Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Thrombophilia D019851 6 associated lipids
Endotoxemia D019446 27 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Sepsis D018805 11 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Osteoblastoma D018215 1 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Clark KE et al. Effect of bisenoic prostaglandins and arachidonic acid on the uterine vasculature of pregnant sheep. 1982 Am. J. Obstet. Gynecol. pmid:7065014
Schuette AH et al. Effect of lung thromboxane generation on regional blood flow during sheep bypass. 1982 Am. J. Physiol. pmid:7065206
Mäkilä UM et al. Regulation of prostacyclin and thromboxane production by human umbilical vessels: the effect of estradiol and progesterone in a superfusion model. 1982 Prostaglandins Leukot Med pmid:7043492
Han P et al. Inhibition of platelet function of antiarrhythmic drugs, verapamil and disopyramide. 1982 Thromb. Haemost. pmid:7101234
Krausz MM et al. Adverse effects of prostacyclin used to perfuse isolated lung lobes. 1982 Am. J. Physiol. pmid:7044149
Hirsh PD et al. Influence of blood sampling site and technique on thromboxane concentrations in patients with ischemic heart disease. 1982 Am. Heart J. pmid:7102506
Siess W et al. Plasma catecholamines, platelet aggregation and associated thromboxane formation after physical exercise, smoking or norepinephrine infusion. 1982 Circulation pmid:7044612
Chierchia S et al. Failure of thromboxane A2 blockade to prevent attacks of vasospastic angina. 1982 Circulation pmid:7116586
Sasagawa S et al. Effects of thromboxane A2 injection on the rabbit coronary artery. I. Physiologic effects in healthy animals. 1982 Exp. Mol. Pathol. pmid:7117494
Socini A et al. Effects of the coumarin derivative AD6 on platelet aggregation, platelet vessel wall interactions and 6 keto PGF1 alpha production in perfused aortas, in experimentally hypercholesterolaemic rabbits. 1982 Pharmacol Res Commun pmid:7048340
Simpson RM et al. Generation of thromboxane A2 and aorta-contracting activity from platelets stimulated with modified C-reactive protein. 1982 Immunology pmid:7118160
Leach CM and Thorburn GD A comparative study of collagen induced thromboxane release from platelets of different species: implications for human atherosclerosis models. 1982 Prostaglandins pmid:7122912
Bottoms GD et al. Thromboxane, prostaglandin I2 (epoprostenol), and the hemodynamic changes in equine endotoxin shock. 1982 Am. J. Vet. Res. pmid:7049018
Poubelle P et al. [Mononucleated phagocytes from rheumatoid synovial fluid. Synthesis of prostanoids and first pharmacological applications]. 1982 Rev Rhum Mal Osteoartic pmid:7123126
Homma T and Malik KU Effect of prostaglandins on pancreatic circulation in anesthetized dogs. 1982 J. Pharmacol. Exp. Ther. pmid:7050343
Bradlow BA and Chetty N Dosage frequency for suppression of platelet function by low dose aspirin therapy. 1982 Thromb. Res. pmid:7123514
Peterson MB et al. Thromboxane mediates acute pulmonary hypertension in sheep extracorporeal perfusion. 1982 Am. J. Physiol. pmid:7051860
Martin JF et al. Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique. 1982 Thromb. Res. pmid:6814004
Fletcher MS et al. Endotoxin, prostaglandins and renal fibrin deposition in obstructive jaundice. 1982 Br J Surg pmid:6751458
Dejana E et al. Bleeding time in rats: a comparison of different experimental conditions. 1982 Thromb. Haemost. pmid:6753230
Strano A et al. Platelet sensitivity to prostacyclin and thromboxane production in hyperlipidemic patients. 1982 Thromb. Haemost. pmid:6753232
Numano F et al. Effects of thromboxane A2 injection on the rabbit coronary artery. II. The production of infarcts in cholesterol-fed animals. 1982 Exp. Mol. Pathol. pmid:6956517
Flynn JT and Demling RH Inhibition of endogenous thromboxane synthesis by exogenous prostacyclin during endotoxemia in conscious sheep. 1982 Adv Shock Res pmid:6753534
Smith MC et al. Prostacyclin substitution for heparin in long-term hemodialysis. 1982 Am. J. Med. pmid:6753575
Aharony D et al. Regulation of arachidonate-induced platelet aggregation by the lipoxygenase product, 12-hydroperoxyeicosatetraenoic acid. 1982 Biochim. Biophys. Acta pmid:6814496
Ylikorkala O et al. Prostacyclin and thromboxane in chronic uremia: effect of hemodialysis. 1982 Clin. Nephrol. pmid:6754193
Ylikorkala O et al. Production of prostacyclin and thromboxane during cesarean section. 1982 Obstet Gynecol pmid:6755324
Hamasaki Y et al. Hypoxia stimulates prostacyclin generation by dog lung in vitro. 1982 Prostaglandins Leukot Med pmid:7051045
Goldsmith JC and Needleman SW A comparative study of thromboxane and prostacyclin release from ex vivo and cultured bovine vascular endothelium. 1982 Prostaglandins pmid:6815717
De Caterina R et al. [Effects of isosorbide dinitrate on platelet aggregation and production of thromboxane B2]. 1982 Cardiologia pmid:6892461
Ody C et al. 6-Ketoprostaglandin F1 alpha, prostaglandins E2, F2 alpha and thromboxane B2 production by endothelial cells, smooth muscle cells and fibroblasts cultured from piglet aorta. 1982 Biochim. Biophys. Acta pmid:6214281
Mari D et al. Coagulation and platelet activation after retinal vein occlusions. 1982 Haemostasis pmid:6215293
de Clerck F et al. Inhibition of 5-hydroxytryptamine-induced and -amplified human platelet aggregation by ketanserin (R 41 468), a selective 5-HT2-receptor antagonist. 1982 Agents Actions pmid:6215842
Mehta J and Mehta P Effects of propranolol therapy on platelet release and prostaglandin generation in patients with coronary heart disease. 1982 Circulation pmid:6216027
Mehta P et al. Thromboxane and prostacyclin generation by intact human vessels in response to balloon catheter trauma. 1982 Prostaglandins Leukot Med pmid:6217465
Randall MJ and Wilding RI Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with thromboxane synthetase inhibitor dazoxiben hydrochloride, (UK-37, 248-01). 1982 Thromb. Res. pmid:6897751
De Caterina R et al. [Effect of isosorbide dinitrate on platelet aggregation and production of thromboxane B2]. 1982 Cardiologia pmid:6927441
Davì G et al. [Effects of flurbiprofen on platelet function in patients with ischemic cardiomyopathy]. 1982 Cardiologia pmid:6927457
Whinnery MA et al. Thromboxane B2 and prostaglandin E2 in the rat kidney with unilateral ureteral obstruction. 1982 Am. J. Physiol. pmid:6950670
Hornych A et al. [Urinary thromboxane B2 in hypertensive patients]. 1982 Arch Mal Coeur Vaiss pmid:6810812
Meydani SN and Dupont J Effect of zinc deficiency on prostaglandin synthesis in different organs of the rat. 1982 J. Nutr. pmid:7045297
Jackson CA et al. Relationship between platelet aggregation, thromboxane synthesis and albumin concentration in nephrotic syndrome. 1982 Br. J. Haematol. pmid:6810912
Michelassi F et al. Leukotriene D4: a potent coronary artery vasoconstrictor associated with impaired ventricular contraction. 1982 Science pmid:6808665
Landgraf-Leurs MM et al. Aggregation and thromboxane formation by platelets and vascular prostacyclin production from BB rats. An animal model for type I diabetes. 1982 Prostaglandins pmid:6812171
Nugent WC et al. Prostaglandin response to intravenous nitroglycerin. 1982 J. Surg. Res. pmid:6810023
Miller JL et al. Arachidonic acid metabolism in guinea pig megakaryocytes. 1982 Biochem. Biophys. Res. Commun. pmid:6812584
Rothberg KG and Hitchcock M In vitro biosynthesis of cyclooxygenase metabolites in ovalbumin-sensitized and control lungs of guinea pigs. 1982 Biochem. Pharmacol. pmid:6812589
Robinson C et al. Thromboxane B2 uptake and metabolism in isolated perfused lung. Identification and comparison with prostaglandin F2 alpha. 1982 Biochim. Biophys. Acta pmid:6751406
Schafer AI et al. Platelet lipoxygenase-dependent oxygen burst. Evidence for differential activation of lipoxygenase in intact and disrupted human platelets. 1982 Biochim. Biophys. Acta pmid:6812645
Ylikorkala O et al. The effect of oral contraceptives on antiaggregatory prostacyclin and proaggregatory thromboxane A2 in humans. 1982 Am. J. Obstet. Gynecol. pmid:7036746