Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Arteriosclerosis Obliterans D001162 8 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Arthritis, Juvenile D001171 8 associated lipids
Arthus Reaction D001183 8 associated lipids
Ascites D001201 25 associated lipids
Asthenia D001247 5 associated lipids
Asthma D001249 52 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Autoimmune Diseases D001327 27 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Crutchley DJ et al. Enhanced thromboxane B2 release from challenged guinea pig lung after oxygen exposure. 1980 Am. Rev. Respir. Dis. pmid:6155814
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Crutchley DJ et al. Potentiation of thromboxane B2 release from guinea pig lung during anaphylaxis following exposure to 100% O2. 1980 Adv Prostaglandin Thromboxane Res pmid:7377022
Morris HG and Sherman NA Prostaglandin-like substances in urine of asthmatic patients. 1980 Adv Prostaglandin Thromboxane Res pmid:7377024
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Ellwood DA et al. Specific changes in the in vitro production of prostanoids by the ovine cervix at parturition. 1980 Prostaglandins pmid:7384553
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Dejana E et al. Impaired thromboxane production by newly formed platelets after aspirin administration to thrombocytopenic rats. 1980 Br. J. Haematol. pmid:7448129
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Bone EA et al. The effects of strontium and calcium ions on 5-hydroxytryptamine secretion and thromboxane B2 biosynthesis in washed human platelets. 1980 Biochem. Soc. Trans. pmid:7450206
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Best LC et al. The relationship between the production of thromboxane B2 and malondialdehyde by human blood platelets. 1980 Clin. Sci. pmid:7190885
Heggers JP et al. Histological demonstration of prostaglandins and thromboxanes in burned tissue. 1980 J. Surg. Res. pmid:6987462
Vanderhoek JY et al. 15-hydroxy-5,8,11,13-eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase. 1980 J. Biol. Chem. pmid:6771259
Ali M et al. Inhibition of human platelet cyclooxygenase by alpha-tocopherol. 1980 Prostaglandins Med pmid:6771778
Kosaki G et al. The mechanism of the inhibitory effect of protease inhibitors on platelet aggregation and cellular synthesis of prostaglandins. I. The effect on the release of arachidonic acid from phospholipids. 1980 Dec 1-15 Thromb. Res. pmid:6785893
Patrono C et al. Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. 1980 Feb 1-15 Thromb. Res. pmid:7368167
Koh H et al. A radioimmunoassay of thromboxane B2 with thromboxane B2-125I-tyramide and its application to the study on the thromboxane B2 formation during platelet aggregation. 1980 Feb 1-15 Thromb. Res. pmid:7368170
Boyd JA and Eling TE Prostaglandin release and the interaction of platelets with the pulmonary vasculature of rat and guinea pig. 1980 Jul 1-15 Thromb. Res. pmid:7003800
Okamatsu S et al. Effect of calcium channel blockers on arachidonate-induced sudden death in rabbits. 1981 Proc. Soc. Exp. Biol. Med. pmid:6261265
Rao GH et al. Modification of human platelet response to sodium arachidonate by membrane modulation. 1981 Prostaglandins Med pmid:6261286
Roy AC et al. Effect of intravenous infusion of OKY-1581 (sodium-(E)-3-[4-(3-pyridylmethyl)phenyl] -2-methylacrylate) on circulatory thromboxane A2 and prostacyclin levels in anaesthetized baboon. 1981 Prostaglandins Med pmid:7029585
Stuart MJ Effect of endotoxin on arachidonic acid release and thromboxane B2 production by human platelets. 1981 Am. J. Hematol. pmid:7030066
Polley MJ et al. Human complement in the arachidonic acid transformation pathway in platelets. 1981 J. Exp. Med. pmid:7241047
Greenberg S et al. Pulmonary vascular smooth muscle function in porcine splanchnic arterial occlusion shock. 1981 Am. J. Physiol. pmid:7246787
Drake TS et al. Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis. 1981 Am. J. Obstet. Gynecol. pmid:6894667
Halushka PV et al. Protective effects of aspirin in endotoxic shock. 1981 J. Pharmacol. Exp. Ther. pmid:6894770
Ylikorkala O and Viinikka L Prostacyclin, thromboxane, and prostaglandin F2 alpha in maternal plasma during breast-feeding. 1981 Am. J. Obstet. Gynecol. pmid:7011034
Hwang DH Characteristics of the aggregation of platelets and the formation of prostaglandins (PGs) in rat. 1981 Prog. Lipid Res. pmid:7342108
Morrison AR et al. Thromboxane A2 is the major arachidonic acid metabolite of human cortical hydronephrotic tissue. 1981 Prostaglandins pmid:6894498
Halushka PV et al. Increased platelet thromboxane synthesis in diabetes mellitus. 1981 J. Lab. Clin. Med. pmid:7452084
Shaw JO Effects of extracellular Ca2+ and the intracellular Ca2+ antagonist 8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate on rabbit platelet conversion of arachidonic acid into thromboxane. 1981 Prostaglandins pmid:6789402