| MeSH term | MeSH ID | Detail |
|---|---|---|
| Osteoblastoma | D018215 | 1 associated lipids |
| Erythromelalgia | D004916 | 1 associated lipids |
| Fibromuscular Dysplasia | D005352 | 2 associated lipids |
| Atrial Premature Complexes | D018880 | 1 associated lipids |
| Latex Hypersensitivity | D020315 | 1 associated lipids |
| Drowning | D004332 | 2 associated lipids |
| Jejunal Diseases | D007579 | 3 associated lipids |
| Basal Ganglia Hemorrhage | D020145 | 1 associated lipids |
| Radiculopathy | D011843 | 1 associated lipids |
| Intracranial Hemorrhage, Hypertensive | D020299 | 1 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kaehler S et al. | S-ibuprofen effectively inhibits thromboxane B2 levels and platelet function in an experimental model of lipopolysaccharide-stimulated and non-stimulated whole blood. | 2008 | Pharmacology | pmid:18043009 |
| Cheng WW and Zhang ZJ | [Low-dose aspirin preventing pregnancy induced hypertension]. | 1991 | Zhonghua Fu Chan Ke Za Zhi | pmid:1804603 |
| Marvin CC et al. | Synthesis of thromboxane B2 via ketalization/ring-closing metathesis. | 2007 | Org. Lett. | pmid:18047355 |
| Tan JQ et al. | [Effects of trilobine on platelet aggregation, thromboxane A2, and prostacyclin formation in rats]. | 1991 | Zhongguo Yao Li Xue Bao | pmid:1807088 |
| Anfossi G et al. | Effects of diltiazem on thromboxane B2 production from platelet-rich plasma and whole blood. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1808624 |
| Lueddeckens G et al. | Influence of aminophylline and ketotifen in comparison to the lipoxygenase inhibitors NDGA and esculetin and the PAF antagonists WEB 2170 [correction of 2107] and BN 52021 on endothelin-1 induced vaso- and bronchoconstriction. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1808625 |
| Hasan J et al. | Early postnatal ibuprofen and indomethacin effects in suckling and weanling rat kidneys. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18096423 |
| Kawakage M et al. | Beneficial effect of the novel thromboxane A2 receptor antagonist sodium (E)-11-[2-(5,6-dimethyl-1-benzimidazolyl)ethylidene]-6,11- dihydrodibenz[b,e]oxepine-2-carboxylate monohydrate on collagen-induced coronary ischemia in guinea-pigs. | 1991 | Arzneimittelforschung | pmid:1815524 |
| Graff J et al. | Significant effects of tipranavir on platelet aggregation and thromboxane B2 formation in vitro and in vivo. | 2008 | J. Antimicrob. Chemother. | pmid:18156609 |
| Wang Z et al. | Changes of vasoactive polypeptides during postoperative hypertensive crisis in patients with hypertensive intracerebral hemorrhage. | 2007 | Chin. Med. J. | pmid:18167188 |
| Mitomori T et al. | [Three infants with severe myocardial ischemia diagnosed by echocardiography: investigation of the cause of transient myocardial dysfunction]. | 1991 | J Cardiol | pmid:1817178 |
| Sun B | [An experimental research on the acute lung injury induced by endotoxin]. | 1991 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:1818775 |
| Magagna A et al. | Indomethacin raises blood pressure in untreated essential hypertensives: a double-blind randomly allocated study versus placebo. | 1991 | J Hypertens Suppl | pmid:1818960 |
| Kaneko I et al. | Prostaglandin F(2alpha) regulates cytokine responses of mast cells through the receptors for prostaglandin E. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18190789 |
| Lin ZX et al. | [Relation between malondialdehyde generation by platelets and plasma thromboxane B2 and diagnostic classification by syndrome differentiation of traditional Chinese medicine in stroke during acute stage]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:1821334 |
| Wang L | [Effect of captopril on urinary 6-keto-PGF1 alpha, thromboxane B2 in inbred SHR rats]. | 1991 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:1821358 |
| Aslam R et al. | Lipoproteins inhibit platelet aggregation and arachidonic acid metabolism in experimental hypercholesterolaemia. | 2008 | Clin. Exp. Pharmacol. Physiol. | pmid:18215184 |
| Huang CG et al. | [Effects of berberine on synthesis of platelet TXA2 and plasma PGI2 in rabbits]. | 1991 | Zhongguo Yao Li Xue Bao | pmid:1824005 |
| Lu H et al. | Temperature dependence of plasmin-induced activation or inhibition of human platelets. | 1991 | Blood | pmid:1825290 |
| Lumley P et al. | Maximal blockade of TxA2 without compromised PGI2 formation; a superior profile of the TxA2 receptor blocking drug GR32191 over aspirin. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1825385 |
| Patrono C et al. | Thromboxane-dependent platelet activation as a transducer of enhanced risk of coronary and cerebral thrombosis. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1825389 |
| Zhao Y et al. | Thromboxane and leukotriene generation by mononuclearcytes from cardiac transplant patients. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1825392 |
| Vial JH et al. | Rebound elevation in urinary thromboxane B2 and 6-keto-PGF1 alpha excretion after aspirin withdrawal. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1825534 |
| Ritter JM et al. | On the mechanism of the prolonged action in man of GR32191, a thromboxane receptor antagonist. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1825568 |
| Delgado-Lista J et al. | Chronic dietary fat intake modifies the postprandial response of hemostatic markers to a single fatty test meal. | 2008 | Am. J. Clin. Nutr. | pmid:18258620 |
| Seeger W et al. | Lung vascular injury after administration of viable hemolysin-forming Escherichia coli in isolated rabbit lungs. | 1991 | Am. Rev. Respir. Dis. | pmid:1826193 |
| O-hara M et al. | Eicosapentanoic acid suppresses intimal hyperplasia after expanded polytetrafluoroethylene grafting in rabbits fed a high cholesterol diet. | 1991 | J. Vasc. Surg. | pmid:1826332 |
| Storch J and MacDermot J | IgE and IgG are synergistic in antigen-mediated release of thromboxane from human lung macrophages. | 1991 | Cell. Immunol. | pmid:1826465 |
| Salonen JT et al. | Effects of antioxidant supplementation on platelet function: a randomized pair-matched, placebo-controlled, double-blind trial in men with low antioxidant status. | 1991 | Am. J. Clin. Nutr. | pmid:1826987 |
| Fitscha P et al. | Effects of isradipine on platelet function in hypertension at rest and during exercise. | 1991 | Am. J. Hypertens. | pmid:1827015 |
| Park JW et al. | 15,16-dihydrotanshinone I, a major component from Salvia miltiorrhiza Bunge (Dansham), inhibits rabbit platelet aggregation by suppressing intracellular calcium mobilization. | 2008 | Arch. Pharm. Res. | pmid:18277607 |
| Tóth L et al. | [Plasma and urine beta-thromboglobulin determination in the detection of thrombocyte hyperactivation in diabetic nephropathies]. | 1991 | Orv Hetil | pmid:1828563 |
| Geske FJ et al. | AspirinWorks: a new immunologic diagnostic test for monitoring aspirin effect. | 2008 | Mol Diagn Ther | pmid:18288882 |
| Cooper TM and Ingram DM | Platelet function in the peri-operative period. | 1991 | Aust N Z J Surg | pmid:1829351 |
| Selg E et al. | Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung. | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18294831 |
| Ohkuma H et al. | Role of platelet function in symptomatic cerebral vasospasm following aneurysmal subarachnoid hemorrhage. | 1991 | Stroke | pmid:1830180 |
| Basselin M et al. | Chronic carbamazepine administration attenuates dopamine D2-like receptor-initiated signaling via arachidonic acid in rat brain. | 2008 | Neurochem. Res. | pmid:18302021 |
| Vanderhoek JY et al. | Inhibitory potencies of fish oil hydroxy fatty acids on cellular lipoxygenases and platelet aggregation. | 1991 | Biochem. Pharmacol. | pmid:1831021 |
| Menzies D et al. | Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma. | 2008 | J. Allergy Clin. Immunol. | pmid:18313127 |
| Wang L and Wang Z | [The effects of ilexonin A on AA metabolism]. | 1991 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:1831714 |
| Roethig HJ et al. | A 12-month, randomized, controlled study to evaluate exposure and cardiovascular risk factors in adult smokers switching from conventional cigarettes to a second-generation electrically heated cigarette smoking system. | 2008 | J Clin Pharmacol | pmid:18319361 |
| Mizuno M et al. | [The changes in plasma beta-thromboglobulin (beta-TG), platelet factor 4 (PF4) and thromboxane B2 (TXB2) after a bronchial provocation test (BPT) with house dust (HD) allergen]. | 1991 | Arerugi | pmid:1831967 |
| Al-Salam Z et al. | The effect of dobutamine on platelet aggregatory function in newborn piglets with hypoxia and reoxygenation. | 2008 | Shock | pmid:18323735 |
| Malle E et al. | Effects of dietary fish oil supplementation on platelet aggregability and platelet membrane fluidity in normolipemic subjects with and without high plasma Lp(a) concentrations. | 1991 | Atherosclerosis | pmid:1832537 |
| Momen A et al. | Local prostaglandin blockade attenuates muscle mechanoreflex-mediated renal vasoconstriction during muscle stretch in humans. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18326807 |
| Skoglund C et al. | C-reactive protein and C1q regulate platelet adhesion and activation on adsorbed immunoglobulin G and albumin. | 2008 | Immunol. Cell Biol. | pmid:18332893 |
| Brüne B and Ullrich V | Different calcium pools in human platelets and their role in thromboxane A2 formation. | 1991 | J. Biol. Chem. | pmid:1833401 |
| Helgason CM et al. | Platelet aggregation and recruitment with aspirin-clopidogrel therapy. | 2008 | Cerebrovasc. Dis. | pmid:18349532 |
| Udvardy M et al. | Alterations of primary haemostasis in mixed connective tissue disease (MCTD). | 1991 | Thromb. Res. | pmid:1835548 |
| Takayama K et al. | Changes in endothelial vasoactive substances under recombinant human erythropoietin therapy in hemodialysis patients. | 1991 Jul-Sep | ASAIO Trans | pmid:1836334 |
| Horton AA and Wood JM | Prevention of Ca(2+)-induced or thromboxane B2-induced hepatocyte plasma membrane bleb formation by thromboxane receptor antagonists. | 1991 | Biochim. Biophys. Acta | pmid:1836358 |
| Zahavi J et al. | An abnormal pattern of multiple platelet function abnormalities and increased thromboxane generation in patients with primary thrombocytosis and thrombotic complications. | 1991 | Eur. J. Haematol. | pmid:1836999 |
| Jennings PE et al. | The relationship of oxidative stress to thrombotic tendency in type 1 diabetic patients with retinopathy. | 1991 | Diabet. Med. | pmid:1837513 |
| Bruce EC et al. | Platelet thromboxane A2 secretion in patients with major depression responsive to electroconvulsive therapy. | 2008 | Psychosom Med | pmid:18378867 |
| Hiller E et al. | [Effect of molsidomine infusion on thrombocyte function in acute myocardial infarct]. | 1991 | Z Kardiol | pmid:1837969 |
| Wooten JG et al. | Cyclooxygenase expression and prostanoid production in pyloric and duodenal mucosae in dogs after administration of nonsteroidal anti-inflammatory drugs. | 2008 | Am. J. Vet. Res. | pmid:18380576 |
| Lesch ME et al. | The effects of (R)-N-(1-methyl-2-phenylethyl) adenosine (L-PIA), a standard A1-selective adenosine agonist on rat acute models of inflammation and neutrophil function. | 1991 | Agents Actions | pmid:1838897 |
| Hinz B et al. | Impact of naproxen sodium at over-the-counter doses on cyclooxygenase isoforms in human volunteers. | 2008 | Int J Clin Pharmacol Ther | pmid:18397691 |
| Liu Z | [Effects of Ligusticum wallichii on the plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2 and 6-keto-PGF1 alpha in patients with acute cerebral infarction]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:1840363 |
| Karon BS et al. | Aspirin responsiveness in healthy volunteers measured with multiple assay platforms. | 2008 | Clin. Chem. | pmid:18420732 |
| Maksimova MIu et al. | [Hemorheology and homeostasis in the most acute stage of lacunar stroke]. | 2007 | Zh Nevrol Psikhiatr Im S S Korsakova | pmid:18427452 |
| Schwartz JI et al. | Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects. | 2008 | J Clin Pharmacol | pmid:18434566 |
| Cui J et al. | Cyclooxygenase inhibition attenuates sympathetic responses to muscle stretch in humans. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18441194 |
| Rossoni G et al. | Combined simvastatin-manidipine protect against ischemia-reperfusion injury in isolated hearts from normocholesterolemic rats. | 2008 | Eur. J. Pharmacol. | pmid:18442813 |
| Koike T et al. | [Elevation of 11-dehydro-thromboxane B2 levels in unstable angina]. | 1991 | J Cardiol | pmid:1844445 |
| Basselin M et al. | Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats. | 2008 | Neurochem. Res. | pmid:18461450 |
| Mahida YR et al. | 5-Aminosalicylic acid is a potent inhibitor of interleukin 1 beta production in organ culture of colonic biopsy specimens from patients with inflammatory bowel disease. | 1991 | Gut | pmid:1846838 |
| Cambria RA et al. | Thromboxane synthetase inhibition decreases polymorphonuclear leukocyte activation following hindlimb ischemia. | 1991 | Am Surg | pmid:1847027 |
| Bernstrom K et al. | 14, 15-cis-episulfide-eicosatrienoic acid, an 'epoxygenase' eicosanoid analog, inhibits ionophore- but not thrombin-induced platelet aggregation. | 1991 | Mol. Pharmacol. | pmid:1847490 |
| Goldman G et al. | Intravascular chemoattractants inhibit diapedesis by selective receptor occupancy. | 1991 | Am. J. Physiol. | pmid:1847598 |
| Zheng H et al. | Attenuation of LPS-induced neutrophil thromboxane b2 release and chemiluminescence. | 1991 | J. Cell. Physiol. | pmid:1847934 |
| Elander N et al. | Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18485889 |
| Docherty JC and Wilson TW | Effect of indomethacin on arachidonic acid metabolism in human leukocytes stimulated ex vivo. | 1991 | Clin. Pharmacol. Ther. | pmid:1848800 |
| Knight KR et al. | Secondary ischaemia in rabbit skin flaps: the roles played by thromboxane and free radicals. | 1991 | Clin. Sci. | pmid:1850683 |
| Faint RW et al. | Platelet aggregation is inhibited by a nitric oxide-like factor released from human neutrophils in vitro. | 1991 | Br. J. Haematol. | pmid:1851034 |
| Awad H et al. | Intracellular and extracellular expression of the major inducible 70kDa heat shock protein in experimental ischemia-reperfusion injury of the spinal cord. | 2008 | Exp. Neurol. | pmid:18511046 |
| McClelland S et al. | Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse. | 2009 | Atherosclerosis | pmid:18514659 |
| Hocking DC et al. | Dextran sulfate inhibits PMN-dependent hydrostatic pulmonary edema induced by tumor necrosis factor. | 1991 | J. Appl. Physiol. | pmid:1851740 |
| Santilli F et al. | Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients. | 2008 | Blood | pmid:18541722 |
| Gao L et al. | [Effects of supplementing qi and activating blood circulation method on platelet aggregation rate, adhesion rate and thromboxane B2 level in patients with stable angina pectoris and intolerable to aspirin]. | 2008 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:18543479 |
| Patrignani P et al. | Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: a clinical biomarker study. | 2008 | Pharmacogenet. Genomics | pmid:18551041 |
| Yin K et al. | Blood pressure and vascular reactivity changes in spontaneously hypertensive rats fed fish oil. | 1991 | Br. J. Pharmacol. | pmid:1855129 |
| Fernández-Arche A et al. | Long-chain fatty alcohols from pomace olive oil modulate the release of proinflammatory mediators. | 2009 | J. Nutr. Biochem. | pmid:18555679 |
| Parsons JP et al. | Airway inflammation in exercise-induced bronchospasm occurring in athletes without asthma. | 2008 | J Asthma | pmid:18569228 |
| Yan Q et al. | Female ROMK null mice manifest more severe Bartter II phenotype on renal function and higher PGE2 production. | 2008 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:18579648 |
| Wander RC and Patton BD | Comparison of three species of fish consumed as part of a Western diet: effects on platelet fatty acids and function, hemostasis, and production of thromboxane. | 1991 | Am. J. Clin. Nutr. | pmid:1858697 |
| Coates AM et al. | Regular consumption of n-3 fatty acid-enriched pork modifies cardiovascular risk factors. | 2009 | Br. J. Nutr. | pmid:18590592 |
| Dobaczewski M et al. | Targeting the urine and plasma determinants of thromboxane A2 metabolism in detection of aspirin effectiveness. | 2008 | Blood Coagul. Fibrinolysis | pmid:18600093 |
| Olafsdottir K et al. | Hydroperoxide-induced broncho- and vasoconstriction in the isolated rat lung. | 1991 May-Jun | Exp. Lung Res. | pmid:1860458 |
| Moore TC et al. | In vivo influences of phorbol ester and calcium ionophore on lymphocyte traffic, lymph flow and efferent lymph levels of thromboxane B2 in sheep. | 1991 Jan-Feb | Immunopharmacology | pmid:1860782 |
| Guthikonda S et al. | Increased platelet sensitivity among individuals with aspirin resistance - platelet aggregation to submaximal concentration of arachidonic acid predicts response to antiplatelet therapy. | 2008 | Thromb. Haemost. | pmid:18612542 |
| Csányi G et al. | Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis. | 2008 May-Jun | Pharmacol Rep | pmid:18622059 |
| O'Neill PA et al. | Role of renal sympathetic nerve activity in renal failure associated with obstructive jaundice in the rat. | 1991 | Am. J. Surg. | pmid:1862825 |
| Abdelwhab S and Elshinnawy S | Pulmonary hypertension in chronic renal failure patients. | 2008 | Am. J. Nephrol. | pmid:18635926 |
| Zheng L et al. | [Changes of thromboxane A2 (TXA2) and prostacyclin (PGI2) in COPD patients with pulmonary hypertension]. | 1991 | Zhonghua Nei Ke Za Zhi | pmid:1864178 |
| Fishman SJ et al. | Cyclosporin A augments human platelet sensitivity to aggregating agents by increasing fibrinogen receptor availability. | 1991 | J. Surg. Res. | pmid:1865677 |
| Simmet T and Weide I | Thromboxane and cysteinyl-leukotriene formation are differentially activated in spontaneously clotting whole human blood in vitro. | 1991 | Thromb. Res. | pmid:1866709 |
| Magner P | Effects of sulindac on renal prostaglandins and glomerular filtration rate. | 1991 | Am. J. Med. | pmid:1867250 |
| Welbourn R et al. | Interleukin-2 induces early multisystem organ edema mediated by neutrophils. | 1991 | Ann. Surg. | pmid:1867524 |
| Aitokallio-Tallberg AM et al. | Urinary excretion of degradation products of prostacyclin and thromboxane is increased in patients with gestational choriocarcinoma. | 1991 | Cancer Res. | pmid:1868436 |