Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Osteoblastoma D018215 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Drowning D004332 2 associated lipids
Jejunal Diseases D007579 3 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Radiculopathy D011843 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
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Authors Title Published Journal PubMed Link
Snapper JR et al. Role of endothelin in endotoxin-induced sustained pulmonary hypertension in sheep. 1998 Am. J. Respir. Crit. Care Med. pmid:9445282
Dent G et al. Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils. 1998 Am. J. Respir. Cell Mol. Biol. pmid:9448055
Moore RM et al. Effect of platelet-activating factor antagonist L-691,880 on low-flow ischemia-reperfusion injury of the large colon in horses. 1998 Jan-Feb Vet Surg pmid:9449176
Parra T et al. Cyclosporine A nephrotoxicity: role of thromboxane and reactive oxygen species. 1998 J. Lab. Clin. Med. pmid:9452128
Yanagisawa H et al. Ureteral obstruction enhances eicosanoid production in cortical and medullary tubules of rat kidneys. 1997 Kidney Blood Press. Res. pmid:9453451
Erez E et al. Thromboxane production in human lung during cardiopulmonary bypass: beneficial effect of aspirin? 1998 Ann. Thorac. Surg. pmid:9456103
Chiba Y et al. Effects of depletion of leukocytes and platelets on cardiac dysfunction after cardiopulmonary bypass. 1998 Ann. Thorac. Surg. pmid:9456104
Hanaoka M et al. Effect of post-treatment with granulocyte colony-stimulating factor on endotoxin-induced lung injury in sheep. 1998 Jan-Feb Exp. Lung Res. pmid:9457466
Robbins DL et al. Effect of anticardiolipin/beta2-glycoprotein I complexes on production of thromboxane A2 by platelets from patients with the antiphospholipid syndrome. 1998 J. Rheumatol. pmid:9458202
Forastiero R et al. Anti-beta2 glycoprotein I antibodies and platelet activation in patients with antiphospholipid antibodies: association with increased excretion of platelet-derived thromboxane urinary metabolites. 1998 Thromb. Haemost. pmid:9459320
Keen HL et al. Maintenance of baseline angiotensin II potentiates insulin hypertension in rats. 1998 Hypertension pmid:9461234
Liao CH et al. Bakkenolide G, a natural PAF-receptor antagonist. 1997 J. Pharm. Pharmacol. pmid:9466352
Kruse-Elliott KT et al. Role of lipid-derived mediators in tumor necrosis factor-induced endothelin-1 release in vivo. 1998 Shock pmid:9466472
Fadok VA et al. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. 1998 J. Clin. Invest. pmid:9466984
Fujita M et al. Effects of a specific cysteinyl leukotriene antagonist, pranlukast, on antigen-induced cysteinyl leukotriene-mediated rhinitis in guinea pigs. 1997 Jpn. J. Pharmacol. pmid:9469640
Chang MC et al. Antithrombotic effect of crotalin, a platelet membrane glycoprotein Ib antagonist from venom of Crotalus atrox. 1998 Blood pmid:9473223
Yamanobe S et al. Analysis of urinary 11-dehydrothromboxane B2 in patients with occluded retinal vein using GC/SIM. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9482168
Nieuwenhuys CM and Hornstra G The effects of purified eicosapentaenoic and docosahexaenoic acids on arterial thrombosis tendency and platelet function in rats. 1998 Biochim. Biophys. Acta pmid:9487152
Provost P et al. Platelets, neutrophils, and vasoconstriction after arterial injury by angioplasty in pigs: effects of MK-886, a leukotriene biosynthesis inhibitor. 1998 Br. J. Pharmacol. pmid:9489613
Takeda H et al. Time course study for airway inflammation and responsiveness by repeated provocation of aeroantigen in guinea pigs. 1997 Prostaglandins pmid:9491210