Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Thrombophilia D019851 6 associated lipids
Endotoxemia D019446 27 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Sepsis D018805 11 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Osteoblastoma D018215 1 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Mäkilä UM et al. Relation between umbilical prostacyclin production and blood-flow in the fetus. 1983 Lancet pmid:6132081
Thorngren M et al. Thromboxane A2 in skin-bleeding-time blood and in clotted venous blood before and after administration of acetylsalicylic acid. 1983 Lancet pmid:6133107
Stenson WF and Lobos E Inhibition of platelet thromboxane synthetase by sulfasalazine. 1983 Biochem. Pharmacol. pmid:6135423
Johnsen SA et al. Conversion of arachidonic acid in human maternal and neonatal mononuclear leukocytes. 1983 Immunol. Lett. pmid:6411611
Rotmensch HH et al. Plasma platelet products and exercise-induced myocardial ischemia. 1983 J. Lab. Clin. Med. pmid:6854135
Hamelin SS and Chan AC Modulation of platelet thromboxane and malonaldehyde by dietary vitamin E and linoleate. 1983 Lipids pmid:6855486
De Clerck F et al. Platelet activation by endogenous 5-hydroxytryptamine and histamine released by mast cell degranulation with compound 48/80 in the rat. 1983 Agents Actions pmid:6858790
Preston FE Aspirin, prostaglandins, and peripheral gangrene. 1983 Am. J. Med. pmid:6859070
Winter M et al. Synthesis of thromboxane B2 in uraemia and the effects of dialysis. 1983 Thromb. Res. pmid:6868024
Tanganelli I et al. [Thromboxane, beta-thromboglobulin and the degree of blood sugar control in type 1 diabetes mellitus]. 1983 Boll. Soc. Ital. Biol. Sper. pmid:6194801
Capodicasa G et al. Platelet thromboxane formation and BTG levels after intensive charcoal HP in uremics or regular hemodialytic treatment (RHT). 1983 Int J Artif Organs pmid:6195116
Ditter H et al. Effects of prostacyclin during cardiopulmonary bypass in men on plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2, 6-keto-prostaglandin F1 alpha and heparin. 1983 Thromb. Res. pmid:6197766
Lismonde M et al. [The presence of 6-oxo-PGF1alpha and thromboxane B2 in peritoneal exudates released by iota-carrageenan in the rat]. 1983 Arch. Int. Physiol. Biochim. pmid:6198994
Roth DM et al. Protective actions of ibuprofen in arachidonate-induced sudden death. 1983 Pharmacology pmid:6413987
Salmon JA et al. Synthesis of arachidonate cyclo-oxygenase products by rheumatoid and nonrheumatoid synovial lining in nonproliferative organ culture. 1983 Ann. Rheum. Dis. pmid:6402992
Horellou MH et al. Familial and constitutional bleeding disorder due to platelet cyclo-oxygenase deficiency. 1983 Am. J. Hematol. pmid:6404162
Di Minno G et al. Exposure of platelet fibrinogen-binding sites by collagen, arachidonic acid, and ADP: inhibition by a monoclonal antibody to the glycoprotein IIb-IIIa complex. 1983 Blood pmid:6216929
Reeves WC et al. The release of thromboxane A2 and prostacyclin following experimental acute pulmonary embolism. 1983 Prostaglandins Leukot Med pmid:6348800
Aznavoorian SA et al. Prostacyclin inhibits 5-hydroxytryptamine release but stimulates thromboxane synthesis during cardiopulmonary bypass. 1983 Prostaglandins pmid:6348886
Ahlquist DA et al. Factors influencing metabolism of arachidonic acid in guinea pig gastric mucosa. 1983 Am. J. Physiol. pmid:6401937
Buchanan MR et al. The sex-related differences in aspirin pharmacokinetics in rabbits and man and its relationship to antiplatelet effects. 1983 Thromb. Res. pmid:6221436
Kaar ML et al. Prostacyclin and thromboxane in diabetic children. 1983 Prostaglandins Leukot Med pmid:6351104
Parry MJ Effects of thromboxane synthetase inhibition on arachidonate metabolism and platelet behaviour. 1983 Br J Clin Pharmacol pmid:6401997
Yamamoto S et al. Enzyme immunoassay of thromboxane B2 and 6-keto-prostaglandin F1 alpha as a substitute for radioimmunoassay. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221523
Fischer S et al. The influence of selective thromboxane synthetase inhibition with a novel imidazole derivative, UK-38,485, on prostanoid formation in man. 1983 Circulation pmid:6352080
Davi' G et al. Platelet activation after adrenergic stimulation in hypertensive patients: effects of acebutolol. 1983 Eur. Heart J. pmid:6352266
Jakubowski JA et al. Arachidonic acid metabolism by platelets of differing size. 1983 Br. J. Haematol. pmid:6402003
FitzGerald GA et al. Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man. 1983 J. Clin. Invest. pmid:6355181
Zijlstra FJ et al. Thrombotic thrombocytopenic purpura and plasma thromboxane B2 levels. 1983 Thromb. Res. pmid:6684333
Lianos EA et al. Glomerular prostaglandin and thromboxane synthesis in rat nephrotoxic serum nephritis. Effects on renal hemodynamics. 1983 J. Clin. Invest. pmid:6685136
Wynalda MA et al. Sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate (U-63557A), a new, selective thromboxane synthase inhibitor: intravenous and oral pharmacokinetics in dogs and correlations with ex situ thromboxane B2 production. 1983 Prostaglandins pmid:6685888
McDonald JW et al. Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep. 1983 Circ. Res. pmid:6687354
Randall MJ and Wilding RI Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with dazoxiben hydrochloride (UK 37,248-01). 1983 Br J Clin Pharmacol pmid:6687429
Bruckner G et al. Dietary trilinoelaidate: effects on hematological parameters, serum eicosanoids and tissue fatty acid composition in rats. 1983 J. Nutr. pmid:6687476
Mathieson MA et al. Ischemia of the limb stimulates thromboxane production and myocardial depression. 1983 Surg Gynecol Obstet pmid:6648769
Barrett PA and Butler KD Shortening of platelet survival by induced hypercholesterolaemia in rabbits and its prolongation by anagrelide. 1983 Thromb. Haemost. pmid:6648889
Robinson C and Hoult JR Thromboxane A2 analogues inhibit the metabolism of thromboxane B2 in perfused guinea-pig lung. 1983 Biochim. Biophys. Acta pmid:6652102
Higgs GA et al. The source of thromboxane and prostaglandins in experimental inflammation. 1983 Br. J. Pharmacol. pmid:6652359
Anton RF et al. In vivo regional levels of PGE and thromboxane in mouse brain: effect of decapitation, focused microwave fixation, and indomethacin. 1983 Prostaglandins pmid:6658001
Mahoney D et al. Influence of dietary polyunsaturated fatty acids on renal & aortic prostaglandin synthesis in 1 kidney 1 clip Goldblatt hypertensive rats. 1983 Prostaglandins pmid:6658002
Socini A et al. Fish oil administration as a supplement to a corn oil containing diet affects arterial prostacyclin production more than platelet thromboxane formation in the rat. 1983 Prostaglandins pmid:6310702
Gethmann U et al. Effect of catecholestrogens on prostaglandin release by rat pituitaries superfused in vitro. 1983 Arch. Gynecol. pmid:6320749
Davì G et al. Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients. 1983 Prostaglandins Leukot Med pmid:6573692
Lieb J et al. Elevated levels of prostaglandin E2 and thromboxane B2 in depression. 1983 Prostaglandins Leukot Med pmid:6574523
Coceani F et al. Prostaglandin E2 and thromboxane B2 in cerebrospinal fluid of afebrile and febrile cat. 1983 Am. J. Physiol. pmid:6574712
Viinikka L et al. Effect of prolonged treatment with acetylsalicylic acid and dipyridamole on platelet thromboxane A2 production in atherosclerotic subjects. 1983 Prostaglandins Leukot Med pmid:6576385
Fukumoto S and Tanaka K Protective effects of thromboxane A2 synthetase inhibitors on endotoxin shock. 1983 Prostaglandins Leukot Med pmid:6576388
Kinney EL et al. Mechanism of action of amrinone: role of thromboxane synthetase inhibition. 1983 Prostaglandins Leukot Med pmid:6576389
Roy L et al. Increased plasma concentrations of prostacyclin metabolite 6-keto-PGF1 alpha in essential hypertension. Influence of therapy with labetalol. 1983 Am. J. Cardiol. pmid:6823861
Asbóth G et al. Conversion of arachidonic acid to prostanoids in the avian uterus. 1983 Biochim. Biophys. Acta pmid:6402032