Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Osteoblastoma D018215 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Drowning D004332 2 associated lipids
Jejunal Diseases D007579 3 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Radiculopathy D011843 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Blair IA et al. Dietary stearic acid and thromboxane-prostacyclin biosynthesis in normal human subjects. 1994 Am. J. Clin. Nutr. pmid:7977150
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Zhang QZ et al. Effects of cyproheptadine on TXB2 and 6-keto-PGF1 alpha plasma levels in rabbits with hemorrhagic shock. 1994 Zhongguo Yao Li Xue Bao pmid:7976376
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Dabaghi SF et al. Effects of low-dose aspirin on in vitro platelet aggregation in the early minutes after ingestion in normal subjects. 1994 Am. J. Cardiol. pmid:7942533
Quereda C et al. Urinary thromboxane B2 and cyclic AMP in cyclosporine-A-treated kidney transplantation. 1994 Transplant. Proc. pmid:7940810
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Chiabrando C et al. Urinary excretion of 2,3-dinor-thromboxane B1, a major metabolite of thromboxane B2 in the rat. 1994 Prostaglandins pmid:7938613
Turi S et al. Laser aggregometer studies, ATP release and thromboxane B2 release and cAMP concentration of the platelets in nephrotic syndrome. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:7938102
Yanagisawa H et al. Dietary protein restriction in isolated glomeruli from rats with bilateral ureteral obstruction. 1994 Kidney Int. pmid:7933843
King JN Correlation between the pharmacokinetics of oxindanac and inhibition of serum thromboxane B2 in calves. 1994 J. Vet. Pharmacol. Ther. pmid:7933057
King JN et al. High performance liquid chromatography and pharmacokinetics of the non-steroidal anti-inflammatory drug oxindanac in calves. 1994 J. Vet. Pharmacol. Ther. pmid:7933056
Cozzi P et al. Agents combining thromboxane receptor antagonism with thromboxane synthase inhibition: [[[2-(1H-imidazol-1-yl)ethylidene]amino]oxy]alkanoic acids. 1994 J. Med. Chem. pmid:7932586
Walmrath D et al. Endotoxin "priming" potentiates lung vascular abnormalities in response to Escherichia coli hemolysin: an example of synergism between endo- and exotoxin. 1994 J. Exp. Med. pmid:7931076
Földes-Filep E et al. Pulmonary surfactant lipids inhibit prostanoid production of guinea pig alveolar macrophages. 1994 J. Leukoc. Biol. pmid:7930944
Clohisy JC et al. Prostanoid-induced expression of matrix metalloproteinase-1 messenger ribonucleic acid in rat osteosarcoma cells. 1994 Endocrinology pmid:7925106
Xu N [Effect of electroacupuncture at "taixi" point on plasma thromboxane A2 and prostacyclin in the rabbit with renal ischemia]. 1993 Zhen Ci Yan Jiu pmid:7923725
Tohjima T et al. In vitro effects of trapidil on fatty acid and prostaglandin metabolism in platelets. 1994 May-Jun Clin Ther pmid:7923307
Wu CC et al. Antiplatelet effects of clausine-D isolated from Clausena excavata. 1994 Biochim. Biophys. Acta pmid:7918571
Chiang MT et al. Lipoprotein, lecithin:cholesterol acyl transferase and acetyl CoA carboxylase in stroke-prone spontaneously hypertensive rats fed a diet high in eicosapentaenoic acid. 1994 Atherosclerosis pmid:7912508
Arimura A et al. Contribution of thromboxane A2 to the antigen-induced immediate asthmatic response mediated by IgG1 antibody by augmentation of bronchial responsiveness in guinea-pigs. 1994 Br. J. Pharmacol. pmid:7912155
D'Argenio G et al. Butyrate, mesalamine, and factor XIII in experimental colitis in the rat: effects on transglutaminase activity. 1994 Gastroenterology pmid:7905450
Fletcher MP et al. C5a-induced myocardial ischemia: role for CD18-dependent PMN localization and PMN-platelet interactions. 1993 Am. J. Physiol. pmid:7902015
Saldeen P et al. Lack of association between Doppler velocimetry and synthesis of prostacyclin and thromboxane in umbilical cord vessels from growth retarded fetuses. 1995 Acta Obstet Gynecol Scand pmid:7900504
Takeuchi K et al. Development of dual-acting agents for thromboxane receptor antagonism and thromboxane synthase inhibition--I. Synthesis, structure-activity relationship, and evaluation of substituted omega-phenyl-omega-(3-pyridyl)alkenoic acids. 1994 Bioorg. Med. Chem. pmid:7894968
Stratton MD et al. The effect of Clostridium difficile toxin on colonocyte prostanoid activity. 1994 Prostaglandins pmid:7892508
Hsyu PH et al. Pharmacokinetics and cyclooxygenase inhibition of itazigrel in normal volunteers after single oral doses. 1994 J Pharm Sci pmid:7891305
Haugen G et al. Effect of phenazone (antipyrine) on the prostanoid formation in human umbilical arteries perfused in vitro. 1995 Gynecol. Obstet. Invest. pmid:7890260
Hatori N et al. Biocompatibility of heparin-coated membrane oxygenator during cardiopulmonary bypass. 1994 Artif Organs pmid:7887827
Singh HP et al. Prostacyclin and thromboxane levels in pleural space fluid during cardiopulmonary bypass. 1995 Ann. Thorac. Surg. pmid:7887705