| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arteriosclerosis Obliterans | D001162 | 8 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Arthritis, Juvenile | D001171 | 8 associated lipids |
| Arthus Reaction | D001183 | 8 associated lipids |
| Ascites | D001201 | 25 associated lipids |
| Asthenia | D001247 | 5 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Atrial Fibrillation | D001281 | 16 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Montalescot G et al. | Early thromboxane release during pacing-induced myocardial ischemia with angiographically normal coronary arteries. | 1990 | Am. Heart J. | pmid:2248190 |
| Tomoda H | Development of an experimental model of acute myocardial infarction and the effects of a thromboxane synthetase inhibitor (OKY-046). | 1986 | Am. Heart J. | pmid:3532743 |
| Walinsky P et al. | Thromboxane A2 in acute myocardial infarction. | 1984 | Am. Heart J. | pmid:6485997 |
| O'Connor KM et al. | Effect of thromboxane synthetase inhibition on vulnerability to ventricular arrhythmia following coronary occlusion. | 1986 | Am. Heart J. | pmid:3953390 |
| Austin JC et al. | Thromboxane synthetase inhibition reduces ventricular irritability after coronary occlusion and reperfusion. | 1988 | Am. Heart J. | pmid:3344655 |
| Arora RR et al. | Laser-induced stimulation of thromboxane B2 synthesis in human blood platelets: role of superoxide radicals. | 1993 | Am. Heart J. | pmid:8381256 |
| Cambria RA et al. | Thromboxane synthetase inhibition decreases polymorphonuclear leukocyte activation following hindlimb ischemia. | 1991 | Am Surg | pmid:1847027 |
| Ingster LM and Feinleib M | Salicylate intake and cardiovascular disease: Ingster and Feinleib respond to Hu and Willett. | 1998 | Am J Public Health | pmid:9702172 |
| Satterfield S et al. | Biochemical markers of compliance in the Physicians' Health Study. | 1990 Sep-Oct | Am J Prev Med | pmid:2268456 |
| Natarajan G et al. | Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants. | 2008 | Am J Perinatol | pmid:18726836 |
| Brown HL et al. | Plasma and amniotic fluid prostacyclin and thromboxane in mild pregnancy-induced hypertension. | 1987 | Am J Perinatol | pmid:3566883 |
| Mehta P et al. | Plasma concentrations of thromboxane and prostacyclin metabolites in patients with bone tumors. | 1985 | Am J Pediatr Hematol Oncol | pmid:2994511 |
| Jung TT and Juhn SK | Prostaglandins in human cholesteatoma and granulation tissue. | 1988 | Am J Otol | pmid:3177602 |
| Leese PT et al. | Valdecoxib does not impair platelet function. | 2002 | Am J Emerg Med | pmid:12098171 |
| Andersson T et al. | Evaluation of the pharmacodynamics of acetylsalicylic acid 81 mg with or without esomeprazole 20 mg in healthy volunteers. | 2012 | Am J Cardiovasc Drugs | pmid:22631032 |
| Elissalde MH and Beier RC | Stimulation and release of prostaglandins and thromboxane from macrophages by cotton dust associated lipopolysaccharides. | 1990 | Am Ind Hyg Assoc J | pmid:2270833 |
| Tanaka H et al. | Leukotriene (LT)-receptor antagonist is more effective in asthmatic patients with a low baseline ratio of urinary LTE4 to 2,3-dinor-6-keto-prostaglandin (PG)F1alpha. | 1999 | Allergy | pmid:10380781 |
| Oosaki R et al. | Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma. | 1997 | Allergy | pmid:9188934 |
| Mita H et al. | Possible involvement of mast-cell activation in aspirin provocation of aspirin-induced asthma. | 2001 | Allergy | pmid:11703219 |
| Collins CE et al. | Picotamide inhibition of excess in vitro thromboxane B2 release by colorectal mucosa in inflammatory bowel disease. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791957 |
| Treiber G et al. | The effect of single-dose naproxen on eicosanoid formation in human gastroduodenal mucosa. | 2006 | Aliment. Pharmacol. Ther. | pmid:16393293 |
| Van Hecken A et al. | Effects of enteric-coated, low-dose aspirin on parameters of platelet function. | 2002 | Aliment. Pharmacol. Ther. | pmid:12197849 |
| Cole AT et al. | Low dose aspirin: selective inhibition of rectal dialysis thromboxane B2 in healthy volunteers. | 1994 | Aliment. Pharmacol. Ther. | pmid:7865644 |
| Carty E et al. | Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848666 |
| Wannhoff A et al. | Cardiac volume overload and pulmonary hypertension in long-term follow-up of patients with a transjugular intrahepatic portosystemic shunt. | 2016 | Aliment. Pharmacol. Ther. | pmid:26919285 |
| Signore C et al. | Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day. | 2008 | Alcohol. Clin. Exp. Res. | pmid:18715278 |
| Siler-Khodr TM et al. | Effect of ethanol on thromboxane and prostacyclin production in the human placenta. | 2000 | Alcohol | pmid:10963940 |
| Hillbom M et al. | Effects of ethanol on platelet function. | 1985 May-Jun | Alcohol | pmid:4026960 |
| Shalina RI et al. | [Synthesis of prostaglandins and lipid peroxidation in pregnant women with gestosis]. | 1988 | Akush Ginekol (Mosk) | pmid:3213902 |
| Bashakin NF et al. | [The functional characteristics of the prostacyclin-thromboxane system in newborn infants with a history of acute and chronic intrauterine hypoxia]. | 1993 | Akush Ginekol (Mosk) | pmid:8311150 |
| Fernández-Cruz E et al. | Increased synthesis and production of prostaglandin E2 by monocytes from drug addicts with AIDS. | 1989 | AIDS | pmid:2496725 |
| Patrono C et al. | Radioimmunoassay measurement of stable metabolites of platelet arachidonic acid: a convenient method for the in vitro and ex vivo evaluation of cyclo-oxygenase inhibitors. | 1980 | Agents Actions Suppl. | pmid:6787852 |
| Patrono C et al. | Inhibition of platelet cyclooxygenase by aspirin-like drugs: methods for in vitro and ex vivo assessment. | 1979 | Agents Actions Suppl. | pmid:115255 |
| Chignard M et al. | Arachidonate-mediated bronchoconstriction and platelet activation are inhibited by microgram doses of compound L8027 which are not selective for thromboxane synthetase. | 1979 | Agents Actions Suppl. | pmid:291306 |
| Peskar BA and Holland A | Plasma levels of immunoreactive 15-keto-13,14-dihydro-thromboxane B2 in guinea pigs during anaphylaxis and after histamine injection. | 1979 | Agents Actions Suppl. | pmid:294148 |
| Cerletti C et al. | Comparison of the effects of oral and intravenous aspirin administration on platelet and peripheral vascular cyclo-oxygenase activity: studies in rats and in man. | 1986 | Agents Actions Suppl. | pmid:3101444 |
| Mihai K et al. | Association between total cholesterol and thromboxane B2 levels in offspring of parents suffering from premature coronary artery disease. | 1992 | Agents Actions Suppl. | pmid:1632293 |
| Petö J et al. | Association between total cholesterol and plasma thromboxane B2 in human adults. | 1992 | Agents Actions Suppl. | pmid:1632296 |
| Mentz P and Giessler C | Biosynthesis of TXB2 and 6-oxo-PGF1 alpha in the heart and other tissues under pathophysiological conditions. | 1992 | Agents Actions Suppl. | pmid:1632315 |
| Ghanem NS et al. | The cardiac and renal effects of the complement fragment C5a des Arg are partly mediated by the release of histamine and arachidonic acid metabolites. | 1989 | Agents Actions | pmid:2473617 |
| De Clerck F et al. | Platelet activation by endogenous 5-hydroxytryptamine and histamine released by mast cell degranulation with compound 48/80 in the rat. | 1983 | Agents Actions | pmid:6858790 |
| Nosál R et al. | Antihistaminic drug bromadryl and stimulated platelet aggregation. | 1994 | Agents Actions | pmid:7976789 |
| Zatta A et al. | At low extracellular calcium concentration platelet activating factor induces beta-thromboglobulin release from human platelets through thromboxane-endoperoxides formation. | 1987 | Agents Actions | pmid:2961218 |
| de Clerck F et al. | Inhibition of 5-hydroxytryptamine-induced and -amplified human platelet aggregation by ketanserin (R 41 468), a selective 5-HT2-receptor antagonist. | 1982 | Agents Actions | pmid:6215842 |
| de Clerck F et al. | Inhibition of 5-hydroxytryptamine-induced and -amplified human platelet aggregation by ketanserin (R 41,468), a selective 5-HT2-receptor antagonist. 1982. | 1994 | Agents Actions | pmid:7725978 |
| Cifone MG et al. | Stimulatory effect of hr tumor necrosis factor on TxB2 release by polymorphonuclears and macrophages. | 1986 | Agents Actions | pmid:3825754 |
| Carr DP et al. | Comparison of the systemic inhibition of thromboxane synthesis, anti-inflammatory activity and gastro-intestinal toxicity of non-steroidal anti-inflammatory drugs in the rat. | 1986 | Agents Actions | pmid:3825757 |
| Berti F et al. | Immune release of histamine and other lipid mediators from guinea-pig isolated kidney: antagonism by BN-52021. | 1990 | Agents Actions | pmid:1696776 |
| Nosál R et al. | Effect of chloroquine on isolated mast cells. | 1991 | Agents Actions | pmid:1716835 |
| Conti P et al. | Effect of supernatants from PHA-stimulated and non-stimulated lymphocyte cultures on thromboxane B2 release by polymorphonuclear leukocytes in vitro. | 1985 | Agents Actions | pmid:4003201 |