Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Osteoblastoma D018215 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Drowning D004332 2 associated lipids
Jejunal Diseases D007579 3 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Radiculopathy D011843 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Suliman HB et al. Prevention of influenza-induced lung injury in mice overexpressing extracellular superoxide dismutase. 2001 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:11133496
Buccellati C et al. Tramadol anti-inflammatory activity is not related to a direct inhibitory action on prostaglandin endoperoxide synthases. 2000 Eur J Pain pmid:11124014
De Jong A et al. Antiphospholipid antibodies and platelets. 2000 Curr Rheumatol Rep pmid:11123065
Moosig F et al. Opsonization of apoptotic neutrophils by anti-neutrophil cytoplasmic antibodies (ANCA) leads to enhanced uptake by macrophages and increased release of tumour necrosis factor-alpha (TNF-alpha). 2000 Clin. Exp. Immunol. pmid:11122261
Kasahara M et al. Effect of FK3311 on ischemia-reperfusion injury in canine pulmonary models. 2000 Transplant. Proc. pmid:11120230
De La Cruz JP et al. Antithrombotic potential of olive oil administration in rabbits with elevated cholesterol. 2000 Thromb. Res. pmid:11113274
Armstrong RA et al. No effect of dietary trans isomers of alpha-linolenic acid on platelet aggregation and haemostatic factors in european healthy men. The TRANSLinE study. 2000 Thromb. Res. pmid:11108899
Basu S et al. Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity. 2000 Clin. Sci. pmid:11099394
Cruz MA et al. Vascular reactivity to angiotensin II and eicosanoid production in the human placenta from term and preterm pregnancy. 2000 Gynecol. Obstet. Invest. pmid:11093047
Darlametsos IE et al. Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: roles of the thromboxane and endothelin systems. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11090252
Praticò D et al. Endogenous biosynthesis of thromboxane and prostacyclin in 2 distinct murine models of atherosclerosis. 2000 Blood pmid:11090066
Naito Y et al. Increase in blood pressure with enhanced Na+, K+ -ATPase activity in stroke-prone spontaneously hypertensive rats after 4-weeks intake of rapeseed oil as the sole dietary fat. 2000 Pharmacol. Toxicol. pmid:11068856
Vazquez-Cruz B et al. Increased renal vasoconstriction and gene expression of cyclooxygenase-1 in renovascular hypertension. 2000 J. Cardiovasc. Pharmacol. pmid:11065217
Kawasaki K et al. Inhibition of 12(S)-hydroxyeicosatetraenoic acid (12-HETE) production suppressed the intimal hyperplasia caused by poor-runoff conditions in the rabbit autologous vein grafts. 2000 J. Cardiovasc. Pharmacol. pmid:11065214
Ferry DR et al. A phase II study of the 5-lipoxygenase inhibitor, CV6504, in advanced pancreatic cancer: correlation of clinical data with pharmacokinetic and pharmacodynamic endpoints. 2000 Ann. Oncol. pmid:11061613
Suzuki N et al. Difference in urinary LTE4 and 11-dehydro-TXB2 excretion in asthmatic patients. 2000 Prostaglandins Other Lipid Mediat. pmid:11060902
De Somer F et al. Phosphorylcholine coating of extracorporeal circuits provides natural protection against blood activation by the material surface. 2000 Eur J Cardiothorac Surg pmid:11053824
Rahman K and Billington D Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans. 2000 J. Nutr. pmid:11053504
Qu X et al. Selenium deficiency-induced alterations in the vascular system of the rat. 2000 Biol Trace Elem Res pmid:11051602
Thomson M et al. Thromboxane-B(2) levels in serum of rabbits receiving a single intravenous dose of aqueous extract of garlic and onion. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11049697
Delemarre FM et al. Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11049696
Parker CR et al. Umbilical cord serum levels of thromboxane B2 in term infants of women who participated in a placebo-controlled trial of low-dose aspirin. 2000 Jul-Aug J Matern Fetal Med pmid:11048830
Filipov NM et al. Anti-inflammatory effects of ergotamine in steers. 2000 Proc. Soc. Exp. Biol. Med. pmid:11044256
Boyle JR et al. Endovascular AAA repair attenuates the inflammatory and renal responses associated with conventional surgery. 2000 J. Endovasc. Ther. pmid:11032254
Ciabattoni G et al. In vivo lipid peroxidation and platelet activation in cystic fibrosis. 2000 Am. J. Respir. Crit. Care Med. pmid:11029317
Van Hecken A et al. Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers. 2000 J Clin Pharmacol pmid:11028250
Jacoby RF et al. The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. 2000 Cancer Res. pmid:11016626
Kim WG et al. Is avoidance of air contact necessary for the in vitro evaluation of thrombogenicity in mechanical circulatory assist devices? 2000 Artif Organs pmid:11012543
Coppola A et al. Homocysteine, coagulation, platelet function, and thrombosis. 2000 Semin. Thromb. Hemost. pmid:11011842
Tanaka H et al. Effects of milrinone on platelet aggregation in swine with pulmonary hypertension. 2000 J Crit Care pmid:11011824
de Jong CL et al. Maternal thromboxane and prostacyclin levels in relation to fetal birth weight. 2000 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:11000507
WÅ‚odarczyk Z et al. Effects of pentoxifylline treatment on delayed graft function in cadaveric kidney recipients. 2000 Transplant. Proc. pmid:10995988
Boatman RJ et al. Covalent protein adducts of hydroquinone in tissues from rats: quantitation of sulfhydryl-bound forms following single gavage or intraperitoneal administration or repetitive gavage administration. 2000 Chem. Res. Toxicol. pmid:10995259
Matz RL et al. Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids. 2000 Br. J. Pharmacol. pmid:10991924
van Haeringen NJ et al. Flurbiprofen and enantiomers in ophthalmic solution tested as inhibitors of prostanoid synthesis in human blood. 2000 J Ocul Pharmacol Ther pmid:10977130
Sabha M et al. Transdermal nicotine mimics the smoking-induced endothelial dysfunction. 2000 Clin. Pharmacol. Ther. pmid:10976548
Yuk DY et al. Antithrombotic and antiplatelet activities of 2-chloro-3-[4-(ethylcarboxy)-phenyl]-amino-1,4-naphthoquinone (NQ12), a newly synthesized 1,4-naphthoquinone derivative. 2000 Biochem. Pharmacol. pmid:10974210
Togna GI et al. Cisplatin triggers platelet activation. 2000 Thromb. Res. pmid:10973681
Ohata T et al. Role of nitric oxide in a temperature dependent regulation of systemic vascular resistance in cardiopulmonary bypass. 2000 Eur J Cardiothorac Surg pmid:10973545
Arakida Y et al. Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs. 2000 Eur. J. Pharmacol. pmid:10969159
Siler-Khodr TM et al. Effect of ethanol on thromboxane and prostacyclin production in the human placenta. 2000 Alcohol pmid:10963940
Belton O et al. Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. 2000 Circulation pmid:10952950
Kelly JP et al. Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway. 1979 J. Immunol. pmid:109510
McCann ME et al. Effect of intravenous infusion of omega-3 and omega-6 lipid emulsions on equine monocyte fatty acid composition and inflammatory mediator production in vitro. 2000 Shock pmid:10947170
Thorwest M et al. Dietary fish oil reduces microvascular thrombosis in a porcine experimental model. 2000 Thromb. Res. pmid:10946095
Stanke-Labesque F et al. Angiotensin II-induced contractions in human internal mammary artery: effects of cyclooxygenase and lipoxygenase inhibition. 2000 Cardiovasc. Res. pmid:10946074
Krysztopik RJ et al. Lazaroid and pentoxifylline suppress sepsis-induced increases in renal vascular resistance via altered arachidonic acid metabolism. 2000 J. Surg. Res. pmid:10945946
Sane S et al. Eicosapentaenoic acid reduces pulmonary edema in endotoxemic rats. 2000 J. Surg. Res. pmid:10945939
Porta C et al. Amifostine, a reactive oxigen species scavenger with radiation- and chemo-protective properties, inhibits in vitro platelet activation induced by ADP, collagen or PAF. 2000 Haematologica pmid:10942928
Tsikas D et al. Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine. 2000 J Chromatogr A pmid:10941682
Kim WG et al. Vasoconstrictive eicosanoid responses to extracorporeal circulation with or without an oxygenator in fetal lambs. 2000 Int J Artif Organs pmid:10941636
Kamata K et al. Altered endothelium-dependent and -independent hyperpolarization and endothelium-dependent relaxation in carotid arteries isolated from streptozotocin-induced diabetic rats. 2000 Naunyn Schmiedebergs Arch. Pharmacol. pmid:10935533
Wang JS et al. Effect of strenuous arm exercise on oxidized-LDL-potentiated platelet activation in individuals with spinal cord injury. 2000 Thromb. Haemost. pmid:10928481
Muscará MN et al. Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10924050
Dschietzig T et al. Stimulation of pulmonary big endothelin-1 and endothelin-1 by antithrombin III: a rationale for combined application of antithrombin III and endothelin antagonists in sepsis-related acute respiratory distress syndrome? 2000 Crit. Care Med. pmid:10921577
Patrignani P et al. Effects of vitamin E supplementation on F(2)-isoprostane and thromboxane biosynthesis in healthy cigarette smokers. 2000 Circulation pmid:10920066
MalatyalioÄŸlu E et al. Levels of stable metabolites of prostacyclin and thromboxane A2 and their ratio in normotensive and preeclamptic pregnant women during the antepartum and postpartum periods. 2000 May-Jun J Matern Fetal Med pmid:10914626
Ogura Y et al. Chemoprevention of biliary carcinogenesis in syrian hamsters by the novel carboxamide derivative IS-741 after initiation with N-nitrosobis(2-oxopropyl)amine (BOP). 2000 Carcinogenesis pmid:10910946
Momi S et al. Involvement of platelets in experimental mouse trypanosomiasis: evidence of mouse platelet cytotoxicity against Trypanosoma equiperdum. 2000 Exp. Parasitol. pmid:10910715
Giedrojć J et al. [Investigation of prostaglandins in supernatant of cultured monocytes]. 2000 Prz. Lek. pmid:10907365
Toft G et al. Intravenously and topically applied magnesium in the prevention of arterial thrombosis. 2000 Thromb. Res. pmid:10904104
Köfeler HC et al. Effect of cytochrome P-450 inhibitors econazole, bifonazole and clotrimazole on prostanoid formation. 2000 Br. J. Pharmacol. pmid:10903961
Sugimoto KI et al. Delayed hypotensive effect of the thromboxane A2/prostaglandin H2 receptor antagonist S-1452 in spontaneously hypertensive rats. 2000 Clin. Exp. Pharmacol. Physiol. pmid:10901388
Cayatte AJ et al. The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo E-deficient mice: evidence that eicosanoids other than thromboxane contribute to atherosclerosis. 2000 Arterioscler. Thromb. Vasc. Biol. pmid:10894809
Rao AR and Prabhakar MC Screening methods for antiasthmatic agents. 2000 Methods Find Exp Clin Pharmacol pmid:10893704
Bailey SR et al. Differential activation of platelets from normal and allergic ponies by PAF and ADP. 2000 Inflamm. Res. pmid:10893045
Kowalska MA et al. Stromal cell-derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets. 2000 Blood pmid:10891429
Bereczki C et al. The roles of platelet function, thromboxane, blood lipids and nitric oxide in hypertension of children and adolescents. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10883060
Lasserre B et al. Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10883059
Moon CH et al. Mechanism for antiplatelet effect of onion: AA release inhibition, thromboxane A(2)synthase inhibition and TXA(2)/PGH(2)receptor blockade. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10883058
Depré M et al. Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans. 2000 Eur. J. Clin. Pharmacol. pmid:10877012
Mizugaki M [Microdetermination of eicosanoids using mass spectrometry]. 2000 Nippon Yakurigaku Zasshi pmid:10876809
Theriot JA et al. Dietary chloride does not correlate with urinary thromboxane in deoxycorticosterone acetate-treated rats. 2000 J. Lab. Clin. Med. pmid:10850649
Carty E et al. Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. 2000 Aliment. Pharmacol. Ther. pmid:10848666
Tran HS et al. The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock. 2000 Shock pmid:10847636
Rioja I et al. An anti-inflammatory ditriazine inhibiting leukocyte functions and expression of inducible nitric oxide synthase and cyclo-oxygenase-2. 2000 Eur. J. Pharmacol. pmid:10844115
Cracowski JL et al. Human internal mammary artery contraction by isoprostaglandin f(2alpha) type-III [8-iso-prostaglandin F(2alpha)]. 2000 Eur. J. Pharmacol. pmid:10844110
Sakamoto K et al. An imbalance in plasma prostanoids in patients with Raynaud's phenomenon and pulmonary vasospasm. 1999 Eur. Respir. J. pmid:10836338
Numminen H et al. The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation. 2000 Stroke pmid:10835443
Semenov AV et al. [Soluble P-selectin - a marker of platelet activation and vessel wall injury: increase of soluble P-selectin in plasma of patients with myocardial infarction, massive atherosclerosis and primary pulmonary hypertension]. 2000 Ter. Arkh. pmid:10833791
Maccarrone M et al. Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells. 2000 Biochem. Biophys. Res. Commun. pmid:10833416
Nosál' R et al. Chloroquine: a multipotent inhibitor of human platelets in vitro. 2000 Thromb. Res. pmid:10828481
Sheu JR et al. Mechanisms involved in the antiplatelet activity of Staphylococcus aureus lipoteichoic acid in human platelets. 2000 Thromb. Haemost. pmid:10823277
Romano M et al. Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide. 2000 J. Investig. Med. pmid:10822898
Turpeinen AM et al. Similar responses in hemostatic factors after consumption of wholemeal rye bread and low-fiber wheat bread. 2000 Eur J Clin Nutr pmid:10822290
Tanus-Santos JE et al. Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. 2000 Eur. J. Pharmacol. pmid:10822051
Jacobi KE et al. Determination of eicosanoid and cytokine production in salvaged blood, stored red blood cell concentrates, and whole blood. 2000 J Clin Anesth pmid:10818321
Gardan B et al. Vasoconstrictor effects of iso-prostaglandin F2alpha type-III (8-iso-prostaglandin F2alpha) on human saphenous veins. 2000 J. Cardiovasc. Pharmacol. pmid:10813374
Wakitani K et al. JTE-522 selectively inhibits cyclooxygenase-2-derived prostaglandin production in inflammatory tissues. 2000 Inflamm. Res. pmid:10807499
Zhao S et al. Glioma prostaglandin levels correlate with brain edema. 1998 J. Tongji Med. Univ. pmid:10806839
Jacobs C et al. 1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase. 2000 J. Med. Chem. pmid:10794700
Agnoli GC et al. Renal synthesis of prostacyclin and thromboxane in healthy women: differential effects of a short-term saline loading. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780876
Heller A et al. The complement regulators C1 inhibitor and soluble complement receptor 1 attenuate acute lung injury in rabbits. 2000 Shock pmid:10774617
Prieto MA et al. Influence of triflusal on platelet activation after coronary artery bypass graft. 2000 Blood Coagul. Fibrinolysis pmid:10759013
Liao CH et al. Antiplatelet effect of marchantinquinone, isolated from Reboulia hemisphaerica, in rabbit washed platelets. 2000 J. Pharm. Pharmacol. pmid:10757426
Bailey SR et al. Actions and interactions of ADP, 5- HT, histamine and PAF on equine platelets. 2000 Res. Vet. Sci. pmid:10756136
Nenci GG and Paliani U [Diabetes, coagulation and vascular events]. 2000 Recenti Prog Med pmid:10748654
Schweizer A et al. Aprotinin does not impair renal haemodynamics and function after cardiac surgery. 2000 Br J Anaesth pmid:10740541
Homoncik M et al. Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100. 2000 Thromb. Haemost. pmid:10739392
Jacobi K et al. Plasma levels of eicosanoids after transfusion of intraoperatively salvaged blood. 2000 Vox Sang. pmid:10729809