| MeSH term | MeSH ID | Detail |
|---|---|---|
| Osteoblastoma | D018215 | 1 associated lipids |
| Erythromelalgia | D004916 | 1 associated lipids |
| Fibromuscular Dysplasia | D005352 | 2 associated lipids |
| Atrial Premature Complexes | D018880 | 1 associated lipids |
| Latex Hypersensitivity | D020315 | 1 associated lipids |
| Drowning | D004332 | 2 associated lipids |
| Jejunal Diseases | D007579 | 3 associated lipids |
| Basal Ganglia Hemorrhage | D020145 | 1 associated lipids |
| Radiculopathy | D011843 | 1 associated lipids |
| Intracranial Hemorrhage, Hypertensive | D020299 | 1 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kranzhofer R and Ruef J | Aspirin resistance in coronary artery disease is correlated to elevated markers for oxidative stress but not to the expression of cyclooxygenase (COX) 1/2, a novel COX-1 polymorphism or the PlA(1/2) polymorphism. | 2006 | Platelets | pmid:16702043 |
| Chen GG et al. | Increased thromboxane B(2) levels are associated with lipid peroxidation and Bcl-2 expression in human lung carcinoma. | 2006 | Cancer Lett. | pmid:15876485 |
| Sailaja Devi MM and Das UN | Effect of prostaglandins against alloxan-induced diabetes mellitus. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16297610 |
| Kanda N and Watanabe S | Suppressive effects of antimycotics on tumor necrosis factor-alpha-induced CCL27, CCL2, and CCL5 production in human keratinocytes. | 2006 | Biochem. Pharmacol. | pmid:16784723 |
| Dołegowska B et al. | Metabolism of eicosanoids and their action on renal function during ischaemia and reperfusion: the effect of alprostadil. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17011760 |
| Ong TZ et al. | Nonsteroidal anti-inflammatory drug use is a significant cause of peptic ulcer disease in a tertiary hospital in Singapore: a prospective study. | 2006 | J. Clin. Gastroenterol. | pmid:17016134 |
| Morchón R et al. | High levels of serum thromboxane B2 are generated during human pulmonary dirofilariosis. | 2006 | Clin. Vaccine Immunol. | pmid:17028222 |
| Cook-Johnson RJ et al. | Endothelial cell COX-2 expression and activity in hypoxia. | 2006 | Biochim. Biophys. Acta | pmid:17046322 |
| Faraday N et al. | Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population. | 2006 | Am. J. Cardiol. | pmid:16950183 |
| Renda G et al. | Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease. | 2006 | Clin. Pharmacol. Ther. | pmid:16952493 |
| Gabler NK et al. | Dietary onion intake as part of a typical high fat diet improves indices of cardiovascular health using the mixed sex pig model. | 2006 | Plant Foods Hum Nutr | pmid:17123162 |
| Venturinelli ML et al. | Platelet activation in different clinical forms of the coronary artery disease (role of P-selectin and others platelet markers in stable and unstable angina). | 2006 | Arq. Bras. Cardiol. | pmid:17128313 |
| Friton GM et al. | Clinical and anti-inflammatory effects of treating endotoxin-challenged pigs with meloxicam. | 2006 | Vet. Rec. | pmid:17056651 |
| Ma K et al. | [Study on comparative pharmacology of series of Muskone]. | 2006 | Zhongguo Zhong Yao Za Zhi | pmid:17061560 |
| Myers SI et al. | Oxygen-radical regulation of renal blood flow following suprarenal aortic clamping. | 2006 | J. Vasc. Surg. | pmid:16520177 |
| Fu JH et al. | [Protective effects of saponines of stem and leaf of Panax notoginseng on acute myocardial ischemia in anaesthetic dogs]. | 2006 | Zhongguo Zhong Yao Za Zhi | pmid:16548173 |
| Kanazawa S et al. | Aspirin reduces adverse effects of gefitinib. | 2006 | Anticancer Drugs | pmid:16550000 |
| Lee KS et al. | Anti-platelet activity of KR-32560, a novel sodium/hydrogen exchanger-1 inhibitor. | 2006 | Pharmacol. Res. | pmid:16420980 |
| Yin M et al. | [Experimental study of effects of cyclooxygenase-2 inhibitor on apoptosis of hypoxic myocardial cells in vitro]. | 2006 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:16647015 |
| Ahmad S et al. | Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and whole blood. | 2006 | Eur. J. Pharmacol. | pmid:16650843 |
| Fontana P et al. | Biological effects of aspirin and clopidogrel in a randomized cross-over study in 96 healthy volunteers. | 2006 | J. Thromb. Haemost. | pmid:16634751 |
| Markuszewski L et al. | Reduced blood platelet sensitivity to aspirin in coronary artery disease: are dyslipidaemia and inflammatory states possible factors predisposing to sub-optimal platelet response to aspirin? | 2006 | Basic Clin. Pharmacol. Toxicol. | pmid:16635110 |
| Treiber G et al. | The effect of single-dose naproxen on eicosanoid formation in human gastroduodenal mucosa. | 2006 | Aliment. Pharmacol. Ther. | pmid:16393293 |
| Nakamura K et al. | Effects of atorvastatin and aspirin combined therapy on inflammatory responses in patients undergoing coronary artery bypass grafting. | 2006 | Cytokine | pmid:17300951 |
| Park HS et al. | Dietary trans-10, cis-12 and cis-9,trans-11 conjugated linoleic acids induce apoptosis in the colonic mucosa of rats treated with 1,2-dimethylhydrazine. | 2006 | J Med Food | pmid:16579724 |
| Ohmori T et al. | Aspirin resistance detected with aggregometry cannot be explained by cyclooxygenase activity: involvement of other signaling pathway(s) in cardiovascular events of aspirin-treated patients. | 2006 | J. Thromb. Haemost. | pmid:16706971 |
| Perneby C et al. | Dose- and time-dependent antiplatelet effects of aspirin. | 2006 | Thromb. Haemost. | pmid:16601836 |
| Ahmadzadehfar H et al. | Passive cigarette smoking increases isoprostane formation. | 2006 | Life Sci. | pmid:16165164 |
| Lee KS et al. | Effects of DK-002, a synthesized (6aS,cis)-9,10-Dimethoxy-7,11b-dihydro-indeno[2,1-c]chromene-3,6a-diol, on platelet activity. | 2006 | Life Sci. | pmid:16153663 |
| Eligini S et al. | Indobufen inhibits tissue factor in human monocytes through a thromboxane-mediated mechanism. | 2006 | Cardiovasc. Res. | pmid:16154551 |
| Nobutoki T et al. | Fluctuating hearing loss, episodic headache, and stroke with platelet hyperaggregability: coexistence of auditory neuropathy and cochlear hearing loss. | 2006 | Brain Dev. | pmid:16168600 |
| Fujimoto Y et al. | Monochloramine potently inhibits arachidonic acid metabolism in rat platelets. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16615995 |
| Santilli F et al. | Thromboxane-dependent CD40 ligand release in type 2 diabetes mellitus. | 2006 | J. Am. Coll. Cardiol. | pmid:16412866 |
| Cao D et al. | Chronic administration of ethyl docosahexaenoate reduces gerbil brain eicosanoid productions following ischemia and reperfusion. | 2006 | J. Nutr. Biochem. | pmid:16098734 |
| Xu S et al. | The thromboxane receptor antagonist S18886 attenuates renal oxidant stress and proteinuria in diabetic apolipoprotein E-deficient mice. | 2006 | Diabetes | pmid:16380483 |
| Sánchez M et al. | Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats. | 2006 | J. Hypertens. | pmid:16331104 |
| Yang YY et al. | Roles of anandamide in the hepatic microcirculation in cirrhotic rats. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16407591 |
| Cyrus T et al. | Stabilization of advanced atherosclerosis in low-density lipoprotein receptor-deficient mice by aspirin. | 2006 | Atherosclerosis | pmid:16326168 |
| Mauri P et al. | LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity. | 2006 | J Pharm Biomed Anal | pmid:16343838 |
| Michel F et al. | Thromboxane A2/prostaglandin H2 receptor activation mediates angiotensin II-induced postischemic neovascularization. | 2006 | Arterioscler. Thromb. Vasc. Biol. | pmid:16385086 |
| Murphy KJ et al. | Low dose supplementation with two different marine oils does not reduce pro-inflammatory eicosanoids and cytokines in vivo. | 2006 | Asia Pac J Clin Nutr | pmid:16837436 |
| González-Correa JA et al. | Influence of vitamin E on the antiplatelet effect of acetylsalicylic acid in human blood. | 2005 May-Jun | Platelets | pmid:16011961 |
| Zhao Y et al. | [The effect of desloratadine on the TXB2 and leukotrienes levels in the nasal lavage fluid of allergic rhinitis animal model]. | 2005 | Lin Chuang Er Bi Yan Hou Ke Za Zhi | pmid:16075993 |
| Yoshino T et al. | Pharmacological profile of celecoxib, a specific cyclooxygenase-2 inhibitor. | 2005 | Arzneimittelforschung | pmid:16080279 |
| Chan CP et al. | Inhibition of cyclooxygenase activity, platelet aggregation and thromboxane B2 production by two environmental toxicants: m- and o-cresol. | 2005 | Toxicology | pmid:15664436 |
| Massicot F et al. | In vitro assessment of renal toxicity and inflammatory events of two protein phosphatase inhibitors cantharidin and nor-cantharidin. | 2005 | Basic Clin. Pharmacol. Toxicol. | pmid:15667592 |
| Lee GY et al. | Antiplatelet activity of BRX-018, (6aS,cis)-malonic acid 3-acetoxy-6a9-bis-(2-methoxycarbonyl-acetoxy)-6,6a,7,11b-tetrahydro-indeno[2,1-c]chromen-10-yl ester methylester. | 2005 | Thromb. Res. | pmid:15668191 |
| Gama de Abreu M et al. | Vaporized perfluorohexane attenuates ventilator-induced lung injury in isolated, perfused rabbit lungs. | 2005 | Anesthesiology | pmid:15731599 |
| Ye T et al. | [Insulin resistance and effects of intravenous acute saline load on renal production of prostaglandin I2 and thromboxane A2 in salt-sensitive hypertensive patients]. | 2005 | Di Yi Jun Yi Da Xue Xue Bao | pmid:15684012 |
| Arakawa K et al. | Bradykinin B2 receptor antagonist FR173657 ameliorates small bowel ischemia-reperfusion injury in dogs. | 2005 | Dig. Dis. Sci. | pmid:15712633 |
| Pampolina C and McNicol A | Streptococcus sanguis-induced platelet activation involves two waves of tyrosine phosphorylation mediated by FcgammaRIIA and alphaIIbbeta3. | 2005 | Thromb. Haemost. | pmid:15886812 |
| Ikonomidis I et al. | Cigarette smoking is associated with increased circulating proinflammatory and procoagulant markers in patients with chronic coronary artery disease: effects of aspirin treatment. | 2005 | Am. Heart J. | pmid:15894964 |
| Petrikova M et al. | Carvedilol--a beta-blocker with considerable antiaggregatory effect on human blood platelets. | 2005 | Bratisl Lek Listy | pmid:15869009 |
| Komers R et al. | Renal cyclooxygenase-2 in obese Zucker (fatty) rats. | 2005 | Kidney Int. | pmid:15882258 |
| Chang P et al. | Therapeutic effects and possible mechanisms of a snake venom preparation in the fibrotic rat liver. | 2005 | Dig. Dis. Sci. | pmid:15844712 |
| Bowen RS et al. | Increased phospholipase A2 and thromboxane but not prostacyclin production by placental trophoblast cells from normal and preeclamptic pregnancies cultured under hypoxia condition. | 2005 | Placenta | pmid:15850645 |
| Myers SI et al. | Bile duct ligation induced acute inflammation up-regulates cyclooxygenase-2 content and PGE2 release in guinea pig gallbladder smooth muscle cell cultures. | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15850713 |
| Nakamura K et al. | Influence of preoperative administration of omega-3 fatty acid-enriched supplement on inflammatory and immune responses in patients undergoing major surgery for cancer. | 2005 | Nutrition | pmid:15925286 |
| Coppola A et al. | Reduced in vivo oxidative stress following 5-methyltetrahydrofolate supplementation in patients with early-onset thrombosis and 677TT methylenetetrahydrofolate reductase genotype. | 2005 | Br. J. Haematol. | pmid:16173969 |
| Blume C et al. | Different effect of cyclosporine A and mycophenolate mofetil on passive Heymann nephritis in the rat. | 2005 | Nephron Exp. Nephrol. | pmid:15855806 |
| Giraudel JM et al. | Development of in vitro assays for the evaluation of cyclooxygenase inhibitors and predicting selectivity of nonsteroidal anti-inflammatory drugs in cats. | 2005 | Am. J. Vet. Res. | pmid:15900953 |
| Song YM et al. | Effects of scorpion venom bioactive polypolypeptides on platelet aggregation and thrombosis and plasma 6-keto-PG F1alpha and TXB2 in rabbits and rats. | 2005 | Toxicon | pmid:15975616 |
| Hsiao G et al. | Protective mechanisms of inosine in platelet activation and cerebral ischemic damage. | 2005 | Arterioscler. Thromb. Vasc. Biol. | pmid:15976325 |
| Barbara J et al. | Prevention of latex sensitization in guinea pigs by a bacterial and viral filter used in anaesthesia. | 2005 | Br J Anaesth | pmid:15980041 |
| Wu CC et al. | 2-(2-Br-phenyl)-8-methoxy-benzoxazinone (HPW-RX2), a direct thrombin inhibitor with a suppressive effect on thromboxane formation in platelets. | 2005 | Eur. J. Pharmacol. | pmid:16313903 |
| Visioli F et al. | Virgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients. | 2005 | Eur J Nutr | pmid:15309433 |
| Jin YR et al. | Antiplatelet activity of J78 (2-Chloro-3-[2'-bromo, 4'-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), an antithrombotic agent, is mediated by thromboxane (TX) A2 receptor blockade with TXA2 synthase inhibition and suppression of cytosolic Ca2+ mobilization. | 2005 | J. Pharmacol. Exp. Ther. | pmid:15328379 |
| Zhu S et al. | [Influence of Minkeqing oral liquid on IL-6, IL-8, ET-1, TX-B2 in blood and to observe bronchoalveolar lavage fluid of the rat with inhalating ovalbumin]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16161448 |
| Corazzi T et al. | Direct and irreversible inhibition of cyclooxygenase-1 by nitroaspirin (NCX 4016). | 2005 | J. Pharmacol. Exp. Ther. | pmid:16144976 |
| Haubelt H et al. | Can platelet function tests predict the clinical efficacy of aspirin? | 2005 | Semin. Thromb. Hemost. | pmid:16149017 |
| Ueda T and Hashimoto T | [Thromboxane A2 (TXA2), thromboxane B2 (TXB2)]. | 2005 | Nippon Rinsho | pmid:16149442 |
| Francois H et al. | Prostacyclin protects against elevated blood pressure and cardiac fibrosis. | 2005 | Cell Metab. | pmid:16154102 |
| Hsiao G et al. | Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. | 2005 | J. Lab. Clin. Med. | pmid:16194683 |
| Xiaorong C et al. | Effects of medicinal cake-separated moxibustion on plasma 6-keto-PGF1alpha and TXB2 contents in the rabbit of hyperlipemia. | 2005 | J Tradit Chin Med | pmid:16136949 |
| Cao D et al. | Chronic administration of ethyl docosahexaenoate decreases mortality and cerebral edema in ischemic gerbils. | 2005 | Life Sci. | pmid:16214179 |
| Léger CL et al. | A thromboxane effect of a hydroxytyrosol-rich olive oil wastewater extract in patients with uncomplicated type I diabetes. | 2005 | Eur J Clin Nutr | pmid:15798774 |
| Stichtenoth DO et al. | Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers. | 2005 | Kidney Int. | pmid:16221219 |
| Saloheimo P et al. | Thromboxane and prostacyclin biosynthesis in patients with acute spontaneous intracerebral hemorrhage. | 2005 | Thromb. Res. | pmid:15733969 |
| Fimognari FL et al. | Nocturnal rise of urinary thromboxane B 2 in patients with coronary artery disease. | 2005 | Thromb. Haemost. | pmid:15735822 |
| Mayer AM et al. | Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines. | 2005 | BMC Pharmacol. | pmid:15762999 |
| Kalaitzis C et al. | Effects of renal denervation of the contralateral kidney on blood pressure and sodium and eicosanoid excretion in the chronic phase of two-kidney, one-clip renovascular hypertension in rats. | 2005 | Scand. J. Urol. Nephrol. | pmid:15764265 |
| GarcÃa-Saura MF et al. | Effects of chronic quercetin treatment in experimental renovascular hypertension. | 2005 | Mol. Cell. Biochem. | pmid:15792364 |
| Watanabe H et al. | Effects of salt loading on blood pressure in mice lacking the prostanoid receptor gene. | 2005 | Circ. J. | pmid:15635218 |
| Lappegård KT et al. | Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production. | 2005 | Ann. Thorac. Surg. | pmid:15734405 |
| Maruyama T et al. | Thromboxane-dependent portopulmonary hypertension. | 2005 | Am. J. Med. | pmid:15639216 |
| Sciulli MG et al. | Platelet activation in patients with colorectal cancer. | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15626589 |
| Gonzalez-Conejero R et al. | Biological assessment of aspirin efficacy on healthy individuals: heterogeneous response or aspirin failure? | 2005 | Stroke | pmid:15604423 |
| Zheng YN et al. | Effects of compounds in leaves of Salix matsudana on arachidonic acid metabolism. | 2005 | Yakugaku Zasshi | pmid:16327246 |
| Yugar-Toledo JC et al. | Blood pressure circadian rhythm and endothelial function in heavy smokers: acute effects of transdermal nicotine. | 2005 | J Clin Hypertens (Greenwich) | pmid:16330894 |
| Yao X et al. | [The changes of some vasoactive substances after operation in patients with obstructive sleep apnea-hypopnea syndrome]. | 2005 | Lin Chuang Er Bi Yan Hou Ke Za Zhi | pmid:16398051 |
| Kong XY and Gong PL | [Effect of phenolic alkaloids of Menispermum dauricum on thrombosis and platelet aggregation]. | 2005 | Yao Xue Xue Bao | pmid:16408809 |
| Gerasimovska-Kitanovska B et al. | Decreased nitric oxide in women with essential hypertension in prehypertensive phase. | 2005 | Croat. Med. J. | pmid:16342341 |
| Falco A et al. | Inhibition of thromboxane biosynthesis by triflusal in type 2 diabetes mellitus. | 2005 | Atherosclerosis | pmid:16285996 |
| Noguchi M et al. | Enzymologic and pharmacologic profile of loxoprofen sodium and its metabolites. | 2005 | Biol. Pharm. Bull. | pmid:16272692 |
| Ando K | [Synthesis of 2-, 4- and 5-(2-alkylcarbamoyl-1-methylvinyl)-7-alkyloxybenzo[b]furans and their leukotriene B4 receptor antagonistic activity]. | 2005 | Yakugaku Zasshi | pmid:16272807 |
| de Sotomayor MA et al. | Improvement of age-related endothelial dysfunction by simvastatin: effect on NO and COX pathways. | 2005 | Br. J. Pharmacol. | pmid:16231003 |
| Daza L et al. | Captopril effect on prostaglandin E2, thromboxane B2 and proteinuria in lupus nephritis patients. | 2005 | Prostaglandins Other Lipid Mediat. | pmid:16303616 |
| Mason PJ et al. | Plasma, serum, and platelet expression of CD40 ligand in adults with cardiovascular disease. | 2005 | Am. J. Cardiol. | pmid:16275179 |
| Phillips J and Pearce B | Serum deprivation and re-addition: effects on cyclooxygenase inhibitor sensitivity in cultured glia. | 2005 | Inflammopharmacology | pmid:16280096 |
| Gambero A et al. | Comparative study of anti-inflammatory and ulcerogenic activities of different cyclo-oxygenase inhibitors. | 2005 | Inflammopharmacology | pmid:16280097 |