiang Yi Xue Za Zhi pmid:11774418
Kunitoh H et al. A double-blind, placebo-controlled trial of the thromboxane synthetase blocker OKY-046 on bronchial hypersensitivity in bronchial asthma patients. 1998 J Asthma pmid:9669829
Kimura H et al. Compensatory excretion of prostacyclin and thromboxane metabolites in obstructive sleep apnea syndrome. 1998 Intern. Med. pmid:9550591
Miyamoto A et al. The role of thromboxane A2 in regulating porcine basilar arterial tone. 1998 J. Vet. Pharmacol. Ther. pmid:9673964
Saareks V et al. Nicotine stereoisomers and cotinine stimulate prostaglandin E2 but inhibit thromboxane B2 and leukotriene E4 synthesis in whole blood. 1998 Eur. J. Pharmacol. pmid:9721044
Napoli E and Franco N [Thromboxane A2 production in the pathogenesis of diabetic complications]. 1998 Minerva Endocrinol. pmid:9691631
Ali M et al. Urothelial synthesis of prostanoids in the ovine ureter. 1998 Urol. Res. pmid:9694598
Cignarella A et al. Platelet activation supports the development of venous thrombosis in hyperlipidemic rats. 1998 Blood Coagul. Fibrinolysis pmid:9607118
van der Weiden RM et al. Which prostanoid metabolites should be determined for the study of reproductive processes? 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9610843
Beitz A Influence of diet-modified lipoprotein fractions from rabbits on eicosanoid production and on proliferation of rabbit skin fibroblasts. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9610847
Agnoli GC et al. Effects of experimental salt depletion on urinary prostanoid excretions in normal women. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9610848
Stamler A et al. Low-dose dopexamine's effect on lung and gut function after CPB in a sheep model. 1998 J. Surg. Res. pmid:9587356
Franconi F et al. Further insights into the anti-aggregating activity of NMDA in human platelets. 1998 Br. J. Pharmacol. pmid:9630340
Huszár E et al. Elevated circulating adenosine level potentiates antigen-induced immediate bronchospasm and bronchoconstrictor mediator release in sensitized guinea pigs. 1998 J. Allergy Clin. Immunol. pmid:9802380
Vormann J et al. Pathobiochemical effects of graded magnesium deficiency in rats. 1998 Z Ernahrungswiss pmid:9558736
Agostoni C et al. Plasma arachidonic acid and serum thromboxane B2 concentrations in phenylketonuric children are correlated with dietary compliance. 1998 Z Ernahrungswiss pmid:9558743
Zhang T et al. [Clinical observation on preventing and treating coronary atherosclerotic heart disease with tongmai jiangzhi oral liquid]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11367649
Tsai WJ et al. Characterization of the antiplatelet effects of (2S)-5-methoxy-6-methylflavan-7-ol from Draconis Resina. 1998 Eur. J. Pharmacol. pmid:9617759
Yu Y et al. [Changes of prostaglandins in kidney tissue in gentamicin-induced acute renal tubular injury in rats]. 1998 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:11367732
Yamanobe S et al. Analysis of urinary 11-dehydrothromboxane B2 in patients with occluded retinal vein using GC/SIM. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9482168
Kalgutkar AS et al. Aspirin-like molecules that covalently inactivate cyclooxygenase-2. 1998 Science pmid:9596581
Rho MC et al. Two distinct effects of 12S-hydroxyeicosatetraenoic acid on platelet aggregation by zooxanthellatoxin-A and ionomycin. 1998 Jpn. J. Pharmacol. pmid:9517414
Giustina A et al. Long-term treatment with the dual antithromboxane agent picotamide decreases microalbuminuria in normotensive type 2 diabetic patients. 1998 Diabetes pmid:9519749
Bode-Böger SM et al. Differential inhibition of human platelet aggregation and thromboxane A2 formation by L-arginine in vivo and in vitro. 1998 Naunyn Schmiedebergs Arch. Pharmacol. pmid:9521487
Ingster LM and Feinleib M Salicylate intake and cardiovascular disease: Ingster and Feinleib respond to Hu and Willett. 1998 Am J Public Health pmid:9702172
Hsiao G et al. Antiplatelet action of 3',4'-diisovalerylkhellactone diester purified from Peucedanum japonicum Thunb. 1998 Biol. Pharm. Bull. pmid:9703250
Turpeinen AM et al. Replacement of dietary saturated by unsaturated fatty acids: effects of platelet protein kinase C activity, urinary content of 2,3-dinor-TXB2 and in vitro platelet aggregation in healthy man. 1998 Thromb. Haemost. pmid:9798986
Lees P et al. Pharmacodynamics and pharmacokinetics of tolfenamic acid in ruminating calves: evaluation in models of acute inflammation. 1998 Vet. J. pmid:9638074
van Dijk AP et al. Transdermal nicotine inhibits interleukin 2 synthesis by mononuclear cells derived from healthy volunteers. 1998 Eur. J. Clin. Invest. pmid:9767362
Bereczki C et al. Increased platelet thromboxane release in focal segmental glomerulosclerosis. 1998 Nephrol. Dial. Transplant. pmid:9641208
Jokela R et al. Effect of in vitro stability of dietary fish oil on lipid peroxidation and prostanoids in vivo. 1998 Ups. J. Med. Sci. pmid:10052110
Mink SN et al. Effect of bolus epinephrine on systemic hemodynamics in canine anaphylactic shock. 1998 Cardiovasc. Res. pmid:10070496
Lindström T et al. The effect of unreamed and reamed intramedullary nailing on the urinary excretion of prostacyclin and thromboxane A2 metabolites in patients with tibial shaft fractures. 1998 J Trauma pmid:9783614
Cadroy Y et al. Arachidonic acid enhances the tissue factor expression of mononuclear cells by the cyclo-oxygenase-1 pathway: beneficial effect of n-3 fatty acids. 1998 J. Immunol. pmid:9637532
Li G et al. Ischemic preconditioning enhances donor lung preservation in canine lung transplantation. 1998 Chin. Med. J. pmid:11189228
Guo Q et al. [Influence of moderate hypothermia on the contents of 6-KETO-PGF1 alpha and TXB2 in brain tissues after cardiac arrest and resuscitation in dogs]. 1998 Hunan Yi Ke Da Xue Xue Bao pmid:11189396
John H et al. Development and review of radioimmunoassay of 12-S-hydroxyheptadecatrienoic acid. 1998 Prostaglandins Other Lipid Mediat. pmid:9785378
Herrera JA et al. Prevention of preeclampsia by linoleic acid and calcium supplementation: a randomized controlled trial. 1998 Obstet Gynecol pmid:9540946
Lebel B et al. Inhibition of mediator release from dispersed nasal polyp cells by cyclosporin A. 1998 Int. Arch. Allergy Immunol. pmid:9693278
Yan C and Feng Y [Effects of butylphthalide on extracellular 6-keto-PGF1 alpha, TXB2 and 6-keto-PGF1 alpha/TXB2 ratio in cultured rat cortical neurons]. 1998 Yao Xue Xue Bao pmid:12016850
Yu W and Xu L [Effects of acetylsalvianolic acid A on arachidonic acid metabolism in platelets]. 1998 Yao Xue Xue Bao pmid:11938938
Oishi M and Mochizuki Y beta-Thromboglobulin and 11-dehydrothromboxane B in tension-type headache. 1998 Headache pmid:15613179
Gajdos M et al. Effective long-term inhibition of thromboxane production but not of serotonin release in patients with coronary heart disease by 30 mg/d acetylsalicylic acid dosage. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9758203
Onizuka M et al. Suppression of prostanoid formation and regulation of peripheral circulation after surgery using thrombin inhibitor (MD805). 1998 Surg. Today pmid:9681611
De La Cruz JP et al. Effect of camonagrel, a selective thromboxane synthase inhibitor, on retinal vascularization in experimental diabetes. 1998 Eur. J. Pharmacol. pmid:9683018
Tewes KS et al. Measurement of thromboxane B2 in platelet-rich human plasma by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry following extractive pentafluorobenzyl esterification. 1998 Anal. Biochem. pmid:9683522
Hoffmann MW et al. [Long term effects of 50 mg acetylsalicylic acid alone and in combination with dipyridamole on platelet function after coronary bypass surgery]. 1998 Z Kardiol pmid:9885179
Bassiouny HS et al. Low flow enhances platelet activation after acute experimental arterial injury. 1998 J. Vasc. Surg. pmid:9620144
Ricketts AP et al. Evaluation of selective inhibition of canine cyclooxygenase 1 and 2 by carprofen and other nonsteroidal anti-inflammatory drugs. 1998 Am. J. Vet. Res. pmid:9829404
Gust R et al. Synergistic hemodynamic effects of low-dose endotoxin and acute lung injury. 1998 Am. J. Respir. Crit. Care Med. pmid:9620928
Oosaki R et al. Correlation among urinary eosinophil protein X, leukotriene E4, and 11-dehydrothromboxane B2 in patients with spontaneous asthmatic attack. 1998 Clin. Exp. Allergy pmid:9761018
de la Cruz JP et al. Effect of WEB 2086-BS, an antagonist of platelet-activating factor receptors, on retinal vascularity in diabetic rats. 1998 Eur. J. Pharmacol. pmid:9845270
Aoki T et al. Difference of (Ca2+)i movements in platelets stimulated by thrombin and TRAP: the involvement of alpha(IIb)beta3-mediated TXA2 synthesis. 1998 Thromb. Haemost. pmid:9657446
Bode-Böger SM et al. Chronic dietary supplementation with L-arginine inhibits platelet aggregation and thromboxane A2 synthesis in hypercholesterolaemic rabbits in vivo. 1998 Cardiovasc. Res. pmid:9659460
Menè P et al. Eicosanoid synthesis in peripheral blood monocytes: a marker of disease activity in lupus nephritis. 1998 Am. J. Kidney Dis. pmid:9820447
Adler S and Bollu R Glomerular endothelial cell injury mediated by shiga-like toxin-1. 1998 Kidney Blood Press. Res. pmid:9661132
Geertsen PF et al. Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2. 1998 Clin. Sci. pmid:9662488
Schilling MK et al. Role of thromboxane and leukotriene B4 in patients with acute respiratory distress syndrome after oesophagectomy. 1998 Br J Anaesth pmid:9505775
Hauth J et al. Maternal serum thromboxane B2 concentrations do not predict improved outcomes in high-risk pregnancies in a low-dose aspirin trial. The National Institute of Child Health and Human Development Network of Maternal-Fetal Medical Units. 1998 Am. J. Obstet. Gynecol. pmid:9822499
Chen MF et al. Vitamin E supplementation attenuates myointimal proliferation of the abdominal aorta after balloon injury in diet-induced hypercholesterolemic rabbits. 1998 Prostaglandins Other Lipid Mediat. pmid:9777654
Kalgutkar AS et al. Covalent modification of cyclooxygenase-2 (COX-2) by 2-acetoxyphenyl alkyl sulfides, a new class of selective COX-2 inactivators. 1998 J. Med. Chem. pmid:9822550
Schmeck J et al. Endothelin-1 and thromboxane A2 increase pulmonary vascular resistance in granulocyte-mediated lung injury. 1998 Crit. Care Med. pmid:9824081
Nieuwenhuys CM and Hornstra G The effects of purified eicosapentaenoic and docosahexaenoic acids on arterial thrombosis tendency and platelet function in rats. 1998 Biochim. Biophys. Acta pmid:9487152
Praticò D et al. Chronic obstructive pulmonary disease is associated with an increase in urinary levels of isoprostane F2alpha-III, an index of oxidant stress. 1998 Am. J. Respir. Crit. Care Med. pmid:9847257
Swails WS et al. Effect of a fish oil structured lipid-based diet on prostaglandin release from mononuclear cells in cancer patients after surgery. 1997 Sep-Oct JPEN J Parenter Enteral Nutr pmid:9323688
Komarevtseva IA et al. [Change in prostanoid metabolism in cystic kidney lesion]. 1997 Sep-Dec Ukr. Biokhim. Zh. pmid:9606841
Knowles SO and Donaldson WE Lead disrupts eicosanoid metabolism, macrophage function, and disease resistance in birds. 1997 Oct-Nov Biol Trace Elem Res pmid:9404672
Sorem KA and Siler-Khodr TM Effect of IGF-I on placental thromboxane and prostacyclin release in severe intrauterine growth retardation. 1997 Nov-Dec J Matern Fetal Med pmid:9438218
Uteshev DB and Uteshev BS [Adhesive molecules as drugs and objects of pharmacological effect in myocardial ischemia and reperfusion]. 1997 May-Jun Eksp Klin Farmakol pmid:9324410
Ansley DM et al. Platelet activating factor and thromboxane B2 production after cardiopulmonary bypass. 1997 May-Jun J Invest Surg pmid:9219083
Matsumata T et al. Urinary excretion of prostaglandins and renal function after hepatic resection. 1997 May-Jun Hepatogastroenterology pmid:9222688
Tomas-Barberan S et al. Effect of diclofenac on prostaglandin liberation in the rabbit after photorefractive keratectomy. 1997 Mar-Apr J Refract Surg pmid:9109071
Shellhaas CS et al. Intravillous eicosanoid compartmentalization and regulation of placental blood flow. 1997 Mar-Apr J. Soc. Gynecol. Investig. pmid:9101462
Cueto SM et al. beta-Carotene attenuates peroxide-induced vasoconstriction in the human placenta. 1997 Mar-Apr J. Soc. Gynecol. Investig. pmid:9101463