| MeSH term | MeSH ID | Detail |
|---|---|---|
| Thrombophilia | D019851 | 6 associated lipids |
| Endotoxemia | D019446 | 27 associated lipids |
| Pancreatitis, Acute Necrotizing | D019283 | 18 associated lipids |
| Atrial Premature Complexes | D018880 | 1 associated lipids |
| Sepsis | D018805 | 11 associated lipids |
| Systemic Inflammatory Response Syndrome | D018746 | 4 associated lipids |
| Ventricular Dysfunction, Left | D018487 | 33 associated lipids |
| Osteoblastoma | D018215 | 1 associated lipids |
| Aortic Aneurysm, Abdominal | D017544 | 5 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fitzpatrick FA | A radioimmunoassay for thromboxane B2. | 1982 | Meth. Enzymol. | pmid:7132759 |
| Maas RL et al. | Quantitative assay of urinary 2,3-dinor thromboxane B2 by GC-MS. | 1982 | Meth. Enzymol. | pmid:7132771 |
| Pace-Asciak CR and Edwards NS | Preparation of 2,3,4,5-tetranor-thromboxane B2, the major urinary catabolite of thromboxane B2 in the rat. | 1982 | Meth. Enzymol. | pmid:7132772 |
| Martin JF et al. | Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique. | 1982 | Thromb. Res. | pmid:6814004 |
| Hadding U et al. | Peritoneal macrophages release prostaglandin E and thromboxane B2 in response to C3b. | 1982 | Adv. Exp. Med. Biol. | pmid:7158499 |
| Addonizio VP et al. | Inhibition of human platelet function by verapamil. | 1982 | Thromb. Res. | pmid:7164035 |
| Vargaftig BB et al. | Adrenaline and PAF-acether synergize to trigger cyclooxygenase-independent activation of plasma-free human platelets. | 1982 | Thromb. Res. | pmid:7164036 |
| Vlodavsky I et al. | Platelet interaction with the extracellular matrix produced by cultured endothelial cells: a model to study the thrombogenicity of isolated subendothelial basal lamina. | 1982 | Thromb. Res. | pmid:7179215 |
| Deby-Dupont G et al. | Release of thromboxane B2 during adult respiratory distress syndrome and its inhibition by non steroidal anti-inflammatory substances in man. | 1982 | Arch Int Pharmacodyn Ther | pmid:7181589 |
| Goldsmith JC and Needleman SW | A comparative study of thromboxane and prostacyclin release from ex vivo and cultured bovine vascular endothelium. | 1982 | Prostaglandins | pmid:6815717 |
| Blackwell GJ et al. | Prostacyclin prolongs viability of washed human platelets. | 1982 | Biochim. Biophys. Acta | pmid:6291622 |
| Karmali RA et al. | Prostaglandin regulation of murine mammary tumor virus production: a basis for some of the glucocorticoid and prolactin actions on mammary tumor cell cultures. | 1982 | Prostaglandins Leukot Med | pmid:6296884 |
| Castaldi PA et al. | Evidence for a platelet membrane defect in the myeloproliferative syndromes. | 1982 | Thromb. Res. | pmid:6960545 |
| Rachmilewitz D et al. | Prostanoid synthesis by cultured peripheral blood mononuclear cells in inflammatory diseases of the bowel. | 1982 | Gastroenterology | pmid:6949849 |
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| Rock JA et al. | Cul-de-sac fluid in women with endometriosis: fluid volume and prostanoid concentration during the proliferative phase of the cycle--days 8 to 12. | 1982 | Fertil. Steril. | pmid:6953017 |
| Casey LC et al. | Prevention of endotoxin-induced pulmonary hypertension in primates by the use of a selective thromboxane synthetase inhibitor, OKY 1581. | 1982 | J. Pharmacol. Exp. Ther. | pmid:6896528 |
| Chen LS et al. | Changes of plasma 6-keto-PGF1 alpha and thromboxane B2 levels and platelet aggregation after tourniquet ischemia on the upper limb in normal subjects and patients with ischemic heart disease. | 1982 | Jpn. Circ. J. | pmid:6896534 |
| Evans CA et al. | Gestational changes in prostanoid concentrations in intrauterine tissues and fetal fluids from pregnant sheep, and the relation to prostanoid output in vitro. | 1982 | Biol. Reprod. | pmid:6896829 |
| Koyama I et al. | Release of 6-keto-prostaglandin F1 alpha and thromboxane B2 from mouse peritoneal macrophages during their adhesion and spreading on a glass surface. | 1982 | Prostaglandins | pmid:6896924 |
| Uderman HD et al. | Attenuation of the development of hypertension in spontaneously hypertensive rats by the thromboxane synthetase inhibitor, 4'-(imidazol-1-yl) acetophenone. | 1982 | Prostaglandins | pmid:6897296 |
| Katsumata M et al. | Diphenylhydantoin: an alternative ligand of a glucocorticoid receptor affecting prostaglandin generation in A/J mice. | 1982 | Science | pmid:6897299 |
| Meydani SN and Dupont J | Effect of zinc deficiency on prostaglandin synthesis in different organs of the rat. | 1982 | J. Nutr. | pmid:7045297 |
| Cerletti C et al. | Non-steroidal anti-inflammatory drugs react with two sites on platelet cyclo-oxygenase. Evidence from "in vivo" drug interaction studies in rats. | 1982 | Biochim. Biophys. Acta | pmid:6799004 |
| Levy-Toledano S et al. | Human platelet activation in the absence of aggregation: a calcium-dependent phenomenon independent of thromboxane formation. | 1982 | Blood | pmid:6803854 |
| Landgraf-Leurs MM et al. | Aggregation and thromboxane formation by platelets and vascular prostacyclin production from BB rats. An animal model for type I diabetes. | 1982 | Prostaglandins | pmid:6812171 |
| Bodzenta A et al. | Platelet malondialdehyde and plasma thromboxane B2 formation in patients with obliterative arteriosclerosis of the lower limbs. | 1982 | Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. | pmid:6188668 |
| Harada Y et al. | Changes in the levels of prostaglandins and thromboxane and their roles in the accumulation of exudate in rat carrageenin-induced pleurisy--a profile analysis using gas chromatography-mass spectrometry. | 1982 | Prostaglandins | pmid:6889754 |
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| Miller JL et al. | Arachidonic acid metabolism in guinea pig megakaryocytes. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6812584 |
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| Uyama O et al. | Plasma concentrations of 6-keto-prostaglandin F1 alpha in patients with hypertension, cerebrovascular disease or Takayasu's arteritis. | 1982 Jan 1-15 | Thromb. Res. | pmid:6121391 |
| Sakai K et al. | Roles of endogenous prostacyclin and thromboxane A2 in the ischemic canine heart. | 1982 Jan-Feb | J. Cardiovasc. Pharmacol. | pmid:6176788 |
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| Shohami E et al. | The effect of incomplete cerebral ischemia on prostaglandin levels in rat brain. | 1982 Jul-Aug | Stroke | pmid:6896589 |
| Mest HJ et al. | [Effect of stress on blood level of prostaglandins in students during exams]. | 1982 May-Jun | Farmakol Toksikol | pmid:7095121 |
| Simmons PM et al. | The release of leukotriene B4 during experimental inflammation. | 1983 | Biochem. Pharmacol. | pmid:6305369 |
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| Hartung HP and Toyka KV | Activation of macrophages by substance P: induction of oxidative burst and thromboxane release. | 1983 | Eur. J. Pharmacol. | pmid:6191998 |
| Menys VC and Davies JA | Selective inhibition of thromboxane synthetase with dazoxiben - basis of its inhibitory effect on platelet adhesion. | 1983 | Thromb. Haemost. | pmid:6346575 |
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| Sanders TA and Hochland MC | A comparison of the influence on plasma lipids and platelet function of supplements of omega 3 and omega 6 polyunsaturated fatty acids. | 1983 | Br. J. Nutr. | pmid:6639916 |
| Mehta JL | Prostaglandins: regulatory role in cardiovascular system and implications in ischemic heart disease. | 1983 | Int. J. Cardiol. | pmid:6642760 |
| Patel K and Bakhle YS | Thromboxane B2 (TxB2) metabolism in rat isolated lung and its inhibition by drugs. | 1983 | Prostaglandins Leukot Med | pmid:6573689 |
| Okahara T et al. | Zonal heterogeneity of prostaglandin and thromboxane release in the dog kidney. | 1983 | Prostaglandins | pmid:6575405 |
| Butler RR et al. | Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production. | 1983 | J. Pharmacol. Exp. Ther. | pmid:6339712 |