Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Osteoblastoma D018215 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Drowning D004332 2 associated lipids
Jejunal Diseases D007579 3 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Radiculopathy D011843 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
O'Sullivan MG et al. Lipopolysaccharide-induced expression of prostaglandin H synthase-2 in alveolar macrophages is inhibited by dexamethasone but not by aspirin. 1993 Biochem. Biophys. Res. Commun. pmid:8466506
Morris RH and Davies GG Thin layer chromatographic identification of thromboxane B2 in serum, and platelet rich plasma stimulated by arachidonic acid and collagen. 1993 Ann. Clin. Biochem. pmid:8466155
Wang Y et al. Pulmonary hypertensive response to rabbit blood components in goats: role of thromboxane. 1993 Am. Rev. Respir. Dis. pmid:8466129
Matera G et al. Effects of two magainin peptides on eicosanoid release from rat peritoneal macrophages. 1993 Antimicrob. Agents Chemother. pmid:8460910
Chang SW and Ohara N Increased pulmonary vascular permeability in rats with biliary cirrhosis: role of thromboxane A2. 1993 Am. J. Physiol. pmid:8460713
Olson NC et al. Pertussis toxin attenuates platelet-activating factor-induced pulmonary hemodynamic alterations in pigs. 1993 Am. J. Physiol. pmid:8460710
Legnani C et al. Effects of a dried garlic preparation on fibrinolysis and platelet aggregation in healthy subjects. 1993 Arzneimittelforschung pmid:8457236
Moriau M et al. Platelet anti-aggregant and rheological properties of piracetam. A pharmacodynamic study in normal subjects. 1993 Arzneimittelforschung pmid:8457235
Katusić ZS et al. Endothelium-dependent contractions to oxygen-derived free radicals in the canine basilar artery. 1993 Am. J. Physiol. pmid:8456988
Sørensen JD et al. Effects of fish oil supplementation in the third trimester of pregnancy on prostacyclin and thromboxane production. 1993 Am. J. Obstet. Gynecol. pmid:8456902
Canale P et al. Splanchnic artery occlusion shock: vinblastine-induced leukopenia reduces tumour necrosis factor and thromboxane A2 formation, and increases survival rate. 1993 Jan-Feb Pharmacol. Res. pmid:8456059
Szekeres L and Tósaki A Release of 6-keto-PGF1 alpha and thromboxane B2 in late appearing cardioprotection induced by the stable PGI analogue: 7-OXO-PGI. 1993 Mol. Cell. Biochem. pmid:8455575
Nyyssönen K et al. High-performance liquid chromatographic assay of platelet-produced thromboxane B2. 1993 J. Chromatogr. pmid:8454699
Shafique T et al. Cardiopulmonary bypass and pulmonary thromboxane generation. 1993 Ann. Thorac. Surg. pmid:8452438
Chen HI et al. Effects of exercise training on the biosynthesis of prostacyclin and thromboxane in rats. 1993 Acta Physiol. Scand. pmid:8452036
Kearon C and Hirsh J Optimal dose for starting and maintaining low-dose aspirin. 1993 Arch. Intern. Med. pmid:8447706
Del Balzo U et al. Complement C5a-mediated myocardial ischemia and neutrophil sequestration: two independent phenomena. 1993 Am. J. Physiol. pmid:8447449
Schonwetter DJ et al. Type A behavior and alcohol consumption: effects on resting and post-exercise bleeding time thromboxane and prostacyclin metabolites. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8446651
Obata T et al. Inhibitory effect of a peptide leukotriene antagonist ONO-1078 on LTD4- and antigen-induced thromboxane B2 production in guinea pig lungs. 1993 Life Sci. pmid:8445989
Stadler J et al. Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells. 1993 J. Leukoc. Biol. pmid:8445328
Kontessis PS et al. Effect of selective inhibition of thromboxane synthesis on renal function in diabetic nephropathy. 1993 J. Lab. Clin. Med. pmid:8445289
Eades SC Endotoxemia in dairy cattle: role of eicosanoids in reticulorumen stasis. 1993 J. Dairy Sci. pmid:8445095
Hwang DL et al. Insulin increases intracellular magnesium transport in human platelets. 1993 J. Clin. Endocrinol. Metab. pmid:8445010
Chen TY et al. Protective effects of anti-O polysaccharide and anti-lipid A monoclonal antibodies on pulmonary hemodynamics. 1993 J. Appl. Physiol. pmid:8444723
Zamora CA et al. Thromboxane contributes to pulmonary hypertension in ischemia-reperfusion lung injury. 1993 J. Appl. Physiol. pmid:8444695
Westlund P Purification and some properties of 11-hydroxythromboxane B2 dehydrogenase from porcine kidney. 1993 Eur. J. Biochem. pmid:8444177
Mennander A et al. Chronic rejection in rat aortic allografts. IV. Effect of hypercholesterolemia in allograft arteriosclerosis. 1993 Jan-Feb J. Heart Lung Transplant. pmid:8443189
Foulon I et al. Increased in vivo production of thromboxane in patients with sickle cell disease is accompanied by an impairment of platelet functions to the thromboxane A2 agonist U46619. 1993 Arterioscler. Thromb. pmid:8443146
McKinnon KP et al. In vitro ozone exposure increases release of arachidonic acid products from a human bronchial epithelial cell line. 1993 Toxicol. Appl. Pharmacol. pmid:8442000
Weise WJ et al. Fish oil has protective and therapeutic effects on proteinuria in passive Heymann nephritis. 1993 Kidney Int. pmid:8441231
Chelucci GL et al. Aspirin effect on early and late changes in acute lung injury in sheep. 1993 Intensive Care Med pmid:8440792
Häyry P et al. Role of thromboxane in the generation of allograft arteriosclerosis in chronic rejection. 1993 Transplant. Proc. pmid:8438433
Ogletree ML et al. Pharmacological profile of BMS 180,291: a potent, long-acting, orally active thromboxane A2/prostaglandin endoperoxide receptor antagonist. 1993 J. Pharmacol. Exp. Ther. pmid:8437108
Hallbrucker C et al. Hydroperoxide metabolism in rat liver. K+ channel activation, cell volume changes and eicosanoid formation. 1993 Eur. J. Biochem. pmid:8436107
Hansen JB et al. Effects of cod liver oil on lipids and platelets in males and females. 1993 Eur J Clin Nutr pmid:8436090
Waring P et al. The effects of leukaemia inhibitory factor on platelet function. 1993 Br. J. Haematol. pmid:8435339
Adatia I et al. Abnormalities in the biosynthesis of thromboxane A2 and prostacyclin in children with cyanotic congenital heart disease. 1993 Br Heart J pmid:8435245
Cole DJ et al. Brain eicosanoid levels during temporary focal cerebral ischemia in rats: a microdialysis study. 1993 J Neurosurg Anesthesiol pmid:8431669
Huttemeier PC et al. Microdialysis measurements of PGD2, TXB2 and 6-KETO-PGF1 alpha in rat CA1 hippocampus during transient cerebral ischemia. 1993 Prostaglandins pmid:8430228
Hata Y et al. Primary colonic epithelial cell culture of the rabbit producing prostaglandins. 1993 Prostaglandins pmid:8430223
Woods LW et al. Structural and biochemical changes in lungs of 3-methylindole-treated rats. 1993 Am. J. Pathol. pmid:8424451
Blair IA et al. Dietary modification of omega 6 fatty acid intake and its effect on urinary eicosanoid excretion. 1993 Am. J. Clin. Nutr. pmid:8424383
Morin CL et al. Thromboxane production in copper-deficient and marginal platelets: influence of superoxide dismutase and lipid hydroperoxides. 1993 Proc. Soc. Exp. Biol. Med. pmid:8424106
Koudstaal PJ et al. Increased thromboxane biosynthesis in patients with acute cerebral ischemia. 1993 Stroke pmid:8421822
Van Assche FA et al. Increased thromboxane formation in diabetic pregnancy as a possible contributor to preeclampsia. 1993 Am. J. Obstet. Gynecol. pmid:8420355
Schiff E et al. Reduction of thromboxane A2 synthesis in pregnancy by polyunsaturated fatty acid supplements. 1993 Am. J. Obstet. Gynecol. pmid:8420313
Feinberg WM and Bruck DC Effect of oral nimodipine on platelet function. 1993 Stroke pmid:8418530
Taddei S and Vanhoutte PM Role of endothelium in endothelin-evoked contractions in the rat aorta. 1993 Hypertension pmid:8418029
Hashimoto K et al. Perfusion pressure control by adenosine triphosphate given during cardiopulmonary bypass. 1993 Ann. Thorac. Surg. pmid:8417658
Koizumi T et al. Effects of continuous infusion of nitroglycerin on pulmonary hemodynamics, lung lymph balance, and prostanoid products in the response to endotoxin in awake sheep. 1993 Lung pmid:8416417